Diagnosis and Treatment of Vulvar Lichen Sclerosus: An Update for Dermatologists.

abstract：:The objective of this article is to provide a brief, but critical, overview of the evidence related to complementary/alternative medicine (CAM) use, and to offer valid and useful information for dermatologists in clinical practice. Systematic literature searches were conducted on these databases: Medline, EMBASE, The ...

journal_title：American journal of clinical dermatology

authors： Ernst E,Pittler MH,Stevinson C

更新日期：2002-01-01 00:00:00

abstract：:Granular parakeratosis (GP) is a rare, idiopathic, and benign skin condition that presents classically as erythematous to brown hyperkeratotic papules that can coalesce into plaques. Axillary GP was initially observed by Northcutt and colleagues and has since been described in various other areas of the body including...

journal_title：American journal of clinical dermatology

authors： Ding CY,Liu H,Khachemoune A

更新日期：2015-12-01 00:00:00

abstract：:Most people in modern society are exposed daily to fragrance ingredients from one or more sources. Fragrance ingredients are also one of the most frequent causes of contact allergic reactions. The diagnosis is made by patch testing with a mixture of fragrance ingredients, the fragrance mix. This gives a positive patch...

journal_title：American journal of clinical dermatology

authors： Johansen JD

更新日期：2003-01-01 00:00:00

abstract：:The family of toll-like receptors (TLRs) plays a central role in the cutaneous immune defense system. To date, different TLRs have been found on several major cell populations of the skin, such as keratinocytes, fibroblasts, antigen-presenting cells, and melanocytes. Activation of TLRs leads, via different intracellul...

journal_title：American journal of clinical dermatology

authors： Terhorst D,Kalali BN,Ollert M,Ring J,Mempel M

更新日期：2010-01-01 00:00:00

abstract：:Diagnosing acne is easy. However, treatment must be adapted to the type and severity of acne, and must also take into account the impact of acne on patients' quality of life. As there is not always a correlation between the severity of acne and its impact on quality of life, it can be helpful for the dermatologist to ...

journal_title：American journal of clinical dermatology

authors： Dréno B

更新日期：2006-01-01 00:00:00

abstract：:Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid hormones, and porphyrins. The topical use ...

journal_title：American journal of clinical dermatology

authors： Ebner F,Heller A,Rippke F,Tausch I

更新日期：2002-01-01 00:00:00

abstract：:Seborrheic dermatitis (SD) is characterized by erythematous pruritic patches and plaques with greasy scale that occur in sebaceous areas. It is common, affecting up to 3% of the population. Past treatments have relied on a wide variety of anti-inflammatory and antifungal agents, but corticosteroids have limited use be...

journal_title：American journal of clinical dermatology

authors： Cook BA,Warshaw EM

更新日期：2009-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF)-α inhibitors are an alternative to oral systemic therapies for psoriasis. Data regarding the safety of TNF-α inhibitors from randomized clinical trials may not fully reflect the effects on the clinic patient population receiving the therapy, but other sources of information are available. W...

journal_title：American journal of clinical dermatology

authors： Semble AL,Davis SA,Feldman SR

更新日期：2014-02-01 00:00:00

abstract：:After a marked decline in the number of syphilis cases in the context of AIDS prevention campaigns, a significant increase has been observed in states of the former Soviet Union since 1994. In recent years, outbreaks have also been reported in the US, Canada, and several European countries. The current epidemic in the...

journal_title：American journal of clinical dermatology

authors： Lautenschlager S

更新日期：2006-01-01 00:00:00

abstract：:Eruptive melanocytic nevi (EMN) is a phenomenon characterized by the sudden onset of nevi. Our objective was to compile all published reports of EMN to identify possible precipitating factors and to evaluate the clinical appearance and course. We conducted a systematic bibliographic search and selected 93 articles, re...

journal_title：American journal of clinical dermatology

authors： Burian EA,Jemec GBE

更新日期：2019-10-01 00:00:00

abstract：:Subcutaneous adalimumab (Humira®) is a tumour necrosis factor-α blocker that is the only approved agent for the treatment of moderate to severe hidradenitis suppurativa (HS) in several countries worldwide. This article reviews the clinical efficacy and safety of subcutaneous adalimumab in patients with moderate to sev...

journal_title：American journal of clinical dermatology

authors： Kim ES,Garnock-Jones KP,Keam SJ

更新日期：2016-10-01 00:00:00

abstract：:Tildrakizumab (tildrakizumab-asmn in the USA) [Ilumetri®; Ilumya™] is a humanized monoclonal antibody (mAb) that selectively targets the p19 subunit of interleukin (IL)-23, thereby inhibiting the IL-23/IL-17 axis, the signalling pathway primarily implicated in the immunopathogenesis of psoriasis. Administered subcutan...

journal_title：American journal of clinical dermatology

authors： Frampton JE

更新日期：2019-04-01 00:00:00

abstract：:Ocular diseases associated with atopic dermatitis (AD) may be sight-threatening. A general understanding of the pathophysiology, diagnosis, and treatment of atopic eye disease may assist dermatologists in knowing when to refer to ophthalmology and in co-managing these diseases with ophthalmologists. Ocular diseases as...

journal_title：American journal of clinical dermatology

authors： Beck KM,Seitzman GD,Yang EJ,Sanchez IM,Liao W

更新日期：2019-12-01 00:00:00

abstract：:Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Mult...

