Abstract:
:Thirty patients with stable exertional angina undergoing percutaneous transluminal coronary angioplasty of an isolated obstructive lesion of the proximal left anterior descending artery were prospectively evaluated to investigate the relation between angina induced by balloon inflation and the quantity and severity of myocardial ischemia as determined by electrocardiographic (ECG) monitoring and by echocardiographic assessment of regional and global left ventricular wall motion. Anginal pain interviews, continuous two-dimensional echocardiographic recordings and 12 lead ECG recordings at 10 second intervals were obtained for the first two inflation sequences. Seventeen patients had angina with both inflations (symptomatic group), seven patients had no angina or related symptoms during either inflation (asymptomatic group) and six patients had both painful and painless inflations (mixed response group). Comparison of the three groups revealed that they did not differ in mean age, sex distribution, prior history of angina or the incidence of comorbid conditions. Echocardiographic measurements of global and regional left ventricular dysfunction during balloon inflation were comparable in the symptomatic and asymptomatic groups. Similarly, there were no significant differences in the time to onset or magnitude of ST segment changes. The results of the wall motion and ECG studies in the mixed response group paralleled the results in the symptomatic and asymptomatic groups, with no significant differences in any of the variables measured between the painful and painless inflations. These data demonstrate that silent myocardial ischemia occurs in an appreciable proportion of patients during coronary angioplasty and the absence of angina does not imply that a lesser amount of myocardium is jeopardized than with painful inflations.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Wohlgelernter D,Jaffe CC,Cabin HS,Yeatman LA Jr,Cleman Mdoi
10.1016/s0735-1097(87)80189-4subject
Has Abstractpub_date
1987-09-01 00:00:00pages
491-8issue
3eissn
0735-1097issn
1558-3597pii
S0735-1097(87)80189-4journal_volume
10pub_type
杂志文章abstract::Cardiac resynchronization therapy (CRT) is used to treat a subset of heart failure patients with discoordinate wall motion. Defining appropriate patients is important, and, although electrical delay (wide QRS) is commonly used, recent data show that measures of mechanical dyssynchrony improve the sensitivity and speci...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the effect of PCSK9 R46L on low-density lipoprotein cholesterol (LDL-C), risk of ischemic heart disease (IHD), and mortality. BACKGROUND:The 46L allele has been associated with reductions in LDL-C and risk of IHD, but results vary between studies. METHODS:We determined ...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,meta分析,评审
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更新日期:2010-06-22 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jacc.2005.05.053
更新日期:2005-09-06 00:00:00
abstract:OBJECTIVES:We evaluated telomerase activity in circulating polymorphonuclear neutrophils (PMN) and in PMN isolated from coronary atherosclerotic plaques by a novel approach. BACKGROUND:Delayed apoptosis of PMN have been demonstrated in unstable angina (UA). These cells have a finite lifespan with low telomerase activi...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2007.08.048
更新日期:2007-12-18 00:00:00
abstract:OBJECTIVES:This study aimed to determine the diagnostic and prognostic value of urinary biomarkers of intrinsic acute kidney injury (AKI) when patients were triaged in the emergency department. BACKGROUND:Intrinsic AKI is associated with nephron injury and results in poor clinical outcomes. Several urinary biomarkers ...
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pub_type: 杂志文章,多中心研究
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更新日期:2012-01-17 00:00:00
abstract::Data are required for a meaningful approach to quality and cost-conscious cardiovascular care. How to identify the types of data available and their sources, advantages and limitations to their use, issues involved in combining data from different sources for decision modeling and some possible solutions are discussed...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(89)90166-6
更新日期:1989-09-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2017-06-27 00:00:00
abstract:OBJECTIVES:We sought to evaluate the mechanisms by which nonsurgical septal reduction therapy (NSRT) reduces left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic obstructive cardiomyopathy (HOCM) both acutely and on a long-term basis. BACKGROUND:NSRT reduces LVOT obstruction in patients with...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(00)01045-7
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:The study sought to determine the effects of lipid-lowering with pravastatin on the systemic fibrinolytic profile and on thrombus formation under dynamic flow conditions. BACKGROUND:Lowering cholesterol (C) decreases clinical events in coronary artery disease (CAD) patients, but an analysis of the effects o...
journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(99)00018-2
更新日期:1999-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2006.08.063
更新日期:2007-02-20 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.jacc.2016.03.599
更新日期:2016-07-19 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0735-1097(97)00237-4
更新日期:1997-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0735-1097(97)00433-6
更新日期:1998-01-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(98)00614-7
更新日期:1999-03-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(99)00597-5
更新日期:2000-03-01 00:00:00
abstract::Fifty patients with anteroapical left ventricular aneurysm secondary to prior myocardial infarction underwent aneurysmectomy, at which time endocardial sinus rhythm mapping was performed. Forty patients had a history of recurrent sustained monomorphic ventricular tachycardia, and 10 had an aneurysm but no history of s...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(88)90409-3
更新日期:1988-08-01 00:00:00
abstract::Cardiac electrophysiologic alterations were evaluated 1 to 8 months after partial supracoronary aortic constriction in cats. This procedure induced left ventricular systolic hypertension and hypertrophy with marked connective tissue infiltration. In situ, premature ventricular complexes were observed during or after v...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(83)80275-7
更新日期:1983-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0735-1097(88)90361-0
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1988-12-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:2008-02-19 00:00:00
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更新日期:1993-05-01 00:00:00
abstract::Sotalol is a beta-adrenergic blocking agent that prolongs the duration of the cardiac action potential in humans, without affecting the upstroke velocity of depolarization. The dextrorotatory isomer, d-sotalol, retains these class III effects, but has little beta-blocking activity in vitro. d-Sotalol has not been stud...
journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1987-07-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1986-09-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2006-11-07 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jacc.2017.07.714
更新日期:2017-08-29 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(95)00369-X
更新日期:1995-12-01 00:00:00
abstract:OBJECTIVES:This study was designed to test the effects of n-3 polyunsaturated fatty acids (PUFAs) on left ventricular (LV) systolic function in chronic heart failure (HF) due to nonischemic dilated cardiomyopathy (NICM). BACKGROUND:One hundred thirty-three patients with NICM and minimal symptoms on standard therapy we...
journal_title:Journal of the American College of Cardiology
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更新日期:2011-02-15 00:00:00
abstract:OBJECTIVES:The aim of this study was to describe usage of the wearable cardioverter-defibrillator (WCD) during mandated waiting periods following myocardial infarction (MI) for patients perceived to be at high risk for sudden cardiac arrest (SCA). BACKGROUND:Current device guidelines and insurance coverage require wai...
journal_title:Journal of the American College of Cardiology
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更新日期:2013-11-19 00:00:00
abstract::The ubiquity of coronary artery disease and the resultant widespread use of saphenous veins for coronary artery bypass surgery has stimulated considerable interest in the morphologic and pathophysiologic alterations these vessels undergo after implantation. This study was undertaken to determine the ability of intrava...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(92)90514-n
更新日期:1992-03-15 00:00:00