Abstract:
:A 69-year-old woman presented with visual disturbance. Perimetry testing revealed a bitemporal hemianopia. Brain MRI demonstrated a 2.2-cm gadolinium-enhancing pituitary mass. Previously she had been treated for hypothyroidism, hypertension, and dyslipidemia. She had hyperprolactinemia. Endoscopic transsphenoidal debulking improved her visual field defects. Histology showed a chromophobic adenoma. Electron microscopy showed elongated, polar cells with long, slender processes. The small uniform secretory granules were peripherally disposed, collecting heavily within cell processes. Based on electron microscopical characteristics the tumor is consistent with an ACTH-negative female gonadotroph adenoma. The parent cell of this rare variant of a pituitary adenoma is yet unknown.
journal_name
Ultrastruct Patholjournal_title
Ultrastructural pathologyauthors
Baborie A,Daousi C,Javadpour M,Das K,White H,Macfarlane I,Kovacs K,Horvath Edoi
10.3109/01913123.2011.642465subject
Has Abstractpub_date
2012-04-01 00:00:00pages
85-8issue
2eissn
0191-3123issn
1521-0758journal_volume
36pub_type
杂志文章abstract::Dysembryoplastic neuroectodermal tumor (DNT) is a rare brain neoplasm. Although the tumor pathology is relatively well charactererized, its full clinicopathological spectrum is still discussed, and ultrastructural data on it are very limited. Here, the authors describe detailed ultrastructural pathology of 7 cases of ...
journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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更新日期:2010-10-01 00:00:00
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journal_title:Ultrastructural pathology
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journal_title:Ultrastructural pathology
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