当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Ventricular tachycardia in the infarcted, Langendorff-perfused human heart: role of the arrangement of surviving cardiac fibers.

Ventricular tachycardia in the infarcted, Langendorff-perfused human heart: role of the arrangement of surviving cardiac fibers.

Abstract：

:Electrophysiologic and histologic studies were performed on Langendorff-perfused human hearts from patients who underwent heart transplantation because of extensive infarction. In nine hearts, 15 sustained ventricular tachycardias could be induced by programmed stimulation. In all hearts, mapping of epicardial and endocardial electrical activity during tachycardia was carried out. Histologic examination of the infarcted area between the site of latest activation of one cycle and the site of earliest activation of the next cycle revealed zones of viable myocardial tissue. In two hearts in which the time gap between latest and earliest activation was small, surviving myocardial tissue constituted a continuous tract that traversed the infarct. In three other hearts in which the time gap was large, surviving tissue consisted of parallel bundles that coursed separately over a few hundred micrometers, then merged into a single bundle and finally branched again. The direction of the fibers within the bundles was perpendicular to the direction of the activation front in that area. A similar type of inhomogeneous anisotrophy and activation delay was found in an infarcted papillary muscle removed from one of the explanted hearts and studied in a tissue bath during basic stimulation. Histologic examination of this preparation revealed that the delay was caused by a zigzag route of activation over branching and merging bundles of surviving myocytes separated by connective tissue.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

de Bakker JM,Coronel R,Tasseron S,Wilde AA,Opthof T,Janse MJ,van Capelle FJ,Becker AE,Jambroes G

doi

10.1016/0735-1097(90)92832-m

subject

Has Abstract

pub_date

1990-06-01 00:00:00

pages

1594-607

issue

7

eissn

0735-1097

issn

1558-3597

pii

0735-1097(90)92832-M

journal_volume

15

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Intracellular calcium transients in human working myocardium as detected with aequorin.

    abstract：:The calcium transients associated with contraction in human working myocardium were recorded by use of the bioluminescent protein, aequorin, a substance that emits light when it combines with calcium ion (Ca++). Small amounts of aequorin were microinjected into superficial cells of human atrial and ventricular muscle ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(84)80028-5

    authors： Morgan JP,Chesebro JH,Pluth JR,Puga FJ,Schaff HV

    更新日期：1984-02-01 00:00:00

  • Nonthoracotomy internal defibrillation in dogs: threshold reduction using a subcutaneous chest wall electrode with a transvenous catheter electrode.

    abstract：:The efficacy of truncated exponential waveform shocks using a cardioverter-defibrillator catheter with and without a 13.9 cm2 subcutaneous thoracic patch electrode was examined in 10 pentobarbital-anesthetized dogs. The cardioverter-defibrillator catheter was positioned through the external jugular vein with the dista...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80025-6

    authors： Wetherbee JN,Chapman PD,Klopfenstein HS,Bach SM Jr,Troup PJ

    更新日期：1987-08-01 00:00:00

  • Inappropriate sinus tachycardia.

    abstract：:Inappropriate sinus tachycardia (IST) is a syndrome in which the sinus heart rate is inexplicably faster than expected and associated symptoms are present. The heart rate at rest, even in a supine position, can exceed 100 beats/min; minimal activity accelerates the rate rapidly and substantially. Patients with IST may...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2012.07.074

    authors： Olshansky B,Sullivan RM

    更新日期：2013-02-26 00:00:00

  • Long-term follow-up (12 to 35 weeks) after dynamic cardiomyoplasty.

    abstract：OBJECTIVES:To obtain information on the long-term effects of dynamic cardiomyoplasty on hemodynamics and muscle histology, this surgical method was evaluated in goats. BACKGROUND:Dynamic cardiomyoplasty has been introduced as a new method to treat patients with severe cardiac failure. METHODS:In 24 goats, the left la...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90188-7

    authors： Lucas CM,Van der Veen FH,Cheriex EC,Lorusso R,Havenith M,Penn OC,Wellens HJ

