Individual variation in locomotor behavior and maximal oxygen consumption in mice.


:Individual differences in open-field activity and emotionality (number of defecations and urinations), voluntary wheel running, voluntary and forced maximal sprint running speed on a photocell-timed racetrack, swimming endurance, and maximal oxygen consumption (VO2max) were studied in 35 random bred male ICR mice. With the exception of latency in the open field and voluntary speed on a racetrack, all measurements were significantly repeatable on two successive trial days. Maximal oxygen consumption (corrected for body size) was positively correlated with amount of wheel running during each day of a 7-day test, and the correlation became stronger throughout the testing period; however, none of the daily correlations reached statistical significance. The first factor from a principal components (PC) analysis showed positive loadings (component correlations) for all measures of speed in the open field, for both voluntary and forced maximal speeds on the racetrack, and for VO2max, but a negative loading for emotionality. Wheel running and VO2max loaded positively on PC 2. Only swimming endurance loaded strongly on PC 3; this trait was uncorrelated with any other measure of physiology or behavior. These results suggest that measures of both voluntary and forced locomotor speed, as well as amount of voluntary wheel running, may be related to aerobic physiological capacities in untrained mice.


Physiol Behav


Physiology & behavior


Friedman WA,Garland T Jr,Dohm MR




Has Abstract


1992-07-01 00:00:00














  • Influence of photoperiod, green food, and water availability on reproduction in male California mice (Peromyscus californicus).

    abstract::California mice (Peromyscus californicus) breed primarily during the winter rainy season and generally terminate breeding during the dry summer months. This pattern of reproduction could be regulated by day length, availability of green vegetation, or water availability. The effects of photoperiod and green vegetation...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Nelson RJ,Gubernick DJ,Blom JM

    更新日期:1995-06-01 00:00:00

  • The effect of alloxan-induced diabetes on triamine lesions in the ventromedial hypothalamus.

    abstract::It has been demonstrated that the ventromedial hypothalamus (VMH) of alloxan-induced diabetic mice is protected from subsequent gold thioglucose (GTG)-induced lesions. Another compound, 3,3'-methyliminobis-(N-methylpropylamine) (MIMPA), a triamine structurally unrelated to GTG, has been shown to cause similar VMH lesi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Brown DF,McGuirk JP,Larsen SP,Minter SD

    更新日期:1991-01-01 00:00:00

  • Contribution of spontaneous activity to daily energy expenditure of adult obese and lean Zucker rats.

    abstract::The contribution of somatomotor activity to daily energy expenditure was estimated in 10-month-old, weight-stable, obese (fa/fa) and lean (Fa/?) Zucker rats. Total and resting heat production were assessed by recording oxygen consumption and stabilimeter activity each minute for five consecutive days in free-feeding a...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Keesey RE,Swiergiel AH,Corbett SW

    更新日期:1990-08-01 00:00:00

  • Cognitive function in outbred house mice after 22 weeks of drinking oxygenated water.

    abstract::Oxygen-enriched drinking water, which is increasingly sold worldwide, is claimed to "keep both the body and the mind healthy." However, currently there is no scientific evidence for such a statement. Therefore, we assessed the effect of 22 weeks of drinking oxygenated water on cognitive performance in healthy mice, us...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Sommer AM,Bogusch C,Lerchl A

    更新日期:2007-05-16 00:00:00

  • Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats.

    abstract::The objective of this study was to examine the effect of chronic dietary restriction on the physical characteristics of the intestine and gut-derived satiety hormone production. Male Wistar rats (8 weeks) were randomized to ad libitum (AL) or 35% dietary restriction (DR) for 5 months. At the end of the study, physical...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Reimer RA,Maurer AD,Lau DC,Auer RN

    更新日期:2010-04-19 00:00:00

  • Long-term recordings from afferent taste fibers.

    abstract::The receptor cells of taste buds have a life span of about 10 days but it is not known if response characteristics of these receptors alter during the turnover cycle. To examine taste cell responses over time, a micromachined polyimide sieve electrode array was implanted between the cut ends of the rat chorda tympani ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Shimatani Y,Nikles SA,Najafi K,Bradley RM

