Effects of carbon sources and feeding strategies on heparosan production by Escherichia coli K5.

abstract：:This study aimed to assess the variability in respect of titer and properties of xylanase from Trichoderma reesei SAF3 under both solid-state and submerged fermentation. SSF was initially optimized with different agro-residues and among them wheat bran was found to be the best substrate that favored maximum xylanase p...

journal_title：Bioprocess and biosystems engineering

authors： Kar S,Sona Gauri S,Das A,Jana A,Maity C,Mandal A,Das Mohapatra PK,Pati BR,Mondal KC

更新日期：2013-01-01 00:00:00

abstract：:Two laboratory-scale expanded granular sludge bed (EGSB) reactors were operated at 18 and 25 °C, respectively, for the treatment of synthetic wastewater composed of ethanol and 1-methoxy-2-propanol (M2P) in a mass ratio of 4:1. Reactors were operated first with continuous wastewater supply and after with discontinuous...

journal_title：Bioprocess and biosystems engineering

authors： Lafita C,Penya-roja JM,Gabaldón C

更新日期：2015-11-01 00:00:00

abstract：:The proteolysis of cheese whey with the aid of immobilized enzymes is an attractive alternative for this by-product of the dairy industry. Among some possible applications for whey protein hydrolysates, one may cite their use as protein source for individuals with reduced capacity of digestion, or with genetic metabol...

journal_title：Bioprocess and biosystems engineering

authors： Pinto GA,Giordano RL,Giordano RC

更新日期：2009-01-01 00:00:00

abstract：:In this study, a new-generation subsurface upflow wetland (SUW) system packed with the unique sorption media was introduced for nutrient removal. To explore the interface between hydraulic and environmental performance, a tracer study was carried out in concert with a transport model to collectively provide hydraulic ...

journal_title：Bioprocess and biosystems engineering

authors： Chang NB,Xuan Z,Wanielista MP

更新日期：2012-03-01 00:00:00

abstract：:A highly efficient β-1,4-mannanase-secreting strain, Pholiota adiposa SKU0714, was isolated and identified on the basis of its morphological features and sequence analysis of internal transcribed spacer rDNA. P. adiposa β-1,4-mannanase was purified to homogeneity from P. adiposa culture supernatants by one-step chroma...

journal_title：Bioprocess and biosystems engineering

authors： Ramachandran P,Zhao Z,Singh R,Dhiman SS,Choi JH,Kim D,Haw JR,Lee JK

更新日期：2014-09-01 00:00:00

abstract：:tert-Butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate [(3R,5S)-CDHH] is the key chiral intermediate to synthesize the side chain of the lipid-lowering drug rosuvastatin. Carbonyl reductases showed excellent activity for the biosynthesis of (3R,5S)-CDHH. The requirement of cofactor NADH/NADPH leads to high cost for the in...

journal_title：Bioprocess and biosystems engineering

authors： Zhang XJ,Wang WZ,Zhou R,Liu ZQ,Zheng YG

更新日期：2020-01-01 00:00:00

abstract：:A kinetic model for glucose and xylose co-substrate uptake in Saccharomyces cerevisiae is presented. The model couples the enzyme kinetics with the glucose-dependent genetic expression of the individual transport proteins. This novel approach implies several options for optimizing the co-substrate utilization. Interes...

journal_title：Bioprocess and biosystems engineering

authors： Bertilsson M,Andersson J,Lidén G

更新日期：2008-06-01 00:00:00

abstract：:An optimized repeated-fed-batch fermentation process for the synthesis of dihydroxyacetone (DHA) from glycerol utilizing Gluconobacter oxydans is presented. Cleaning, sterilization, and inoculation procedures could be reduced significantly compared to the conventional fed-batch process. A stringent requirement was tha...

journal_title：Bioprocess and biosystems engineering

authors： Hekmat D,Bauer R,Fricke J

更新日期：2003-12-01 00:00:00

abstract：:A rapid method for designing integrated bioprocesses, using a combination of a windows of operation and a Pareto optimisation approach, is described in this paper. Within bioprocesses, multiple objectives are common, and achieving a satisfactory trade-off amongst the design objectives is crucial. Conventional optimisa...

journal_title：Bioprocess and biosystems engineering

authors： Zhou YH,Titchener-Hooker NJ

更新日期：2003-07-01 00:00:00

abstract：:A concept for the determination of concentrations in microchannels using FT-IR spectroscopy in transmission is presented. The fundamental idea of spatially resolved measurements along several measuring points was implemented in a single-channel microreactor. Compared to existing microreactor setups for the analysis of...

