Regulation of molecular pathways in ischemia-reperfusion injury after liver transplantation.

abstract：BACKGROUND:The management of small bowel transplantation is unique because signs of rejection can be obtained visually by endoscopy. The aim of this study was to evaluate the accuracy of endoscopic appearance in assessing histologic evidence of acute cellular rejection (ACR). METHODS:Endoscopies were performed in 66 a...

journal_title：Transplantation

authors： O'Keefe SJ,El Hajj II,Wu T,Martin D,Mohammed K,Abu-Elmagd K

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:It is unclear if the category of acute rejection with intimal arteritis (ARV) is relevant to short- and long-term clinical outcomes and if the graft outcomes are affected by the severity of intimal arteritis. METHODS:One hundred forty-eight ARV episodes were reviewed and categorized according to the 2013 Ba...

journal_title：Transplantation

authors： Wu K,Budde K,Schmidt D,Neumayer HH,Rudolph B

更新日期：2015-08-01 00:00:00

abstract：:Limited recovery of contractile function and loss of coronary reactivity have been observed following prolonged hypothermic storage and transplantation of the heart. Since lipid peroxidation has a significant role in these deficits, we investigated the cardioprotective effects of a 21-aminosteroid. U74389G, 3 mg/kg i....

journal_title：Transplantation

authors： Duguay P,Chen H,Daloze P,Dumont L

更新日期：1996-04-15 00:00:00

abstract：:The requirement for effective, minimally toxic immunosuppression remains a major obstacle to performing human composite tissue allotransplantation. The skin component of composite tissue (e.g., limb) allografts is especially antigenic, necessitating toxic immunosuppressant doses to prevent or reverse acute rejection. ...

journal_title：Transplantation

authors： van den Helder TB,Benhaim P,Anthony JP,McCalmont TH,Mathes SJ

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) is still a common complication, the prognosis of kidney function after liver transplantation (LT) is not well known. Moreover, kidney function after LT in children with renal involvement is unknown. METHODS:We retrospectively analyzed patients aged <20 years who underwe...

journal_title：Transplantation

authors： Sato M,Kaneko T,Ogura M,Kamei K,Ito S,Fukuda A,Sakamoto S,Kasahara M,Ishikura K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The hepatic arteries (HAs) in a hepatic graft are usually reconstructed using the recipient's left or right HAs in living donor liver transplantation (LDLT). There have been no apparent selection criteria concerning which of the recipient's HAs should be used. This study retrospectively investigated whether ...

journal_title：Transplantation

authors： Uchiyama H,Ikegami T,Soejima Y,Ninomiya M,Kayashima H,Taketomi A,Shirabe K,Maehara Y

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:IgG antibodies to HLA class I antigens can cause hyperacute rejection of renal allografts. Screening of sera from such transplant candidates is laborious, time-consuming, and expensive when performed by sensitive antihuman globulin-augmented lymphocytotoxicity (AHG-CDC). METHODS:Because 60-70% of our transp...

journal_title：Transplantation

authors： Moore SB,Ploeger NA,DeGoey SR

更新日期：1997-12-15 00:00:00

abstract：:Vascularized xenografts are rejected acutely and hyperacutely in concordant or discordant combinations, respectively. We investigated the impact of the donor-recipient combination on the rejection of arterial xenografts, analyzing the cellular and extracellular matricial compartments. Aortic xenografts were performed ...

journal_title：Transplantation

authors： Allaire E,Mandet C,Bruneval P,Bensenane S,Becquemin JP,Michel JB

更新日期：1996-09-27 00:00:00

abstract：BACKGROUND:Anti-thymocyte globulin (ATG) is used frequently as induction therapy in renal transplant recipients. It has been standard practice that the various polyclonal anti-lymphocyte preparations be administered via central line, vascular shunt, or arteriovenous fistula to avoid thrombophlebitis. METHODS:We have s...

journal_title：Transplantation

authors： Rahman GF,Hardy MA,Cohen DJ

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:A recent proposal supports the elimination of allocation points for human leukocyte antigen (HLA) mismatches (MM) in cadaveric kidney transplantation. The intent is to increase access for some racial groups that might be disadvantaged by the representation of race-specific HLA in a largely white donor pool. ...

journal_title：Transplantation

authors： Rebellato LM,Arnold AN,Bozik KM,Haisch CE

更新日期：2002-12-15 00:00:00

abstract：BACKGROUND:The prevalence of renal posttransplantation amputation and its impact on allograft and patient survival have not been widely reported. METHODS:We used an incident cohort of patients who underwent renal transplantation between June 2004 and September 2009. Amputation data were obtained using Medicare institu...

