Management of Dyslipidemia in Individuals with Low-to-Moderate Cardiovascular Risk: Role of Nutraceuticals.

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：INTRODUCTION:Synthesis of evidence on the long-term use of first-line biologic therapy in patients with early rheumatoid arthritis (RA) is required. We compared the efficacy of up to 5 years' treatment with first-line tumor necrosis factor inhibitors (TNFis) versus other treatment strategies in this population. METHOD...

journal_title：Advances in therapy

authors： Gulácsi L,Zrubka Z,Brodszky V,Rencz F,Alten R,Szekanecz Z,Péntek M

更新日期：2019-03-01 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：:The origin of chronic periodontal disease is strongly related to the nature and physiology of the subgingival bacterial biofilm, of which Porphyromonas gingivalis is a main protagonist. This study was conducted in vitro, to test the susceptibility of the W83 strain of P gingivalis to several oral antiseptics, bearing ...

journal_title：Advances in therapy

authors： Bercy P,Lasserre J

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:Tiotropium, a long-acting muscarinic antagonist, is approved for maintenance treatment of asthma in patients at least 6 years of age in the USA. We systematically reviewed published evidence on the efficacy and safety of 2.5 µg tiotropium Respimat® add-on therapy to inhaled corticosteroid (ICS) with or wit...

journal_title：Advances in therapy

authors： Mansfield L,Duong-Quy S,Craig T

更新日期：2019-10-01 00:00:00

abstract：:Duodenal self-expandable metal stents (SEMS) are designed for palliation and prompt relief of malignant gastric outlet obstruction (GOO). This mini-invasive endoscopic treatment is preferable to surgery due to its lower morbidity and mortality, shorter hospitalization, and earlier symptoms relief; furthermore endoscop...

journal_title：Advances in therapy

authors： Boškoski I,Tringali A,Familiari P,Mutignani M,Costamagna G

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of re-education in the insulin injection technique for glycemic control. METHODS:A preliminary experimental study was performed with 87 insulin-treated diabetic outpatients (11 with type 1 diabetes, 76 with type 2 diabetes; 43 men, 44 women). All pat...

journal_title：Advances in therapy

authors： Nakatani Y,Matsumura M,Monden T,Aso Y,Nakamoto T

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:Data regarding the prevalence of immune thrombocytopenia (ITP) is limited, and is derived from North American population-based analyses. Therefore, the authors conducted the first study outside the United States (US) using the United Kingdom (UK) General Practice Research Database (GPRD) to estimate the ad...

journal_title：Advances in therapy

authors： Bennett D,Hodgson ME,Shukla A,Logie JW

更新日期：2011-12-01 00:00:00

abstract：:Dyspnea is the most common symptom experienced by patients with chronic obstructive pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary lifestyle which predictably leads to extensive skeletal muscle deconditioning, social isolation, and its negative psychological sequalae. This "dysp...

journal_title：Advances in therapy

authors： O'Donnell DE,Milne KM,James MD,de Torres JP,Neder JA

更新日期：2020-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF) inhibitors are widely used biologics for the treatment of several chronic inflammatory diseases. The launch of anti-TNF biosimilars has introduced the possibility of non-medical switching between originator biologics and their biosimilars. However, the potential clinical and patient-reporte...

journal_title：Advances in therapy

authors： Numan S,Faccin F

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:The aim of this analysis was to characterize the safety and tolerability of empagliflozin in patients with type 2 diabetes mellitus (T2DM) who were randomized to empagliflozin (10/25 mg) or placebo in clinical trials. METHODS:Pooled data from 20 trials were analyzed for patients with T2DM treated with emp...

journal_title：Advances in therapy

authors： Kinduryte Schorling O,Clark D,Zwiener I,Kaspers S,Lee J,Iliev H

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited. METHODS:We u...

journal_title：Advances in therapy

authors： Olson AL,Maher TM,Acciai V,Mounir B,Quaresma M,Zouad-Lejour L,Wells CD,De Loureiro L