journal_title：Bioprocess and biosystems engineering

authors： Fagaschewski J,Sellin D,Wiedenhöfer C,Bohne S,Trieu HK,Hilterhaus L

更新日期：2015-07-01 00:00:00

abstract：:The influence of sugars in culture media on the kinetics of the mono- and disaccharide uptake and cell growth behavior was studied by mid-infrared spectroscopy using a Fourier transform infrared spectrometer (FT-IR) equipped with an attenuate total reflection accessory (ATR). We performed the plant cell cultivation wi...

journal_title：Bioprocess and biosystems engineering

authors： Yamanaka A,Hashimoto A,Matsuo T,Kanou M,Suehara K,Kameoka T

更新日期：2007-11-01 00:00:00

abstract：:The major nutrients, pH and temperature were evaluated for the exopolysaccharide (EPS) production by Daedalea dickinsii in submerged culture to derive an optimal medium composition and conditions as follows: 50 g/L maltose, 5 g/L soy peptone, 5 mM CaCl(2), at pH 6.0 and 28 °C. A purified EPS fraction was attained from...

journal_title：Bioprocess and biosystems engineering

authors： Mao DB,Shi CW,Wu JY,Xu CP

更新日期：2014-07-01 00:00:00

abstract：:Sodium dodecyl sulfate (SDS) is a widely used anionic surfactant, which finds its way to the receiving water body due to the incapability of conventional wastewater treatment systems to completely remove it. A hybrid treatment system consisting of upflow microbial fuel cell (MFC) with titanium dioxide (TiO2) as a phot...

journal_title：Bioprocess and biosystems engineering

authors： Sathe SM,Bhowmick GD,Dubey BK,Ghangrekar MM

更新日期：2020-11-01 00:00:00

abstract：:The effect of a well-defined mild shear stress on hybridoma cell viability (HB-8852) in a serum-free culture medium has been analysed, and the role as shear protector of different concentrations of fetal bovine serum have been studied. Samples harvested from cultures in their late exponential growth phase, were subjec...

journal_title：Bioprocess and biosystems engineering

authors： Legazpi L,Laca A,Díaz M

更新日期：2009-10-01 00:00:00

abstract：:To obtain the soluble production of recombinant NovQ, it has been constructed into the pET28a system. Unfortunately, NovQ was mostly accumulated as inclusion bodies and existed in insoluble fractions of E. coli cell lysate. Four partners, namely His6, TrxA, GST and MBP, were investigated in fusion expression and co-ex...

journal_title：Bioprocess and biosystems engineering

authors： Ni W,Liu H,Wang P,Wang L,Sun X,Wang H,Zhao G,Zheng Z

更新日期：2019-03-01 00:00:00

abstract：:In this paper, we build bounded error observers for a common class of partially known bioreactor models. The main idea is to construct hybrid bounded observers "between" high gain observer, which has an adjustable convergence rate but requires perfect knowledge of the model, and asymptotic observer which is very robus...

journal_title：Bioprocess and biosystems engineering

authors： Lemesle V,Gouzé JL

更新日期：2005-08-01 00:00:00

abstract：:The discovery of quorum sensing as a mechanism for regulating specific phenotypes in bacteria based on population density has conveyed attention to find molecules capable of interfering quorum sensing networks (QSN) in a process coined quorum quenching. Here, we examined the dynamics of Escherichia coli AI-2 and Pseud...

journal_title：Bioprocess and biosystems engineering

authors： Barrios AF,Covo V,Medina LM,Vives-Florez M,Achenie L

更新日期：2009-06-01 00:00:00

abstract：:Escherichia coli AFP111, a pflB, ldhA, ptsG triple mutant of E. coli W1485, can be recovered for additional succinate production in fresh medium after two-stage fermentation (an aerobic growth stage followed by an anaerobic production stage). However, the specific productivity is lower than that of two-stage fermentat...

journal_title：Bioprocess and biosystems engineering

authors： Ma JF,Jiang M,Chen KQ,Xu B,Liu SW,Wei P,Ying HJ,Chang HN,Ouyang PK

更新日期：2011-05-01 00:00:00

abstract：:A novel and highly stable biomimetic oxidase sensor system was designed for catehol detection. FePP used as biomimetic horseradish peroxidase (HRP) was immobilized onto modified multi-walled carbon nanotubes (MWCNTs). Functional groups such as -OH, -NH2 and -COOH were introduced onto the surface of MWCNTs to provide b...

journal_title：Bioprocess and biosystems engineering

authors： Bin Z,Yanhong C,Jiaojiao X

更新日期：2019-02-01 00:00:00

abstract：:Pullulanase was extracellularly produced with an engineered Escherichia coli with a combined strategy. When auto-induction instead of isopropyl β-D-1-thiogalactopyranoside (IPTG) induction method was implemented, we observed increased extracellular activity (4.2 U ml(-1)) and cell biomass (7.95 g DCW l(-1)). Subsequen...

