Rhesus monkey immature monocyte-derived dendritic cells generate alloantigen-specific regulatory T cells from circulating CD4+CD127-/lo T cells.

abstract：:Ninety-eight renal transplant recipients who had been followed for 1-6.5 years (median 3.2 years) were reviewed to determine the effect of donor and recipient hepatitis B surface antigen status on the incidence of hepatitis and on patient survival. The cumulative risk of developing hepatitis posttransplant was signifi...

journal_title：Transplantation

authors： Chan PC,Lok AS,Cheng IK,Chan MK

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The piggyback technique of orthotopic liver transplantation is an attractive alternative that preserves the recipient inferior vena cava and allows uninterrupted venous blood return during the anhepatic phase. As with other transplantation techniques, the vascular anastomoses required by the piggyback techni...

journal_title：Transplantation

authors： Sze DY,Semba CP,Razavi MK,Kee ST,Dake MD

更新日期：1999-08-15 00:00:00

abstract：:We describe four patients who suffered asystole, myocardial infarction (in two cases) and supraventricular tachycardia at the time of high-dose methylprednisolone infusion. One patient died during infusion. We measured the effects of methylprednisolone and placebo infusion on heart rate, blood pressure, and cardiac ou...

journal_title：Transplantation

authors： Smith RS,Warren DJ

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:We previously reported the novel activity of alloprimed CD8 T cells that suppress posttransplant alloantibody production. The purpose of the study is to investigate the expression and role of CXCR5 on antibody-suppressor CD8 T-cell function. METHODS:C57BL/6 mice were transplanted with FVB/N hepatocytes. All...

journal_title：Transplantation

authors： Zimmerer JM,Ringwald BA,Elzein SM,Avila CL,Warren RT,Abdel-Rasoul M,Bumgardner GL

更新日期：2019-09-01 00:00:00

abstract：:Natural anti-carbohydrate antibodies are central to hyperacute rejection in ABO-incompatible allotransplantation and in discordant xenotransplantation. ABO-incompatible rejection has been inhibited successfully using intravenous soluble carbohydrates as antibody inhibitors. The approach has been less successful previo...

journal_title：Transplantation

authors： Cairns T,Lee J,Goldberg L,Cook T,Simpson P,Spackman D,Palmer A,Taube D

更新日期：1995-12-15 00:00:00

abstract：:Forty-three human liver allograft biopsies and normal liver were directly analyzed for inflammatory and immunoregulatory cytokine gene expression by polymerase chain reaction (PCR). IL-5 gene expression was predominantly present in biopsies from liver allografts with histopathological evidence of acute rejection. IL-2...

journal_title：Transplantation

authors： Martinez OM,Krams SM,Sterneck M,Villanueva JC,Falco DA,Ferrell LD,Lake J,Roberts JP,Ascher NL

更新日期：1992-02-01 00:00:00

abstract：:The results of OKT3 use for steroid-resistant rejection rescue in adult liver transplantation were analyzed retrospectively from a single transplant center. Comparison was made with concurrent patients who had no rejection (NR) or steroid-responsive rejections (SR). The records of 290 patients who underwent 323 liver ...

journal_title：Transplantation

authors： Solomon H,Gonwa TA,Mor E,Holman MJ,Gibbs J,Watemberg I,Netto G,Goldstein RM,Husberg BS,Klintmalm GB

更新日期：1993-01-01 00:00:00

abstract：:The primary effects of CsA on human lymphocyte responses in vitro appear to be the inhibition of IL-2 production and the inhibition of cytotoxic T cell activation. Induction of suppressor T cell activity is resistant to the effects of CsA. These data imply two distinct subsets of lymphocytes: CsA-resistant and CsA-sen...

journal_title：Transplantation

authors： Hess AD,Colombani PM

更新日期：1988-08-01 00:00:00

abstract：INTRODUCTION:The importance of HLA matching for renal transplantation outcomes has been appreciated for several decades. It has been hypothesized that as pharmacologic immunosuppression becomes stronger and more specific, the impact of HLA matching may be vanishing. Mycophenolate Mofetil (MMF) has been demonstrated to ...

journal_title：Transplantation

authors： Meier-Kriesche HU,Ojo AO,Leichtman AB,Magee JC,Rudich SM,Hanson JA,Cibrik DM,Kaplan B

更新日期：2001-02-15 00:00:00

abstract：:Hepatocyte transplantation (HT) has been performed in patients with liver-based metabolic disease and acute liver failure as a potential alternative to liver transplantation. The results are encouraging in genetic liver conditions where HT can replace the missing enzyme or protein. However, there are limitations to th...