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:The anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI) alectinib was approved in Japan in 2014 for the treatment of ALK fusion gene-positive advanced non-small cell lung cancer (NSCLC). With the approvals of crizotinib in 2012 and ceritinib in 2017, Japan became the first country with multipl...

journal_title：Advances in therapy

authors： Goto Y,Yamamoto N,Masters ET,Kikkawa H,Mardekian J,Wiltshire R,Togo K,Ohe Y

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Intanza® 9 μg (Sanofi Pasteur SA, Lyon, France), a split virion trivalent influenza vaccine delivered by intradermal injection with a microinjection system, became available as a vaccination for adults aged 18 to 59 years old, as of the 2010 southern hemisphere influenza season. METHODS:This study was des...

journal_title：Advances in therapy

authors： Eizenberg P,Booy R,Naser N,Mason G,Stamboulian D,Weber F

更新日期：2011-08-01 00:00:00

abstract：:Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbab...

journal_title：Advances in therapy

authors： Martens MG,Shailer LD

更新日期：1991-05-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which can induce multisystem disease. Human angiotensin-converting enzyme 2 (ACE2) widely expressing in arterial and venous endothelial cells and arterial smooth muscle cells has been identified as a functional rec...

journal_title：Advances in therapy

authors： Wang J,Saguner AM,An J,Ning Y,Yan Y,Li G

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Partial nephrectomy (PN) has evolved into the surgical standard of care for localized renal lesions. Hemostatic agents (HA) support the surgeon in achieving local hemostasis during PN. We previously reported initial results with the HA Hemopatch® in PN. We now report our experiences with Hemopatch® in a la...

journal_title：Advances in therapy

authors： Hupe MC,Büttner M,Tabrizi PF,Merseburger AS,Kuczyk MA,Imkamp F

更新日期：2020-12-04 00:00:00

abstract：INTRODUCTION:The pharmacokinetics, safety, and tolerability of DS-8500a (a G protein receptor 119 agonist) up to 100 mg have been investigated in healthy Japanese adults. The objective of this study was to evaluate the effects of hepatic or renal impairment on the pharmacokinetics of a single 25-mg oral dose of DS-8500...

journal_title：Advances in therapy

authors： Kato M,Ishizuka H,Taguchi T,Shiosakai K,Kamiyama E,Sata M,Yoshida T

更新日期：2018-08-01 00:00:00

abstract：:In this double-blind, randomized, placebo-controlled, prospective study, the clinical efficacy and tolerability of oral Hypericum extract STW 3-VI (Laif) 900 mg once daily was compared with that of placebo. A total of 140 outpatients (94 women; 46 men) with moderate depressive disorders and a 17-item Hamilton Depressi...

journal_title：Advances in therapy

authors： Uebelhack R,Gruenwald J,Graubaum HJ,Busch R

更新日期：2004-07-01 00:00:00

abstract：INTRODUCTION:Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in p...

journal_title：Advances in therapy

authors： Baltzis D,Roustit M,Grammatikopoulou MG,Katsaboukas D,Athanasiou V,Iakovou I,Veves A,Manes C,Trakatelli MC

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:To date, no study has reported the prevalence of cannabis use in chronic pain patients. The aim of this study is to investigate the trends in cannabis use among chronic pain in-patients from 2011 to 2015 in the USA. METHODS:Patients were identified from the National Inpatient Sample (NIS) database using t...

journal_title：Advances in therapy

authors： Orhurhu V,Urits I,Olusunmade M,Olayinka A,Salisu Orhurhu M,Uwandu C,Aner M,Ogunsola S,Akpala L,Hirji S,Viswanath O,Karri J,Simopoulos T,Gill J

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To evaluate the impact on cost, time, resource use, and clinic workflow of converting the route of drug administration from a neurokinin-1 receptor antagonist (NK-1 RA) 30-min intravenous (IV) infusion to aprepitant IV, and more specifically to IV push, within a multicenter community oncology practice. METHODS...

