Ultrastructural analysis of the Krebs-2 ascites cancer cells treated with extracellular double-stranded DNA preparation.

Abstract:

:Electron-microscopic analysis of the ultrastructure of the Krebs-2 carcinoma ascites cells in the first 90 min immediately after their exposure to fragmented double-stranded DNA has been performed. Morphological attributes of the treated cancer cells indicate the induction in these cells of destructive processes of presumably apoptotic type. The predominance of dystrophic-destructive changes in cells after the addition of DNA is supposed to be a consequence of the disturbance in metabolic processes caused by the experimental action.

journal_name

Ultrastruct Pathol

authors

Kirikovich SS,Taranov OS,Omigov VV,Potter EA,Dolgova EV,Proskurina AS,Efremov YR,Bogachev SS

doi

10.1080/01913123.2019.1575499

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

56-65

issue

1

eissn

0191-3123

issn

1521-0758

journal_volume

43

pub_type

杂志文章
  • Sarcomatoid renal cell carcinoma metastatic to the heart: report of a case.

    abstract::An unusual case of metastatic sarcomatoid renal cell carcinoma is presented. Fifteen months after nephrectomy for a typical clear cell carcinoma, a 63-year-old man presented with bilateral pleural effusions, cardiomegaly, and tamponade. A pericardial biopsy showed an anaplastic spindle cell tumor that was strongly ker...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129109016245

    authors: Bird DJ,Semple JP,Seiler MW

    更新日期:1991-07-01 00:00:00

  • Evolutionary origin of eukaryotic cells.

    abstract::This article reviews literature on the transition from rudimentary prokaryotic life to eukaryotes. An overview of the differences between these organisms and theories of eukaryogenesis are reviewed. Various methods of investigating the transformation from prokaryotes to eukaryotes are elaborated, including the fossil,...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.1080/01913120050118521

    authors: Kostianovsky M

    更新日期:2000-03-01 00:00:00

  • Dose-dependent mercuric chloride tubular injury in rat kidney.

    abstract::Mercuric chloride (HgCl(2)) produces an acute renal failure in experimental animal models. Since the mechanism of tubular injury has not completely been clarified, this morpho-quantitative study was undertaken to better understand the effects of 2 sublethal doses (T1=1 mg/kg and T3.5=3.5 mg/kg) of HgCl(2) in rat proxi...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120309921

    authors: Stacchiotti A,Borsani E,Rodella L,Rezzani R,Bianchi R,Lavazza A

    更新日期:2003-07-01 00:00:00

  • Betulinic acid induces apoptosis and ultrastructural changes in MDA-MB-231 breast cancer cells.

    abstract::The aim of this study is to investigate the effects of betulinic acid (BA) on triple-negative breast cancer MDA-MB-231 cells and observe the ultrastructural changes. The concentration of BA required to induce apoptosis in MDA-MB-231 cells has been previously reported. In this study, a cell counting kit-8 proliferation...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2017.1383548

    authors: Gao Y,Ma Q,Ma YB,Ding L,Xu XL,Wei DF,Wei L,Zhang JW

    更新日期:2018-01-01 00:00:00

  • Acral peeling skin syndrome: report of two cases.

    abstract::Peeling skin syndrome is a rare dermatosis characterized by spontaneous and painless peeling of the skin. The authors report two patients with history of spontaneous, asymptomatic, and noninflammatory peeling skin of the acral surfaces after soaking in water. On light microscopy, blisters were located in the mid layer...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120590909867

    authors: García EG,Carreño RG,Martínez González MA,Reyes JJ

    更新日期:2005-01-01 00:00:00

  • A clone of elusive parents: gonadotroph adenoma-female type.

    abstract::A 69-year-old woman presented with visual disturbance. Perimetry testing revealed a bitemporal hemianopia. Brain MRI demonstrated a 2.2-cm gadolinium-enhancing pituitary mass. Previously she had been treated for hypothyroidism, hypertension, and dyslipidemia. She had hyperprolactinemia. Endoscopic transsphenoidal debu...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2011.642465

    authors: Baborie A,Daousi C,Javadpour M,Das K,White H,Macfarlane I,Kovacs K,Horvath E

    更新日期:2012-04-01 00:00:00

  • Differences in nuclear pore density among human choroidal melanoma cell types.

