Remote engineering for a cheese whey biorefinery: an Internet-based application for process design, economic analysis, monitoring, and control of multiple plant sites.

Abstract:

:The proteolysis of cheese whey with the aid of immobilized enzymes is an attractive alternative for this by-product of the dairy industry. Among some possible applications for whey protein hydrolysates, one may cite their use as protein source for individuals with reduced capacity of digestion, or with genetic metabolic disorders (phenylketonuria patients, for instance). The multipurpose plant that processes whey is named here as a cheese whey biorefinery. This work presents the remote control and monitoring of the whey biorefineries using the Internet. In an integrated environment, the web application also enables simulation and economic analyses of the process. This technology might allow small companies to access a remote "engineering centre", with know-how on plant design and advanced control techniques. The idea can also be extended to large dairy companies, providing the remote control of geographically spread sites of production.

journal_name

Bioprocess Biosyst Eng

authors

Pinto GA,Giordano RL,Giordano RC

doi

10.1007/s00449-008-0222-8

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

69-78

issue

1

eissn

1615-7591

issn

1615-7605

journal_volume

32

pub_type

杂志文章
  • The effect of discontinuous airlift mixing in outdoor flat panel photobioreactors on growth of Scenedesmus obliquus.

    abstract::Discontinuous airlift mixing was realized by injecting pressured air at time intervals with a frequency between 0.033 and 0.25 Hz (at 80 kPa; i.e., every 4-30 s; valve opening time 800 ms) into outdoor flat panel photobioreactors ([Formula: see text]). This caused a flow velocity between 2 and 20 cm s(-1) of the cultu...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-013-0939-x

    authors: Leupold M,Hindersin S,Kerner M,Hanelt D

    更新日期:2013-11-01 00:00:00

  • Medium modification to enhance the formation of bioactive metabolites in shake flask cultures of Antrodia cinnamomea by adding citrus peel extract.

    abstract::Antrodia cinnamomea has recently become a well-known medicinal mushroom in Taiwan. Bioactive compounds found in A. cinnamomea include: polysaccharide, sesquiterpene lactone, steroids and triterpenoids. The aim of this study was to evaluate the feasibility of adding citrus peel extract to enhance the formation of bioac...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-012-0712-6

    authors: Yang FC,Ma TW,Chuang YT

    更新日期:2012-10-01 00:00:00

  • Pentynyl dextran as a support matrix for immobilization of serine protease subtilisin Carlsberg and its use for transesterification of N-acetyl-L-phenylalanine ethyl ester in organic media.

    abstract::In this study, serine protease (subtilisin Carlsberg) was immobilized on pentynyl dextran (PyD, O-alkynyl ether of dextran, 1) and used for the transesterification of N-acetyl-L-phenylalanine ethyl ester (2) with different aliphatic (1-propanol, 1-butanol, 1-pentanol, 1-hexanol) and aromatic (benzyl alcohol, 2-phenyl ...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-013-1038-8

    authors: Tahir MN,Cho E,Mischnick P,Lee JY,Yu JH,Jung S

    更新日期:2014-04-01 00:00:00

  • Quantitative metabolic flux analysis revealed uneconomical utilization of ATP and NADPH in Acremonium chrysogenum fed with soybean oil.

    abstract::A metabolic network was constructed for the Acremonium chrysogenum cultivation fed with soybean oil. Metabolic flux analysis indicated that the shift from exponential growth to rapid cephalosporin C (CPC) formation was accompanied by 1.63- and 5-fold carbon flux enlargement in TCA cycle and glyoxylate by-pass, respect...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-010-0439-1

    authors: Li J,Yang Y,Chu J,Huang M,Li L,Zhang X,Wang Y,Zhuang Y,Zhang S

    更新日期:2010-11-01 00:00:00

  • Enhancement of nutrient removal performance of activated sludge with a novel hybrid biofilm process.

    abstract::The aim of this study was to investigate the efficacy of a hybrid biofilm pilot-scale treatment plant, designed with a novel configuration by the integration of a fixed-film system, to improve nitrogen removal. The pilot-scale system was established at a wastewater treatment plant in Istanbul and operated based on str...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-018-2042-9

    authors: Güneş G,Hallaç E,Özgan M,Ertürk A,Okutman Taş D,Çokgor E,Güven D,Takacs I,Erdinçler A,Insel G

    更新日期:2019-03-01 00:00:00

  • Product formation kinetics in genetically modified E. coli bacteria: inclusion body formation.