    更新日期：1993-09-01 00:00:00

  • Coexistent pulmonary and portal hypertension: morphologic and clinical features.

    abstract：:Patients with portal hypertension of varying etiology may develop pulmonary artery hypertension. In the present autopsy study, pulmonary and hepatic tissue was studied in 12 patients in whom pulmonary and portal hypertension coexisted. Plexogenic pulmonary arteriopathy was present in 10 patients, 7 of whom had coexist...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80123-7

    authors： Edwards BS,Weir EK,Edwards WD,Ludwig J,Dykoski RK,Edwards JE

    更新日期：1987-12-01 00:00:00

  • The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study.

    abstract：OBJECTIVES:This is a randomized controlled study of anemic patients with severe congestive heart failure (CHF) to assess the effect of correction of the anemia on cardiac and renal function and hospitalization. BACKGROUND:Although mild anemia occurs frequently in patients with CHF, there is very little information abo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(01)01248-7

    authors： Silverberg DS,Wexler D,Sheps D,Blum M,Keren G,Baruch R,Schwartz D,Yachnin T,Steinbruch S,Shapira I,Laniado S,Iaina A

    更新日期：2001-06-01 00:00:00

  • Relationship between renal function and plasma brain natriuretic peptide in patients with heart failure.

    abstract：OBJECTIVES:This study sought to evaluate the relationship between brain natriuretic peptide (BNP), renal function, and the severity of congestive heart failure (CHF). BACKGROUND:Both BNP and renal function are prognostic predictors in CHF patients. METHODS:We measured the plasma BNP level in the aortic root and coron...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2005.10.038

    authors： Tsutamoto T,Wada A,Sakai H,Ishikawa C,Tanaka T,Hayashi M,Fujii M,Yamamoto T,Dohke T,Ohnishi M,Takashima H,Kinoshita M,Horie M

    更新日期：2006-02-07 00:00:00

  • Lipoprotein cholesterol, apolipoprotein A-I and B and lipoprotein (a) abnormalities in men with premature coronary artery disease.

    abstract：:The prevalence of abnormalities of lipoprotein cholesterol and apolipoproteins A-I and B and lipoprotein (a) [Lp(a)] was determined in 321 men (mean age 50 +/- 7 years) with angiographically documented coronary artery disease and compared with that in 901 control subjects from the Framingham Offspring Study (mean age ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(92)90520-w

    authors： Genest J Jr,McNamara JR,Ordovas JM,Jenner JL,Silberman SR,Anderson KM,Wilson PW,Salem DN,Schaefer EJ

    更新日期：1992-03-15 00:00:00

  • Validation of a digital color Doppler flow measurement method for pulmonary regurgitant volumes and regurgitant fractions in an in vitro model and in a chronic animal model of postoperative repaired tetralogy of Fallot.

    abstract：OBJECTIVES:The purpose of this study was to validate a digital color Doppler (DCD) automated cardiac flow measurement method for quantifying pulmonary regurgitation (PR) in an in vitro and a chronic animal model of the right ventricular outflow tract of postoperative tetralogy of Fallot (TOF). BACKGROUND:There has bee...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)01106-2

    authors： Mori Y,Irvine T,Jones M,Rusk RA,Pham Q,Kenny A,Sahn DJ

    更新日期：2001-02-01 00:00:00

  • A randomized comparison of paclitaxel-eluting stents versus bare-metal stents for treatment of unprotected left main coronary artery stenosis.

    abstract：OBJECTIVES:To optimize percutaneous coronary intervention (PCI) strategy for unprotected left main (LM) disease, we performed a randomized study: intravascular ultrasound (IVUS)-guided bare-metal stent (BMS) or paclitaxel-eluting stent (PES) implantation after lesion pre-treatment with cutting balloon (CB) for unprotec...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2007.03.055

    authors： Erglis A,Narbute I,Kumsars I,Jegere S,Mintale I,Zakke I,Strazdins U,Saltups A

    更新日期：2007-08-07 00:00:00

  • Public reporting of clinical quality data: an update for cardiovascular specialists.

