当前位置： SCI文献检索 > ADVANCES IN THERAPY期刊下所有文献 > Angiotensin Receptor Blockers Versus Angiotensin Converting Enzyme Inhibitors for the Treatment of Arterial Hypertension and the Role of Olmesartan.

Angiotensin Receptor Blockers Versus Angiotensin Converting Enzyme Inhibitors for the Treatment of Arterial Hypertension and the Role of Olmesartan.

Abstract：

:Blood pressure lowering by all classes of antihypertensive drugs is accompanied by significant reductions of stroke and major cardiovascular (CV) events. Drugs acting on the renin-angiotensin-aldosterone system, such as angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), showed similar benefit on major CV events to other antihypertensive medications. In real-world practice, ARBs reduced by 10% the incidence of CV mortality, non-fatal myocardial infarction, non-fatal stroke and provided superior protection against CV events than ACEIs in high-risk patients. Despite similar antihypertensive properties and a favourable safety profile for both ACEIs and ARBs, evidence indicates that patients treated with ARBs have lower rates of withdrawal for adverse events and greater persistence to therapy than those treated with ACEIs. Among ARBs, olmesartan is one of the latest generation compounds introduced in clinical practice for treating hypertension: head-to-head comparative trials suggest that the efficacy of olmesartan is superior to that of commonly prescribed ACEIs (ramipril and perindopril). The drug, administered as a monotherapy or in combination with a dihydropyridine calcium channel blocker or a thiazide diuretic, has proved to be effective in maintaining blood pressure stability over 24 h, with a favourable safety profile and low discontinuation rates. These properties are pivotal for considering olmesartan as a useful antihypertensive agent especially for high-risk patients (e.g. elderly, diabetics, patients with metabolic syndrome).Funding: Article preparation and open access fee were funded by Menarini International Operations Luxembourg S.A. (M.I.O.L.).

journal_name

Adv Ther

journal_title

Advances in therapy

authors

Omboni S,Volpe M

doi

10.1007/s12325-018-0859-x

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

278-297

issue

2

eissn

0741-238X

issn

1865-8652

pii

10.1007/s12325-018-0859-x

journal_volume

36

pub_type

杂志文章,评审

相关文献

ADVANCES IN THERAPY文献大全
  • Retrospective estimate of the nursing cost of autonomy impairment and cost benefit in clinical trials: feasibility and application of piracetam in demented elderly patients.

    abstract：:The aims of this study were to determine whether the nursing costs of functional disability could be assessed retrospectively and, if so, whether this method was sensitive enough to show the influence of a treatment on economic costs. Four studies were available for this purpose: three randomized, double-blind, place...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：

    authors： Vlietinck R,Van Loon H,Van de Broele H,Tormans G

    更新日期：1993-09-01 00:00:00

  • Clarithromycin suspension vs penicillin V suspension in children with streptococcal pharyngitis.

    abstract：:Clarithromycin, an advanced-generation macrolide antibiotic, has demonstrated excellent in vitro activity against group A beta-hemolytic streptococcus (GABHS). Potent activity against Streptococcus pyogenes and a favorable pharmacokinetic profile have made it a reasonable alternative for treatment of patients with str...

    journal_title：Advances in therapy

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1007/BF02868027

    authors： McCarty J,Hedrick JA,Gooch WM

    更新日期：2000-01-01 00:00:00

  • The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder.

    abstract：INTRODUCTION:Ample evidence suggested a role of sigma-1 receptor in affective disorders since the interaction of numerous antidepressants with sigma receptors was discovered. A recent study on Japanese subjects found a genetic variant within the encoding gene SIGMAR1 (rs1800866A>C) associated with major depressive diso...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-017-0482-2

    authors： Mandelli L,Wang SM,Han C,Lee SJ,Patkar AA,Masand PS,Pae CU,Serretti A

    更新日期：2017-03-01 00:00:00

  • Cutaneous manifestations in brucellosis: a prospective study.

    abstract：:Brucellosis remains an important public health problem in Turkey, just as it is in other regions of the world. This study was conducted to determine the types and rates of cutaneous lesions that occur in patients with brucellosis. Brucellosis was diagnosed by standard tube agglutination testing for Brucella antibodies...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/BF02849964

    authors： Akcali C,Savas L,Baba M,Turunc T,Seckin D

    更新日期：2007-07-01 00:00:00

  • Mifepristone treatment of olanzapine-induced weight gain in healthy men.

    abstract：INTRODUCTION:Antipsychotic medications are associated with significant weight gain, type 2 diabetes mellitus, dyslipidemia, and increased cardiovascular risk. Suggested mechanisms of weight gain from antipsychotic medication include antagonism of histamine and serotonin receptors, and effects on the hypothalamic-pituit...