    abstract::A data-driven model is presented that can serve two important purposes. First, the specific growth rate and the specific product formation rate are determined as a function of time and thus the dependency of the specific product formation rate from the specific biomass growth rate. The results appear in form of traine...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-007-0161-9

    authors: Gnoth S,Jenzsch M,Simutis R,Lübbert A

    更新日期:2008-01-01 00:00:00

  • Process optimization of xylanase production using cheap solid substrate by Trichoderma reesei SAF3 and study on the alteration of behavioral properties of enzyme obtained from SSF and SmF.

    abstract::This study aimed to assess the variability in respect of titer and properties of xylanase from Trichoderma reesei SAF3 under both solid-state and submerged fermentation. SSF was initially optimized with different agro-residues and among them wheat bran was found to be the best substrate that favored maximum xylanase p...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-012-0761-x

    authors: Kar S,Sona Gauri S,Das A,Jana A,Maity C,Mandal A,Das Mohapatra PK,Pati BR,Mondal KC

    更新日期:2013-01-01 00:00:00

  • Trametes versicolor laccase production using agricultural wastes: a comparative study in Erlenmeyer flasks, bioreactor and tray.

    abstract::Laccases are very interesting biocatalysts of recognized importance for several industrial applications. Its production by Trametes versicolor, a white-rot fungus, was induced by a combination of cotton gin wastes (1%), a lignocellulosic waste, and vinasse (15%), an industrial by-product from sugarcane industry. The u...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-019-02245-z

    authors: Pinheiro VE,Michelin M,Vici AC,de Almeida PZ,Teixeira de Moraes Polizeli ML

    更新日期:2020-03-01 00:00:00

  • Simultaneous organics removal and bio-electrochemical denitrification in microbial fuel cells.

    abstract::Simultaneous organics removal and bio-electrochemical denitrification using a microbial fuel cell (MFC) reactor were investigated in this study. The electrons produced as a result of the microbial oxidation of glucose in the anodic chamber were transferred to the anode, which then flowed to the cathode in the cathodic...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-007-0164-6

    authors: Jia YH,Tran HT,Kim DH,Oh SJ,Park DH,Zhang RH,Ahn DH

    更新日期:2008-06-01 00:00:00

  • Performance of on-site pilot static granular bed reactor (SGBR) for treating dairy processing wastewater and chemical oxygen demand balance modeling under different operational conditions.

    abstract::The performance and operational stability of a pilot-scale static granular bed reactor (SGBR) for the treatment of dairy processing wastewater were investigated under a wide range of organic and hydraulic loading rates and temperature conditions. The SGBR achieved average chemical oxygen demand (COD), biological oxyge...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-014-1275-5

    authors: Oh JH,Park J,Ellis TG

    更新日期:2015-02-01 00:00:00

  • Production and partial characterization of biosurfactant produced by Streptomyces sp. R1.

    abstract::The present study focused on developing a wild-type actinomycete isolate as a model for a non-pathogenic filamentous producer of biosurfactants. A total of 33 actinomycetes isolates were screened and their extracellular biosurfactants production was evaluated using olive oil as the main substrate. Out of 33 isolates, ...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-017-1764-4

    authors: Zambry NS,Ayoib A,Md Noh NA,Yahya ARM

    更新日期:2017-07-01 00:00:00

  • Influence of photobioreactor configuration on microalgal biomass production.

    abstract::Biodiesel production from microalgae depends on the biomass concentration and lipid content in microalgal cells. Photobioreactors (PBRs) facilitates cultivation of microalgae and renders better process control than open systems. However, reactor configuration and consequential hydrodynamics considerably influence biom...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-020-02342-4

    authors: Banerjee S,Dasgupta S,Das D,Atta A

    更新日期:2020-08-01 00:00:00

  • Recombinase polymerase amplification combined with lateral flow dipstick for equipment-free detection of Salmonella in shellfish.

    abstract::Salmonella is a major pathogen that causes acute foodborne outbreaks worldwide. Seafood, particularly shellfish, is a proven source of Salmonella spp. infection because many people prefer to eat it raw or lightly cooked. However, traditional identification methods are too time-consuming and complex to detect contamina...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-018-1895-2

    authors: Gao W,Huang H,Zhu P,Yan X,Fan J,Jiang J,Xu J

    更新日期:2018-05-01 00:00:00

  • Quantitative analysis of hydrogen peroxide with special emphasis on biosensors.

    abstract::Determination of hydrogen peroxide (H2O2) has become essential in pharmaceutical, biological, clinical and environmental studies. The conventional detection methods of H2O2 such as colourimetry, titration, chromatography, spectrophotometry, fluorimetry, chemiluminescence have limited success, due to their poor selecti...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章,评审

    doi:10.1007/s00449-017-1878-8

    authors: Pundir CS,Deswal R,Narwal V

    更新日期:2018-03-01 00:00:00

  • Effect of pH on the metabolic flux of Klebsiella oxytoca producing 2,3-butanediol in continuous cultures at different dilution rates.

