Short-Term Exposure to Ambient Air Pollution and Mortality From Myocardial Infarction.


BACKGROUND:Short-term exposure to ambient air pollution has been linked to occurrence of myocardial infarction (MI); however, only a limited number of studies investigated its association with death from MI, and the results remain inconsistent. OBJECTIVES:This study sought to investigate the association of short-term exposure to air pollution across a wide range of concentrations with MI mortality. METHODS:A time-stratified case-crossover study was conducted to investigate 151,608 MI death cases in Hubei province (China) from 2013 to 2018. Based on each case's home address, exposure to particulate matter with an aerodynamic diameter ≤2.5 μm (PM2.5), particulate matter with an aerodynamic diameter ≤10 μm (PM10), sulfur dioxide, nitrogen dioxide (NO2), carbon monoxide, and ozone on each of the case and control days was assessed as the inverse distance-weighted average concentration at neighboring air quality monitoring stations. Conditional logistic regression models were implemented to quantify exposure-response associations. RESULTS:Exposure to PM2.5, PM10, and NO2 (mean exposure on the same day of death and 1 day prior) was significantly associated with increased odds of MI mortality. The odds associated with PM2.5 and PM10 exposures increased steeply before a breakpoint (PM2.5, 33.3 μg/m3; PM10, 57.3 μg/m3) and flattened out at higher exposure levels, while the association for NO2 exposure was almost linear. Each 10-μg/m3 increase in exposure to PM2.5 (<33.3 μg/m3), PM10 (<57.3 μg/m3), and NO2 was significantly associated with a 4.14% (95% confidence interval [CI]: 1.25% to 7.12%), 2.67% (95% CI: 0.80% to 4.57%), and 1.46% (95% CI: 0.76% to 2.17%) increase in odds of MI mortality, respectively. The association between NO2 exposure and MI mortality was significantly stronger in older adults. CONCLUSIONS:Short-term exposure to PM2.5, PM10, and NO2 was associated with increased risk of MI mortality.


J Am Coll Cardiol


Liu Y,Pan J,Fan C,Xu R,Wang Y,Xu C,Xie S,Zhang H,Cui X,Peng Z,Shi C,Zhang Y,Sun H,Zhou Y,Zhang L




Has Abstract


2021-01-26 00:00:00














  • Usefulness of electrophysiologic study to determine the clinical tolerance of arrhythmia recurrences during amiodarone therapy.

    abstract::The relation of clinical and electrophysiologic variables to outcome was evaluated in 121 patients treated with amiodarone for sustained ventricular tachyarrhythmias. Electrophysiologic study was performed in all patients a mean of 14 days after beginning amiodarone therapy. Forty-six patients who were given oral amio...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Kadish AH,Buxton AE,Waxman HL,Flores B,Josephson ME,Marchlinski FE

    更新日期:1987-07-01 00:00:00

  • Right coronary artery-pulmonary artery arteriovenous fistula secondary to open heart surgery.

    abstract::A patient is described who underwent atrial septal defect repair at age 12 and presented 16 years later with angina. Coronary angiography revealed a right coronary artery to pulmonary artery fistula that had developed at the site of the previous thoracotomy. This is the first report of an acquired fistula of this type...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Rothschild AH,Adatepe MH,Magovern GJ,Rothschild MA,Joyner CR

    更新日期:1985-10-01 00:00:00

  • Extent of early ST segment elevation resolution: a strong predictor of outcome in patients with acute myocardial infarction and a sensitive measure to compare thrombolytic regimens. A substudy of the International Joint Efficacy Comparison of Thrombolytic

    abstract:OBJECTIVES:This study was undertaken to assess prospectively the prognostic power of early ST segment elevation resolution in a large cohort of patients with myocardial infarction and to test the value of differences in ST segment resolution as a surrogate end point. BACKGROUND:Previous studies revealed that the use o...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Schröder R,Wegscheider K,Schröder K,Dissmann R,Meyer-Sabellek W

    更新日期:1995-12-01 00:00:00

  • Eicosanoid biosynthesis in patients with stable angina: beneficial effects of very low dose aspirin.

    abstract:OBJECTIVE:We assessed the production of eicosanoids and the effects of very low dose aspirin in patients with stable angina under basal conditions and during rapid atrial pacing. BACKGROUND:Platelet activation occurs in acute ischemic syndromes but is still controversial in stable angina. Very low dose aspirin is know...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章


    authors: Montalescot G,Maclouf J,Drobinski G,Salloum J,Grosgogeat Y,Thomas D

    更新日期:1994-07-01 00:00:00

  • A randomized comparison of paclitaxel-eluting stents versus bare-metal stents for treatment of unprotected left main coronary artery stenosis.