    abstract：:Public reporting of hospital and individual provider quality of care measures is not a new concept. In the United States, the first national public reports of hospital mortality data occurred in 1986, and detailed physician-level data for cardiac surgery are now reported in 4 states. The development of the "Hospital C...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2013.11.050

    authors： Dehmer GJ,Drozda JP Jr,Brindis RG,Masoudi FA,Rumsfeld JS,Slattery LE,Oetgen WJ

    更新日期：2014-04-08 00:00:00

  • Silent ischemia during coronary occlusion produced by balloon inflation: relation to regional myocardial dysfunction.

    abstract：:Thirty patients with stable exertional angina undergoing percutaneous transluminal coronary angioplasty of an isolated obstructive lesion of the proximal left anterior descending artery were prospectively evaluated to investigate the relation between angina induced by balloon inflation and the quantity and severity of...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80189-4

    authors： Wohlgelernter D,Jaffe CC,Cabin HS,Yeatman LA Jr,Cleman M

    更新日期：1987-09-01 00:00:00

  • The diastolic flow-pressure gradient relation in coronary stenoses in humans.

    abstract：OBJECTIVES:We assessed the feasibility and reproducibility of the instantaneous diastolic coronary flow velocity-pressure gradient relation to characterize different degrees of coronary stenoses. BACKGROUND:Assessment of the hemodynamic significance of coronary stenoses can be difficult. Using sensor-tipped guidewires...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(02)01834-x

    authors： Marques KM,Spruijt HJ,Boer C,Westerhof N,Visser CA,Visser FC

    更新日期：2002-05-15 00:00:00

  • The association of differing measures of overweight and obesity with prevalent atherosclerosis: the Dallas Heart Study.

    abstract：OBJECTIVES:This study sought to evaluate the associations between different measures of obesity and prevalent atherosclerosis in a large population-based cohort. BACKGROUND:Although obesity is associated with cardiovascular mortality, it is unclear whether this relationship is mediated by increased atherosclerotic bur...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.04.066

    authors： See R,Abdullah SM,McGuire DK,Khera A,Patel MJ,Lindsey JB,Grundy SM,de Lemos JA

    更新日期：2007-08-21 00:00:00

  • A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques.

    abstract：OBJECTIVES:The aim of this study was to understand the initial mechanism of arterial thrombus formation induced by vulnerable human atherosclerotic plaques to re-assess and improve current antithrombotic strategies. BACKGROUND:Rupture of atherosclerotic plaques causes arterial thrombus formation that might lead to myo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2009.11.051

    authors： Reininger AJ,Bernlochner I,Penz SM,Ravanat C,Smethurst P,Farndale RW,Gachet C,Brandl R,Siess W

    更新日期：2010-03-16 00:00:00

  • Pulmonary artery growth after palliation of congenital heart disease with duct-dependent pulmonary circulation: arterial duct stenting versus surgical shunt.

    abstract：OBJECTIVES:The aim of this study was to compare the pulmonary artery (PA) growth after arterial duct (AD) stenting versus modified Blalock-Taussig shunt (MBTS) in neonates with congenital heart disease with duct-dependent pulmonary circulation (CHD-DPC). BACKGROUND:Arterial duct stenting is increasingly deemed a relia...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2009.07.043

    authors： Santoro G,Capozzi G,Caianiello G,Palladino MT,Marrone C,Farina G,Russo MG,Calabrò R

    更新日期：2009-12-01 00:00:00

  • Short-Term Exposure to Ambient Air Pollution and Mortality From Myocardial Infarction.

    abstract：BACKGROUND:Short-term exposure to ambient air pollution has been linked to occurrence of myocardial infarction (MI); however, only a limited number of studies investigated its association with death from MI, and the results remain inconsistent. OBJECTIVES:This study sought to investigate the association of short-term ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2020.11.033

    authors： Liu Y,Pan J,Fan C,Xu R,Wang Y,Xu C,Xie S,Zhang H,Cui X,Peng Z,Shi C,Zhang Y,Sun H,Zhou Y,Zhang L

