Role of UV light in photodamage, skin aging, and skin cancer: importance of photoprotection.

abstract：:Long-term corticosteroid treatment is the most common secondary cause of bone loss. Patients treated with long-term corticosteroid therapy may develop osteopenia or osteoporosis, and many have fractures. It is difficult to predict which corticosteroid-treated patients will develop significant skeletal complications be...

journal_title：American journal of clinical dermatology

authors： Clarke BL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Topical coal tar is a well known and effective treatment for psoriasis, but the messiness, staining, odor, and inconvenience associated with its use make patient satisfaction and compliance a challenge. OBJECTIVE:To determine the efficacy, patient tolerability, and cosmetic acceptability of a new topical li...

journal_title：American journal of clinical dermatology

authors： Alora-Palli MB,Perkins AC,Van Cott A,Kimball AB

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is an allergic disorder caused by both immunological dysregulation and epidermal barrier defect. Several studies have investigated the association between AD and mental health disorders. Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental conditions characte...

journal_title：American journal of clinical dermatology

authors： Billeci L,Tonacci A,Tartarisco G,Ruta L,Pioggia G,Gangemi S

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Efforts have been recently made to investigate simple, objective, accurate, and reproducible methods of clinical/noninvasive assessment of nonsegmental vitiligo. However, studies have mostly considered quantitative or semiquantitative parameters, almost neglecting the purely qualitative appearance of vitilig...

journal_title：American journal of clinical dermatology

authors： Menchini G,Comacchi C,Cappugi P,Torchia D

更新日期：2013-02-01 00:00:00

abstract：:Immunotherapy has revolutionized the treatment of melanoma. Targeting of the immune checkpoints cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 has led to improved survival in a subset of patients. Unfortunately, the use of immune checkpoint inhibitors is associated with significant sid...

journal_title：American journal of clinical dermatology

authors： Rizk EM,Seffens AM,Trager MH,Moore MR,Geskin LJ,Gartrell-Corrado RD,Wong W,Saenger YM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Scalp psoriasis is commonly the initial presentation of psoriasis, and almost 80 % of patients with psoriasis will eventually experience it. OBJECTIVE:Although several systematic reviews and guidelines exist, an up-to-date evidence-based review including more recent progress on the use of biologics and new ...

journal_title：American journal of clinical dermatology

authors： Wang TS,Tsai TF

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...

journal_title：American journal of clinical dermatology

authors： Lin CC,Lin HC,Chiu HW

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Cutaneous lichen planus (CLP) is an inflammatory dermatosis. Its chronic relapsing course and frequently spontaneous regression hamper the assessment of treatment effectiveness. OBJECTIVE:To evaluate the efficacy of available treatment modalities for CLP. DATA SOURCES:PubMed, Cochrane Central Register of C...

journal_title：American journal of clinical dermatology

authors： Atzmony L,Reiter O,Hodak E,Gdalevich M,Mimouni D

更新日期：2016-02-01 00:00:00

abstract：:Epidermolysis bullosa (EB) represents a group of inherited blistering skin diseases, some forms of which are associated with considerable morbidity and increased mortality. Notably, in recessive dystrophic EB there can be extensive muco-cutaneous fragility and disease complications such as scars, contractures, anemia,...

journal_title：American journal of clinical dermatology

authors： Hsu CK,Wang SP,Lee JY,McGrath JA

更新日期：2014-02-01 00:00:00

abstract：:Systemic sclerosis is an extremely variable disease in its manifestations and consequently, treatment needs to be individualized depending on the specific problems that each patient has. Limited scleroderma patients have a prolonged duration of Raynaud's phenomenon and puffy fingers before they develop any skin thicke...

journal_title：American journal of clinical dermatology

authors： Steen VD

更新日期：2001-01-01 00:00:00

abstract：:Spinosad 0.9% suspension is a topical treatment for head-lice infestation (pediculosis capitis) that has been approved in the US as a prescription medicine. Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine ...

journal_title：American journal of clinical dermatology

authors： McCormack PL

更新日期：2011-10-01 00:00:00

abstract：:Seborrheic dermatitis (SD) is characterized by erythematous pruritic patches and plaques with greasy scale that occur in sebaceous areas. It is common, affecting up to 3% of the population. Past treatments have relied on a wide variety of anti-inflammatory and antifungal agents, but corticosteroids have limited use be...

journal_title：American journal of clinical dermatology

authors： Cook BA,Warshaw EM

更新日期：2009-01-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2003-01-01 00:00:00

abstract：:Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...

journal_title：American journal of clinical dermatology

authors： Layton AM

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED:Topical application of the antibacterial agent metronidazole is effective in the treatment of moderate to severe rosacea, although its mechanism of action has yet to be clearly established. Metronidazole preparations (0.75 and 1% cream, 0.75% gel and 0.75% lotion) were significantly more effective than place...

journal_title：American journal of clinical dermatology

authors： McClellan KJ,Noble S

更新日期：2000-05-01 00:00:00

abstract：:Halobetasol propionate (HP) 0.5% ointment and cream are class I topical corticosteroids. We review the efficacy and tolerability of HP for treatment of plaque psoriasis in the English language literature. The efficacy of HP ointment and cream is consistently superior to other super-potent topical corticosteroids. Loca...