    abstract:OBJECTIVES:To optimize percutaneous coronary intervention (PCI) strategy for unprotected left main (LM) disease, we performed a randomized study: intravascular ultrasound (IVUS)-guided bare-metal stent (BMS) or paclitaxel-eluting stent (PES) implantation after lesion pre-treatment with cutting balloon (CB) for unprotec...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Erglis A,Narbute I,Kumsars I,Jegere S,Mintale I,Zakke I,Strazdins U,Saltups A

    更新日期:2007-08-07 00:00:00

  • Heart rate and blood pressure response to upright tilt in young patients with unexplained syncope.

    abstract::Syncope in apparently normal patients has been attributed to an inhibitory reflex originating in cardiac sensory receptors. The reflex may be elicited by upright tilt with or without isoproterenol infusion. In this study, an upright 90 degree tilt protocol was evaluated in 20 young patients aged 7 to 22 years with syn...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Pongiglione G,Fish FA,Strasburger JF,Benson DW Jr

    更新日期:1990-07-01 00:00:00

  • An epidemic of dyssynchrony: but what does it mean?

    abstract::Cardiac resynchronization therapy (CRT) is used to treat a subset of heart failure patients with discoordinate wall motion. Defining appropriate patients is important, and, although electrical delay (wide QRS) is commonly used, recent data show that measures of mechanical dyssynchrony improve the sensitivity and speci...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审


    authors: Kass DA

    更新日期:2008-01-01 00:00:00

  • Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].

    abstract:OBJECTIVES:The goal of this study was to understand the role of genetic variation in the catecholamine biosynthetic pathway for control of human heart rate (HR). BACKGROUND:Human HR is an integrated cardiovascular trait predictive of morbidity and survival. Because the autonomic pathway exerts rapid control over the h...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Zhang K,Deacon DC,Rao F,Schork AJ,Fung MM,Waalen J,Schork NJ,Nievergelt CM,Chi NC,O'Connor DT

    更新日期:2014-02-04 00:00:00

  • Syncope: therapeutic approaches.

    abstract::Syncope is a common clinical problem characterized by transient, spontaneously self-terminating loss of consciousness with complete and prompt recovery; the cause is insufficiency of cerebral oxygen/nutrient supply most often due to a transient fall of systemic arterial pressure to levels below those tolerated by cere...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审


    authors: Benditt DG,Nguyen JT

    更新日期:2009-05-12 00:00:00

  • Reprint of: Cardiovascular Disease Prevention by Diet Modification: JACC Health Promotion Series.

    abstract::Reduction in excess calories and improvement in dietary composition may prevent many primary and secondary cardiovascular events. Current guidelines recommend diets high in fruits, vegetables, whole grains, nuts, and legumes; moderate in low-fat dairy and seafood; and low in processed meats, sugar-sweetened beverages,...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审


    authors: Yu E,Malik VS,Hu FB

    更新日期:2018-12-11 00:00:00

  • A mutation in CALM1 encoding calmodulin in familial idiopathic ventricular fibrillation in childhood and adolescence.

    abstract:OBJECTIVES:This study aimed to identify the genetic defect in a family with idiopathic ventricular fibrillation (IVF) manifesting in childhood and adolescence. BACKGROUND:Although sudden cardiac death in the young is rare, it frequently presents as the first clinical manifestation of an underlying inherited arrhythmia...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Marsman RF,Barc J,Beekman L,Alders M,Dooijes D,van den Wijngaard A,Ratbi I,Sefiani A,Bhuiyan ZA,Wilde AA,Bezzina CR

    更新日期:2014-01-28 00:00:00

  • Quality of care of and outcomes for African Americans hospitalized with heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry.

    abstract:OBJECTIVES:We sought to examine the characteristics, quality of care, and clinical outcomes for a large cohort of African-American patients hospitalized with heart failure (HF) in centers participating in a quality improvement initiative. BACKGROUND:Heart failure in African Americans is characterized by variations in ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Yancy CW,Abraham WT,Albert NM,Clare R,Stough WG,Gheorghiade M,Greenberg BH,O'Connor CM,She L,Sun JL,Young JB,Fonarow GC

    更新日期:2008-04-29 00:00:00

  • Prediction of coronary events with electron beam computed tomography.

    abstract:OBJECTIVES:We sought to determine the prognostic accuracy of electron beam computed tomographic (EBCT) scanning of the coronary arteries at three to four years. BACKGROUND:Coronary artery calcium scores determined by EBCT correlate with the severity of coronary artery disease. However, previous reports of the prognost...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Arad Y,Spadaro LA,Goodman K,Newstein D,Guerci AD