    更新日期：2021-01-26 00:00:00

  • Head-to-head comparison of left ventricular function assessment with 64-row computed tomography, biplane left cineventriculography, and both 2- and 3-dimensional transthoracic echocardiography: comparison with magnetic resonance imaging as the reference s

    abstract：OBJECTIVES:This study was designed to compare the accuracy of 64-row contrast computed tomography (CT), invasive cineventriculography (CVG), 2-dimensional echocardiography (2D Echo), and 3-dimensional echocardiography (3D Echo) for left ventricular (LV) function assessment with magnetic resonance imaging (MRI). BACKGR...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jacc.2012.01.046

    authors： Greupner J,Zimmermann E,Grohmann A,Dübel HP,Althoff TF,Borges AC,Rutsch W,Schlattmann P,Hamm B,Dewey M

    更新日期：2012-05-22 00:00:00

  • Improvement of coronary artery endothelial dysfunction with lipid-lowering therapy: heterogeneity of segmental response and correlation with plasma-oxidized low density lipoprotein.

    abstract：OBJECTIVES:This study assessed coronary artery endothelial function in patients with hypercholesterolemia before and after lipid lowering, using quantitative angiography to examine the acetylcholine (Ach) response along the entire analyzable vessel. BACKGROUND:Lipid lowering reverses endothelial dysfunction, but wheth...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)01180-3

    authors： Penny WF,Ben-Yehuda O,Kuroe K,Long J,Bond A,Bhargava V,Peterson JF,McDaniel M,Juliano J,Witztum JL,Ross J Jr,Peterson KL

    更新日期：2001-03-01 00:00:00

  • A comparison of the clinical impact of bleeding measured by two different classifications among patients with acute coronary syndromes.

    abstract：OBJECTIVES:The goal of this study was to determine the association between Thrombolysis In Myocardial Infarction (TIMI) and Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) bleeding and clinical outcomes. BACKGROUND:There are limited data on the relative utility of either scale at predicting clinica...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2005.09.060

    authors： Rao SV,O'Grady K,Pieper KS,Granger CB,Newby LK,Mahaffey KW,Moliterno DJ,Lincoff AM,Armstrong PW,Van de Werf F,Califf RM,Harrington RA

    更新日期：2006-02-21 00:00:00

  • Homocysteine hypothesis for atherothrombotic cardiovascular disease: not validated.

    abstract：:Homocysteine has been implicated in promoting atherosclerotic and thrombotic vascular disease. During the last decade, the utility of homocysteine in predicting risk for atherothrombotic vascular disease has been evaluated in several observational studies in a large number of patients. These studies show that the over...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2006.04.086

    authors： Kaul S,Zadeh AA,Shah PK

    更新日期：2006-09-05 00:00:00

  • The warm-up effect protects against ischemic left ventricular dysfunction in patients with angina.

    abstract：OBJECTIVES:The goal of this study was to investigate whether the "warm-up" effect in angina protects against ischemic left ventricular (LV) dysfunction. BACKGROUND:After exercise, patients with coronary disease demonstrate persistent myocardial dysfunction, which may represent stunning, as well as warm-up protection a...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)01182-7

    authors： Kelion AD,Webb TP,Gardner MA,Ormerod OJ,Banning AP

    更新日期：2001-03-01 00:00:00

  • Obesity: Pathophysiology and Management.

    abstract：:Obesity continues to be among the top health concerns across the globe. Despite our failure to contain the high prevalence of obesity, we now have a better understanding of its pathophysiology, and how excess adiposity leads to type 2 diabetes, hypertension, and cardiovascular disease. Lifestyle modification is recomm...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2017.11.011

    authors： Gadde KM,Martin CK,Berthoud HR,Heymsfield SB

    更新日期：2018-01-02 00:00:00

  • Reflex control of coronary vascular tone by cardiopulmonary receptors in humans.

