Psychophysiological stress responses in amputees with and without phantom limb pain.

Abstract:

:The present experiment tested the hypothesis that phantom limb pain amputees show a different pattern of psychophysiological reactivity to stress compared with painfree amputees. Six phantom limb pain (PLP) and five painfree upper-extremity amputees were administered two groups of tasks: stressful and relaxing. The measured dependent variables were skin temperature recorded at both stump and intact site, heart rate, blood pressure, subjective pain and stress ratings. Phantom limb pain patients were characterized by higher stump temperature compared with phantom limb painfree patients. This effect was observed during the whole recording. Consistently with the between-subjects effect, when PLP patients exhibited higher skin temperature (during relaxation, compared with during stressful tasks), they perceived more pain. The experiment showed higher cardiovascular reactivity in PLP patients, specifically to the stressful free-speech task, which focused on recollection of the amputation event. As compared with the painfree patients, during the personal stressor, PLP patients' heart rate and systolic blood pressure increased, indicating a greater sympathetic response. Results indicate that peripheral factors, such as stump temperature reliably differentiate PLP from painfree patients. Moreover, the clear cardiovascular hyperreactivity observed in PLP patients during their report of amputation suggests that PLP is associated with a long-term emotional memory for the painful experience of that event. These results are consistent with most reports in the literature relating phantom pain development to the experience of preamputation pain.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Angrilli A,Köster U

doi

10.1016/s0031-9384(99)00235-8

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

699-706

issue

5

eissn

0031-9384

issn

1873-507X

pii

S0031938499002358

journal_volume

68

pub_type

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