The Role of the Microbiome and Microbiome-Derived Metabolites in Atopic Dermatitis and Non-Histaminergic Itch.

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2003-01-01 00:00:00

abstract：:Childhood-onset psoriasis affects approximately one-third of the psoriatic population. Among many potential treatments of childhood psoriasis, biological agents are emerging as a valuable option in the management of this disease. In Europe, etanercept has recently been approved for children aged 8 years and over. Data...

journal_title：American journal of clinical dermatology

authors： Bard S,Torchia D,Schachner LA

更新日期：2010-01-01 00:00:00

abstract：:Eruptive melanocytic nevi (EMN) is a phenomenon characterized by the sudden onset of nevi. Our objective was to compile all published reports of EMN to identify possible precipitating factors and to evaluate the clinical appearance and course. We conducted a systematic bibliographic search and selected 93 articles, re...

journal_title：American journal of clinical dermatology

authors： Burian EA,Jemec GBE

更新日期：2019-10-01 00:00:00

abstract：:Microdermabrasion is a simple, safe, office cosmetic procedure in which aluminum oxide crystals or other abrasive substances are blown onto the face, then vacuumed off, using a single handpiece. This procedure has rapidly become widely utilized for a variety of cosmetic objectives, including the improvement of photoag...

journal_title：American journal of clinical dermatology

authors： Spencer JM

更新日期：2005-01-01 00:00:00

abstract：:A 46-year-old man developed Stevens-Johnson syndrome and toxic epidermal necrolysis overlap, with severe localized denudation of the skin on the head and neck, following radiotherapy and oral temozolomide therapy for cranial glioblastoma multiforme. He also had a primary malignant fibrous histiocytoma of the thigh tha...

journal_title：American journal of clinical dermatology

authors： Sarma N

更新日期：2009-01-01 00:00:00

abstract：:Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting co...

journal_title：American journal of clinical dermatology

authors： Callender VD,St Surin-Lord S,Davis EC,Maclin M

更新日期：2011-04-01 00:00:00

abstract：:Subcutaneous adalimumab (Humira®) is a tumour necrosis factor-α blocker that is the only approved agent for the treatment of moderate to severe hidradenitis suppurativa (HS) in several countries worldwide. This article reviews the clinical efficacy and safety of subcutaneous adalimumab in patients with moderate to sev...

journal_title：American journal of clinical dermatology

authors： Kim ES,Garnock-Jones KP,Keam SJ

更新日期：2016-10-01 00:00:00

abstract：:Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has ...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Carviel J,Abramovits W

更新日期：2017-02-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) has been proposed as a treatment for toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS). A comprehensive search of the literature was conducted to examine the efficacy and safety of IVIg in TEN and SJS patients. Seventeen relevant articles (14 TEN, 3 SJS) were identif...

journal_title：American journal of clinical dermatology

authors： Mittmann N,Chan B,Knowles S,Cosentino L,Shear N

更新日期：2006-01-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2002-01-01 00:00:00

abstract：:At least 20 clinically relevant factors affect percutaneous absorption of drugs and chemicals: relevant physico-chemical properties, vehicle/formulation, drug exposure conditions (dose, duration, surface area, exposure frequency), skin appendages (hair follicles, glands) as sub-anatomical pathways, skin application si...

journal_title：American journal of clinical dermatology

authors： Law RM,Ngo MA,Maibach HI

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Cutaneous lichen planus (CLP) is an inflammatory dermatosis. Its chronic relapsing course and frequently spontaneous regression hamper the assessment of treatment effectiveness. OBJECTIVE:To evaluate the efficacy of available treatment modalities for CLP. DATA SOURCES:PubMed, Cochrane Central Register of C...

journal_title：American journal of clinical dermatology

authors： Atzmony L,Reiter O,Hodak E,Gdalevich M,Mimouni D

更新日期：2016-02-01 00:00:00

abstract：:Autoimmune bullous diseases (AIBD), including pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, and pemphigoid gestationis, pose significant therapeutic challenges, especially in pregnant and post-partum breastfeeding patients or those planning to conceive. Data on the safety ...

journal_title：American journal of clinical dermatology

authors： Kushner CJ,Concha JSS,Werth VP

更新日期：2018-06-01 00:00:00

abstract：:Spinosad 0.9% suspension is a topical treatment for head-lice infestation (pediculosis capitis) that has been approved in the US as a prescription medicine. Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine ...

journal_title：American journal of clinical dermatology

authors： McCormack PL

更新日期：2011-10-01 00:00:00

abstract：:Photochemotherapy with methoxsalen (8-methoxypsoralen) and long wavelength ultraviolet (UV) radiation (referred to as 'PUVA' for psoralen plus UVA) is commonly used to treat psoriasis and vitiligo. These vastly different diseases respond to the therapy by different mechanisms even though the immediate effects of the t...

journal_title：American journal of clinical dermatology

authors： Gasparro FP

更新日期：2000-11-01 00:00:00

abstract：:Long-term corticosteroid treatment is the most common secondary cause of bone loss. Patients treated with long-term corticosteroid therapy may develop osteopenia or osteoporosis, and many have fractures. It is difficult to predict which corticosteroid-treated patients will develop significant skeletal complications be...

journal_title：American journal of clinical dermatology

authors： Clarke BL

更新日期：2012-06-01 00:00:00

abstract：:Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is important in the hematological and nervous systems, and it has a complex relationship with the skin. Altered cobalamin levels can lead to dermatological manifestations, which may indicate a deficiency or excess of this vitamin. The biochemistry a...

