Abstract:
:Narrow-band ultraviolet B (NBUVB) phototherapy is an important treatment modality in dermatology. The most common dermatological indications for NBUVB include psoriasis, atopic dermatitis and vitiligo; however, it has been found to be an effective and well-tolerated treatment option in various other dermatoses. The efficacy of NBUVB phototherapy compares favorably with other available photo(chemo)therapy options and its efficacy is further augmented by a number of topical and systemic adjuncts. The long-term safety of NBUVB phototherapy remains to be fully elucidated; however, available data now suggest that it is safe and well-tolerated. The objective of this review was to summarize the current understanding of the safety and efficacy of NBUVB phototherapy in dermatology.
journal_name
Am J Clin Dermatoljournal_title
American journal of clinical dermatologyauthors
Sokolova A,Lee A,D Smith Sdoi
10.1007/s40257-015-0151-7subject
Has Abstractpub_date
2015-12-01 00:00:00pages
501-31issue
6eissn
1175-0561issn
1179-1888pii
10.1007/s40257-015-0151-7journal_volume
16pub_type
杂志文章,评审abstract::Diagnosing acne is easy. However, treatment must be adapted to the type and severity of acne, and must also take into account the impact of acne on patients' quality of life. As there is not always a correlation between the severity of acne and its impact on quality of life, it can be helpful for the dermatologist to ...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200607020-00003
更新日期:2006-01-01 00:00:00
abstract::Aggressive digital papillary adenocarcinoma (ADPAC) is a rare cutaneous malignant tumor. We report on a 42-year-old man presenting with a nontender firm nodule on his right thumb that had been present for 3 years. The lesion clinically resembled an acquired digital fibrokeratoma, but was found to be an ADPAC after pat...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章
doi:10.2165/00128071-200708040-00007
更新日期:2007-01-01 00:00:00
abstract::We provide a guide for dermatologists to follow if they encounter patients with a rash and clinical history suspicious of Zika virus infection, including diagnostic testing and management options. We also provide an illustrative case report of a patient from Brazil who was diagnosed with Zika virus infection after pre...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-016-0243-z
更新日期:2017-04-01 00:00:00
abstract::Uncommon types of cutaneous cancers are mainly cited in the literature as case reports and their etiology, pathogenesis and prognosis have to be surmised because of their rarity. Within this group exist the rare and also the unusual, for instance a relatively common carcinoma arising in a strange circumstance. Initial...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200203020-00002
更新日期:2002-01-01 00:00:00
abstract::Melanoma is a malignancy of pigment-producing cells that is driven by a variety of genetic mutations and aberrations. In most cases, this leads to upregulation of the mitogen-activated protein kinase (MAPK) pathway through activating mutations of upstream mediators of the pathway including BRAF and NRAS. With the adve...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-015-0159-z
更新日期:2016-02-01 00:00:00
abstract::The incidence of basal cell carcinoma is rapidly increasing and a number of treatment modalities are available. Treatment of basal cell carcinoma includes both surgical and nonsurgical approaches, some of which are traditional, and others experimental. The treatment modality utilized is dependent on both the tumor typ...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200203040-00003
更新日期:2002-01-01 00:00:00
abstract::Immunotherapy has revolutionized the treatment of melanoma. Targeting of the immune checkpoints cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 has led to improved survival in a subset of patients. Unfortunately, the use of immune checkpoint inhibitors is associated with significant sid...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-019-00475-1
更新日期:2020-02-01 00:00:00
abstract::Granular parakeratosis (GP) is a rare, idiopathic, and benign skin condition that presents classically as erythematous to brown hyperkeratotic papules that can coalesce into plaques. Axillary GP was initially observed by Northcutt and colleagues and has since been described in various other areas of the body including...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-015-0148-2
更新日期:2015-12-01 00:00:00
abstract::Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant genodermatosis with malignant potential characterized by cutaneous and extracutaneous stigmata. Aberrations in the folliculin (FLCN) gene, which is located on chromosome 17, have been discovered in individuals with this condition. Over 150 unique mutations have be...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-017-0307-8
更新日期:2018-02-01 00:00:00
abstract::Superficial fungal infections are chronic and recurring conditions. Tinea capitis is a scalp infection, primarily affecting prepubescent children. Ringworm infections, such as tinea corporis and tinea cruris, involve the glabrous skin. Tinea nigra is a rare mycotic infection that may be related to travel abroad. Piedr...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200405040-00003
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is not well characterized. PURPOSE:The objective of this st...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-013-0017-9
更新日期:2013-06-01 00:00:00
abstract::Solar, and particularly UV, radiation causes molecular and cellular damage with resultant histopathologic and clinical degenerative changes, leading in turn to photosensitivity, photo-aging, and skin cancer. While our bodies have some natural UV defenses, additional protection from the sun is essential, including sun ...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/0128071-200910001-00004
更新日期:2009-01-01 00:00:00
abstract::Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200203070-00009
更新日期:2002-01-01 00:00:00
