Fragrance contact allergy: a clinical review.

abstract：BACKGROUND:A few studies in psoriasis vulgaris patients have reported changes suggesting red blood cell (RBC) damage is linked to neutrophil activation, oxidative stress, and psoriasis worsening. OBJECTIVE:The aim of this study was to evaluate erythroid disturbances in Portuguese psoriasis vulgaris patients, before, d...

journal_title：American journal of clinical dermatology

authors： Coimbra S,Oliveira H,Reis F,Belo L,Rocha S,Quintanilha A,Figueiredo A,Teixeira F,Castro E,Rocha-Pereira P,Santos-Silva A

更新日期：2012-02-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare but aggressive cutaneous tumor with a predilection for the head and neck of elderly Caucasian patients. Although much less common than melanoma, MCC has higher rates of sentinel lymph node involvement, local and regional recurrences, and mortality. The majority of MCC cases have b...

journal_title：American journal of clinical dermatology

authors： Brummer GC,Bowen AR,Bowen GM

更新日期：2016-02-01 00:00:00

abstract：:Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...

journal_title：American journal of clinical dermatology

authors： Layton AM

更新日期：2001-01-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) has been proposed as a treatment for toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS). A comprehensive search of the literature was conducted to examine the efficacy and safety of IVIg in TEN and SJS patients. Seventeen relevant articles (14 TEN, 3 SJS) were identif...

journal_title：American journal of clinical dermatology

authors： Mittmann N,Chan B,Knowles S,Cosentino L,Shear N

更新日期：2006-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF)-α inhibitors are an alternative to oral systemic therapies for psoriasis. Data regarding the safety of TNF-α inhibitors from randomized clinical trials may not fully reflect the effects on the clinic patient population receiving the therapy, but other sources of information are available. W...

journal_title：American journal of clinical dermatology

authors： Semble AL,Davis SA,Feldman SR

更新日期：2014-02-01 00:00:00

abstract：:Granular parakeratosis (GP) is a rare, idiopathic, and benign skin condition that presents classically as erythematous to brown hyperkeratotic papules that can coalesce into plaques. Axillary GP was initially observed by Northcutt and colleagues and has since been described in various other areas of the body including...

journal_title：American journal of clinical dermatology

authors： Ding CY,Liu H,Khachemoune A

更新日期：2015-12-01 00:00:00

abstract：:For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy. The potent anti-inflammatory properties of thal...

journal_title：American journal of clinical dermatology

authors： Pelle MT,Werth VP

更新日期：2003-01-01 00:00:00

abstract：:Hyperhidrosis is a common and distressing condition involving increased production of sweat. A variety of treatment modalities are used to try to control or reduce sweating. Sweat is secreted by eccrine glands innervated by cholinergic fibers from the sympathetic nervous system. Primary hyperhidrosis most commonly aff...

journal_title：American journal of clinical dermatology

authors： Connolly M,de Berker D

更新日期：2003-01-01 00:00:00

abstract：:Black hairy tongue (BHT) is a benign condition commonly found among people who smoke, have poor oral hygiene, are immunocompromised, or have a medical condition limiting their ability to practice good oral hygiene. Though this condition is harmless, patients need to be educated on etiology as many common medications a...

journal_title：American journal of clinical dermatology

authors： Schlager E,St Claire C,Ashack K,Khachemoune A

更新日期：2017-08-01 00:00:00

abstract：:Superficial fungal infections are chronic and recurring conditions. Tinea capitis is a scalp infection, primarily affecting prepubescent children. Ringworm infections, such as tinea corporis and tinea cruris, involve the glabrous skin. Tinea nigra is a rare mycotic infection that may be related to travel abroad. Piedr...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Cooper EA,Ryder JE,Nicol KA,Chow M,Chaudhry MM

更新日期：2004-01-01 00:00:00

abstract：:Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is important in the hematological and nervous systems, and it has a complex relationship with the skin. Altered cobalamin levels can lead to dermatological manifestations, which may indicate a deficiency or excess of this vitamin. The biochemistry a...

journal_title：American journal of clinical dermatology

authors： Brescoll J,Daveluy S

更新日期：2015-02-01 00:00:00

abstract：:In women, acne can be successfully treated with oral contraceptives. This article focuses on the results of clinical studies on the treatment of acne with oral contraceptives. From the literature, 12 such studies could be traced over the last 10 years. Most of the studies were multicenter, randomized, and double blind...

journal_title：American journal of clinical dermatology

authors： van Vloten WA,Sigurdsson V

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The relationship between psoriasis and vitiligo has not been previously confirmed, and we therefore aimed to investigate this association. METHODS:We conducted a search of the MEDLINE and EMBASE electronic databases on 22 January 2018 for case-control, cross-sectional, and cohort studies examining the assoc...

journal_title：American journal of clinical dermatology

authors： Yen H,Chi CC

更新日期：2019-02-01 00:00:00

abstract：:Granuloma annulare (GA) is a chronic inflammatory disease of unknown etiology characterized by the development of plaques preferentially localized to the distal extremities. Spontaneous remission and relapses are quite common and the course of GA is not easy to predict. Moreover, most therapeutic regimens have been us...

