Progesterone inhibition of sexual behavior is accompanied by an activation of aggression in female Syrian hamsters.

Abstract:

:Previous studies have shown that progesterone can have biphasic activational and inhibitory roles in the regulation of sexual behavior in female Syrian hamsters. The purpose of this study was to determine whether these biphasic effects on sexual behavior are mirrored in a reciprocal regulation of aggression. Ovariectomized female Syrian hamsters were treated with estradiol followed 2 and 3 days later by either 1) two oil injections (O-O), 2) an oil and a progesterone injection (O-P), 3) a progesterone and oil injection (P-O), or 4) two progesterone injections (P-P). Females were tested for aggression and sexual behavior in conjunction with these hormone treatments. On the final test session, P-P females had significantly lower lordosis durations than did O-P females, confirming the progesterone inhibition of sexual behavior previously reported. Without hormone treatment all females showed high baseline levels of aggression. On the last behavioral test, aggression in O-O females and P-O females was comparable to their baseline levels of aggression. In contrast, aggression in P-P females was significantly higher than the baseline levels of aggression. These results suggest that like its effects on sexual behavior, progesterone can have both inhibitory and activational effects on aggression in female Syrian hamsters.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Meisel RL,Sterner MR

doi

10.1016/0031-9384(90)90102-a

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

415-7

issue

3

eissn

0031-9384

issn

1873-507X

pii

0031-9384(90)90102-A

journal_volume

47

pub_type

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