Citric acid production from extract of Jerusalem artichoke tubers by the genetically engineered yeast Yarrowia lipolytica strain 30 and purification of citric acid.

abstract：:Industrial grade soluble corn starch was used directly and effectively as the fermentation substrate for microbial exopolysaccharides production. Bacillus subtilis mutant strain NJ308 grew with untreated starch raw material as the sole carbon source. The real-time PCR results demonstrated that up-regulated genes encod...

journal_title：Bioprocess and biosystems engineering

authors： He X,He F,Hang J,Li H,Chen Y,Wei P,Chen K,Li Y,OuYang P

更新日期：2018-06-01 00:00:00

abstract：:Novel strategies to facilitate the transition from batch to continuous simultaneous saccharification and fermentation were studied in this work. Implementing these strategies in bioethanol production plants to change production to a continuous mode will avoid large modifications in the process configuration. Therefore...

journal_title：Bioprocess and biosystems engineering

authors： López-Abelairas M,Pena R,Fleischhacker L,Lú-Chau TA,Lema JM

更新日期：2013-12-01 00:00:00

abstract：:The effect of a well-defined mild shear stress on hybridoma cell viability (HB-8852) in a serum-free culture medium has been analysed, and the role as shear protector of different concentrations of fetal bovine serum have been studied. Samples harvested from cultures in their late exponential growth phase, were subjec...

journal_title：Bioprocess and biosystems engineering

authors： Legazpi L,Laca A,Díaz M

更新日期：2009-10-01 00:00:00

abstract：:This work aimed to develop an optimal carbon source feeding strategy to achieve maximal production of heparosan as a precursor of bioengineered heparin by Escherichia coli K5. Glycerol gave higher heparosan titer and productivity compared to glucose. The maximum heparosan production (187 mg/L) and heparosan productivi...

journal_title：Bioprocess and biosystems engineering

authors： Liu Y,Liu L,Chen J,Li J,Du G,Chen J

更新日期：2012-09-01 00:00:00

abstract：:Sorghum stalks were evaluated to generate clean sugars; enzymatic hydrolysis efficiency of acid pretreated biomass was significantly low (12.3 g sugar/g pretreated biomass) compared to alkali method (49.1 g sugar/g pretreated biomass). Inhibitory compounds derived from acid pretreatment, such as hydroxymethyl furfural...

journal_title：Bioprocess and biosystems engineering

authors： Lee JE,Guragain YN,Bastola KP,Vadlani PV

更新日期：2017-04-01 00:00:00

abstract：:Colony development of the dimorphic yeasts Yarrowia lipolytica and Candida boidinii on solid agar substrates under glucose limitation served as a model system for mycelial development of higher filamentous fungi. Strong differences were observed in the behaviour of both yeasts: C. boidinii colonies reached a final col...

journal_title：Bioprocess and biosystems engineering

authors： Walther T,Reinsch H,Weber P,Ostermann K,Deutsch A,Bley T

更新日期：2011-01-01 00:00:00

abstract：:Calcitriol is an important drug used for treating osteoporosis, which can be produced from vitamin D3. The current method of producing calcitriol from vitamin D3 during cultivation of microbial cells results in low yields of calcitriol and high purification costs. Therefore, in this study, the steps of cell cultivatio...

journal_title：Bioprocess and biosystems engineering

authors： Kang DJ,Im JH,Kang JH,Kim KH

更新日期：2015-07-01 00:00:00

abstract：:This study proposes a microfluidic device capable of separating monocytes from a type of cancer cell that is called T-cell acute lymphoblastic leukemia (RPMI-8402) in a continuous flow using negative and positive dielectrophoretic forces. The use of both the hydrodynamic and dielectrophoretic forces allows the separat...

journal_title：Bioprocess and biosystems engineering

authors： Zahedi Siani O,Zabetian Targhi M,Sojoodi M,Movahedin M

更新日期：2020-09-01 00:00:00

abstract：:A rapid method for designing integrated bioprocesses, using a combination of a windows of operation and a Pareto optimisation approach, is described in this paper. Within bioprocesses, multiple objectives are common, and achieving a satisfactory trade-off amongst the design objectives is crucial. Conventional optimisa...

journal_title：Bioprocess and biosystems engineering

authors： Zhou YH,Titchener-Hooker NJ

更新日期：2003-07-01 00:00:00

abstract：:A novel suspended carrier with porous surface was firstly prepared by coating a sponge on the inside and outside of a hard polyethylene ring. Herein the effects of the sponge thickness (0, 2, 4, 6 mm) and pore size (17, 45, 85 pores per inch, ppi) on the performance of the start-up stage in moving bed biofilm reactor ...

