Abstract:
:Transcatheter treatment of children with congenital heart disease such as coarctation of the aorta and pulmonary artery stenosis currently involves the use of metal stents. While these provide good short term results, there are long term complications with their use. Children outgrow metal stents, obligating them to future transcatheter dilations and eventual surgical removal. A bioabsorbable stent, or a stent that goes away with time, would solve this problem. Bioabsorbable stents are being developed for use in coronary arteries, however these are too small for use in pediatric congenital heart disease. A bioabsorbable stent for use in pediatric congenital heart disease needs to be low profile, expandable to a diameter 8 mm, provide sufficient radial strength, and absorb quickly enough to allow vessel growth. Development of absorbable coronary stents has led to a great understanding of the available production techniques and materials such as bioabsorbable polymers and biocorrodable metals. Children with congenital heart disease will hopefully soon benefit from the current generation of bioabsorbable and biocorrodable materials and devices.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Alexy RD,Levi DSdoi
10.1155/2013/137985subject
Has Abstractpub_date
2013-01-01 00:00:00pages
137985eissn
2314-6133issn
2314-6141journal_volume
2013pub_type
杂志文章,评审abstract:BACKGROUND AND PURPOSE:Primary malignant spine/spinal tumors (PMSTs) are rare and life-threatening diseases. In this study, we demonstrated the advantage of volume-based 18F-FDG PET/CT metabolic parameter, metabolic tumor volume (MTV), for assessing the aggressiveness of PMSTs. MATERIALS AND METHODS:We retrospectively...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8132676
更新日期:2017-01-01 00:00:00
abstract::Candida krusei is osmotolerant yeast used for the production of glycerol. Addition of osmolyte such as NaCl into culture medium can increase the production of glycerol from glucose, but osmolytes may burden the glycerol separation. A coencapsulation method was suggested to create local extracellular hyperosmotic stres...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/467263
更新日期:2013-01-01 00:00:00
abstract::Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In general, high leve...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/981867
更新日期:2014-01-01 00:00:00
abstract::We undertook an investigation to advance understanding of the host-range dynamics and biocontrol implications of Cochliobolus lunatus in the past decade. Potato (Solanum tuberosum L) farms were routinely surveyed for brown-to-black leaf spot disease caused by C. lunatus. A biphasic gene data set was assembled and data...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/378372
更新日期:2014-01-01 00:00:00
abstract::Each year, hundreds of millions of people travel across international borders or even oceans, and up to 230 million may remain for long periods. Among these, 3-5 million settle permanently in their new homes, with about 1 million migrating permanently to the United States of America. This may result in transport of pa...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/763715
更新日期:2015-01-01 00:00:00
abstract::In previous studies, we have demonstrated the function of uc.167 in the heart development. DNA methylation plays a crucial role in regulating the expression of developmental genes during embryonic development. In this study, the methylomic landscape was investigated in order to identify the DNA methylation alterations...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4658024
更新日期:2018-05-30 00:00:00
abstract::Neem (Azadirachta indica A. Juss) oil (NO) was assayed against forty-eight isolates of Escherichia coli by standardised disc diffusion test and microdilution test. By molecular biology characterization, fourteen isolates resulted in diarrheagenic E. coli with sixteen primer pairs that specifically amplify unique seque...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/343610
更新日期:2015-01-01 00:00:00
abstract::Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly(l-lactide-co-ε-caprolactone) (PLCL) scaffolds were printed by a 3D printing technology, low-temperature deposition manufacturing (LDM), and then PLCL scaffolds wer...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/5147156
更新日期:2018-02-28 00:00:00
abstract::Bone loss and fractures may call for the use of bone substituting materials, such as calcium phosphate cements (CPCs). CPCs can be degradable, and, to determine their limitations in terms of applications, their mechanical as well as chemical properties need to be evaluated over longer periods of time, under physiologi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/575079
更新日期:2015-01-01 00:00:00
abstract::Background. Atrial natriuretic peptide (ANP) considerably influences blood pressure regulation through water and sodium homoeostasis. Several of the studies have utilized anonymous genetic polymorphic markers and made inconsequent claims about the ANP relevant disorders. Thus, we screened Insertion/Deletion (ID) and G...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/6712529
更新日期:2016-01-01 00:00:00
abstract::Tobacco smoking continues to be a leading cause of disease and mortality. Recent research has confirmed the important role of nicotinic acetylcholine receptor (nAChR) gene cluster on chromosome 15q 24-25 in nicotine dependence and smoking. In this study we tested the association of smoking initiation, age at onset of ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/350348
更新日期:2015-01-01 00:00:00
abstract::Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB). The association between HBV infection and human leukocyte antigen- (HLA-) DQ polymorphism (rs2856718 and rs7453920) has been demonstrated in other studies; however, the results were controversial or inconclusive. Therefore,...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/9679843
更新日期:2017-01-01 00:00:00