    journal_title：Advances in therapy

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s12325-009-0070-1

    authors： Gross C,Blasey CM,Roe RL,Allen K,Block TS,Belanoff JK

    更新日期：2009-10-01 00:00:00

  • Attitudes of physiotherapists and physiotherapy students toward euthanasia: a comparative study.

    abstract：:This interventional study was undertaken to assess the impact of physiotherapy education on the knowledge and attitudes of physiotherapists (PTs) and physiotherapy students (PSs) toward euthanasia. The study, which was conducted during the period between 2004 and 2005, included a total of 494 participants (311 PTs; 18...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/BF02850001

    authors： Cavlak U,Aslan UB,Gurso S,Yagci N,Yeldan I

    更新日期：2007-01-01 00:00:00

  • A Longitudinal Study of the Association of Opioid Use with Change in Pain Interference and Functional Limitations in a Nationally Representative Cohort of Adults with Osteoarthritis in the United States.

    abstract：INTRODUCTION:Real-world data are sparse on longitudinal associations of opioid use with pain interference with activities (PIA) and daily function with osteoarthritis (OA) in the USA. METHODS:Data from the 2010-2015 Medical Expenditure Panel Surveys were analyzed for community-dwelling adults with OA. Opioid use patte...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-019-01200-4

    authors： Shah D,Zhao X,Wei W,Gandhi K,Dwibedi N,Webster L,Sambamoorthi U

    更新日期：2020-02-01 00:00:00

  • Efficacy of etanercept and complete decongestive physical therapy in bilateral lower-limb lymphoedema associated with rheumatoid arthritis: a case report.

    abstract：:A 54-y-old patient with rheumatoid arthritis (RA) and bilateral lower-limb lymphoedema is presented. Complete decongestive physical therapy (CDP) is the cornerstone of the management programme in all patients suffering from lymphoedema associated with RA, but it is not clear which therapy is the most effective in decr...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-008-0006-1

    authors： Eyigor S,Karapolat H,Kirazli Y

    更新日期：2008-01-01 00:00:00

  • Postmarketing surveillance study of nateglinide in Japan.

    abstract：:Nateglinide is an oral antidiabetic medication that acts through rapid, short-term stimulation of insulin production. This study was undertaken to identify the incidence and nature of adverse effects of nateglinide and to assess its efficacy in clinical practice. Patients (n = 3254) were recruited from 606 centers in ...

    journal_title：Advances in therapy

    pub_type： 杂志文章,多中心研究

    doi：10.1007/BF02849871

    authors： Taki H,Maki T,Iso T,Iwamoto K,Kajiura T

    更新日期：2005-09-01 00:00:00

  • An Economic Evaluation of Iron Isomaltoside 1000 Versus Ferric Carboxymaltose in Patients with Inflammatory Bowel Disease and Iron Deficiency Anemia in Denmark.

    abstract：INTRODUCTION:The incidence of inflammatory bowel disease (IBD) in Denmark is among the highest in the world, with Crohn's disease and ulcerative colitis occurring at rates of 9.1 and 18.6 per 100,000 person-years respectively in 2010-2013. Anemia is the most prevalent extraintestinal complication of IBD, most commonly ...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-018-0827-5

    authors： Pollock RF,Muduma G

    更新日期：2018-12-01 00:00:00

  • Safety and efficacy of sibutramine in overweight Hispanic patients with hypertension.

    abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

    journal_title：Advances in therapy

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02850257

    authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

    更新日期：2003-03-01 00:00:00

  • A Map of Racial and Ethnic Disparities in Influenza Vaccine Uptake in the Medicare Fee-for-Service Program.

    abstract：INTRODUCTION:Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS:This study considers demographic, clinical, and...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-020-01324-y

    authors： Hall LL,Xu L,Mahmud SM,Puckrein GA,Thommes EW,Chit A

    更新日期：2020-05-01 00:00:00

  • Evaluation of the comfort of Alphagan P compared with Alphagan in irritated eyes.

    abstract：:The tolerability of brimonidine tartrate 0.15%--referred to as bromonidine-Purite 0.15% in this study--was compared with brimonidine tartrate 0.2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover stu...

    journal_title：Advances in therapy

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02849799

    authors： Mundorf T,Wilcox KA,Ousler GW 3rd,Welch D,Abelson MB

    更新日期：2003-11-01 00:00:00

  • A phase 2 study of naproxen submicron particle capsules in patients with post-surgical dental pain.

    abstract：BACKGROUND:Naproxen is an NSAID with documented efficacy in pain management; however, it is associated with serious dose-related adverse events. A lower-dose naproxen drug product with comparable efficacy to commercially available naproxen could address these concerns. We studied the efficacy and safety of naproxen sub...