journal_title：Bioprocess and biosystems engineering

authors： Chen X,Kong L,Wang X,Tian S,Xiong Y

更新日期：2015-02-01 00:00:00

abstract：:This study assessed the simultaneous nitrification and denitrification processes and remaining organic matter removal from anaerobic reactor effluent treating wastewater in a single reactor. A structured-bed reactor, with polyurethane foam as support media, was subjected to intermittent aeration and effluent recircula...

journal_title：Bioprocess and biosystems engineering

authors： Silva BG,Damianovic MHRZ,Foresti E

更新日期：2018-08-01 00:00:00

abstract：:The kinetics of the enzymatic transesterification between a mixture of triglycerides (oils) and methanol for biodiesel production in a bis(2-ethylhexyl) sodium sulfosuccinate (AOT)/isooctane reversed micellar system, using recombinant cutinase from Fusarium solani pisi as a catalyst, was investigated. In order to desc...

journal_title：Bioprocess and biosystems engineering

authors： Badenes SM,Lemos F,Cabral JM

更新日期：2011-11-01 00:00:00

abstract：:Lipase (LP) was immobilized on electrospun and ethanol-dispersed polystyrene-poly(styrene-co-maleic anhydride) (PS-PSMA) nanofibers (EtOH-NF) in the form of enzyme precipitate coatings (EPCs). LP precipitate coatings (EPCs-LP) were prepared in a three-step process, consisting of covalent attachment, LP precipitation, ...

journal_title：Bioprocess and biosystems engineering

authors： An HJ,Lee HJ,Jun SH,Hwang SY,Kim BC,Kim K,Lee KM,Oh MK,Kim J

更新日期：2011-09-01 00:00:00

abstract：:Soluble microbial products (SMPs) are considered as the main organic components in wastewater treatment plant effluent from biological wastewater treatment systems. To investigate and explore SMP metabolism pathway for further treatment and control, two innovative mechanistically based activated sludge models were dev...

journal_title：Bioprocess and biosystems engineering

authors： Fan J,Ding Y,Qiu Z,Li W,Lu S

更新日期：2011-11-01 00:00:00

abstract：:An new cascade control system is presented that reproducibly keeps the cultivation part of recombinant protein production processes on its predetermined track. While the system directly controls carbon dioxide production mass and carbon dioxide production rates along their setpoint profiles in fed-batch cultivation, i...

journal_title：Bioprocess and biosystems engineering

authors： Kuprijanov A,Schaepe S,Aehle M,Simutis R,Lübbert A

更新日期：2012-03-01 00:00:00

abstract：:A kinetic model for glucose and xylose co-substrate uptake in Saccharomyces cerevisiae is presented. The model couples the enzyme kinetics with the glucose-dependent genetic expression of the individual transport proteins. This novel approach implies several options for optimizing the co-substrate utilization. Interes...

journal_title：Bioprocess and biosystems engineering

authors： Bertilsson M,Andersson J,Lidén G

更新日期：2008-06-01 00:00:00

abstract：:During the production of bio-based bulk chemicals, such as lactic acid (LA), organic impurities have to be removed to produce a ready-to-market product. A capillary electrophoresis method for the simultaneous detection of LA and organic impurities in less than 10 min was developed. LA and organic impurities were detec...

journal_title：Bioprocess and biosystems engineering

authors： Laube H,Boden J,Schneider R

更新日期：2017-07-01 00:00:00

abstract：:L-aspartate ammonia-lyase from Bacillus sp. YM55-1 (AspB, EC 4.3.1.1) catalyzes the reversible conversion of L-aspartate (Asp) into fumarate and ammonia with a high specific activity toward the substrate. AspB was expressed in Escherichia coli and partially purified by heat precipitation and saturation with ammonium s...

journal_title：Bioprocess and biosystems engineering

authors： Cárdenas-Fernández M,López C,Alvaro G,López-Santín J

更新日期：2012-10-01 00:00:00

abstract：:Discontinuous airlift mixing was realized by injecting pressured air at time intervals with a frequency between 0.033 and 0.25 Hz (at 80 kPa; i.e., every 4-30 s; valve opening time 800 ms) into outdoor flat panel photobioreactors ([Formula: see text]). This caused a flow velocity between 2 and 20 cm s(-1) of the cultu...

journal_title：Bioprocess and biosystems engineering

authors： Leupold M,Hindersin S,Kerner M,Hanelt D

更新日期：2013-11-01 00:00:00

abstract：:The aim of this study is to achieve high-level extracellular production of D-Psicose-3-epimerase (DPE) with recombinant Escherichia coli. High-level production of DPE is one of the key factors in D-Psicose production. In the present study, the gene AAL45544.1 from Agrobacterium tumefaciens str. C58 was modified by art...

journal_title：Bioprocess and biosystems engineering

authors： Gu L,Zhang J,Liu B,Wu C,Du G,Chen J

更新日期：2013-11-01 00:00:00

abstract：:The novel magnetic nanobeads with epoxy groups on the surface were prepared from glycidyl methacrylate (GMA), ethylene glycol dimethacrylate (EGDMA) and hydroxyethyl methacrylate (HEMA) via emulsifier-free emulsion polymerisation, and they were characterized by scanning electron microscopy and vibrating sample magneto...

