Two innovative pharmaceutical forms of leuprorelin: results from 818 patients with advanced prostate cancer.

abstract：:This study was performed to investigate the relationships between markers of inflammation in serum (interleukin-6 [IL-6], interleukin-10 [IL-10], and granulocyte elastase [GE]), severity of injury, and clinical outcomes, and to evaluate the predictive value of these markers for major complications and mortality. This ...

journal_title：Advances in therapy

authors： Akkose S,Ozgurer A,Bulut M,Koksal O,Ozdemír F,Ozguç H

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Evidence suggests that elevated plasma levels of B-type natriuretic peptide (BNP) are found in patients with chronic obstructive pulmonary disease (COPD) and right ventricular dysfunction. We examined the effects of exercise on plasma BNP levels in patients with COPD who have normal right ventricular funct...

journal_title：Advances in therapy

authors： Gemici G,Erdim R,Celiker A,Tokay S,Ones T,Inanir S,Oktay A

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Diuretic responsiveness in patients with chronic heart failure (CHF) is better assessed by urine production per unit diuretic dose than by the absolute urine output or diuretic dose. Diuretic resistance arises over time when the plateau rate of sodium and water excretion is reached prior to optimal fluid e...

journal_title：Advances in therapy

authors： Paterna S,Di Gaudio F,La Rocca V,Balistreri F,Greco M,Torres D,Lupo U,Rizzo G,di Pasquale P,Indelicato S,Cuttitta F,Butler J,Parrinello G

更新日期：2015-10-01 00:00:00

abstract：:X-linked hypophosphataemia (XLH) is the most prevalent form of hereditary rickets characterized by an alteration of phosphate metabolism which frequently leads to the appearance of fractures, bone deformities and growth delay. Although the mechanism of growth impairment in patients with XLH still needs to be clarified...

journal_title：Advances in therapy

authors： Santos Rodríguez F

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Secukinumab, a fully human monoclonal antibody that directly inhibits interleukin-17A, has demonstrated robust efficacy in the treatment of moderate to severe psoriasis (PsO), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), with a rapid onset of action, sustained long-term clinical responses and...

journal_title：Advances in therapy

authors： Kiltz U,Sfikakis PP,Gaffney K,Sator PG,von Kiedrowski R,Bounas A,Gullick N,Conrad C,Rigopoulos D,Lespessailles E,Romanelli M,Ghislain PD,Brandt-Jürgens J,Rashkov R,Aassi M,Orsenigo R,Perella C,Pournara E,Gathmann S,

更新日期：2020-06-01 00:00:00

abstract：:In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers. Durable responses and long-term survival benefit has been experienced by many cancer patients, with favorable toxicity profiles of immunotherapeutic agents relati...

journal_title：Advances in therapy

authors： Arora S,Velichinskii R,Lesh RW,Ali U,Kubiak M,Bansal P,Borghaei H,Edelman MJ,Boumber Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:To evaluate the retinal function and the relative neural conduction along the visual pathway after treatment with citicoline in liposomal formulation (CLF) eye drops in patients with open angle glaucoma (OAG). METHODS:Twelve OAG patients (mean age ± standard deviation 52.58 ± 11.39 years, intraocular pres...

journal_title：Advances in therapy

authors： Parisi V,Oddone F,Roberti G,Tanga L,Carnevale C,Ziccardi L,Manni G

更新日期：2019-04-01 00:00:00

abstract：:Cardiovascular diseases (CVDs) are the leading cause of premature deaths globally and in Ukraine. Dyslipidemia is a recognized risk factor for the development of CVD. Therefore, early detection and appropriate management of dyslipidemia are essential for the primary prevention of CVDs. However, currently, there is a l...

journal_title：Advances in therapy

authors： Dolzhenko MM,Barnett OY,Grassos C,Dragomiretska NV,Goloborodko BI,Ilashchuk TO,Zuiev KO,Karpenko OV,Kolesnikova OV,Kolesnyk TV,Talaieva TV,Vakaliuk IP,Tiabut TD,Mesnikova IL,Zinych OV