    更新日期:2003-11-01 00:00:00

  • Effect of food restriction on acquisition and expression of a conditioned odor discrimination in mice.

    abstract::Level of food restriction was manipulated in mice to assess its importance for the acquisition and expression of a conditioned odor discrimination. In training, animals were exposed to odors (either rose or lemon) presented on a piece of filter paper in a pot covered in bedding. For half of the conditioning trials, gr...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Forestell CA,Schellinck HM,Boudreau SE,LoLordo VM

    更新日期:2001-03-01 00:00:00

  • Relative hedonic value modulates anticipatory contrast.

    abstract::Intake of an initial substance (e.g., 0.15% saccharin) is suppressed when the presentation of this substance precedes the availability of a preferred solution (e.g., 32% sucrose) in brief daily pairings. The present experiments show that degree of this anticipatory contrast effect is related to the relative hedonic va...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Flaherty CF,Turovsky J,Krauss KL

    更新日期:1994-06-01 00:00:00

  • Potentiation of panic-like behaviors of the rat by subconvulsive doses of strychnine.

    abstract::The present study was carried out to determine possible panicogenic effects of strychnine administered in subconvulsive doses to rats. Two experiments were conducted to assess two major features of panic in animal models: panic-related flight (through the observation of wild running [WR]) and defensive fights. In the ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: de Paula HM,Hoshino K

    更新日期:2004-01-01 00:00:00

  • Changes in the sexual behavior and testosterone levels of male rats in response to daily interactions with estrus females.

    abstract::Male rat sexual behavior has been intensively studied over the past 100 years, but few studies have examined how sexual behavior changes over the course of several days of interactions. In this experiment, adult male rats in the experimental group (n=12) were given daily access to estrus females for 30 min per day for...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Shulman LM,Spritzer MD

    更新日期:2014-06-22 00:00:00

  • Diurnal rhythms of body temperature, drinking and activity over reproductive cycles.

    abstract::These studies describe diurnal rhythm changes in female rats during gestation and lactation. In Experiment I, we measured the diurnal temperature rhythm (DTR) of 20 females through gestation, lactation and the post-lactational period and found that rhythm amplitude decreased during gestation and increased during lacta...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Kittrell EM,Satinoff E

    更新日期:1988-01-01 00:00:00

  • Development of a "pure-tactile" assessment of edge discrimination in the hands and oral cavity.

    abstract::Oral cavity edge perception acuity relative to the fingertip has previously been evaluated by the utilization of cognitively-loaded, stereognostic methods. However, with the lack of connection of the tongue to the visual association cortex, there is concern the superior acuity of the fingertip may be attributable to t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Miles BL,Ang SL,Simons CT

    更新日期:2020-10-01 00:00:00

  • Fructo-oligosaccharides reduce energy intake but do not affect adiposity in rats fed a low-fat diet but increase energy intake and reduce fat mass in rats fed a high-fat diet.

    abstract::The ingestion of low or high lipid diets enriched with fructo-oligosaccharide (FOS) affects energy homeostasis. Ingesting protein diets also induces a depression of energy intake and decreases body weight. The goal of this study was to investigate the ability of FOS, combined or not with a high level of protein (P), t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Hadri Z,Rasoamanana R,Fromentin G,Azzout-Marniche D,Even PC,Gaudichon C,Darcel N,Bouras AD,Tomé D,Chaumontet C

    更新日期:2017-12-01 00:00:00

  • Auditory potentials elicited by the grass photic stimulator in the rat.

    abstract::Flash visual evoked potentials were recorded from the rat to determine whether the Grass photic stimulator could generate an auditory component of the waveform. When the click associated with each lamp flash remained unmuffled, the primary response of the visual cortex (P30) was preceded by an earlier positivity with ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Shaw NA