journal_title：Bioprocess and biosystems engineering

authors： Chen WB,Nie Y,Xu Y,Xiao R

更新日期：2014-04-01 00:00:00

abstract：:We describe a new device with parallel optical measurement of dissolved oxygen (DO) and pH in up to nine shake flasks applicable in any conventional shaking incubator. Measurement ranges are 0-500% of air saturation for oxygen and 5.5-8.5 for pH. It was used to characterize growth profiles of different L-lysine produc...

journal_title：Bioprocess and biosystems engineering

authors： Schneider K,Schütz V,John GT,Heinzle E

更新日期：2010-06-01 00:00:00

abstract：:Changes in the microbial community of an enhanced biological phosphorus removal (EBPR) activated sludge system under different influent phosphorus/carbon (P/C) ratio conditions were investigated through evaluation of population respiratory quinone profiles. A total of 13 types of respiratory quinone homologs consistin...

journal_title：Bioprocess and biosystems engineering

authors： Ahn J,Lee M,Kwon H

更新日期：2006-08-01 00:00:00

abstract：:The effectiveness of coil UV reactor series for the online sterilization of cheese whey was compared to those of the single conventional and coil reactors at various flow rates (5-70 mL/min). The residence time varied from 168 to 12 min and from 48 to 24 min for the single and the series reactors, respectively. Hundre...

journal_title：Bioprocess and biosystems engineering

authors： Singh JP,Ghaly AE

更新日期：2006-10-01 00:00:00

abstract：:Harvesting technology has a significant influence on the microalgal biomass industry. This study develops a buoy-bead flotation method and analyzes the factors impacting flotation. Experimental results show that adding sodium borosilicate as an alternative microsphere material can result in 58.5% harvesting efficiency...

journal_title：Bioprocess and biosystems engineering

authors： Wen H,Zou X,Xu K,Shen Z,Ren X,Li Y

更新日期：2019-03-01 00:00:00

abstract：:Docosahexaenoic acid (DHA) percentage in total fatty acids (TFAs) is an important index in DHA microbial production. In this study, the change of DHA percentage in response to fermentation stages and the strategies to increase DHA percentage were investigated. Two kinds of conventional nitrogen sources, monosodium glu...

journal_title：Bioprocess and biosystems engineering

authors： Ren LJ,Sun LN,Zhuang XY,Qu L,Ji XJ,Huang H

更新日期：2014-05-01 00:00:00

abstract：:The performance of enriched sludge augmented with the B21 strain of Alcaligenes defragrans was compared with that of enriched sludge, as well as with pure Alcaligenes defragrans B21, in the context of a sulfur-oxidizing denitrification (SOD) process. In synthetic wastewater treatment containing 100-1,000 mg NO3-N/L, t...

journal_title：Bioprocess and biosystems engineering

authors： Flores A 3rd,Nisola GM,Cho E,Gwon EM,Kim H,Lee C,Park S,Chung WJ

更新日期：2007-05-01 00:00:00

abstract：:We generated a genetically engineered Klebsiella pneumoniae strain (AK-VOT) to eliminate by-product formation during production of 1,3-propanediol (1,3-PD) from glycerol. In the present study, the glycerol-metabolizing properties of the recombinant strain were examined during fermentation in a 5 L bioreactor. As expec...

journal_title：Bioprocess and biosystems engineering

authors： Oh BR,Seo JW,Heo SY,Hong WK,Luo LH,Son JH,Park DH,Kim CH

更新日期：2012-01-01 00:00:00

abstract：:During ribonucleic acid fermentation, the fermentative processes were researched at pH controlled at 4.0 and under natural conditions. Unstructured models in a 50-L airlift fermentor were established for batch RNA production at pH 4.0 using the Verhulst equation for microbial growth, the Luedeking-Piret equation for p...

journal_title：Bioprocess and biosystems engineering

authors： Li B,Chen X,Ren H,Li L,Xiong J,Bai J,Chen Y,Wu J,Ying H

更新日期：2012-03-01 00:00:00

abstract：:Menaquinone-7 (MK-7), a subtype of vitamin K, has received a significant attention due to its effect on improving bone and cardiovascular health. Current fermentation strategies, which involve static fermentation without aeration or agitation, are associated with low productivity and scale-up issues and hardly justify...

journal_title：Bioprocess and biosystems engineering

authors： Mahdinia E,Demirci A,Berenjian A

更新日期：2017-10-01 00:00:00

abstract：:Rice straw is a lignocellulosic biomass that constitutes a renewable organic substance and alternative source of energy; however, its structure confounds the liberation of monosaccharides. Pretreating rice straw using a TiO(2)/UV system facilitated its hydrolysis with Accellerase 1000(™), suggesting that hydroxyl radi...

journal_title：Bioprocess and biosystems engineering

authors： Kang HK,Kim D

更新日期：2012-01-01 00:00:00