The Emerging Zika Virus Threat: A Guide for Dermatologists.

abstract：:The family of toll-like receptors (TLRs) plays a central role in the cutaneous immune defense system. To date, different TLRs have been found on several major cell populations of the skin, such as keratinocytes, fibroblasts, antigen-presenting cells, and melanocytes. Activation of TLRs leads, via different intracellul...

journal_title：American journal of clinical dermatology

authors： Terhorst D,Kalali BN,Ollert M,Ring J,Mempel M

更新日期：2010-01-01 00:00:00

abstract：:Itch, also known as pruritus, is the major symptom in skin diseases with a variety of etiologies and pathophysiologies. Significant progress has been achieved in understanding the pathophysiology of itch in the last 5 years. Neurophysiological experiments in humans and animals have revealed that itch is carried by spe...

journal_title：American journal of clinical dermatology

authors： Yosipovitch G,Fleischer A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Videodermatoscopy is a non-invasive technique that allows in vivo skin observation at high magnifications. OBJECTIVE:The goal of this study was to determine if videodermatoscopy enhances diagnostic capability beyond standard clinical observation in three series of patients: one group of patients with overt ...

journal_title：American journal of clinical dermatology

authors： Lacarrubba F,Dall'Oglio F,Rita Nasca M,Micali G

更新日期：2004-01-01 00:00:00

abstract：:A recent study demonstrated an association between psoriasis and dilated cardiomyopathy. Tumour necrosis factor alpha (TNFalpha) may be involved in the pathogenesis of dilated cardiomyopathy and therefore, anti-TNFalpha agents may play a role in the treatment of dilated cardiomyopathy. The case of a 51-year-old woman ...

journal_title：American journal of clinical dermatology

authors： De Simone C,Carbone A,Caldarola G

更新日期：2010-01-01 00:00:00

abstract：:Coccidioidomycosis is an endemic mycosis of the southern United States, Northern Mexico, and South America. Primary cutaneous coccidioidomycosis, despite being a very rare clinical presentation, has shown an increasing incidence. An extensive literature search for cutaneous coccidioidomycosis cases was performed using...

journal_title：American journal of clinical dermatology

authors： Reyna-Rodríguez IL,Ocampo-Candiani J,Chavez-Alvarez S

更新日期：2020-10-01 00:00:00

abstract：:Aggressive digital papillary adenocarcinoma (ADPAC) is a rare cutaneous malignant tumor. We report on a 42-year-old man presenting with a nontender firm nodule on his right thumb that had been present for 3 years. The lesion clinically resembled an acquired digital fibrokeratoma, but was found to be an ADPAC after pat...

journal_title：American journal of clinical dermatology

authors： Chi CC,Kuo TT,Wang SH

更新日期：2007-01-01 00:00:00

abstract：:We report a 47-year-old man with Wilson disease who developed bullous lesions on the trunk and extremities after 20 years of penicillamine treatment. The histologic and immunofluorescence findings were diagnostic of bullous pemphigoid. When penicillamine was replaced by zinc sulfate, the patient's bullous skin lesions...

journal_title：American journal of clinical dermatology

authors： Popadic S,Skiljevic D,Medenica L

更新日期：2009-01-01 00:00:00

abstract：:A rapidly increasing number of people visit dermatologists for the prevention and treatment of aging skin. Sun avoidance and sunscreen use are widely accepted strategies of primary prevention against photoaging. Convincing evidence shows that topical application of retinoids has an effect on reversing, at least partia...

journal_title：American journal of clinical dermatology

authors： Antoniou C,Kosmadaki MG,Stratigos AJ,Katsambas AD

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is an allergic disorder caused by both immunological dysregulation and epidermal barrier defect. Several studies have investigated the association between AD and mental health disorders. Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental conditions characte...

journal_title：American journal of clinical dermatology

authors： Billeci L,Tonacci A,Tartarisco G,Ruta L,Pioggia G,Gangemi S

更新日期：2015-10-01 00:00:00

abstract：:Subcutaneous adalimumab (Humira®) is a tumour necrosis factor-α blocker that is the only approved agent for the treatment of moderate to severe hidradenitis suppurativa (HS) in several countries worldwide. This article reviews the clinical efficacy and safety of subcutaneous adalimumab in patients with moderate to sev...