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Type 2 diabetes mellitus (T2DM) is a complex disease in which multiple organs and hormones contribute to the pathogenesis of disease. The intestinal hormone, glucagon-like peptide-1 (GLP-1), secreted in response to nutrient ingestion, increases insulin secretion from pancreatic β-cells and reduces glucagon...

journal_title：Advances in therapy

authors： Jain R

更新日期：2015-11-01 00:00:00

abstract：:There has been increased interest in gout in both academic and clinical practice settings. Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in the last decades in developed countries and therefore the burden of gout has increased. The association of hyperuricemia and gout with ...

journal_title：Advances in therapy

authors： Perez-Ruiz F,Dalbeth N,Bardin T

更新日期：2015-01-01 00:00:00

abstract：:Bacterial translocation is the passage of bacteria or endotoxins from the gastrointestinal tract to extraintestinal sites, such as mesenteric lymph nodes, liver, spleen, and bloodstream. In this study, the investigators examined the effects of various enteral nutrients on bacterial translocation and intestinal morphol...

journal_title：Advances in therapy

authors： Aydogan A,Kismet K,Kilicoglu B,Erel S,Ozcan AH,Gollu A,Yildiz E,Akkus MA

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Claims data (IBM MarketScan Commercial and MarketScan Medicare Supplemental databases) from June 30, 2011 to September 30, 2017 were used to evaluate the cost impact of human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) in this retrospective cohort study. METHODS:The p...

journal_title：Advances in therapy

authors： Sussell JA,Sheinson D,Wu N,Shah-Manek B,Seetasith A

更新日期：2020-04-01 00:00:00

abstract：:Coronary heart disease is the major cause of morbidity and mortality in industrialized countries, and its prevalence is predicted to grow as the population ages. Current drugs for chronic stable angina (such as beta-blockers, calcium-channel blockers, long- and short-acting nitrates, and potassium-channel activators) ...

journal_title：Advances in therapy

authors： Prasad UK,Gray D,Purcell H

更新日期：2009-02-01 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:D-Dimer (DD) has been described as a useful predictor of both morphologic changes in acute thoracic aortic dissection (TAD) and of TAD-associated mortality. This study analyzed the use of DD screening to screen patients with chest pain for acute (TAD) to determine if it improves diagnosis and cost effectiv...

journal_title：Advances in therapy

authors： Moysidis T,Lohmann M,Lutkewitz S,Kemmeries G,Kröger K

更新日期：2011-11-01 00:00:00

abstract：:In an open-label 12-week study, the safety and efficacy of bimatoprost 0.03% was evaluated in 55 patients with open-angle glaucoma or ocular hypertension inadequately controlled by topical beta-blocker monotherapy. Patients discontinued their topical beta-blocker therapy at the baseline visit and began bimatoprost mon...

journal_title：Advances in therapy

authors： Quinones R,Earl ML

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:It is hypothesized that diabetes mellitus (DM) and mood disorders share points of pathophysiological commonality in the central nervous system. METHODS:A PubMed search of all English-language articles published between 1966 and March 2009 was performed with the following search terms: depression, mood disor...

journal_title：Advances in therapy

authors： McIntyre RS,Kenna HA,Nguyen HT,Law CW,Sultan F,Woldeyohannes HO,Adams AK,Cheng JS,Lourenco M,Kennedy SH,Rasgon NL

更新日期：2010-02-01 00:00:00

abstract：:Blood pressure lowering by all classes of antihypertensive drugs is accompanied by significant reductions of stroke and major cardiovascular (CV) events. Drugs acting on the renin-angiotensin-aldosterone system, such as angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), showed s...

journal_title：Advances in therapy

authors： Omboni S,Volpe M

更新日期：2019-02-01 00:00:00

abstract：:Clarithromycin, an advanced-generation macrolide antibiotic, has demonstrated excellent in vitro activity against group A beta-hemolytic streptococcus (GABHS). Potent activity against Streptococcus pyogenes and a favorable pharmacokinetic profile have made it a reasonable alternative for treatment of patients with str...

journal_title：Advances in therapy

authors： McCarty J,Hedrick JA,Gooch WM

更新日期：2000-01-01 00:00:00

abstract：:The tolerability of brimonidine tartrate 0.15%--referred to as bromonidine-Purite 0.15% in this study--was compared with brimonidine tartrate 0.2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover stu...

