Abstract：
:Radiologic accidents or terrorist acts involving radioactive material, as well as radiation exposure in medical or industrial procedures are potential sources of risk for human health. All these risks share a common element, exposure to ionizing radiation. The extent of ionizing radiation injury will depend on a number of independent variables such as dose, type of radiation and tissue, etc. As a result of ionizing radiation exposure, biological effects can take place in acute or long-term manner. As in the case of other self-renewing tissues (e.g. hematopoietic system and intestinal epithelium), skin is also extremely sensitive to ionizing radiation. In this way, appropriate management of radiation skin effects might improve the therapeutic benefit of medical radiation therapy, as well as reduce the mortality associated with any radiological incident (e.g. accident or terrorist attack). For this reason, current and potential future treatment approaches for skin radiation injury are reviewed in this work. Unfortunately, there is no sufficient evidence for establishing a standard treatment to prevent or mitigate radiation-induced cutaneous injury. Thus, continued research is necessary to achieve effective therapies to address this important health problem.
journal_name
Int J Radiat Bioljournal_title
International journal of radiation biologyauthors
Soriano JL,Calpena AC,Souto EB,Clares Bdoi
10.1080/09553002.2019.1562254keywords:
["Ionizing radiation","acute effects","late effects","review","skin","treatment"]subject
Has Abstractpub_date
2019-05-01 00:00:00pages
537-553issue
5eissn
0955-3002issn
1362-3095journal_volume
95pub_type
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