journal_title：Transplantation

authors： Hughes RD,Mitry RR,Dhawan A

更新日期：2012-02-27 00:00:00

abstract：:Although extrinsic denervation is inevitable after intestinal transplantation and leads to poor intestinal function, little is known about the occurrence of extrinsic reinnervation. In this study, extrinsic sympathetic reinnervation was investigated morphologically following syngeneic intestinal transplantation perfor...

journal_title：Transplantation

authors： Kiyochi H,Ono A,Yamamoto N,Ohnishi K,Shimahara Y,Kobayashi N

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:Clinical and epidemiological data of pandemic influenza A H1N1 infection in solid-organ transplant recipients have been described, but scarce data compare these outcomes with nonimmunocompromised patients. METHODS:We retrospectively reviewed and compared the clinical presentation, morbidity, and mortality o...

journal_title：Transplantation

authors： Camargo LF,de Sandes-Freitas TV,Silva CD,Bittante CD,Ono G,Corrêa L,Silva M Jr,Bellei NC,Goto JM,Medeiros EA,Gomes PS,Medina-Pestana JO

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND:In a randomized, controlled study we investigated the clinical efficacy of the microemulsion formulation of cyclosporine (Neoral) in comparison with Sandimmune (SIM) in the treatment of patients who underwent primary orthotopic liver transplantation (OLT). METHODS:In total, 33 patients were randomized in a ...

journal_title：Transplantation

authors： Graziadei IW,Wiesner RH,Marotta PJ,Porayko MK,Dahlke LJ,Wilson SM,Steers JL,Krom RA

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:Liver transplantation is a widely accepted treatment for end-stage liver disease. The aim of our study was to investigate the imbalance between T helper type 17 (Th17) and CD4(+) CD25(+) Foxp3(+) regulatory T (Treg) cells during hepatic allograft rejection in a rodent grafts model because their roles in live...

journal_title：Transplantation

authors： Zhou Y,Yang X,Zhang H,Jiang J

更新日期：2015-06-01 00:00:00

abstract：:The immunosuppressive effects of leflunomide and cyclosporine were evaluated in a rat neurovascularized myocutaneous allograft model. Inbred Brown-Norway and Lewis rats were served as donors and recipients, respectively. All recipients were observed for 60 days or until allograft rejection occurred. All isograft contr...

journal_title：Transplantation

authors： Yeh LS,Gregory CR,Griffey SM,Lecouteur RA,Morris RE

更新日期：1996-09-27 00:00:00

abstract：BACKGROUND:Targeting 2-hr postdose cyclosporine (C2) levels to 1,000 to 1,700 mg/dL during the first 6 months after renal transplantation is recommended for triple immunosuppressive regimens. This trial determines whether lower C2 levels could be targeted safely in de novo kidney transplant recipients under a quadruple...

journal_title：Transplantation

authors： Hardinger KL,Schnitzler MA,Koch MJ,Enkvetchakul D,Desai N,Jendrisak M,Lowell JA,Miller B,Shenoy S,Brennan DC

更新日期：2004-10-27 00:00:00

abstract：:Balb/c (H-2d) mice were transfused weekly with 0.1 ml of whole blood from C3H (H-2k) mice. One week after 3 blood transfusions (BT), the mice were bled and the sera collected and pooled. The 3BT serum was absorbed twice with C3H lymphocytes and IgG isolated by ion-exchange chromatography. Balb/c anti-C3H, Balb/c anti-...

journal_title：Transplantation

authors： Singal DP,Ludwin D,Joseph S,Blajchman MA,Ofosu FA,Liao SK

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:We investigated the hypothesis that Foxp3+ cells are an integral component of antiallograft immunity but are dominated by pathogenic effectors. METHODS:Wild-type H-2b C57BL/6 (B6) mice or B6 mice with a targeted disruption of c-Rel gene (c-Rel-/-) were used as recipients of islet grafts from allogeneic DBA/...

journal_title：Transplantation

authors： Yang H,Ding R,Sharma VK,Hilaire FS,Lagman M,Li B,Thomas DA,Luo X,Song P,Stauffer C,August P,Suthanthiran M

更新日期：2007-06-27 00:00:00

abstract：:Three hundred thirty-two marrow graft recipients and 241 healthy marrow donors were studied by skin testing with recall and neoantigens. Two hundred thirty patients with leukemia and seventy-eight patients with aplastic anemia received allogeneic HLA-identical sibling marrow. Twenty-four patients with leukemia receive...

journal_title：Transplantation

authors： Witherspoon RP,Matthews D,Storb R,Atkinson K,Cheever M,Deeg HJ,Doney K,Kalbfleisch J,Noel D,Prentice R