journal_title：American journal of clinical dermatology

authors： Kechichian E,Ezzedine K

更新日期：2018-04-01 00:00:00

abstract：:Systemic sclerosis is an extremely variable disease in its manifestations and consequently, treatment needs to be individualized depending on the specific problems that each patient has. Limited scleroderma patients have a prolonged duration of Raynaud's phenomenon and puffy fingers before they develop any skin thicke...

journal_title：American journal of clinical dermatology

authors： Steen VD

更新日期：2001-01-01 00:00:00

abstract：:The etiologies of a variety of skin conditions associated with diabetes have not been fully explained. One possible etiological factor is diabetic microangiopathy, which is known to affect the eyes and kidneys in patients with diabetes. There are many mechanisms by which diabetes may cause microangiopathy. These inclu...

journal_title：American journal of clinical dermatology

authors： Ngo BT,Hayes KD,DiMiao DJ,Srinivasan SK,Huerter CJ,Rendell MS

更新日期：2005-01-01 00:00:00

abstract：:The treatment of cutaneous T cell lymphoma (CTCL), which includes mycosis fungoides and Sezary syndrome, has been in a state of continual change over recent decades, as new therapies are constantly emerging in the search for more effective treatments for the disease. However, prognosis and survival of patients with CT...

journal_title：American journal of clinical dermatology

authors： Apisarnthanarax N,Talpur R,Duvic M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...

journal_title：American journal of clinical dermatology

authors： Lin CC,Lin HC,Chiu HW

更新日期：2019-06-01 00:00:00

abstract：:Black hairy tongue (BHT) is a benign condition commonly found among people who smoke, have poor oral hygiene, are immunocompromised, or have a medical condition limiting their ability to practice good oral hygiene. Though this condition is harmless, patients need to be educated on etiology as many common medications a...

journal_title：American journal of clinical dermatology

authors： Schlager E,St Claire C,Ashack K,Khachemoune A

更新日期：2017-08-01 00:00:00

abstract：:Topical retapamulin (Altabax, Altargo) is the first pleuromutilin antibacterial approved for the treatment of uncomplicated superficial skin infections caused by Staphylococcus aureus (excluding methicillin-resistant S. aureus [MRSA]) and Streptococcus pyogenes in patients aged > or = 9 months. In the EU, retapamulin ...

journal_title：American journal of clinical dermatology

authors： Yang LP,Keam SJ

更新日期：2008-01-01 00:00:00

abstract：:Trigeminal trophic syndrome (TTS) is the historic name for neuropathic self-induced facial ulceration from abnormal sensory symptoms leading to uncontrolled scratching. Anatomic co-localization of sensory loss (numbness) plus neuropathic itch and pain permits painless scratching. If the itch is severe, some patients w...

journal_title：American journal of clinical dermatology

authors： Curtis AR,Oaklander AL,Johnson A,Yosipovitch G

更新日期：2012-04-01 00:00:00

abstract：:Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...

journal_title：American journal of clinical dermatology

authors： Layton AM

更新日期：2001-01-01 00:00:00

abstract：:Lichen planus is a relatively common disorder of the stratified squamous epithelia. Most dental and medical practitioners see patients with lichen planus, but not all are recognized as having the disease. Patients with lichen planus may have concomitant involvement of the disease in multiple sites. Oral lichen planus ...

journal_title：American journal of clinical dermatology

authors： Scully C,Eisen D,Carrozzo M

更新日期：2000-09-01 00:00:00

abstract：:Solar, and particularly UV, radiation causes molecular and cellular damage with resultant histopathologic and clinical degenerative changes, leading in turn to photosensitivity, photo-aging, and skin cancer. While our bodies have some natural UV defenses, additional protection from the sun is essential, including sun ...

journal_title：American journal of clinical dermatology

authors： Gonzaga ER

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Topical coal tar is a well known and effective treatment for psoriasis, but the messiness, staining, odor, and inconvenience associated with its use make patient satisfaction and compliance a challenge. OBJECTIVE:To determine the efficacy, patient tolerability, and cosmetic acceptability of a new topical li...

journal_title：American journal of clinical dermatology

authors： Alora-Palli MB,Perkins AC,Van Cott A,Kimball AB

更新日期：2010-01-01 00:00:00

abstract：:Narrow-band ultraviolet B (NBUVB) phototherapy is an important treatment modality in dermatology. The most common dermatological indications for NBUVB include psoriasis, atopic dermatitis and vitiligo; however, it has been found to be an effective and well-tolerated treatment option in various other dermatoses. The ef...

journal_title：American journal of clinical dermatology

authors： Sokolova A,Lee A,D Smith S

更新日期：2015-12-01 00:00:00

abstract：:Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has ...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Carviel J,Abramovits W

更新日期：2017-02-01 00:00:00

abstract：:There is a high unmet clinical need for new and better treatments in acne vulgaris. Propionibacterium acnes has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity, keratinocytes and sebaceous glands of the pilosebaceous follicle. The role of P. acnes in acne confers legit...

journal_title：American journal of clinical dermatology

authors： Simonart T

更新日期：2013-12-01 00:00:00

abstract：:Immunotherapy has revolutionized the treatment of melanoma. Targeting of the immune checkpoints cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 has led to improved survival in a subset of patients. Unfortunately, the use of immune checkpoint inhibitors is associated with significant sid...

journal_title：American journal of clinical dermatology

authors： Rizk EM,Seffens AM,Trager MH,Moore MR,Geskin LJ,Gartrell-Corrado RD,Wong W,Saenger YM

更新日期：2020-02-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2002-01-01 00:00:00