abstract::Cardiac computed tomography angiography (CCTA) is widely used as a diagnostic tool for evaluation of coronary artery disease (CAD). Despite the excellent capability to rule-out CAD, CCTA may overestimate the degree of stenosis; furthermore, CCTA analysis can be time consuming, often requiring advanced postprocessing t...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/6649410
更新日期:2020-12-16 00:00:00
abstract::Chosen aspects of examinations of inorganic gunshot particles by means of scanning electron microscopy and energy dispersive X-ray spectrometry technique are presented. The research methodology of particles was worked out, which included a precise and repeatable procedure of the automatic detection and identification ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/428038
更新日期:2014-01-01 00:00:00
abstract::This study investigates the mechanism underlying the improving effect of zinc on fertility in obese rats using proteomics. The effects of three different doses of ZnSO4 on spermatogenesis and hormone levels were studied. Testicular spermatogenesis was observed by HE staining. Serum estrogen and testosterone levels wer...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9876363
更新日期:2020-05-04 00:00:00
abstract::The aim of the study was to assess the granulocyte colony-stimulating factor (G-CSF) effects on unresponsive thin (<7 mm) endometrium in women undergoing in vitro fertilization (IVF). We included thirty-seven subjects who had thin unresponsive endometrium on the day of triggering ovulation. These patients also failed ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/913235
更新日期:2014-01-01 00:00:00
abstract::Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9436280
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Osteomyelitis is a severe orthopaedic complication which is difficult to diagnose and treat. Previous experimental studies mainly focussed on evaluating osteomyelitis in the presence of an implant or used a sclerosing agent to promote infection onset. In contrast, we focused on the longitudinal assessment ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/424652
更新日期:2014-01-01 00:00:00
abstract::Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage display peptide li...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9483928
更新日期:2018-06-05 00:00:00
abstract::The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/961314
更新日期:2015-01-01 00:00:00
abstract::We aimed to explore the effects of raloxifene (RAL) on the proliferation and apoptosis of human aortic valve interstitial cells (AVICs). Different concentrations of RAL were used to act on AVICs. MTS kit is used to test the effects of different concentrations of RAL on the proliferation of AVICs. Cell cycle and apopto...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5473204
更新日期:2016-01-01 00:00:00
abstract::The occurrence of head and neck cancer (HNC) is associated with smoking and alcohol drinking. Tobacco smoking exposes smokers to a series of carcinogenic chemicals. Cytochrome P450 enzymes (CYP450s), such as CYP1A1, CYP1B1, and CYP2D6, usually metabolize carcinogens to their inactive derivatives, but they occasionally...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/582768
更新日期:2013-01-01 00:00:00
abstract::Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmis...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/350195
更新日期:2014-01-01 00:00:00
abstract::Traumatic brain injury (TBI) leads to important and deleterious neuroinflammation, as evidenced by indicators such as edema, cytokine production, induction of nitric oxide synthase, and leukocyte infiltration. After TBI, cerebral vascular endothelial cells play a crucial role in the pathogenesis of inflammation. In ou...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/910260
更新日期:2014-01-01 00:00:00
abstract::Postoperative surgical site infections (SSIs) are more common complications after spinal surgery. SSIs often require extended hospitalisation and may worsen overall clinical outcomes. A retrospective database review of consecutive patients with traditional open lumbar spinal surgery was performed. SSIs patients were i...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/842010
更新日期:2015-01-01 00:00:00
abstract::Studies of aseptic loosening showed an influence of calcitonin and α-CGRP, both encoded from the calcitonin/α-CGRP (CALCA) gene by alternative splicing. The aim of this study was to detect a possible association of the CALCA polymorphisms P1(rs1553005), P2(rs35815751), P3(rs5240), and P4(rs2956) with the time to asept...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3687415
更新日期:2018-06-05 00:00:00
abstract:Introduction:The sources of Reactive Oxidative Species (ROS) in the organism are the respiratory processes occurring in cells catalyzed by different enzymes. Operation of ROS is balanced by antioxidants, the compounds; although present in low concentrations, they significantly inhibit the degree of oxidation of particu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6038106
更新日期:2018-01-02 00:00:00
abstract:Background:As a newly discovered lncRNA, bladder cancer-associated transcript 1 (BLACAT1) has been reported to correlate with poor clinical outcomes in several different cancers. This study aimed to evaluate its generalized predictive value for cancer prognosis. Materials and Methods:We thoroughly searched PubMed, Emb...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/1275491
更新日期:2019-04-02 00:00:00
abstract::Recent research had shown a correlation between aging and decreasing Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. However, how GABA level varies with age in the medial portion of the brain has not yet been studied. The purpose of this study was to investigate the GABA level var...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/6523909
更新日期:2016-01-01 00:00:00
abstract::Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5202750
更新日期:2019-10-02 00:00:00