journal_title：Advances in therapy

authors： Burns D,Kula J,Marshall S,Ashworth E,Ornelas M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Phase IV post-marketing surveillance studies are needed to evaluate the real-world safety and effectiveness of drug products. This study aimed to evaluate the safety and effectiveness of biosimilar etanercept (Altebrel, AryoGen Co., Iran) in patients with rheumatoid arthritis (RA), ankylosing spondylitis (...

journal_title：Advances in therapy

authors： Gharibdoost F,Salari AH,Salesi M,Ebrahimi Chaharom F,Mottaghi P,Hosseini M,Sahebari M,Nazarinia M,Mirfeizi Z,Shakibi M,Moussavi H,Karimifar M,Mowla K,Karimzadeh H,Anjidani N,Jamshidi A

更新日期：2021-01-11 00:00:00

abstract：:The tolerability of brimonidine tartrate 0.15%--referred to as bromonidine-Purite 0.15% in this study--was compared with brimonidine tartrate 0.2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover stu...

journal_title：Advances in therapy

authors： Mundorf T,Wilcox KA,Ousler GW 3rd,Welch D,Abelson MB

更新日期：2003-11-01 00:00:00

abstract：INTRODUCTION:The primary analysis of a global phase 3 study that evaluated the efficacy and safety of denosumab versus zoledronic acid for preventing skeletal-related events (SREs) in adults with newly diagnosed multiple myeloma (MM) indicated that denosumab was noninferior to zoledronic acid for time to first on-study...

journal_title：Advances in therapy

authors： Huang SY,Yoon SS,Shimizu K,Chng WJ,Chang CS,Wong RS,Gao S,Wang Y,Gordon SW,Glennane A,Min CK

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Ivabradine has opened up new possibilities for treating stable angina and chronic heart failure by lowering heart rate. Ivabradine lowers heart rate by selectively inhibiting the I f current in the sinoatrial node. This study aimed to determine whether the decrease in heart rate achieved with ivabradine wa...

journal_title：Advances in therapy

authors： Jedlickova L,Merkovska L,Jackova L,Janicko M,Fedacko J,Novakova B,Chmelarova A,Majernik J,Pella D

更新日期：2015-10-01 00:00:00

abstract：:Neuroinflammation is a process involved in the pathogenesis of different disorders, both autoimmune, such as neuropsychiatric systemic lupus erythematosus, and degenerative, such as Alzheimer's and Parkinson's disease. In the central nervous system, the local milieu is tightly regulated by different mediators, among w...

journal_title：Advances in therapy

authors： Gualtierotti R,Guarnaccia L,Beretta M,Navone SE,Campanella R,Riboni L,Rampini P,Marfia G

更新日期：2017-02-01 00:00:00

abstract：:This study was conducted to determine the reasons for the choice of self-prescribed laxatives and to acquire information on how they were used and tolerated. From November 1999 to February 2000, 70 pharmacies, uniformly located throughout the Campania region of southern Italy, distributed a questionnaire to purchasers...

journal_title：Advances in therapy

authors： Motola G,Mazzeo F,Rinaldi B,Capuano A,Rossi S,Russo F,Vitelli MR,Rossi F,Filippelli A

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:To assess the impact of certolizumab pegol (CZP) treatment on clinical, patient-reported, and musculoskeletal ultrasound outcomes and to determine the treatment response time point most predictive of long-term outcomes in Italian patients with rheumatoid arthritis (RA). METHODS:CZP-SPEED (NCT01443364) was...

journal_title：Advances in therapy

authors： Sarzi-Puttini P,Filippucci E,Adami S,Meroni PL,Batticciotto A,Idolazzi L,De Lucia O,Talavera P,Kumke T,Grassi W

更新日期：2018-08-01 00:00:00