    更新日期:2000-10-01 00:00:00

  • Enteric Coating and Aspirin Nonresponsiveness in Patients With Type 2 Diabetes Mellitus.

    abstract:BACKGROUND:A limitation of aspirin is that some patients, particularly those with diabetes, may not have an optimal antiplatelet effect. OBJECTIVES:The goal of this study was to determine if oral bioavailability mediates nonresponsiveness. METHODS:The rate and extent of serum thromboxane generation and aspirin pharma...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Bhatt DL,Grosser T,Dong JF,Logan D,Jeske W,Angiolillo DJ,Frelinger AL 3rd,Lei L,Liang J,Moore JE,Cryer B,Marathi U

    更新日期:2017-02-14 00:00:00

  • State Requirements for Automated External Defibrillators in American Schools: Framing the Debate About Legislative Action.

    abstract::Installation of automated external defibrillators (AEDs) in schools has been associated with increased survival after sudden cardiac arrest. An authoritative academic research database was interrogated to identify all current state statutes pertaining to AEDs in schools. As of February 2016, 17 of 50 U.S. states (34%)...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审


    authors: Sherrid MV,Aagaard P,Serrato S,Arabadjian ME,Lium JM,Lium JD,Greenberg HM

    更新日期:2017-04-04 00:00:00

  • First-pass nuclear magnetic resonance imaging studies using gadolinium-DTPA in patients with coronary artery disease.

    abstract::Nuclear magnetic resonance (NMR) imaging has been shown to accurately portray cardiac anatomy and function. To investigate the potential of NMR imaging for the assessment of coronary stenosis in patients with chest pain, ultrafast NMR imaging in conjunction with a T1 (longitudinal relaxation time) contrast agent was p...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Manning WJ,Atkinson DJ,Grossman W,Paulin S,Edelman RR

    更新日期:1991-10-01 00:00:00

  • Long-term outcome in patients with Marfan syndrome: is aortic dissection the only cause of sudden death?

    abstract:OBJECTIVES:We sought to assess outcomes in a series of young patients with Marfan syndrome and to define the prevalence of ventricular arrhythmias in this patient population. BACKGROUND:While sudden death is a well-recognized outcome in Marfan syndrome, ventricular arrhythmias are not well described. METHODS:Patients...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Yetman AT,Bornemeier RA,McCrindle BW

    更新日期:2003-01-15 00:00:00

  • Does the rest electrocardiogram after myocardial infarction determine the predictive value of exercise-induced ST depression? A 2 year follow-up study in a veteran population.

    abstract::The failure of exercise-induced ST segment depression to consistently predict prognosis in patients after myocardial infarction could be a result of population differences and the rest electrocardiogram (ECG). These hypotheses were tested by studying 198 veterans who survived a myocardial infarction, underwent a subma...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Klein J,Froelicher VF,Detrano R,Dubach P,Yen R

    更新日期:1989-08-01 00:00:00

  • Lymphatic drainage from the ventricular septum to the atrioventricular node in human beings.

    abstract::It has been suggested that intracardiac lymphatics may play a role in the pathophysiologic processes involving the conduction system. To test the possibility of linkage between the ventricular septum and the atrioventricular (AV) node, india ink was injected into the ventricular septum of freshly removed human hearts....

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Uhley HN,Leeds SE,Sung MA

    更新日期:1983-04-01 00:00:00

  • Acute occlusion in multiple lesion coronary angioplasty: frequency and management.

    abstract::Among 3,548 patients undergoing a percutaneous transluminal coronary angioplasty procedure, 714 had multilesion angioplasty (1,550 lesions) in a single session. Acute occlusion occurred in 22 patients (3.1%) and 29 lesions (1.9%). The patients were classified into a group undergoing multivessel angioplasty (348 patien...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Gaul G,Hollman J,Simpfendorfer C,Franco I

    更新日期:1989-02-01 00:00:00

  • Implications of small reference vessel diameter in patients undergoing percutaneous coronary revascularization.

    abstract:OBJECTIVES:The purpose of this study was to determine whether small reference diameter of the culprit coronary artery influences the outcome of an attempted percutaneous revascularization procedure in the current era of interventional cardiology. BACKGROUND:Although the interventional strategy is largely determined by...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Schunkert H,Harrell L,Palacios IF

    更新日期:1999-07-01 00:00:00

  • Long-term angiographic and clinical outcome after implantation of a balloon-expandable stent in the native coronary circulation. Palmaz-Schatz Stent Study Group.