    journal_title：Advances in therapy

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s12325-013-0057-9

    authors： Young CL,Strand V,Altman R,Daniels S

    更新日期：2013-10-01 00:00:00

  • Meta-Analysis of Regorafenib-Associated Adverse Events and Their Management in Colorectal and Gastrointestinal Stromal Cancers.

    abstract：INTRODUCTION:To assess the risk factors associated with regorafenib-related adverse events (AEs) in metastatic colorectal cancer (mCRC) and gastrointestinal stromal tumors (GIST). We also evaluated different measures of combatting AEs and their success rate to aid physicians in early identification and management of re...

    journal_title：Advances in therapy

    pub_type： 杂志文章,meta分析

    doi：10.1007/s12325-019-01013-5

    authors： Xie G,Gong Y,Wu S,Li C,Yu S,Wang Z,Chen J,Zhao Q,Li J,Liang H

    更新日期：2019-08-01 00:00:00

  • Real-life dosage and clinical efficacy of biphasic insulin preparations in patients with type 2 diabetes.

    abstract：INTRODUCTION:This retrospective study used data from a primary care database to compare two insulin products in routine clinical practice for the treatment of type 2 diabetes in the UK. PATIENTS AND METHODS:Records were analyzed for patients with type 2 diabetes who had been initiated on biphasic insulin aspart 30 (BI...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-010-0079-5

    authors： Fakhoury WK,Richter H,Christensen TE

    更新日期：2010-11-01 00:00:00

  • Safety and tolerability of tapentadol extended release in moderate to severe chronic osteoarthritis or low back pain management: pooled analysis of randomized controlled trials.

    abstract：INTRODUCTION:This analysis of pooled data from four randomized, controlled-dose adjustment, phase 3 studies (three 15-week, double-blind, placebo- and active-controlled studies and a 1-year, open-label, active-controlled safety study) in patients with chronic osteoarthritis hip or knee pain or low back pain evaluated t...

    journal_title：Advances in therapy

    pub_type： 杂志文章,meta分析

    doi：10.1007/s12325-014-0128-6

    authors： Etropolski M,Kuperwasser B,Flügel M,Häufel T,Lange B,Rauschkolb C,Laschewski F

    更新日期：2014-06-01 00:00:00

  • Estimation of the Prevalence of Progressive Fibrosing Interstitial Lung Diseases: Systematic Literature Review and Data from a Physician Survey.

    abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

    journal_title：Advances in therapy

    pub_type： 杂志文章,评审

    doi：10.1007/s12325-020-01578-6

    authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

    更新日期：2020-12-14 00:00:00

  • How Phenotype Guides Management of the Most Common Malignant Salivary Neoplasms of the Larynx?

    abstract：:Salivary gland carcinomas of the larynx are uncommon. Adenoid cystic carcinoma is the most prevalent type of salivary gland carcinoma in this region, although other histologies such as mucoepidermoid carcinoma and adenocarcinomas have been reported. These tumors may present with advanced-stage due to nonspecific sympt...

    journal_title：Advances in therapy

    pub_type： 杂志文章,评审

    doi：10.1007/s12325-017-0494-y

    authors： López F,Williams MD,Skálová A,Hellquist H,Suárez C,Nixon IJ,Rodrigo JP,Cardesa A,Strojan P,Quer M,Hunt JL,Rinaldo A,Ferlito A

    更新日期：2017-04-01 00:00:00

  • Healthcare-Related Costs Associated with Switching Subcutaneous Tumor Necrosis Factor-α Inhibitor in the Treatment of Inflammatory Arthritis: a Retrospective Study.

    abstract：INTRODUCTION:Subsequent lines of subcutaneous tumor necrosis factor alpha inhibitor (SC-TNFi) treatment may be well motivated in the management of rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA)-collectively named inflammatory arthritis (IA). However, the costs associated with swit...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-020-01425-8

    authors： Dalén J,Luttropp K,Svedbom A,Black CM,Kachroo S

    更新日期：2020-09-01 00:00:00

  • Enhancement of Retinal Function and of Neural Conduction Along the Visual Pathway Induced by Treatment with Citicoline Eye Drops in Liposomal Formulation in Open Angle Glaucoma: A Pilot Electrofunctional Study.

    abstract：INTRODUCTION:To evaluate the retinal function and the relative neural conduction along the visual pathway after treatment with citicoline in liposomal formulation (CLF) eye drops in patients with open angle glaucoma (OAG). METHODS:Twelve OAG patients (mean age ± standard deviation 52.58 ± 11.39 years, intraocular pres...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-019-0897-z

    authors： Parisi V,Oddone F,Roberti G,Tanga L,Carnevale C,Ziccardi L,Manni G

    更新日期：2019-04-01 00:00:00

  • Linaclotide, novel therapy for the treatment of chronic idiopathic constipation and constipation-predominant irritable bowel syndrome.

    abstract：:Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the...