    abstract：:To examine whether cardiopulmonary receptors participate in the reflex control of coronary vascular resistance, systemic and coronary hemodynamics were assessed before and during -10 mm Hg lower body negative pressure in eight normal subjects and eight hypertensive patients with left ventricular hypertrophy. In both s...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)90050-x

    authors： Trimarco B,Vigorito C,Cuocolo A,Ricciardelli B,De Luca N,Volpe M,Lembo G,Condorelli M

    更新日期：1988-05-01 00:00:00

  • Repaired coarctation: a "cost-effective" approach to identify complications in adults.

    abstract：OBJECTIVES:The study was done to determine the most "cost-effective" approach to follow adults after repair of coarctation of the aorta. BACKGROUND:Recoarctation and/or aneurysm formation following surgical repair or angioplasty for coarctation of the aorta carry a significant morbidity and mortality. Various screenin...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(99)00653-1

    authors： Therrien J,Thorne SA,Wright A,Kilner PJ,Somerville J

    更新日期：2000-03-15 00:00:00

  • The neonatal heart has a relatively high content of total collagen and type I collagen, a condition that may explain the less compliant state.

    abstract：OBJECTIVES:This study evaluated the extent of the collagen network in neonatal heart muscle and whether the type I/type III collagen ratio is the same as in the adult heart. BACKGROUND:The functional integrity and the stress-strain relation of heart muscle depends largely on the extracellular collagen matrix. The ques...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90612-2

    authors： Marijianowski MM,van der Loos CM,Mohrschladt MF,Becker AE

    更新日期：1994-04-01 00:00:00

  • Colchicine for prevention of early atrial fibrillation recurrence after pulmonary vein isolation: a randomized controlled study.

    abstract：OBJECTIVES:The purpose of the present study was to test the potential of colchicine, an agent with potent anti-inflammatory action, to reduce atrial fibrillation (AF) recurrence after pulmonary vein isolation in patients with paroxysmal AF. BACKGROUND:Proinflammatory processes induced by AF ablation therapy have been ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2012.07.031

    authors： Deftereos S,Giannopoulos G,Kossyvakis C,Efremidis M,Panagopoulou V,Kaoukis A,Raisakis K,Bouras G,Angelidis C,Theodorakis A,Driva M,Doudoumis K,Pyrgakis V,Stefanadis C

    更新日期：2012-10-30 00:00:00

  • Low density lipoprotein cholesterol and coronary microvascular dysfunction in hypercholesterolemia.

    abstract：OBJECTIVES:The present study evaluates the impact of total cholesterol (TC) and its subfractions on coronary flow reserve (CFR), an index of the integrated function of the coronary circulation, in asymptomatic subjects. BACKGROUND:Endothelial dysfunction of the coronary microcirculation has been reported in asymptomat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)00697-5

    authors： Kaufmann PA,Gnecchi-Ruscone T,Schäfers KP,Lüscher TF,Camici PG

    更新日期：2000-07-01 00:00:00

  • Serial changes in regional right ventricular free wall and left ventricular septal wall lengths during the first 4 to 5 years after index anterior wall myocardial infarction.

    abstract：OBJECTIVES:This study investigated serial changes in regional right ventricular free wall and interventricular septal wall lengths during the first 4 to 5 years after an index anterior wall myocardial infarction. BACKGROUND:We previously demonstrated that remodeling after anterior wall myocardial infarction was a bive...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)80012-6

    authors： Hirose K,Reed JE,Rumberger JA

    更新日期：1995-08-01 00:00:00

  • Experimental validation of circumferential, longitudinal, and radial 2-dimensional strain during dobutamine stress echocardiography in ischemic conditions.

    abstract：OBJECTIVES:The aim of this study was to assess and validate 2-dimensional (2D) strain for the detection of ischemia during dobutamine stress echocardiography (DSE). BACKGROUND:Evaluation of abnormalities of left ventricular (LV) function from wall thickening during DSE is unsatisfactory and requires a high level of ex...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2007.07.088

    authors： Reant P,Labrousse L,Lafitte S,Bordachar P,Pillois X,Tariosse L,Bonoron-Adele S,Padois P,Deville C,Roudaut R,Dos Santos P

    更新日期：2008-01-15 00:00:00