journal_title：Bioprocess and biosystems engineering

authors： Liu H,Liu J,Tan B,Zhou F,Qin Y,Yang R

更新日期：2012-10-01 00:00:00

abstract：:Fibrous poly(styrene-b-glycidylmethacrylate) brushes were grafted on poly(styrene-divinylbenzene) (P(S-DVB)) beads using surface-initiated atom transfer radical polymerization. Tetraethyldiethylenetriamine (TEDETA) ligand was incorporated on P(GMA) block. The ligand attached beads were used for reversible immobilizati...

journal_title：Bioprocess and biosystems engineering

authors： Bayramoglu G,Karagoz B,Altintas B,Arica MY,Bicak N

更新日期：2011-08-01 00:00:00

abstract：:Antrodia cinnamomea has recently become a well-known medicinal mushroom in Taiwan. Bioactive compounds found in A. cinnamomea include: polysaccharide, sesquiterpene lactone, steroids and triterpenoids. The aim of this study was to evaluate the feasibility of adding citrus peel extract to enhance the formation of bioac...

journal_title：Bioprocess and biosystems engineering

authors： Yang FC,Ma TW,Chuang YT

更新日期：2012-10-01 00:00:00

abstract：:The bacteriostatic properties of carbon disulphide (CS₂) hamper its biodegradation in conventional biofilters. The response of four biofilters operating in downflow mode and reverse-flow mode was compared in a laboratory-scale plant treating CS₂ under sudden short-term changes in operating conditions. A process shutdo...

journal_title：Bioprocess and biosystems engineering

authors： Rojo N,Gallastegui G,Gurtubay L,Barona A,Elías A

更新日期：2013-04-01 00:00:00

abstract：:The design and development of the neural network (NN)-based controller performance for the activated sludge process in sequencing batch reactor (SBR) is presented in this paper. Here we give a comparative study of various neural network (NN)-based controllers such as the direct inverse control, internal model control ...

journal_title：Bioprocess and biosystems engineering

authors： Azwar,Hussain MA,Ramachandran KB

更新日期：2006-03-01 00:00:00

abstract：:The performance and stability of a two-phase partitioning bioscrubber (TPPB) containing 33% (vol.) n-hexadecane as an immiscible phase was investigated during 30 days of continuous gaseous benzene treatment. Elimination capacities of 141 +/- 12 g/m(3) h were achieved by Achromobacter xylosoxidans Y234 while maintainin...

journal_title：Bioprocess and biosystems engineering

authors： Nielsen DR,Sask KN,McLellan PJ,Daugulis AJ

更新日期：2006-10-01 00:00:00

abstract：:A strain designated M866, producing kojic acid with a high yield, was obtained by combining induced mutation using ion beam implantation and ethyl methane sulfonate treatment of a wild type strain of Aspergillus oryzae B008. The amount of kojic acid produced by the strain M866 in a shaking flask was 40.2 g/L from 100 ...

journal_title：Bioprocess and biosystems engineering

authors： Yan S,Tang H,Wang S,Xu L,Liu H,Guo Y,Yao J

更新日期：2014-06-01 00:00:00

abstract：:The effluent from the biogas process was tested as a nutrient source during cultivation of the protein-rich and edible microalgae Spirulina (Arthrospira platensis) and compared with conventional Spirulina medium. Equal biomass production was observed until late exponential phase and no significant differences could be...

journal_title：Bioprocess and biosystems engineering

authors： Hultberg M,Lind O,Birgersson G,Asp H

更新日期：2017-04-01 00:00:00

abstract：:Bacillus sp. BC-001 was first reported as a potent thermotolerant and homofermentative strain for an industrial-scale L-lactate production. In a flask culture, this isolate fermented both glucose and sucrose to lactate with high yield (0.96 and 0.87 g/g) and productivity (2.8 and 2.6 g/L h), respectively. The higher l...

journal_title：Bioprocess and biosystems engineering

authors： Thitiprasert S,Kodama K,Tanasupawat S,Prasitchoke P,Rampai T,Prasirtsak B,Tolieng V,Piluk J,Assabumrungrat S,Thongchul N

更新日期：2017-12-01 00:00:00

abstract：:Fibrinolytic proteases are enzymes that degrade fibrin. They provide a promising alternative to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus Mucor subtilissimus UCP 1262 was purified in three steps by ammonium sulfate fractionation, ion exchange, and molecular exclusion chro...

journal_title：Bioprocess and biosystems engineering

authors： Nascimento TP,Sales AE,Porto TS,Costa RMPB,Breydo L,Uversky VN,Porto ALF,Converti A

更新日期：2017-08-01 00:00:00