journal_title：American journal of clinical dermatology

authors： Brescoll J,Daveluy S

更新日期：2015-02-01 00:00:00

abstract：:Seborrheic dermatitis (SD) is characterized by erythematous pruritic patches and plaques with greasy scale that occur in sebaceous areas. It is common, affecting up to 3% of the population. Past treatments have relied on a wide variety of anti-inflammatory and antifungal agents, but corticosteroids have limited use be...

journal_title：American journal of clinical dermatology

authors： Cook BA,Warshaw EM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...

journal_title：American journal of clinical dermatology

authors： Lin CC,Lin HC,Chiu HW

更新日期：2019-06-01 00:00:00

abstract：:Erythema nodosum (EN) is the most common form of panniculitis. It is characterized by erythematous, raised, tender nodules that usually occur bilaterally on the extensor surfaces of the lower extremities. EN is associated with many underlying conditions including infection, sarcoidosis, malignancy, and pregnancy. Its ...

journal_title：American journal of clinical dermatology

authors： Acosta KA,Haver MC,Kelly B

更新日期：2013-06-01 00:00:00

abstract：:Superficial fungal infections are chronic and recurring conditions. Tinea capitis is a scalp infection, primarily affecting prepubescent children. Ringworm infections, such as tinea corporis and tinea cruris, involve the glabrous skin. Tinea nigra is a rare mycotic infection that may be related to travel abroad. Piedr...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Cooper EA,Ryder JE,Nicol KA,Chow M,Chaudhry MM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Many dermatologic disorders are known to adversely affect quality of life (QoL) in close relatives or partners of patients; however, it is unknown whether vitiligo impacts the QoL of family members. OBJECTIVE:The aim of this study was to identify the level and domains in which the QoL of partners/relatives ...

journal_title：American journal of clinical dermatology

authors： Bin Saif GA,Al-Balbeesi AO,Binshabaib R,Alsaad D,Kwatra SG,Alzolibani AA,Yosipovitch G

更新日期：2013-12-01 00:00:00

abstract：:Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant genodermatosis with malignant potential characterized by cutaneous and extracutaneous stigmata. Aberrations in the folliculin (FLCN) gene, which is located on chromosome 17, have been discovered in individuals with this condition. Over 150 unique mutations have be...

journal_title：American journal of clinical dermatology

authors： Tong Y,Schneider JA,Coda AB,Hata TR,Cohen PR

更新日期：2018-02-01 00:00:00

abstract：:Melanoma is a malignancy of pigment-producing cells that is driven by a variety of genetic mutations and aberrations. In most cases, this leads to upregulation of the mitogen-activated protein kinase (MAPK) pathway through activating mutations of upstream mediators of the pathway including BRAF and NRAS. With the adve...

journal_title：American journal of clinical dermatology

authors： Akabane H,Sullivan RJ

更新日期：2016-02-01 00:00:00

abstract：:Airbags are restraining safety devices, but their activation may sometimes induce injuries during road accidents. Rapid deceleration due to an impact causes the ignition of a sodium azide cartridge, which releases nitrogen gas to inflate the nylon rubber bag. Numerous high-temperature gases, sodium hydroxide, carbon d...

journal_title：American journal of clinical dermatology

authors： Corazza M,Trincone S,Virgili A

更新日期：2004-01-01 00:00:00

abstract：:Trigeminal trophic syndrome (TTS) is the historic name for neuropathic self-induced facial ulceration from abnormal sensory symptoms leading to uncontrolled scratching. Anatomic co-localization of sensory loss (numbness) plus neuropathic itch and pain permits painless scratching. If the itch is severe, some patients w...

journal_title：American journal of clinical dermatology

authors： Curtis AR,Oaklander AL,Johnson A,Yosipovitch G

更新日期：2012-04-01 00:00:00

abstract：SIGNIFICANCE:Psoriasis, a common immune-mediated disease, affects approximately 2% of the population worldwide. Sudden sensorineural hearing loss (SSNHL) might be a manifestation of systemic vascular involvement in autoimmune disease. However, to the best of our knowledge, there is no systematic English-language examin...

journal_title：American journal of clinical dermatology

authors： Yen YC,Lin YS,Weng SF,Lai FJ

更新日期：2015-06-01 00:00:00

abstract：:Aggressive digital papillary adenocarcinoma (ADPAC) is a rare cutaneous malignant tumor. We report on a 42-year-old man presenting with a nontender firm nodule on his right thumb that had been present for 3 years. The lesion clinically resembled an acquired digital fibrokeratoma, but was found to be an ADPAC after pat...

journal_title：American journal of clinical dermatology

authors： Chi CC,Kuo TT,Wang SH

更新日期：2007-01-01 00:00:00

abstract：:We provide a guide for dermatologists to follow if they encounter patients with a rash and clinical history suspicious of Zika virus infection, including diagnostic testing and management options. We also provide an illustrative case report of a patient from Brazil who was diagnosed with Zika virus infection after pre...

journal_title：American journal of clinical dermatology

authors： He A,Brasil P,Siqueira AM,Calvet GA,Kwatra SG

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Videodermatoscopy is a non-invasive technique that allows in vivo skin observation at high magnifications. OBJECTIVE:The goal of this study was to determine if videodermatoscopy enhances diagnostic capability beyond standard clinical observation in three series of patients: one group of patients with overt ...

journal_title：American journal of clinical dermatology

authors： Lacarrubba F,Dall'Oglio F,Rita Nasca M,Micali G

更新日期：2004-01-01 00:00:00