Chronic Pruritus and Connective Tissue Disorders: Review, Gaps, and Future Directions.

abstract：:Radiation-recall dermatitis is the occurrence, with subsequent administration of cytotoxic chemotherapy, of an acute inflammatory toxicity in a previously quiescent radiation field. It may occur from days to weeks, and sometimes years, after the radiation therapy. The precise mechanism is unknown. One hypothesis sugge...

journal_title：American journal of clinical dermatology

authors： Yeo W,Johnson PJ

更新日期：2000-03-01 00:00:00

abstract：:Itch, also known as pruritus, is the major symptom in skin diseases with a variety of etiologies and pathophysiologies. Significant progress has been achieved in understanding the pathophysiology of itch in the last 5 years. Neurophysiological experiments in humans and animals have revealed that itch is carried by spe...

journal_title：American journal of clinical dermatology

authors： Yosipovitch G,Fleischer A

更新日期：2003-01-01 00:00:00

abstract：:Pemphigus vulgaris (PV) is a severe chronic autoimmune blistering disease that affects the skin and mucous membranes. It is characterized by suprabasal acantholysis due to disruption of desmosomal connections between keratinocytes. Autoantibodies against desmosomal cadherins, desmoglein 3 and 1, have been shown to ind...

journal_title：American journal of clinical dermatology

authors： Altman EM

更新日期：2020-12-01 00:00:00

abstract：:Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has ...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Carviel J,Abramovits W

更新日期：2017-02-01 00:00:00

abstract：:Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant genodermatosis with malignant potential characterized by cutaneous and extracutaneous stigmata. Aberrations in the folliculin (FLCN) gene, which is located on chromosome 17, have been discovered in individuals with this condition. Over 150 unique mutations have be...

journal_title：American journal of clinical dermatology

authors： Tong Y,Schneider JA,Coda AB,Hata TR,Cohen PR

更新日期：2018-02-01 00:00:00

abstract：:A rapidly increasing number of people visit dermatologists for the prevention and treatment of aging skin. Sun avoidance and sunscreen use are widely accepted strategies of primary prevention against photoaging. Convincing evidence shows that topical application of retinoids has an effect on reversing, at least partia...

journal_title：American journal of clinical dermatology

authors： Antoniou C,Kosmadaki MG,Stratigos AJ,Katsambas AD

更新日期：2010-01-01 00:00:00

abstract：:Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting co...

journal_title：American journal of clinical dermatology

authors： Callender VD,St Surin-Lord S,Davis EC,Maclin M

更新日期：2011-04-01 00:00:00

abstract：:The etiologies of a variety of skin conditions associated with diabetes have not been fully explained. One possible etiological factor is diabetic microangiopathy, which is known to affect the eyes and kidneys in patients with diabetes. There are many mechanisms by which diabetes may cause microangiopathy. These inclu...

journal_title：American journal of clinical dermatology

authors： Ngo BT,Hayes KD,DiMiao DJ,Srinivasan SK,Huerter CJ,Rendell MS

更新日期：2005-01-01 00:00:00

abstract：:Chronic venous insufficiency (CVI) occurs in a relatively large proportion of the population and is associated with significant morbidity, high cost of healthcare, loss of productivity and reduced quality of life. Lower extremity ulcers related to CVI have been estimated to affect 0.2-1% of the population in developed...

journal_title：American journal of clinical dermatology

authors： Simka M,Majewski E

更新日期：2003-01-01 00:00:00

abstract：:Superficial fungal infections are chronic and recurring conditions. Tinea capitis is a scalp infection, primarily affecting prepubescent children. Ringworm infections, such as tinea corporis and tinea cruris, involve the glabrous skin. Tinea nigra is a rare mycotic infection that may be related to travel abroad. Piedr...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Cooper EA,Ryder JE,Nicol KA,Chow M,Chaudhry MM

更新日期：2004-01-01 00:00:00

abstract：:Long-term corticosteroid treatment is the most common secondary cause of bone loss. Patients treated with long-term corticosteroid therapy may develop osteopenia or osteoporosis, and many have fractures. It is difficult to predict which corticosteroid-treated patients will develop significant skeletal complications be...

journal_title：American journal of clinical dermatology

authors： Clarke BL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Many dermatologic disorders are known to adversely affect quality of life (QoL) in close relatives or partners of patients; however, it is unknown whether vitiligo impacts the QoL of family members. OBJECTIVE:The aim of this study was to identify the level and domains in which the QoL of partners/relatives ...

journal_title：American journal of clinical dermatology

authors： Bin Saif GA,Al-Balbeesi AO,Binshabaib R,Alsaad D,Kwatra SG,Alzolibani AA,Yosipovitch G

更新日期：2013-12-01 00:00:00

abstract：:Tumor therapy is not a common indication for the use of lasers, as it is in the treatment of benign vascular skin lesions, since many alternative treatment modalities exist. However, certain patients may benefit from laser therapy of premalignant and malignant skin tumors. Skin tumors can be treated by laser excision,...

journal_title：American journal of clinical dermatology

authors： Karrer S,Szeimies RM,Hohenleutner U,Landthaler M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:5% topical minoxidil solution has been widely used to stimulate new hair growth and help stop hair loss in men with androgenetic alopecia (AGA). However, it is not convenient for patients to continue applying the solution twice daily on a regular basis. Tretinoin is known to increase the percutaneous absorpt...

journal_title：American journal of clinical dermatology

authors： Shin HS,Won CH,Lee SH,Kwon OS,Kim KH,Eun HC

更新日期：2007-01-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) has been proposed as a treatment for toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS). A comprehensive search of the literature was conducted to examine the efficacy and safety of IVIg in TEN and SJS patients. Seventeen relevant articles (14 TEN, 3 SJS) were identif...