    abstract::The efficiency of the bioconversion process and the achievable end-product concentration decides the economic feasibility of microbial 2,3-butanediol (2,3-BDO) production. In 2,3-BDO production, optimization of culture condition is required for cell growth and metabolism. Also, the pH is an important factor that influ...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-013-0932-4

    authors: Park C,Lu M,Yun S,Park K,Lee J

    更新日期:2013-06-01 00:00:00

  • Metabolic engineering of Corynebacterium glutamicum to produce GDP-L-fucose from glucose and mannose.

    abstract::Wild-type Corynebacterium glutamicum was metabolically engineered to convert glucose and mannose into guanosine 5'-diphosphate (GDP)-L-fucose, a precursor of fucosyl-oligosaccharides, which are involved in various biological and pathological functions. This was done by introducing the gmd and wcaG genes of Escherichia...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-013-0900-z

    authors: Chin YW,Park JB,Park YC,Kim KH,Seo JH

    更新日期:2013-06-01 00:00:00

  • Biological nitrogen and phosphorus removal in membrane bioreactors: model development and parameter estimation.

    abstract::Membrane bioreactors (MBR) are being increasingly used for wastewater treatment. Mathematical modeling of MBR systems plays a key role in order to better explain their characteristics. Several MBR models have been presented in the literature focusing on different aspects: biological models, models which include solubl...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-012-0806-1

    authors: Cosenza A,Mannina G,Neumann MB,Viviani G,Vanrolleghem PA

    更新日期:2013-04-01 00:00:00

  • Optical device for parallel online measurement of dissolved oxygen and pH in shake flask cultures.

    abstract::We describe a new device with parallel optical measurement of dissolved oxygen (DO) and pH in up to nine shake flasks applicable in any conventional shaking incubator. Measurement ranges are 0-500% of air saturation for oxygen and 5.5-8.5 for pH. It was used to characterize growth profiles of different L-lysine produc...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-009-0367-0

    authors: Schneider K,Schütz V,John GT,Heinzle E

    更新日期:2010-06-01 00:00:00

  • Characterization of Pb2+ biosorption from aqueous solution by Rhodotorula glutinis.

    abstract::The yeast Rhodotorula glutinis was examined for its ability to remove Pb(2+) from aqueous solution. Within 10 min of contact, Pb(2+) sorption reached nearly 80% of the total Pb(2+) sorption. The optimum initial pH value for removal of Pb(2+ )was 4.5-5.0. The percentage sorption increased steeply with the biomass conce...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-002-0315-8

    authors: Cho DH,Kim EY

    更新日期:2003-03-01 00:00:00

  • Immobilized L-aspartate ammonia-lyase from Bacillus sp. YM55-1 as biocatalyst for highly concentrated L-aspartate synthesis.

    abstract::L-aspartate ammonia-lyase from Bacillus sp. YM55-1 (AspB, EC 4.3.1.1) catalyzes the reversible conversion of L-aspartate (Asp) into fumarate and ammonia with a high specific activity toward the substrate. AspB was expressed in Escherichia coli and partially purified by heat precipitation and saturation with ammonium s...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-012-0732-2

    authors: Cárdenas-Fernández M,López C,Alvaro G,López-Santín J

    更新日期:2012-10-01 00:00:00

  • Exploring the potential of halotolerant bacteria for biodegradation of polycyclic aromatic hydrocarbon.

    abstract::The present study aimed to determine the degradation and transformation of three-ring PAHs phenanthrene and anthracene by Cryptococcus sp. MR22 and Halomonas sp. BR04 under halophilic conditions. The growth progress of Cryptococcus sp. MR22 and Halomonas sp. BR04 on anthracene and phenanthrene was monitored by colony-...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-020-02415-4

    authors: Al Farraj DA,Hadibarata T,Yuniarto A,Alkufeidy RM,Alshammari MK,Syafiuddin A

    更新日期:2020-12-01 00:00:00

  • Reverse-flow strategy in biofilters treating CS₂ emissions.

    abstract::The bacteriostatic properties of carbon disulphide (CS₂) hamper its biodegradation in conventional biofilters. The response of four biofilters operating in downflow mode and reverse-flow mode was compared in a laboratory-scale plant treating CS₂ under sudden short-term changes in operating conditions. A process shutdo...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-012-0795-0

    authors: Rojo N,Gallastegui G,Gurtubay L,Barona A,Elías A

    更新日期:2013-04-01 00:00:00

  • Biomimetic oxidase sensor based on functionalized surface of carbon nanotubes and iron prophyrins for catechol detection.

