Xanthogranulomatous appendicitis--an incidental finding of localized pathology.

Abstract:

:The clinical, histopathological, and electron microscopic features of an unusual case of xanthogranulomatous appendicitis are reported. The patient, a 37-year-old female, presented with typical signs of acute appendicitis and the appendix appeared slightly dilated at laparatomy. The histopathological sections showed numerous xanthoma cells mixed with inspissated fecaliths. Electron microscopy disclosed the presence of xanthoma cells filled with electron-lucent lipid droplets of variable size. The ultrastructural characteristics of these cells enabled the distinction of two types of lipid-laden histiocytes, in relationship to the size of the lipid droplets. Since the lipid droplets were seen also in cells other than histiocytes, it appears that these changes are secondary to a common mechanism, comprising factors such as obstruction, hemorrhage, inflammation, and local hypoxia.

journal_name

Ultrastruct Pathol

authors

Munichor M,Kerner H,Cohen H,Bickel A,Iancu TC

doi

10.1080/019131200281291

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

33-9

issue

1

eissn

0191-3123

issn

1521-0758

journal_volume

24

pub_type

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