journal_title：American journal of clinical dermatology

authors： Kim ES,Garnock-Jones KP,Keam SJ

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Topical coal tar is a well known and effective treatment for psoriasis, but the messiness, staining, odor, and inconvenience associated with its use make patient satisfaction and compliance a challenge. OBJECTIVE:To determine the efficacy, patient tolerability, and cosmetic acceptability of a new topical li...

journal_title：American journal of clinical dermatology

authors： Alora-Palli MB,Perkins AC,Van Cott A,Kimball AB

更新日期：2010-01-01 00:00:00

abstract：:Topical retapamulin (Altabax, Altargo) is the first pleuromutilin antibacterial approved for the treatment of uncomplicated superficial skin infections caused by Staphylococcus aureus (excluding methicillin-resistant S. aureus [MRSA]) and Streptococcus pyogenes in patients aged > or = 9 months. In the EU, retapamulin ...

journal_title：American journal of clinical dermatology

authors： Yang LP,Keam SJ

更新日期：2008-01-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:5% topical minoxidil solution has been widely used to stimulate new hair growth and help stop hair loss in men with androgenetic alopecia (AGA). However, it is not convenient for patients to continue applying the solution twice daily on a regular basis. Tretinoin is known to increase the percutaneous absorpt...

journal_title：American journal of clinical dermatology

authors： Shin HS,Won CH,Lee SH,Kwon OS,Kim KH,Eun HC

更新日期：2007-01-01 00:00:00

abstract：:Viral skin infections are common findings in organ transplant recipients. The most important etiological agents are the group of human herpesviruses (HHV), human papillomaviruses (HPV), and molluscum contagiosum virus. HHV that are important in this group of patients are herpes simplex virus (HSV) types 1 and 2, varic...

journal_title：American journal of clinical dermatology

authors： Tan HH,Goh CL

更新日期：2006-01-01 00:00:00

abstract：:Mycobacterial organisms have re-emerged as an important cause of infectious disease worldwide. Both tuberculosis and nontuberculous mycobacterial infections remain endemic in many parts of the world and are becoming more common in patients with iatrogenic immunosuppression and HIV infection. The nontuberculous mycobac...

journal_title：American journal of clinical dermatology

authors： Elston D

更新日期：2009-01-01 00:00:00

abstract：:This review summarizes results from major recent trials regarding novel therapeutic agents in melanoma. The topics discussed include targeted therapy with BRAF (V-RAF murine sarcoma viral oncogene homolog B) inhibitors (vemurafenib and dabrafenib), MEK (mitogen-activated protein kinase kinase) inhibitors (trametinib),...

journal_title：American journal of clinical dermatology

authors： Karimkhani C,Gonzalez R,Dellavalle RP

更新日期：2014-08-01 00:00:00

abstract：:Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting co...

journal_title：American journal of clinical dermatology

authors： Callender VD,St Surin-Lord S,Davis EC,Maclin M

更新日期：2011-04-01 00:00:00

abstract：:After a marked decline in the number of syphilis cases in the context of AIDS prevention campaigns, a significant increase has been observed in states of the former Soviet Union since 1994. In recent years, outbreaks have also been reported in the US, Canada, and several European countries. The current epidemic in the...

journal_title：American journal of clinical dermatology

authors： Lautenschlager S

更新日期：2006-01-01 00:00:00

abstract：:Non-infectious granulomatous diseases of the skin are a broad group of distinct reactive inflammatory conditions that share important similarities. As a group, they are relatively difficult to diagnose and distinguish both clinically as well as histologically. Many of these disorders have significant associations with...

journal_title：American journal of clinical dermatology

authors： Hawryluk EB,Izikson L,English JC 3rd

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Probiotic, prebiotic, and synbiotic supplementation is becoming more prevalent nowadays. Clinical studies have demonstrated some of the medical benefits of probiotics, prebiotics, and synbiotics within dermatology but an evidence-based review of their effects in adults is needed. OBJECTIVE:The aim of this s...