    abstract:OBJECTIVES:The purpose of this study was to examine the long-term clinical and angiographic outcome after coronary stent implantation. BACKGROUND:Previous reports have shown a discordance between the excellent initial angiographic results and subsequent adverse clinical events after coronary artery stenting. METHODS:...

    journal_title:Journal of the American College of Cardiology

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    authors: Savage MP,Fischman DL,Schatz RA,Teirstein PS,Leon MB,Baim D,Ellis SG,Topol EJ,Hirshfeld JW,Cleman MW

    更新日期:1994-11-01 00:00:00

  • Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine.

    abstract::Members of the vascular endothelial growth factor (VEGF) family are among the most powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and vascular maintenance during embryogenesis and in adults. Because of their profound effects on blood vessels, VEGFs have received much attention reg...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审


    authors: Ylä-Herttuala S,Rissanen TT,Vajanto I,Hartikainen J

    更新日期:2007-03-13 00:00:00

  • Nicotine inhibits cardiac apoptosis induced by lipopolysaccharide in rats.

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    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Suzuki J,Bayna E,Dalle Molle E,Lew WY

    更新日期:2003-02-05 00:00:00

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    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Cohen DJ,Breall JA,Ho KK,Weintraub RM,Kuntz RE,Weinstein MC,Baim DS

    更新日期:1993-10-01 00:00:00

  • Provocation of neurocardiogenic syncope by clomipramine administration during the head-up tilt test in vasovagal syndrome.

    abstract:OBJECTIVES:We sought to test the hypothesis that activation of the serotonergic system in patients with vasovagal syndrome during the head-up tilt test provokes syncope. BACKGROUND:Central serotonergic activation participates in the pathogenesis of neurocardiogenic syncope. Drugs increasing serotonin (5-HT) in the cen...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Theodorakis GN,Markianos M,Zarvalis E,Livanis EG,Flevari P,Kremastinos DT

    更新日期:2000-07-01 00:00:00

  • Plasma dehydroepiandrosterone and dehydroepiandrosterone sulfate in patients undergoing diagnostic coronary angiography.

    abstract::Serum levels of DHEA sulfate are inversely associated with cardiovascular death in men, and urinary dehydroepiandrosterone (DHEA) levels are inversely associated with clinical manifestations of coronary artery disease. These observations may be related to the antiproliferative effects of DHEA, resulting in inhibition ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 更正并重新发布的文章,杂志文章


    authors: Herrington DM,Gordon GB,Achuff SC,Trejo JF,Weisman HF,Kwiterovich PO Jr,Pearson TA

    更新日期:1990-11-01 00:00:00

  • The implanted defibrillator: relation of defibrillating lead configuration and clinical variables to defibrillation threshold.

    abstract::Forty-two defibrillating lead systems for the automatic implantable defibrillator were implanted and tested in 41 patients. Two basic lead configurations were used: 1) spring-patch, consisting of a transvenous superior vena cava spring electrode as the anode and an apical or left lateral ventricular patch electrode (e...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Troup PJ,Chapman PD,Olinger GN,Kleinman LH

    更新日期:1985-12-01 00:00:00

  • Radial versus femoral randomized investigation in ST-segment elevation acute coronary syndrome: the RIFLE-STEACS (Radial Versus Femoral Randomized Investigation in ST-Elevation Acute Coronary Syndrome) study.

    abstract:OBJECTIVES:The purpose of this study was to assess whether transradial access for ST-segment elevation acute coronary syndrome undergoing early invasive treatment is associated with better outcome compared with conventional transfemoral access. BACKGROUND:In patients with acute coronary syndrome, bleeding is a signifi...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Romagnoli E,Biondi-Zoccai G,Sciahbasi A,Politi L,Rigattieri S,Pendenza G,Summaria F,Patrizi R,Borghi A,Di Russo C,Moretti C,Agostoni P,Loschiavo P,Lioy E,Sheiban I,Sangiorgi G

    更新日期:2012-12-18 00:00:00

  • Intravascular ultrasound study of angiographically mildly diseased coronary arteries.

    abstract:OBJECTIVES:We hypothesized that intravascular ultrasound may identify significant coronary artery narrowing in the mildly diseased coronary artery of patients with insignificant or one- or two-vessel coronary artery disease. BACKGROUND:Necropsy studies have revealed that coronary angiography may underestimate stenosis...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章


    authors: Porter TR,Sears T,Xie F,Michels A,Mata J,Welsh D,Shurmur S

    更新日期:1993-12-01 00:00:00