    abstract::Two cases of mixed cell type choroidal melanoma were examined by means of conventional and freeze-fracture electron microscopy. Data on average nuclear pore density were readily collected from freeze-fracture replicas of spindle A, spindle B, and epithelioid cells. Highly significant (p less than 0.001) differences in...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129009032246

    authors: Sacks-Wilner R,Freddo TF

    更新日期:1990-07-01 00:00:00

  • Bartonellosis as cause of death after red blood cell unit transfusion.

    abstract::The authors present the case of a young man with aplastic anemia who went into shock and died after several red blood cell unit transfusions. Immunohematological studies did not show any abnormality and blood cultures from patients and blood bags were negative. The ultrastructural findings, allied with current scienti...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120902785567

    authors: Magalhães RF,Urso Pitassi LH,Lania BG,Barjas-Castro ML,Neves Ferreira Velho PE

    更新日期:2009-07-01 00:00:00

  • CD44s and CD44v6 in diagnosis and prognosis of human bladder cancer.

    abstract:UNLABELLED:The cell adhesion molecules (CAMs) CD44 standard (CD44s) and its variant 6 (CD44v6) are involved in the progression and invasion of human malignancies. However, discrepancies in the prognostic value of CD44s and CD44v6 expression need to be addressed. AIMS:To investigate the expression of CD44s and CD44v6 i...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2011.651522

    authors: Omran OM,Ata HS

    更新日期:2012-05-01 00:00:00

  • Immunolocalization of cellular fibronectins in the normal liver, cirrhosis, and hepatocellular carcinoma.

    abstract::Cellular (c) fibronectins (Fn) differ biochemically, immunologically, and functionally from plasma fibronectins (pFn). Most existing data on Fn distribution in the normal and diseased liver require revision because those studies were based on reagents that did not distinguish pFn from cFn and predated the development ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129509014601

    authors: Koukoulis GK,Shen J,Virtanen I,Gould VE

    更新日期:1995-01-01 00:00:00

  • Adult neuroblastoma of bone: a case report.

    abstract::Adult neuroblastoma is an uncommon tumor and it is rare for one to present as a primary bone lesion. We report the case of a 23-year-old man in whom the tumor initially appeared in the right scapula. Light microscopic, immunocytochemical, and electron microscopic findings were typical of neuroblastoma. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913128709048440

    authors: Mackay B,Ordóñez NG

    更新日期:1987-01-01 00:00:00

  • As you like it, Part 3: A critique and historical review of calcification as seen with the electron microscope.

    abstract::As You Like It, Part 3, is a continuation of the lectures given by the author (Ultra Path VIII and Ultra Path IX). It is a critical historical review of topics of interest to electron microscopists, attempting to show what went wrong and perhaps also why. The topics chosen this time demonstrate the prominent role elec...

    journal_title:Ultrastructural pathology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1080/019131201300343874

    authors: Ghadially FN

    更新日期:2001-05-01 00:00:00

  • An unusual pattern of peritubular capillary injury involving apoptosis in a renal transplant patient.

    abstract::Microvascular injury is an important factor in renal allograft survival. Repeated episodes of endothelial injury from chronic antibody-mediated rejection typically manifest at the ultrastructural level as circumferential multilayering of remodeled glomerular basement membrane material and peritubular capillary basal l...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2018.1484542

    authors: Brealey JK,Cassidy J,Manavis J

    更新日期:2018-07-01 00:00:00

  • SEM Study of apical morphological alterations in primary teeth with vital and necrotic pulps.

    abstract::This study evaluated, by SEM, the morphology of human primary teeth roots. Twenty-four teeth were divided into 3 groups: pulp vitality (group I) and pulp necrosis without (group II) and with apical periodontitis (group III). Roots were analyzed by the presence of periodontal ligament (PDL) fibers and resorption areas....