    abstract::A novel and highly stable biomimetic oxidase sensor system was designed for catehol detection. FePP used as biomimetic horseradish peroxidase (HRP) was immobilized onto modified multi-walled carbon nanotubes (MWCNTs). Functional groups such as -OH, -NH2 and -COOH were introduced onto the surface of MWCNTs to provide b...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-018-2032-y

    authors: Bin Z,Yanhong C,Jiaojiao X

    更新日期:2019-02-01 00:00:00

  • Probing control of glucose feeding in Vibrio cholerae cultivations.

    abstract::Infection with Vibrio cholerae is a significant problem in many developing countries. Cultivation of V. cholerae is used in production of cholera toxin B subunit, which is a component in a cholera vaccine. Fed-batch cultivations with V. cholerae in defined media have been conducted and reproducible results were obtain...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-002-0304-y

    authors: de Maré L,Andersson L,Hagander P

    更新日期:2003-01-01 00:00:00

  • Online filtering of CO2 signals from a bioreactor gas outflow using a committee of constructive neural networks.

    abstract::This work proposes a committee of Cascade Correlation neural networks as an online smoother for random measurement noise. The goals of this paper are twofold: first it intends to explore the possibilities of using a constructive neural network algorithm to learn how to filter typical noisy data from a bioreactor, CO(2...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-007-0152-x

    authors: Giordano RC,Bertini JR Jr,Nicoletti MC,Giordano RL

    更新日期:2008-02-01 00:00:00

  • A novel serine alkaline protease from Bacillus altitudinis GVC11 and its application as a dehairing agent.

    abstract::A serine alkaline protease from a newly isolated alkaliphilic Bacillus altitudinis GVC11 was purified and characterized. The enzyme was purified to homogeneity by acetone precipitation, DEAE-cellulose anion exchange chromatography with 7.03-fold increase in specific activity and 15.25% recovery. The molecular weight o...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-010-0483-x

    authors: Vijay Kumar E,Srijana M,Kiran Kumar K,Harikrishna N,Reddy G

    更新日期:2011-05-01 00:00:00

  • Recombinant biosynthesis of bacterial cellulose in genetically modified Escherichia coli.

    abstract::Bacterial cellulose (BC) exhibits unique properties such as high purity compared to plant-based cellulose; however, commercial production of BC has remained a challenge, primarily due to the strain properties of cellulose-producing bacteria. Herein, we developed a functional and stable BC production system in genetica...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-017-1864-1

    authors: Buldum G,Bismarck A,Mantalaris A

    更新日期:2018-02-01 00:00:00

  • Highly selective resonance scattering detection of trace thrombin using aptamer-modified AuRe nanoprobe.

    abstract::The gold-rhenium (AuRe) composite nanoparticle was prepared by NaBH(4) reduction procedure, and was modified by the aptamer to obtain an AuRe nanoprobe (AuRessDNA) for thrombin. In pH 7.0 Tris-HCl buffer solution and in the presence of salt, the nanoprobe specifically combined with thrombin to form AuRe-aptamer-thromb...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-010-0434-6

    authors: Liang A,Li J,Jiang C,Jiang Z

    更新日期:2010-11-01 00:00:00

  • Impact of operating conditions on performance of a novel gas double-dynamic solid-state fermentation bioreactor (GDSFB).

    abstract::A self-designed novel solid-state fermentation (SSF) bioreactor named "gas double-dynamic solid-state fermentation bioreactor (GDSFB)" showed great success in processes for the production of several valuable products. For the present study, a simple GDSFB (2 L in volume) was designed to investigate the impact of exhau...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-013-0950-2

    authors: Chen H,Li Y,Xu F

    更新日期:2013-11-01 00:00:00

  • Characterization of mixing and yield stress of pretreated wheat straw slurries used for the production of biofuels through tomography technique.

    abstract::Wheat straw is a low-cost feedstock for the production of biofuel. Pretreatment process is an important stage in producing biofuels since it makes the fibers more accessible to enzymatic hydrolysis which is the final step of producing biofuels. Pretreated wheat straw (PWS) slurries are non-Newtonian fluids with yield ...

    journal_title:Bioprocess and biosystems engineering

    pub_type: 杂志文章

    doi:10.1007/s00449-018-1959-3

    authors: Naghavi-Anaraki Y,Turcotte G,Ein-Mozaffari F

    更新日期:2018-09-01 00:00:00