journal_title：Advances in therapy

authors： Mundorf T,Wilcox KA,Ousler GW 3rd,Welch D,Abelson MB

更新日期：2003-11-01 00:00:00

abstract：INTRODUCTION:It is unclear whether patients and their loved ones appreciate that cardiovascular disease (CVD) is the major cause of morbidity and mortality in type 2 diabetes mellitus (T2DM). The purpose of this survey was to evaluate the degree of awareness regarding the link between T2DM and CVD. METHODS:An online s...

journal_title：Advances in therapy

authors： Perreault L,Boardman MK,Pak J

更新日期：2019-03-01 00:00:00

abstract：:The article "Sleep Quality and Congestion with Breathe Right Nasal Strips: Two Randomized Controlled Trials", written by Michael J. Noss, Renee Ciesla, and Gilbert Shanga, was originally published electronically on the publisher's internet portal (currently SpringerLink) on June 17, 2019 without Open Access. The artic...

journal_title：Advances in therapy

authors： Noss MJ,Ciesla R,Shanga G

更新日期：2019-11-01 00:00:00

abstract：:As head and neck squamous cell carcinoma (HNSCC) patients with distant metastases (DM) were generally treated only palliatively, the value of screening for DM was usually limited to attempts to avoid extensive locoregional treatment when DM were present pretreatment. Recently, the concept of treating oligometastases, ...

journal_title：Advances in therapy

authors： de Bree R,Senft A,Coca-Pelaz A,Kowalski L,Lopez F,Mendenhall W,Quer M,Rinaldo A,Shaha AR,Strojan P,Takes RP,Silver CE,Leemans CR,Ferlito A

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Liraglutide has been widely used in the treatment of type 2 diabetes mellitus (T2DM), however, the results of a number of randomized placebo-controlled trials on the effects of liraglutide for the treatment of T2DM have varied. The purpose of this study was to assess the effects of liraglutide versus place...

journal_title：Advances in therapy

authors： Du Q,Wang YJ,Yang S,Zhao YY,Han P

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess the efficacy and safety of esomeprazole 40 mg once daily (q.d.) in healing reflux oesophagitis at 4 and 8 weeks, and the efficacy of esomeprazole 20 mg q.d. for 12 weeks in the maintenance of remission. METHODS:A total of 235 patients with endoscopically proven reflux o...

journal_title：Advances in therapy

authors： Atug O,Giral A,Kalayci C,Dolar E,Isitan F,Oguz D,Ovunc O,Ozgur O,Soykan I,Simsek I,Unal S,Yenice N,Turkish HEMANEX Study Group.

更新日期：2008-06-01 00:00:00

abstract：:Recently, high levels of neurotrophic factors have been found in bronchial asthma; these factors include nerve growth factor, brain-derived neurotrophic factor, and leukemia inhibitory factor, among others. Neurotrophic factors are first synthesized in bronchial epithelial cells, immune cells, and other cells in the a...

journal_title：Advances in therapy

authors： Feng JT,Hu CP,Li XZ

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS:This study considers demographic, clinical, and...

journal_title：Advances in therapy

authors： Hall LL,Xu L,Mahmud SM,Puckrein GA,Thommes EW,Chit A

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Repository corticotropin injection (RCI; H.P. Acthar® Gel; Mallinckrodt Pharmaceuticals Inc., Hampton, NJ) is a highly purified, prolonged-release porcine preparation of adrenocorticotropic hormone (ACTH) analogue that is FDA-approved for treatment of 19 autoimmune and inflammatory disorders. The diverse p...

journal_title：Advances in therapy

authors： Philbin M,Niewoehner J,Wan GJ

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:Diabetes-related healthcare costs are increasing in the United States, with inpatient hospitalization the largest component of medical expenditures. The aims of this study were to characterize hospitalized type 2 diabetes mellitus (T2DM) patients, understand the relationship between hospitalization and hea...

journal_title：Advances in therapy

authors： Saundankar V,Ellis J,Allen E,DeLuzio T,Moretz C,Meah Y,Suehs B,Bouchard J

更新日期：2015-07-01 00:00:00