Granular Parakeratosis: A Comprehensive Review and a Critical Reappraisal.

Abstract:

:Granular parakeratosis (GP) is a rare, idiopathic, and benign skin condition that presents classically as erythematous to brown hyperkeratotic papules that can coalesce into plaques. Axillary GP was initially observed by Northcutt and colleagues and has since been described in various other areas of the body including other intertriginous and non-intertriginous sites. The term "granular parakeratosis" is now used to describe not only the skin condition, but also a distinctive histological reactive pattern on biopsy specimens that are either regarded as the disease itself, or merely as an incidental finding. Upon review of the current findings, opinions, and associations of this entity, we propose the reappraisal of GP as a reactive pattern, rather than a distinct entity.

journal_name

Am J Clin Dermatol

authors

Ding CY,Liu H,Khachemoune A

doi

10.1007/s40257-015-0148-2

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

495-500

issue

6

eissn

1175-0561

issn

1179-1888

pii

10.1007/s40257-015-0148-2

journal_volume

16

pub_type

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