journal_title：American journal of clinical dermatology

authors： Rivera AM,Hsu S

更新日期：2005-01-01 00:00:00

abstract：:Genital herpes, an incurable viral disease that can have a devastating impact on affected patients, is a serious public health concern affecting one in four Americans. Episodic treatment with nucleoside analogs for 3-5 days is the most common method of treatment; however, since maximum viral replication occurs within ...

journal_title：American journal of clinical dermatology

authors： Tyring S,Berger T,Yen-Moore A,Tharp M,Hamed K

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Evidence regarding what comprises effective education for acne vulgaris patients is lacking. Internet-based education may improve patient knowledge of this condition. OBJECTIVES:Our objective was to compare the effectiveness of standard web-based education and an automated counseling website in improving ac...

journal_title：American journal of clinical dermatology

authors： Tuong W,Wang AS,Armstrong AW

更新日期：2015-02-01 00:00:00

abstract：:The etiologies of a variety of skin conditions associated with diabetes have not been fully explained. One possible etiological factor is diabetic microangiopathy, which is known to affect the eyes and kidneys in patients with diabetes. There are many mechanisms by which diabetes may cause microangiopathy. These inclu...

journal_title：American journal of clinical dermatology

authors： Ngo BT,Hayes KD,DiMiao DJ,Srinivasan SK,Huerter CJ,Rendell MS

更新日期：2005-01-01 00:00:00

abstract：:Viral skin infections are common findings in organ transplant recipients. The most important etiological agents are the group of human herpesviruses (HHV), human papillomaviruses (HPV), and molluscum contagiosum virus. HHV that are important in this group of patients are herpes simplex virus (HSV) types 1 and 2, varic...

journal_title：American journal of clinical dermatology

authors： Tan HH,Goh CL

更新日期：2006-01-01 00:00:00

abstract：:Cutaneous reactions to tattoos are not uncommon and various histologic patterns have been reported, including lichenoid, granulomatous, eczematous, and pseudolymphomatous reactions. Such patterns may develop with highly variable delay after the tattooing procedure. We report three strikingly similar cases of a fast-oc...

journal_title：American journal of clinical dermatology

authors： Kluger N,Durand L,Minier-Thoumin C,Plantier F,Cotten H,Berteloot E,Blatière V,Dereure O

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is not well characterized. PURPOSE:The objective of this st...

journal_title：American journal of clinical dermatology

authors： Al-Dabagh A,Davis SA,Kinney MA,Huang K,Feldman SR

更新日期：2013-06-01 00:00:00

abstract：:Airbags are restraining safety devices, but their activation may sometimes induce injuries during road accidents. Rapid deceleration due to an impact causes the ignition of a sodium azide cartridge, which releases nitrogen gas to inflate the nylon rubber bag. Numerous high-temperature gases, sodium hydroxide, carbon d...

journal_title：American journal of clinical dermatology

authors： Corazza M,Trincone S,Virgili A

更新日期：2004-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF)-α inhibitors are an alternative to oral systemic therapies for psoriasis. Data regarding the safety of TNF-α inhibitors from randomized clinical trials may not fully reflect the effects on the clinic patient population receiving the therapy, but other sources of information are available. W...

journal_title：American journal of clinical dermatology

authors： Semble AL,Davis SA,Feldman SR

更新日期：2014-02-01 00:00:00

abstract：:Microdermabrasion is a simple, safe, office cosmetic procedure in which aluminum oxide crystals or other abrasive substances are blown onto the face, then vacuumed off, using a single handpiece. This procedure has rapidly become widely utilized for a variety of cosmetic objectives, including the improvement of photoag...

journal_title：American journal of clinical dermatology

authors： Spencer JM

更新日期：2005-01-01 00:00:00

abstract：:Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Mult...

journal_title：American journal of clinical dermatology

authors： Kechichian E,Ezzedine K

更新日期：2018-04-01 00:00:00

abstract：:Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has ...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Carviel J,Abramovits W

更新日期：2017-02-01 00:00:00

abstract：:The family of toll-like receptors (TLRs) plays a central role in the cutaneous immune defense system. To date, different TLRs have been found on several major cell populations of the skin, such as keratinocytes, fibroblasts, antigen-presenting cells, and melanocytes. Activation of TLRs leads, via different intracellul...

journal_title：American journal of clinical dermatology

authors： Terhorst D,Kalali BN,Ollert M,Ring J,Mempel M

更新日期：2010-01-01 00:00:00

abstract：:Photochemotherapy with methoxsalen (8-methoxypsoralen) and long wavelength ultraviolet (UV) radiation (referred to as 'PUVA' for psoralen plus UVA) is commonly used to treat psoriasis and vitiligo. These vastly different diseases respond to the therapy by different mechanisms even though the immediate effects of the t...

journal_title：American journal of clinical dermatology

authors： Gasparro FP

更新日期：2000-11-01 00:00:00

abstract：:Granuloma annulare (GA) is a chronic inflammatory disease of unknown etiology characterized by the development of plaques preferentially localized to the distal extremities. Spontaneous remission and relapses are quite common and the course of GA is not easy to predict. Moreover, most therapeutic regimens have been us...

journal_title：American journal of clinical dermatology

authors： Murdaca G,Colombo BM,Barabino G,Caiti M,Cagnati P,Puppo F

更新日期：2010-12-01 00:00:00