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913120903275642

    authors: da Silva LA,Fernandes PM,da Silva RA,Nelson-Filho P,Rocha LB,Rossi MA

    更新日期:2009-10-01 00:00:00

  • Weber-Christian disease associated with the tip variant of focal segmental glomerulosclerosis: a case report.

    abstract::Weber-Christian disease (W-CD) is associated with relapsing nodular panniculitis and a variety of systemic findings. Renal parenchymal involvement has been rarely reported. The authors describe a case of nephrotic syndrome in an African-American man with a W-CD flare. The patient had chills and low-grade fever with pa...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2012.736459

    authors: Sterling KA,Karam S,Taylor N,Cathro HP

    更新日期:2012-12-01 00:00:00

  • Ultrastructural and histochemical study of the motor end plates of the intrinsic laryngeal muscles in amyotrophic lateral sclerosis.

    abstract::Motor end plates of the intrinsic laryngeal muscles in amyotrophic lateral sclerosis (ALS) were examined light and electron microscopically. Light microscopically, typical neurogenic changes such as small angulated fibers and grouped atrophy were found in the intrinsic laryngeal muscles. Acetylcholinesterase (AchE) ac...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129809032266

    authors: Yoshihara T,Ishii T,Iwata M,Nomoto M

    更新日期:1998-03-01 00:00:00

  • Unusual pigmented vesical lesion in a middle-aged woman.

    abstract::Excess lipofuscin deposition in tissues is a phenomenon observed in normal aging. The amount of lipofuscin in myocardium, liver, skeletal muscle, and adnexal skin structures varies considerably with age and increases in older individuals. In addition, lipofuscin deposition occurs in association with specific, non-age-...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129009076140

    authors: Herrera GA,Turbat-Herrera EA,Lockard VG

    更新日期:1990-11-01 00:00:00

  • Chromogranin A and vesicular monoamine transporter 2 immunolocalization in protein bodies of human locus coeruleus neurons.

    abstract::Our previous histochemical and ultrastructural studies have identified, in human catecholamine neurons, abundant spherical acidophilic protein bodies (pb), which originate from regular mitochondria, retaining their double membrane. In locus coeruleus (LC) neurons, pb have somatodendritic distribution and are unequivoc...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2012.750410

    authors: Kloukina-Pantazidou I,Chrysanthou-Piterou M,Havaki S,Issidorides MR

    更新日期:2013-04-01 00:00:00

  • Primary ependymoma of the retropubic space in a male patient.

    abstract::We report a case of primary intraabdominal ependymoma arising in the retropubic space of a male patient. An incidental intraabdominal mass was discovered in a 51-year-old man. Radiological studies revealed a 10 cm, solid and cystic tumor located in the Retzius fossa. Microscopically, the lesion was characterized by mu...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2020.1836104

    authors: Tasar Kapakli E,Kosemehmetoglu K,Kaymaz F,Akdogan B,Ozmen M,Baydar DE

    更新日期:2020-11-20 00:00:00

  • Malignant enterochromaffinlike cell carcinoid of the gastric stump: an ultrastructural study.

    abstract::A metastasizing carcinoid of the gastric stump found 25 years after Billroth II gastric resection for duodenal ulcer is described. Electron microscopy and optical endocrine cell staining proved the tumor to be composed of enterochromaffinlike (ECL) cells. This unusual combination further shows that, at variance with m...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129109021888

    authors: D'Adda T,Azzoni C,Franzé A,Bordi C

    更新日期:1991-05-01 00:00:00

  • Ultrastructure of HIV/AIDS.

    abstract::Transmission electron microscopy has played a key role in our understanding of the human immunodeficiency virus and the opportunistic infections that accompany HIV disease. This paper describes features of HIV production; HHV-8, the virus that is associated with Kaposi sarcoma; Trachipleistophora anthropophthera, a ne...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章,评审

    doi:10.1080/01913120290104502

    authors: Orenstein JM

    更新日期:2002-07-01 00:00:00

  • Histological and biochemical effects of dexmedetomidine on liver during an inflammatory bowel disease.

    abstract::Inflammation in the liver is an extraintestinal manifestation that is frequently seen during inflammatory bowel diseases (IBD). The authors investigated histopathologycal, ultrastructural and antioxidant effects of dexmedetomidine (Dex) on liver during trinitrobenzene sulfonic acid (TNBS)-induced inflammatory bowel di...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2013.829150

    authors: Gul M,Kayhan B,Elbe H,Dogan Z,Otlu A

    更新日期:2015-02-01 00:00:00

  • Value of electron microscopy in the diagnosis of glomerular diseases.