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Lipid peroxidation by free radicals is a key step in the development of atherosclerosis. Chronic graft nephropathy (CGN) is a common cause of allograft failure and shares many histologic features with atherosclerosis. Although hyperlipidemia is a common finding in renal transplant recipients, not all patient...

journal_title：Transplantation

authors： Morris-Stiff GJ,Oleesky D,Jurewicz WA

更新日期：2003-10-15 00:00:00

abstract：:By cytolysis and monolayer absorption tests, the kinetics of the generation of CBA/H cytotoxic lymphocytes (Tc) in response to stimulation by H-2b antigens have been analyzed in vitro. The Tc population which reacts with public antigens of H-2b and H-2d strains shows peak activity in culture at 4 to 5 days, then rapi...

journal_title：Transplantation

authors： Schnagl HY,Boyle W

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Systemic amyloidosis complicated by heart failure is associated with high cardiovascular morbidity and mortality. Heart transplantation for patients with systemic amyloidosis is controversial due to recurrence of disease in the transplanted organ or progression of disease in other organs. METHODS:All patien...

journal_title：Transplantation

authors： Maurer MS,Raina A,Hesdorffer C,Bijou R,Colombo P,Deng M,Drusin R,Haythe J,Horn E,Lee SH,Marboe C,Naka Y,Schulman L,Scully B,Shapiro P,Prager K,Radhakrishnan J,Restaino S,Mancini D

更新日期：2007-03-15 00:00:00

abstract：:The development of allospecific cellular immunity during acute rat renal allograft rejection parallels alterations occurring in arachidonic acid metabolism, including increased production of the vasoconstrictor eicosanoid thromboxane A2 (TxA2). We have previously demonstrated that chronic inhibition of thromboxane syn...

journal_title：Transplantation

authors： Ruiz P,Coffman TM,Klotman PE,Sanfilippo F

更新日期：1989-10-01 00:00:00

abstract：:A worldwide shortage of cadaveric donors has led to the increased utilization of elderly living donors, with controversial results. In an attempt to assess the effect of donor age on graft survival and subsequent renal function, we analyzed our clinical results in 276 consecutive recipients of living related renal tra...

journal_title：Transplantation

authors： Sumrani N,Delaney V,Ding ZK,Davis R,Daskalakis P,Tejani A,Butt K,Hong J

更新日期：1991-02-01 00:00:00

abstract：:The Southeastern Regional Organ Procurement Program has developed a computerized system for the selection of organ transplant recipients. This system has proven to be a useful method for the rapid selection of histocompatible recipients for organ transplants from a large pool of potential recipients in a wide geograp...

journal_title：Transplantation

authors： Stulting RD,Ward FE

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) after solid organ transplantation is rare, with only six AML cases after liver transplantation (LT) being reported. METHODS:Characteristics of three AML cases observed among 799 recipients of LT in the authors' institution and estimation of the standardized incidence ratio (SIR)...

journal_title：Transplantation

authors： Camós M,Esteve J,Rimola A,Grande L,Rozman M,Colomer D,Villamor N,Costa D,Montserrat E

更新日期：2004-01-27 00:00:00

abstract：:Patients with steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis (FGS) who develop end-stage renal disease are at risk for recurrence of the disease following renal transplantation. Recurrence of the nephrotic syndrome in renal allografts of two children with primary FGS was successfully contr...

journal_title：Transplantation

authors： Laufer J,Ettenger RB,Ho WG,Cohen AH,Marik JL,Fine RN

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Recent evidence has suggested that inconsistencies in human-islet yields after collagenase digestion are attributed to the activation of endogenous enzymes of the cadaveric donor pancreas. Inhibition of protease activity by Pefabloc (0.4 mM; Roche Biochemicals Inc., Indianapolis, IN) has recently been shown ...

journal_title：Transplantation

authors： Rose NL,Palcic MM,Helms LM,Lakey JR

更新日期：2003-02-27 00:00:00

abstract：:Possible explanations for the immune deficiency usually associated with graft-versus-host disease include defective lymphocyte differentiation and active suppressor cell mechanisms. The present observations in a patient with chronic graft-versus-host disease delineate yet another possible mechanism: a failure of succe...

journal_title：Transplantation

authors： Dosch HM,Gelfand EW

更新日期：1981-01-01 00:00:00

abstract：:Cyclosporine (CsA) is an immunosuppressive drug requiring dose individualization and regular control due to its highly variable pharmacokinetics. Since gastroparesis may influence the absorption of CsA, a randomized cross-over study was performed to assess the pharmacokinetics and tolerability of a novel microemulsion...

journal_title：Transplantation

authors： van der Pijl JW,Srivastava N,Denouël J,Burggraaf J,Schoemaker RC,van der Woude FJ,Cohen AF

更新日期：1996-08-27 00:00:00