    更新日期:1992-08-01 00:00:00

  • The effect of active hypohydration on cognitive function: A systematic review and meta-analysis.

    abstract::Hypohydration is generally considered to have a negative effect on cognitive function, despite several studies reporting comparable findings between hydration states. Recommendations to avoid moderate dehydration (≥ 2% loss in body mass) are commonly made to athletes, on the provision that this deficit may impair opti...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,meta分析


    authors: Goodman SPJ,Moreland AT,Marino FE

    更新日期:2019-05-15 00:00:00

  • The protein synthesis inhibitor anisomycin reduces sex behavior during a critical period after testosterone treatment in male Syrian hamsters.

    abstract::Testosterone (T) is critical for maintaining male sexual behavior (MSB) in rodents, in part by altering protein synthesis in a well-defined neural circuit. The specific timing of protein synthesis essential for expression of MSB has never been investigated. We administered the protein synthesis inhibitor anisomycin (A...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Piekarski DJ,Seto T,Zucker I

    更新日期:2012-01-18 00:00:00

  • Chronic social defeat, but not restraint stress, alters bladder function in mice.

    abstract:BACKGROUND:Voiding disorders in humans, particularly in children are associated with increased incidence of behavioral issues as well as past history of childhood abuse. We hypothesized that creating stress in mice, utilizing either a chronic social defeat model (SD) or restraint stress in shallow water model (RSSW) wo...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Mann EA,Alam Z,Hufgard JR,Mogle M,Williams MT,Vorhees CV,Reddy P

    更新日期:2015-10-15 00:00:00

  • Estradiol decreases the orexigenic effect of melanin-concentrating hormone in ovariectomized rats.

    abstract::Estradiol exerts an inhibitory effect on food intake via interactions with anorexigenic peptides, like cholecystokinin, that function to decrease meal size. It is currently unknown whether estradiol also interacts with orexigenic compounds implicated in the physiological control of food intake. Thus, the primary goal ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Messina MM,Boersma G,Overton JM,Eckel LA

    更新日期:2006-07-30 00:00:00

  • Changes in hippocampal rhythmic slow activity during instrumental cardiovascular conditioning in the monkey (Macaca mulatta).

    abstract::Analyses of 4-8 Hz electrical activity (RSA) of the mid-ventral hippocampus, motor activity (M), and blood pressure were carried out during experiments in which three monkeys were operantly conditioned to slow heart rate (HR), to speed HR or during control, no feedback (FB) periods. The results showed that RSA activit...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Joseph JA,Quilter RE,Engel BT

    更新日期:1982-04-01 00:00:00

  • Lack of sex and estrous cycle effects on the activity of three antioxidant enzymes in rats.

    abstract::The activity of antioxidant enzymes was investigated in red blood cells of male and female Wistar rats 3-4 months of age. Superoxide dismutase (EC, catalase (EC, and glutathione peroxidase (EC did not show any significant variation in the different phases of the estrous cycle. No differen...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: D'Almeida V,Hipólide DC,da Silva-Fernandes ME

    更新日期:1995-02-01 00:00:00

  • How to quench your thirst. The effect of water-based products varying in temperature and texture, flavour, and sugar content on thirst.

    abstract::The sensation of thirst plays an important role in the consumption of water or other fluids to rehydrate the body in order to keep bodily functions working properly. An increase in saliva secretion, wetting the mouth by ingestion of liquids, and cooling and sour components in products can alleviate this sensation alre...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: van Belzen L,Postma EM,Boesveldt S

    更新日期:2017-10-15 00:00:00

  • Kissing reduces allergic skin wheal responses and plasma neurotrophin levels.

    abstract::The effect of kissing on allergen-induced skin wheal responses and plasma neurotrophin levels were studied in 30 normal subjects, 30 patients with allergic rhinitis (AR), and 30 patients with atopic dermatitis (AD). All of the patients with AR or AD are allergic to house dust mite (HDM) and Japanese cedar pollen (JCP)...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Kimata H

    更新日期:2003-11-01 00:00:00

  • Sex differences in oxidant/antioxidant balance under a chronic mild stress regime.