journal_title：Transplantation

authors： Brar A,Jindal RM,Sumrani N,John D,Mondal Z,Tedla F,Salifu MO

更新日期：2013-05-27 00:00:00

abstract：BACKGROUND:Generation of non-human primate regulatory T cells (Treg) with alloantigen (alloAg) specificity would allow their testing in preclinical transplant models. Low recovery of Treg from peripheral blood limits their potential utility. In small animals and humans, conventional myeloid dendritic cells (DC) have be...

journal_title：Transplantation

authors： Zahorchak AF,Raimondi G,Thomson AW

更新日期：2009-11-15 00:00:00

abstract：BACKGROUND:Intrathymic events undergoing allograft rejection remain undefined. The present study investigated the role of tumor necrosis factor-beta on acute thymic involution in rat hepatic allograft recipients during rejection. METHODS:Apoptosis and cellular phenotypic changes in the thymus were studied after hepati...

journal_title：Transplantation

authors： Yamaguchi Y,Okabe K,Miyanari N,Matsumura F,Ichiguchi O,Akizuki E,Matsuda T,Liang J,Ohshiro H,Miyayama Y,Yamada S,Mori K,Ogawa M

更新日期：1998-10-15 00:00:00

abstract：:T lymphocyte subsets, mitogenic response, and immunoglobulin levels were studied in peripheral blood from 95 thalassemic patients before and at different times after bone marrow transplantation. With the exception of patients receiving more than 100 transfusion units before transplant, who showed an increased percenta...

journal_title：Transplantation

authors： Andreani M,Centis F,Lucarelli G,Polchi P,Rossi MC,La Nasa G,De Biagi M

更新日期：1988-09-01 00:00:00

abstract：:We recently reported that reconstitution of lethally irradiated B10 mouse recipients with 40 x 10(6) untreated WF rat bone marrow cells resulted in stable fully xenogeneic chimerism (WF rat----B10 mouse). In these animals, the tolerance induced for skin xenografts was highly MHC specific in that donor-specific WF rat ...

journal_title：Transplantation

authors： Zeng YJ,Ricordi C,Tzakis A,Rilo HL,Carroll PB,Starzl TE,Ildstad ST

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Although longer pretransplant dialysis has been associated with poor kidney transplant outcome, no data about this association exist from the current era or from Europe. We studied the association of pretransplant dialysis duration on outcomes after kidney transplantation across two different time periods. ...

journal_title：Transplantation

authors： Helanterä I,Salmela K,Kyllönen L,Koskinen P,Grönhagen-Riska C,Finne P

更新日期：2014-08-27 00:00:00

abstract：INTRODUCTION:The purpose of the current study was to investigate the capacity of CD4+, CD8+, or non-T cells to independently initiate acute rejection of allogeneic hepatocytes using reconstituted SCID, CD4 or CD8 knockout (KO) recipient mice. METHODS:Allogeneic hepatocytes (FVB/N, H-2q) were transplanted into C57BL/6....

journal_title：Transplantation

authors： Bumgardner GL,Gao D,Li J,Baskin JH,Heininger M,Orosz CG

更新日期：2000-12-27 00:00:00

abstract：:As a consequence of its large volume, a microencapsulated islet graft can be implanted only into the peritoneal cavity. The graft volume can be reduced by using small capsules. However, reduction of the diameter of the capsules holds a certain risk, because with smaller capsules, more islets may be found to protrude f...

journal_title：Transplantation

authors： De Vos P,De Haan B,Pater J,Van Schilfgaarde R

更新日期：1996-10-15 00:00:00

abstract：:In 33 renal allograft recipient-donor pairs, B and T lymphocyte complement-dependent cytotoxicity crossmatches and mixed lymphocyte culture (MLC) blocking experiments were performed and the results were correlated with graft outcome. MLC blocking particularly in the unidirectional culture against donor-stimulating cel...

journal_title：Transplantation

authors： Ettenger RB,Opelz G,Walker J,Terasaki PI,Uittenbogaart C,Pennisi AJ,Malekzadeh MH,Fine RN

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation is a potentially curative therapy for many malignant and nonmalignant hematologic diseases. However, acute graft-versus-host disease (aGVHD) is a lethal complication of hematopoietic stem cell transplantation, which limits its application. Cytokines such as ...