    journal_title：Advances in therapy

    pub_type： 杂志文章,评审

    doi：10.1007/s12325-013-0012-9

    authors： Vazquez-Roque MI,Bouras EP

    更新日期：2013-03-01 00:00:00

  • Best Practice Approach to Successful Conversion of Fosaprepitant to Aprepitant IV in a Large Multisite Community Oncology Infusion Center: A Retrospective Analysis.

    abstract：PURPOSE:To evaluate the impact on cost, time, resource use, and clinic workflow of converting the route of drug administration from a neurokinin-1 receptor antagonist (NK-1 RA) 30-min intravenous (IV) infusion to aprepitant IV, and more specifically to IV push, within a multicenter community oncology practice. METHODS...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-020-01377-z

    authors： Burns D,Kula J,Marshall S,Ashworth E,Ornelas M

    更新日期：2020-07-01 00:00:00

  • Structured weight-loss programs: meta-analysis of weight loss at 24 weeks and assessment of effects of intervention intensity.

    abstract：:Obesity is increasing in epidemic proportions globally while current therapies continue to be suboptimal. In this investigation, weight loss in obese individuals after 24 weeks with different nutrition interventions was compared. The impact of intervention intensity was assessed. Inclusion criteria were established an...

    journal_title：Advances in therapy

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/BF02850334

    authors： Anderson JW,Luan J,Høie LH

    更新日期：2004-03-01 00:00:00

  • Metabonomics and diabetes mellitus.

    abstract：:Diabetes mellitus is one of the most serious heterogeneous endocrinologic diseases; more than 90% of those given this diagnosis have type 2 diabetes mellitus, usually accompanied by macrovascular and microvascular complications. Because most cases include a 7- to 10-y latency period before disease onset, however, it i...

    journal_title：Advances in therapy

    pub_type： 杂志文章,评审

    doi：10.1007/BF02877709

    authors： Chen P,Liu J

    更新日期：2007-09-01 00:00:00

  • Totally implantable venous access devices via subclavian vein: a retrospective study of 368 oncology patients.

    abstract：:Totally implantable catheters and totally implantable venous access devices (TIVADs) represent a valid method of administering long-term chemotherapy. TIVADs have several advantages over other methods of venous access: they are easy to implant under local anesthesia, they cause less discomfort for patients, and they c...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/BF02850046

    authors： Ozyuvaci E,Kutlu F

    更新日期：2006-07-01 00:00:00

  • Cost associated with D-Dimer screening for acute aortic dissection.

    abstract：INTRODUCTION:D-Dimer (DD) has been described as a useful predictor of both morphologic changes in acute thoracic aortic dissection (TAD) and of TAD-associated mortality. This study analyzed the use of DD screening to screen patients with chest pain for acute (TAD) to determine if it improves diagnosis and cost effectiv...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-011-0069-2

    authors： Moysidis T,Lohmann M,Lutkewitz S,Kemmeries G,Kröger K

    更新日期：2011-11-01 00:00:00

  • Comparative efficacy of valsartan and olmesartan in mild-to-moderate hypertension: results of 24-hour ambulatory blood pressure monitoring.

    abstract：:The aim of this prospective, randomized, open-label, blinded endpoint (PROBE) study was to compare the antihypertensive efficacy of 2 angiotensin II (AII) receptor antagonists with different pharmacologic profiles, valsartan and olmesartan, in patients with mild-to-moderate essential hypertension. After an initial 2-w...

    journal_title：Advances in therapy

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02850182

    authors： Destro M,Scabrosetti R,Vanasia A,Mugellini A

    更新日期：2005-01-01 00:00:00

  • Long-term allergen-specific immunotherapy correlates with long-term allergen-specific immunological tolerance.

    abstract：INTRODUCTION:One method of treatment for allergic diseases is allergen-specific immunotherapy (SIT). The clinical efficacy of SIT in pollen-induced allergic rhinitis has been demonstrated in several controlled clinical trials. There is no consensus about the protective effect of SIT. In this study, we evaluated the cor...

    journal_title：Advances in therapy

    pub_type： 杂志文章

    doi：10.1007/s12325-008-0004-3

    authors： Ali I,Goksal K,Ozan B,Gulsen D

    更新日期：2008-01-01 00:00:00

  • Correction to: Patterns of Bicalutamide Use in Prostate Cancer Treatment: A U.S. Real-World Analysis Using the SEER-Medicare Database.

    abstract：:The original article can be found online. ...

    journal_title：Advances in therapy

    pub_type： 杂志文章,已发布勘误

    doi：10.1007/s12325-018-0767-0

    authors： Beebe-Dimmer JL,Ruterbusch JJ,Bylsma LC,Gillezeau C,Fryzek J,Schultz NM,Flanders SC,Barlev A,Heath E,Quek RGW

    更新日期：2018-09-01 00:00:00