Abstract:
:Two cases of mixed cell type choroidal melanoma were examined by means of conventional and freeze-fracture electron microscopy. Data on average nuclear pore density were readily collected from freeze-fracture replicas of spindle A, spindle B, and epithelioid cells. Highly significant (p less than 0.001) differences in pore densities were found among the three cell types. Pore density was lowest in spindle A cells, intermediate in spindle B cells, and highest in epithelioid cells. The possible relationship between nuclear pore density and nucleolar activity as well as the potential usefulness of this new finding as a prognostic indicator in cases of choroidal melanoma are discussed.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Sacks-Wilner R,Freddo TFdoi
10.3109/01913129009032246subject
Has Abstractpub_date
1990-07-01 00:00:00pages
311-9issue
4eissn
0191-3123issn
1521-0758journal_volume
14pub_type
杂志文章abstract::It is generally accepted that a glomerular basement membrane (GBM) thinner than 200 nm should be considered below normal. When this abnormality has a global and diffuse distribution, the associated clinical condition is a benign familial hematuria related to mutations of the COL4A4/COL4A3 genes, or an Alport syndrome....
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120490445016
更新日期:2004-03-01 00:00:00
abstract::A case of renal angiomyolipoma with regional lymph node involvement is added to 20 cases previously reported. This represents the 11th case reported in a non-tuberous sclerosis patient. The electron microscopic features of the tumor are discussed and correlated with the light microscopic findings. ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109016260
更新日期:1991-07-01 00:00:00
abstract::Finger pulp biopsies of 31 patients suffering from Raynaud's syndrome (RS) were investigated by light and electron microscopy. The patients suffered from various underlying diseases. Interest was focused on the vascular changes and nerve and connective tissue alterations, especially the elastic fiber changes. In the d...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128209016642
更新日期:1982-04-01 00:00:00
abstract::A middle-aged Japanese woman visited the Orthopedics Department of Nihon University Nerima Hikarigaoka Hospital complaining of pain in the left hip joint that had started approximately 8 months earlier. Following several examinations, including imaging diagnoses, an incisional biopsy demonstrated a malignant acetabula...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120701515272
更新日期:2007-07-01 00:00:00
abstract::A cystadenoma arose in the urachus of a 32-year-old man. The mass was a multilocular cystic tumor filled with light yellow mucoid material. It was located in the anterior abdominal wall between the umbilicus and the dome of the urinary bladder. Overall, the mass was 14 cm x 8 cm x 5 cm, with the largest internal cyst ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409023225
更新日期:1994-09-01 00:00:00
abstract::The study aims to investigate the protective effect of Pimpinella anisum oil on aspartame (ASP) which resulted in cerebellar changes. The rats were divided into four equal groups: Group 1: (control group): served as control animals. Group 2: control P. anisum oil received .5 mL/kg/d/b wt. once daily. Group 3 (ASP grou...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.889259
更新日期:2014-05-01 00:00:00
abstract::The authors present the case of a young man with aplastic anemia who went into shock and died after several red blood cell unit transfusions. Immunohematological studies did not show any abnormality and blood cultures from patients and blood bags were negative. The ultrastructural findings, allied with current scienti...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913120902785567
更新日期:2009-07-01 00:00:00
abstract::Abstract Metastases to the pituitary occur more frequently in patients with widespread cancer and mainly involve the posterior lobe. A few cases of metastatic carcinoma to a pituitary adenoma have been described so far. Here, the authors present an additional case of a clear cell renal cell carcinoma (CCRCC) metastati...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.3109/01913123.2014.937843
更新日期:2014-12-01 00:00:00
abstract::The objective of this study was to investigate the ultrastructural characteristics of hybrid acute leukemia (HAL). Fifteen cases of HAL were studied by transmission electron microscopy (TEM), focusing on organelles and myeloperoxidase (MPO) reaction of leukemic cells. By TEM, 5 out 15 cases of HAL were consistent with...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/019131290968722
更新日期:2005-09-01 00:00:00
abstract::Eighty-four cortical neoplasms were studied for cytokeratin and vimentin expression by immunohistochemistry and for intermediate filament aggregates by electron microscopy. Twenty oncocytomas expressed cytokeratin, 16 in a distinctive punctate pattern. These same 16 tumors also contained small globular filamentous bod...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129109016259
更新日期:1991-07-01 00:00:00
abstract::This article reviews literature on the transition from rudimentary prokaryotic life to eukaryotes. An overview of the differences between these organisms and theories of eukaryogenesis are reviewed. Various methods of investigating the transformation from prokaryotes to eukaryotes are elaborated, including the fossil,...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/01913120050118521
更新日期:2000-03-01 00:00:00
abstract::Six intradermal melanocytic nevi, two with and four without intercellular slitlike spaces, were examined by light microscopy and electron microscopy of deparaffinized tissue. The spaces were partially lined by elongated nevus cells and contained a few collagen fibrils. Other features in both groups included an abundan...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128009141438
更新日期:1980-07-01 00:00:00
abstract::Sibutramine is used in the treatment of obesity due to its ability to influence feelings of hunger and satiety by inhibiting the re-uptake of serotonin and noradrenalin in the central nervous system (CNS). Sibutramine use has been associated with numerous adverse events in particular cardiovascular complications possi...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.946635
更新日期:2014-12-01 00:00:00
abstract::Hydrogen sulfide (H2S) and other volatile sulfur compounds (VSCs) appear mainly in the oral air of patients with halitosis. It seems that VSCs are directly involved in the pathogenesis of gingival diseases. In previous studies, short-term (7 hours-4 days), high concentrations (5-400 ppm) of H2S applications on periodo...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2016.1234530
更新日期:2016-11-01 00:00:00