    abstract::The deterioration of homeostasis between oxidant/antioxidant species may represent an important mechanism linking psychological stress to cardiovascular risk despite the many sex differences in stress responsiveness. The goal of the present study was to investigate the influence of chronic mild stress (CMS), a widely ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Kamper EF,Chatzigeorgiou A,Tsimpoukidi O,Kamper M,Dalla C,Pitychoutis PM,Papadopoulou-Daifoti Z

    更新日期:2009-08-04 00:00:00

  • Pharmacological versus sensory factors in the satiation of chocolate craving.

    abstract::This is the first experimental study directed at differentiating between physiological or sensory accounts of the satiation of nondrug cravings, using chocolate craving, the most common craving in North America. At the onset of craving, chocolate cravers consumed a chocolate bar, the caloric equivalent in "white choco...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Michener W,Rozin P

    更新日期:1994-09-01 00:00:00

  • Aging effects on elevated plus maze behavior in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley male and female rats.

    abstract::Male and female spontaneously hypertensive (SHR), Wistar-Kyoto (WKY), and Sprague-Dawley (SD) rats were assessed at one of two ages (postnatal day 74 or 346) for open field locomotor activity and anxiety-related behavior in the elevated plus maze (EPM). In general, the SHR displayed the least anxiety-related behavior,...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Ferguson SA,Gray EP

    更新日期:2005-08-07 00:00:00

  • Effect of diet consistency, taste and calories on food intake of weanling rats with dorsomedial hypothalamic lesions.

    abstract::Male weanling Sprague-Dawley rats with dorsomedial hypothalamic lesions (DMNL rats) primarily destroying the dorosomedial hypothalamic nuclei (DMN) showed significant hypophagia on lab chow chunks compared to sham-operated controls. When given a choice between lab chow in the form of chunks or powder, both controls an...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Bernardis LL,Bellinger LL

    更新日期:1977-08-01 00:00:00

  • Gender-based eye movement differences in passive indoor picture viewing: An eye-tracking study.

    abstract::Male and female brains have different structures, which can make genders produce various eye- movement patterns. This study presents the results of an eye tracking experiment in which we analyzed the eye movements of 25 male and 20 female participants during passive indoor picture viewing. We examined eye-movement par...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Abdi Sargezeh B,Tavakoli N,Daliri MR

    更新日期:2019-07-01 00:00:00

  • Comparing interval and continuous exercise training regimens on neurotrophic factors in rat brain.

    abstract::The research literature suggests that oxidative stress and pro-inflammatory factors influence neurotrophins in vitro. However, there is insufficient information about their effects on exercise training conditions, especially during high intensity trainings. This study aimed to compare the effects of 6weeks of high int...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Afzalpour ME,Chadorneshin HT,Foadoddini M,Eivari HA

    更新日期:2015-08-01 00:00:00

  • Beta-endorphin-like immunoreactivity levels in the hypothalamus, the periaqueductal grey and the pituitary of the DBA mouse: determination by ELISA and relationship to nociception.

    abstract::The present paper describes the development and application of an enzyme-linked immunosorbent assay (ELISA) for the assessment of beta-endorphin-like immunoreactivity (beta-ELIR) level in the hypothalamus, the periaqueductal grey (PAG) and the pituitary of DBA/2 mice that were subjected to mild social stress (aggressi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Külling P,Siegfried B,Frischknecht HR,Messiha FS,Pasi A

    更新日期:1989-07-01 00:00:00

  • Selective hepatic vagotomy blocks pancreatic glucagon's satiety effect.

    abstract::To test the hypothesis that hepatic vagal afferents mediate the satiety effect of pancreatic glucagon, we tested the effects of selective surgical and pharmacological lesions of the abdominal vagus on glucagon's potency to inhibit feeding. Surgical disconnection of only the hepatic branch of the abdominal vagus blocke...

    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Geary N,Smith GP

    更新日期:1983-09-01 00:00:00