journal_title：American journal of clinical dermatology

authors： Notay M,Foolad N,Vaughn AR,Sivamani RK

更新日期：2017-12-01 00:00:00

abstract：UNLABELLED:Topical application of the antibacterial agent metronidazole is effective in the treatment of moderate to severe rosacea, although its mechanism of action has yet to be clearly established. Metronidazole preparations (0.75 and 1% cream, 0.75% gel and 0.75% lotion) were significantly more effective than place...

journal_title：American journal of clinical dermatology

authors： McClellan KJ,Noble S

更新日期：2000-05-01 00:00:00

abstract：:Long-term corticosteroid treatment is the most common secondary cause of bone loss. Patients treated with long-term corticosteroid therapy may develop osteopenia or osteoporosis, and many have fractures. It is difficult to predict which corticosteroid-treated patients will develop significant skeletal complications be...

journal_title：American journal of clinical dermatology

authors： Clarke BL

更新日期：2012-06-01 00:00:00

abstract：:Lichen planus is a relatively common disorder of the stratified squamous epithelia. Most dental and medical practitioners see patients with lichen planus, but not all are recognized as having the disease. Patients with lichen planus may have concomitant involvement of the disease in multiple sites. Oral lichen planus ...

journal_title：American journal of clinical dermatology

authors： Scully C,Eisen D,Carrozzo M

更新日期：2000-09-01 00:00:00

abstract：:We report a typical case of hematidrosis in a Chinese girl who had experienced frequent bleeding episodes for more than 3 years. During hospitalization, spontaneous bleeding from her intact skin was witnessed by our staff on more than 20 occasions. Characteristically, bloody droplets from the intact skin contained all...

journal_title：American journal of clinical dermatology

authors： Wang Z,Yu Z,Su J,Cao L,Zhao X,Bai X,Zhan S,Wu T,Jin L,Zhou P,Ruan C

更新日期：2010-12-01 00:00:00

abstract：:Granuloma annulare (GA) is a chronic inflammatory disease of unknown etiology characterized by the development of plaques preferentially localized to the distal extremities. Spontaneous remission and relapses are quite common and the course of GA is not easy to predict. Moreover, most therapeutic regimens have been us...

journal_title：American journal of clinical dermatology

authors： Murdaca G,Colombo BM,Barabino G,Caiti M,Cagnati P,Puppo F

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Cutaneous lichen planus (CLP) is an inflammatory dermatosis. Its chronic relapsing course and frequently spontaneous regression hamper the assessment of treatment effectiveness. OBJECTIVE:To evaluate the efficacy of available treatment modalities for CLP. DATA SOURCES:PubMed, Cochrane Central Register of C...

journal_title：American journal of clinical dermatology

authors： Atzmony L,Reiter O,Hodak E,Gdalevich M,Mimouni D

更新日期：2016-02-01 00:00:00

abstract：:Rituximab is a chimeric monoclonal antibody that selectively binds to the CD20 molecule on B cells, resulting in their lysis. In autoimmune blistering diseases, the auto-antibody-producing B cells are destroyed and auto-antibody levels are reduced or eliminated. In the majority of patients, rituximab produces rapid cl...

journal_title：American journal of clinical dermatology

authors： Ahmed AR,Shetty S

更新日期：2015-06-01 00:00:00

abstract：:Spinosad 0.9% suspension is a topical treatment for head-lice infestation (pediculosis capitis) that has been approved in the US as a prescription medicine. Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine ...

journal_title：American journal of clinical dermatology

authors： McCormack PL

更新日期：2011-10-01 00:00:00

abstract：:Systemic sclerosis is an extremely variable disease in its manifestations and consequently, treatment needs to be individualized depending on the specific problems that each patient has. Limited scleroderma patients have a prolonged duration of Raynaud's phenomenon and puffy fingers before they develop any skin thicke...

journal_title：American journal of clinical dermatology

authors： Steen VD

更新日期：2001-01-01 00:00:00