abstract::A 28-year-old man presented with left cervical lymph node metastases and a 7-cm mass in the left lobe of the liver. Biopsy material from both sites revealed a fibrolamellar hepatocarcinoma (FLHC) with immunocytochemical and ultrastructural evidence of neurosecretory differentiation. The patient refused treatment. He d...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129409016302
更新日期:1994-01-01 00:00:00
abstract::A technique is described in which areas of large Spurr epoxy thick sections are directly popped off of glass slides by inverted Beem capsules filled with polymerized plastic. This technique allows the survey of large regions of tissue with the maintenance of tissue relationships and the selection of specific areas for...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409018580
更新日期:1984-01-01 00:00:00
abstract::A spectrum of 24 benign and malignant nerve sheath tumors and 10 non-neural spindle-cell tumors were studied by light microscopy for the presence of glial fibrillary acidic protein (GFAP) immunoreactivity by the peroxidase-antiperoxidase (PAP) technique. In 8 cases, these results were compared to their electron micros...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128409141487
更新日期:1984-01-01 00:00:00
abstract::Mitochondrial morphology was studied in 60 renal epithelial neoplasms, including clear cell, papillary, chromophobe cell, and oncocytomas, to see if there are significant differences among the various subtypes. Mitochondria from the nephron tubular system obtained from 36 patients with glomerular diseases served as co...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129709021939
更新日期:1997-09-01 00:00:00
abstract::Thickening of capillary walls is a feature of many glomerular diseases. Widening of the wall may be produced by deposits and other changes affecting either subepithelial and subendothelial regions or the glomerular basement membrane itself. Careful light microscopic examination using special stains can distinguish som...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128309140784
更新日期:1983-03-01 00:00:00
abstract::Aggregates of parallel microtubules have been found within cisternae of the rough endoplasmic reticulum in cells of six human metastatic melanomas. The tubules have a uniform diameter and regular spacing and in longitudinal sections can be seen to possess a fine periodicity. They are compared with tubuloreticular incl...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128009141389
更新日期:1980-01-01 00:00:00
abstract::The ultrastructure of a benign uterine epithelioid leiomyoma with prominent clear cells ("leiomyoblastoma") was studied to define the subcellular changes that yield the distinctive light microscopic pattern of this rare lesion. The main constituent of the cytoplasm was multiple cytolysosomes composed of vesicular, mem...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128609032224
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Low-frequency noise (LFN) is a ubiquitous physical stressor known to cause degenerative cellular changes and organ alterations with functional repercussions both in humans and animals. MATERIALS AND METHODS:After acceptance of the study protocol by a local ethics committee, 20 Wistar rats were randomly di...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.1080/01913123.2017.1336188
更新日期:2017-07-01 00:00:00
abstract::We describe in this work the presence of extracellular vesicles (EVs) along different cell types, especially cordocytes, in various clinical conditions of the human brain (atherothrombotic disease, cerebral tumors, hygroma durae matris, intracerebral cysts, Moyamoya disease and parenchymatous hematoma) using transmiss...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2014.981327
更新日期:2015-05-01 00:00:00
abstract::Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare aggressive lymphoma derived from plasmacytoid dendritic cells or precursor dendritic cells. Despite some 240 reported cases, its morphology and especially ultrastructure has not been satisfactorily studied. A case is reported of a 13 year old boy, who, des...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2013.813998
更新日期:2014-02-01 00:00:00
abstract::Weber-Christian disease (W-CD) is associated with relapsing nodular panniculitis and a variety of systemic findings. Renal parenchymal involvement has been rarely reported. The authors describe a case of nephrotic syndrome in an African-American man with a W-CD flare. The patient had chills and low-grade fever with pa...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2012.736459
更新日期:2012-12-01 00:00:00
abstract::To evaluate the contribution of electron microscopy to the final diagnosis of glomerulopathies, the authors established a prospective study during the first semester of 2006. A total of 52 kidney biopsies were performed with 3 samples for light microscopy, immunofluorescence, and electron microscopy. Among these renal...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913120903506637
更新日期:2010-04-01 00:00:00
abstract::Deciduoid mesothelioma was first described in young females and in the peritoneum, which led to the suggestion that deciduoid mesothelioma was a distinct subtype with specific clinical and pathologic features. Later reports, however, have shown that this type of mesothelioma may also occur in elderly people and in the...
journal_title:Ultrastructural pathology
pub_type: 杂志文章,评审
doi:10.1080/0913120290104647
更新日期:2002-11-01 00:00:00
abstract::A technique for immunoelectron microscopy is described whereby tissue is embedded in large (6 x 12 mm) plastic blocks and reembedded ("popped off") directly from semithin (3-microns) sections for thin sectioning. This technique is particularly useful in locating relatively sparse cells or tissue structures. Three acry...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913129209074550
更新日期:1992-01-01 00:00:00
abstract::Amyloid depositions of pancreatic islets were investigated with electron microscopy in a case of type III glycogenosis. Beta cells adjoining small amyloid depositions were shown to have cytoplasmic invaginations where closely packed amyloid fibrils were disclosed regularly orientated amyloid bundles. In the cytoplasm ...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913128609032222
更新日期:1986-01-01 00:00:00
abstract::Myeloid histocytes of dendritic cells (DCs), Langerhans cells (LCs), and macrophages in varied tissues, as leukemic blasts in acute monoblastic and monocytic leukemia (AML-M5a and M5b), are derived from monocyte progenitors in bone marrow. Based on DC induction from hematopoietic stem cells, myeloid progenitors, and m...
journal_title:Ultrastructural pathology
pub_type: 杂志文章
doi:10.3109/01913123.2015.1120838
更新日期:2016-01-01 00:00:00