abstract::Occupational contact dermatitis (OCD) represents 90 to 95% of all occupational dermatoses. The incidence rate of OCD is estimated to be around 0.5 to 1.9 cases per full-time worker per year. However, epidemiologic data are lacking and incidence is probably underestimated, especially in the US. Over the past 20 years, ...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200102060-00002
更新日期:2001-01-01 00:00:00
abstract::The dermis normally directs all phases of skin wound healing following tissue trauma or disease. However, in chronic wounds, the dermal matrix is insufficient to stimulate healing and assistance by external factors is needed for wound closure. Although the concept of the extracellular matrix directing wound healing is...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200708020-00001
更新日期:2007-01-01 00:00:00
abstract::Tumor necrosis factor (TNF)-α inhibitors are an alternative to oral systemic therapies for psoriasis. Data regarding the safety of TNF-α inhibitors from randomized clinical trials may not fully reflect the effects on the clinic patient population receiving the therapy, but other sources of information are available. W...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-013-0053-5
更新日期:2014-02-01 00:00:00
abstract::Hyperhidrosis is a common and distressing condition involving increased production of sweat. A variety of treatment modalities are used to try to control or reduce sweating. Sweat is secreted by eccrine glands innervated by cholinergic fibers from the sympathetic nervous system. Primary hyperhidrosis most commonly aff...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200304100-00003
更新日期:2003-01-01 00:00:00
abstract::The etiologies of a variety of skin conditions associated with diabetes have not been fully explained. One possible etiological factor is diabetic microangiopathy, which is known to affect the eyes and kidneys in patients with diabetes. There are many mechanisms by which diabetes may cause microangiopathy. These inclu...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200506040-00003
更新日期:2005-01-01 00:00:00
abstract::Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200102030-00002
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章
doi:10.1007/s40257-018-00420-8
更新日期:2019-06-01 00:00:00
abstract::Of all the psychotropic medications currently available, the mood-stabilizing agents have the highest incidence of severe and life-threatening adverse cutaneous drug reactions (ACDRs). An exanthematous eruption in a patient treated with a mood-stabilizing agent should be viewed as possibly being the initial symptom of...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200304010-00003
更新日期:2003-01-01 00:00:00
abstract::Tildrakizumab (tildrakizumab-asmn in the USA) [Ilumetri®; Ilumya™] is a humanized monoclonal antibody (mAb) that selectively targets the p19 subunit of interleukin (IL)-23, thereby inhibiting the IL-23/IL-17 axis, the signalling pathway primarily implicated in the immunopathogenesis of psoriasis. Administered subcutan...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-019-00435-9
更新日期:2019-04-01 00:00:00
abstract::Superficial mycoses are becoming increasingly resistant to current antifungal medications. As alternative therapeutic options are limited, the increasing frequency of reports of antifungal resistance is alarming. This epidemic parallels the rise of antibiotic resistance; however, the significance of this problem has y...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章
doi:10.1007/s40257-020-00580-6
更新日期:2020-12-22 00:00:00
abstract::Epidermolysis bullosa (EB) represents a group of inherited blistering skin diseases, some forms of which are associated with considerable morbidity and increased mortality. Notably, in recessive dystrophic EB there can be extensive muco-cutaneous fragility and disease complications such as scars, contractures, anemia,...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-013-0059-z
更新日期:2014-02-01 00:00:00
abstract::Chronic itch is a common skin manifestation in many connective tissue diseases. However, the cause of chronic itch in these diseases is still not fully understood. The complex, and in some cases incomplete understanding of, pathogenesis in each condition makes it difficult to target specific mediators of chronic itch....
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-016-0201-9
更新日期:2016-10-01 00:00:00
abstract::Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting co...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/11536930-000000000-00000
更新日期:2011-04-01 00:00:00
abstract::Ultrapotent topical corticosteroids are the mainstay of psoriasis treatment, used either alone or in combination with a topical vitamin D analog. Traditionally used in an ointment vehicle for psoriasis, clobetasol propionate 0.05% is also available in spray, foam, lotion, and shampoo formulations, which may provide fo...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/11311020-000000000-00000
更新日期:2009-01-01 00:00:00
abstract::Coccidioidomycosis is an endemic mycosis of the southern United States, Northern Mexico, and South America. Primary cutaneous coccidioidomycosis, despite being a very rare clinical presentation, has shown an increasing incidence. An extensive literature search for cutaneous coccidioidomycosis cases was performed using...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.1007/s40257-020-00525-z
更新日期:2020-10-01 00:00:00
abstract::Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章,评审
doi:10.2165/00128071-200304070-00007
更新日期:2003-01-01 00:00:00
abstract:SIGNIFICANCE:Psoriasis, a common immune-mediated disease, affects approximately 2% of the population worldwide. Sudden sensorineural hearing loss (SSNHL) might be a manifestation of systemic vascular involvement in autoimmune disease. However, to the best of our knowledge, there is no systematic English-language examin...
journal_title:American journal of clinical dermatology
pub_type: 杂志文章
doi:10.1007/s40257-015-0117-9
更新日期:2015-06-01 00:00:00