journal_title：American journal of clinical dermatology

authors： Mittmann N,Chan B,Knowles S,Cosentino L,Shear N

更新日期：2006-01-01 00:00:00

abstract：:Systemic sclerosis is an extremely variable disease in its manifestations and consequently, treatment needs to be individualized depending on the specific problems that each patient has. Limited scleroderma patients have a prolonged duration of Raynaud's phenomenon and puffy fingers before they develop any skin thicke...

journal_title：American journal of clinical dermatology

authors： Steen VD

更新日期：2001-01-01 00:00:00

abstract：:Solar, and particularly UV, radiation causes molecular and cellular damage with resultant histopathologic and clinical degenerative changes, leading in turn to photosensitivity, photo-aging, and skin cancer. While our bodies have some natural UV defenses, additional protection from the sun is essential, including sun ...

journal_title：American journal of clinical dermatology

authors： Gonzaga ER

更新日期：2009-01-01 00:00:00

abstract：:The objective of this article is to provide a brief, but critical, overview of the evidence related to complementary/alternative medicine (CAM) use, and to offer valid and useful information for dermatologists in clinical practice. Systematic literature searches were conducted on these databases: Medline, EMBASE, The ...

journal_title：American journal of clinical dermatology

authors： Ernst E,Pittler MH,Stevinson C

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Efforts have been recently made to investigate simple, objective, accurate, and reproducible methods of clinical/noninvasive assessment of nonsegmental vitiligo. However, studies have mostly considered quantitative or semiquantitative parameters, almost neglecting the purely qualitative appearance of vitilig...

journal_title：American journal of clinical dermatology

authors： Menchini G,Comacchi C,Cappugi P,Torchia D

更新日期：2013-02-01 00:00:00

abstract：:Topical pimecrolimus 1% cream (Elidel) [hereafter referred to as topical pimecrolimus] is a nonsteroidal alternative in the treatment of pediatric atopic dermatitis. In vehicle-controlled, short-term, continuous-use trials in pediatric patients with mild to moderate atopic dermatitis, topical pimecrolimus was effectiv...

journal_title：American journal of clinical dermatology

authors： Yang LP,Curran MP

更新日期：2010-01-01 00:00:00

abstract：:The family of toll-like receptors (TLRs) plays a central role in the cutaneous immune defense system. To date, different TLRs have been found on several major cell populations of the skin, such as keratinocytes, fibroblasts, antigen-presenting cells, and melanocytes. Activation of TLRs leads, via different intracellul...

journal_title：American journal of clinical dermatology

authors： Terhorst D,Kalali BN,Ollert M,Ring J,Mempel M

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:Topical application of the antibacterial agent metronidazole is effective in the treatment of moderate to severe rosacea, although its mechanism of action has yet to be clearly established. Metronidazole preparations (0.75 and 1% cream, 0.75% gel and 0.75% lotion) were significantly more effective than place...

journal_title：American journal of clinical dermatology

authors： McClellan KJ,Noble S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Information on the factors that influence treatment management decisions for psoriatic arthritis (PsA) is limited. OBJECTIVE:Our objective was to evaluate the impact of clinical specialty setting and geographic region on the management of patients with PsA in the USA. METHODS:LOOP was a multicenter, cross-...

journal_title：American journal of clinical dermatology

authors： Mease PJ,Liu C,Siegel E,Richmond H,Wu M,Chen L,Douglas K,Lockshin B

更新日期：2019-12-01 00:00:00

abstract：:After a marked decline in the number of syphilis cases in the context of AIDS prevention campaigns, a significant increase has been observed in states of the former Soviet Union since 1994. In recent years, outbreaks have also been reported in the US, Canada, and several European countries. The current epidemic in the...

journal_title：American journal of clinical dermatology

authors： Lautenschlager S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Videodermatoscopy is a non-invasive technique that allows in vivo skin observation at high magnifications. OBJECTIVE:The goal of this study was to determine if videodermatoscopy enhances diagnostic capability beyond standard clinical observation in three series of patients: one group of patients with overt ...

journal_title：American journal of clinical dermatology

authors： Lacarrubba F,Dall'Oglio F,Rita Nasca M,Micali G

更新日期：2004-01-01 00:00:00

abstract：:Recent advances in our understanding of the pathophysiology of atopic dermatitis (AD) have revealed that skin microbiome dysbiosis plays an important role in the disease. In this review, we describe how changes in the structure and function of the microbiome are involved in the pathogenesis of AD. We highlight recent ...

journal_title：American journal of clinical dermatology

authors： Li W,Yosipovitch G

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The relationship between psoriasis and vitiligo has not been previously confirmed, and we therefore aimed to investigate this association. METHODS:We conducted a search of the MEDLINE and EMBASE electronic databases on 22 January 2018 for case-control, cross-sectional, and cohort studies examining the assoc...

journal_title：American journal of clinical dermatology

authors： Yen H,Chi CC

更新日期：2019-02-01 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that regulate lipid, glucose, and amino acid metabolism. More recently, PPARs and corresponding ligands have been shown in skin and other organs to regulate important cellular functions, including cell proliferation and...

journal_title：American journal of clinical dermatology

authors： Sertznig P,Seifert M,Tilgen W,Reichrath J

更新日期：2008-01-01 00:00:00

abstract：:Eruptive melanocytic nevi (EMN) is a phenomenon characterized by the sudden onset of nevi. Our objective was to compile all published reports of EMN to identify possible precipitating factors and to evaluate the clinical appearance and course. We conducted a systematic bibliographic search and selected 93 articles, re...

journal_title：American journal of clinical dermatology

authors： Burian EA,Jemec GBE

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...

journal_title：American journal of clinical dermatology

authors： Lin CC,Lin HC,Chiu HW

更新日期：2019-06-01 00:00:00