    abstract::To evaluate the contribution of electron microscopy to the final diagnosis of glomerulopathies, the authors established a prospective study during the first semester of 2006. A total of 52 kidney biopsies were performed with 3 samples for light microscopy, immunofluorescence, and electron microscopy. Among these renal...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913120903506637

    authors: Darouich S,Goucha RL,Jaafoura MH,Moussa FB,Zekri S,Maiz HB

    更新日期:2010-04-01 00:00:00

  • Ultrastructural defects of the glomerular basement membranes associated with primary glomerular nephropathies.

    abstract::It is generally accepted that a glomerular basement membrane (GBM) thinner than 200 nm should be considered below normal. When this abnormality has a global and diffuse distribution, the associated clinical condition is a benign familial hematuria related to mutations of the COL4A4/COL4A3 genes, or an Alport syndrome....

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120490445016

    authors: Mandache E,Gherghiceanu M

    更新日期:2004-03-01 00:00:00

  • Ultrastructural phenotype of "intestinal-type" cells in columnar-lined esophagus.

    abstract::An intestinal-type epithelium is often present at columnar-lined esophagus, gastroesophageal junction or within the so-called short segment Barrett's esophagus, but ultrastructural study failed to detect enterocytes in columnar-lined esophagus. The authors have analyzed the intestinal aspects present in areas of colum...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913120252959281

    authors: Sbarbati A,Faccioli N,Ricci F,Merigo F,Benati D,Castaldini G,Cordiano C,Osculati F

    更新日期:2002-03-01 00:00:00

  • Ultrastructural changes in epithelial cells of rats exposed to low concentration of hydrogen sulfide for 50 days.

    abstract::Hydrogen sulfide (H2S) and other volatile sulfur compounds (VSCs) appear mainly in the oral air of patients with halitosis. It seems that VSCs are directly involved in the pathogenesis of gingival diseases. In previous studies, short-term (7 hours-4 days), high concentrations (5-400 ppm) of H2S applications on periodo...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.1080/01913123.2016.1234530

    authors: Yalçın Yeler D,Aydın M,Hocaoğlu PT,Koraltan M,Özdemir H,Kotil T,Gül M

    更新日期:2016-11-01 00:00:00

  • Extrusion of amyloid fibrils to the extracellular space in experimental mesangial AL-amyloidosis: transmission and scanning electron microscopy studies and correlation with renal biopsy observations.

    abstract::In vitro studies have provided much information regarding the process of glomerular AL-amyloidogenesis. Research efforts have been successful in deciphering how glomerulopathic light chains interact with mesangial cells. The sequential steps involved in the genesis of amyloid fibrils include interactions with surface ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2013.861568

    authors: Teng J,Turbat-Herrera EA,Herrera GA

    更新日期:2014-04-01 00:00:00

  • Angiomyolipoma of the kidney with lymph node involvement.

    abstract::A case of renal angiomyolipoma with regional lymph node involvement is added to 20 cases previously reported. This represents the 11th case reported in a non-tuberous sclerosis patient. The electron microscopic features of the tumor are discussed and correlated with the light microscopic findings. ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913129109016260

    authors: Ansari SJ,Stephenson RA,Mackay B

    更新日期:1991-07-01 00:00:00

  • Unexpected Fabry disease in a renal allograft kidney: an underrecognized cause of poor allograft function.

    abstract::Fabry disease is an X-linked recessive lysosomal storage disease caused by a deficiency of α-galactosidase A, with characteristic ultrastructural cytoplasmic myelin-like inclusions. Renal lesions are seen in male and variably in heterozygous female patients. One previous report has described Fabry disease involving a ...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2010.538136

    authors: Kochar O,Wick MR,Kerr SE,Oglesbee D,Cathro HP

    更新日期:2011-04-01 00:00:00

  • Enhancement of intracellular delivery of anti-cancer drugs by the Tat peptide.

    abstract::The arginine-rich cationic Tat peptides have been reported to enhance the intracellular delivery of macromolecules, including DNA, RNA, and proteins. In this work an arginine cationic peptide derived from the HIV-1 Tat protein was conjugated with noncovalent bonds to sulfonated aluminum phthalocyanine (AlPcS, a photos...

    journal_title:Ultrastructural pathology

    pub_type: 杂志文章

    doi:10.3109/01913123.2011.557522

    authors: Zhao JF,Chen JY,Mi L,Wang PN,Peng Q

    更新日期:2011-05-01 00:00:00