journal_title：Transplantation

authors： Qian L,Mei K,Shen J,Cai J

更新日期：2013-03-15 00:00:00

abstract：:The aim of this study was to assess the efficacy of an enteral diet fortified with arginine, RNA, and fish oil (Impact), alone and in combination with cyclosporine (CsA) and donor-specific transfusion (DST) on allograft survival in the ACI:Lewis rat cardiac transplant model. Animals were fed ad libitum with either sta...

journal_title：Transplantation

authors： Levy AE,Alexander JW

更新日期：1995-10-27 00:00:00

abstract：:The aim of this study was to compare the extent of in vitro T cell depletion and recovery of hematopoietic progenitor cells achieved with five methods of T cell depletion. Bone marrow samples from the same source were treated with monoclonal antibody Campath-1 (CP1) and human complement, XomaZyme-H65 (anti-T cell rici...

journal_title：Transplantation

authors： Frame JN,Collins NH,Cartagena T,Waldmann H,O'Reilly RJ,Dupont B,Kernan NA

更新日期：1989-06-01 00:00:00

abstract：:Seventy-two dog kidneys were stored under hypothermia as described by Collins and Sacks between 24 and 72 hr and then transplanted. The immediate function of the kidneys was measured by p-aminohippuric acid and inulin clearances. Twenty-four hr proved to be the maximum safe preservation time with both methods. The imm...

journal_title：Transplantation

authors： Grundmann R,Strümper R,Eichmann J,Pichlmaier H

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Sensitization to human leukocyte antigens (HLA) is a significant barrier to transplantation. Currently, no proven therapy exists to improve access to transplantation for highly sensitized patients. Here, we report a novel approach using intravenous immune globulin to modulate anti-HLA antibody and improve th...

journal_title：Transplantation

authors： Jordan SC,Vo A,Bunnapradist S,Toyoda M,Peng A,Puliyanda D,Kamil E,Tyan D

更新日期：2003-08-27 00:00:00

abstract：:The benefits of cytomegalovirus (CMV) prophylaxis in preventing the direct effects of CMV infection and disease are well established; however, the impact of exposure to antiviral agents on preventing the indirect effects of CMV infection are poorly defined. This article reviews the results of current studies demonstra...

journal_title：Transplantation

authors： Pescovitz MD

更新日期：2006-07-27 00:00:00

abstract：:Brainstem death is associated with endocrine and metabolic alterations that can result in donor hemodynamic instability. It has been suggested that these changes can be reversed through hormonal manipulation of the donor. We measured thyroid hormone levels (free triiodothyronine [fT3], free tetraiodothyronine [fT4], r...

journal_title：Transplantation

authors： Karayalçin K,Umaña JP,Harrison JD,Buckels JA,McMaster P,Mayer AD

更新日期：1994-03-15 00:00:00

abstract：BACKGROUND:Injection of neonatal BALB/c mice with semi-allogeneic splenocytes leads to antigen-specific tolerance lasting into adulthood. Tolerant mice accept A/J skin grafts and fail to generate CD8 cytotoxic T lymphocyte (CTL) activity against A/J targets. Anergic CD8 T cells are present in tolerant mice, and CD4 reg...

journal_title：Transplantation

authors： Gao Q,Rouse TM,Kazmerzak K,Field EH

更新日期：1999-12-27 00:00:00

abstract：:Experiments were performed on the quality of renal functional recovery after 24, 48, or 72-hr hypothermic storage preservation of canine kidneys in Euro-Collins solution (EC), Collins' solution C2, hypertonic citrate solutions (HC, HC-D2O), or our new flush solution 2 (F.2). Clearance tests (inulin, paraaminohippuric ...

journal_title：Transplantation

authors： Fischer JH,Knupfer P,Beyer M

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Little is known about innate lymphoid cell (ILC) populations in the human gut, and the turnover of these cells and their subsets after transplantation has not been described. METHODS:Intestinal samples were taken from 4 isolated intestine and 3 multivisceral transplant recipients at the time of any operativ...

journal_title：Transplantation

authors： Weiner J,Zuber J,Shonts B,Yang S,Fu J,Martinez M,Farber DL,Kato T,Sykes M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:This study aimed to determine factors associated with body composition changes shortly after liver transplantation (LTx), including the influence of immunosuppressive agents. The combined resting energy expenditure (REE) and handgrip strength provided a valuable assessment in data interpretation of body comp...

journal_title：Transplantation

authors： Brito-Costa A,Pereira-da-Silva L,Papoila AL,Alves M,Mateus É,Nolasco F,Barroso E

更新日期：2016-08-01 00:00:00