journal_title：American journal of clinical dermatology

authors： Murdaca G,Colombo BM,Barabino G,Caiti M,Cagnati P,Puppo F

更新日期：2010-12-01 00:00:00

abstract：:There is a high unmet clinical need for new and better treatments in acne vulgaris. Propionibacterium acnes has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity, keratinocytes and sebaceous glands of the pilosebaceous follicle. The role of P. acnes in acne confers legit...

journal_title：American journal of clinical dermatology

authors： Simonart T

更新日期：2013-12-01 00:00:00

abstract：:Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid hormones, and porphyrins. The topical use ...

journal_title：American journal of clinical dermatology

authors： Ebner F,Heller A,Rippke F,Tausch I

更新日期：2002-01-01 00:00:00

abstract：:Aging of the skin is associated with skin thinning, atrophy, dryness, wrinkling, and delayed wound healing. These undesirable aging effects are exacerbated by declining estrogen levels in postmenopausal women. With the rise in interest in long-term postmenopausal skin management, studies on the restorative benefits th...

journal_title：American journal of clinical dermatology

authors： Shu YY,Maibach HI

更新日期：2011-10-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2002-01-01 00:00:00

abstract：:Skin disorders are the most common adverse reactions attributed to drugs. Any skin disorder can be imitated, induced or aggravated by drugs. To help you keep up-to-date with the very latest skin reactions occurring with both new and established drugs, this section of the journal brings you information selected from th...

journal_title：American journal of clinical dermatology

authors：

更新日期：2003-01-01 00:00:00

abstract：:Non-infectious granulomatous diseases of the skin are a broad group of distinct reactive inflammatory conditions that share important similarities. As a group, they are relatively difficult to diagnose and distinguish both clinically as well as histologically. Many of these disorders have significant associations with...

journal_title：American journal of clinical dermatology

authors： Hawryluk EB,Izikson L,English JC 3rd

更新日期：2010-01-01 00:00:00

abstract：:The connection between the brain and the skin is more than a physiologic fact. Skin conditions can impose great effects on every field in the patients' lives. Reciprocally, skin diseases can be evoked by psychological problems. A psychodermatology clinic is the format that enables dermatology patients to receive a com...

journal_title：American journal of clinical dermatology

authors： Orion E,Feldman B,Ronni W,Orit BA

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Many dermatologic disorders are known to adversely affect quality of life (QoL) in close relatives or partners of patients; however, it is unknown whether vitiligo impacts the QoL of family members. OBJECTIVE:The aim of this study was to identify the level and domains in which the QoL of partners/relatives ...

journal_title：American journal of clinical dermatology

authors： Bin Saif GA,Al-Balbeesi AO,Binshabaib R,Alsaad D,Kwatra SG,Alzolibani AA,Yosipovitch G

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is not well characterized. PURPOSE:The objective of this st...

journal_title：American journal of clinical dermatology

authors： Al-Dabagh A,Davis SA,Kinney MA,Huang K,Feldman SR

更新日期：2013-06-01 00:00:00

abstract：:At least 20 clinically relevant factors affect percutaneous absorption of drugs and chemicals: relevant physico-chemical properties, vehicle/formulation, drug exposure conditions (dose, duration, surface area, exposure frequency), skin appendages (hair follicles, glands) as sub-anatomical pathways, skin application si...

journal_title：American journal of clinical dermatology

authors： Law RM,Ngo MA,Maibach HI

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Videodermatoscopy is a non-invasive technique that allows in vivo skin observation at high magnifications. OBJECTIVE:The goal of this study was to determine if videodermatoscopy enhances diagnostic capability beyond standard clinical observation in three series of patients: one group of patients with overt ...

journal_title：American journal of clinical dermatology

authors： Lacarrubba F,Dall'Oglio F,Rita Nasca M,Micali G

更新日期：2004-01-01 00:00:00

abstract：:Long-term corticosteroid treatment is the most common secondary cause of bone loss. Patients treated with long-term corticosteroid therapy may develop osteopenia or osteoporosis, and many have fractures. It is difficult to predict which corticosteroid-treated patients will develop significant skeletal complications be...

journal_title：American journal of clinical dermatology

authors： Clarke BL

更新日期：2012-06-01 00:00:00

abstract：:Melanoma is a malignancy of pigment-producing cells that is driven by a variety of genetic mutations and aberrations. In most cases, this leads to upregulation of the mitogen-activated protein kinase (MAPK) pathway through activating mutations of upstream mediators of the pathway including BRAF and NRAS. With the adve...

journal_title：American journal of clinical dermatology

authors： Akabane H,Sullivan RJ

更新日期：2016-02-01 00:00:00

abstract：:Darier's disease is a rare cutaneous disease with an autosomal dominant mode of inheritance. Greasy papules and plaques arise on the seborrheic areas and in the flexures and almost all patients have nail abnormalities. Acantholysis and dyskeratosis are the typical histological findings. The underlying defect is a resu...

journal_title：American journal of clinical dermatology

authors： Cooper SM,Burge SM

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Dementia is a syndrome that involves the deterioration of several higher mental functions in advanced age, and psoriasis is an autoimmune disease characterized by skin plaque. Epidemiological studies have indicated an association between dementia and psoriasis; however, to date, no studies in Asia have repor...

journal_title：American journal of clinical dermatology

authors： Lin CC,Lin HC,Chiu HW

更新日期：2019-06-01 00:00:00

abstract：:Itch, also known as pruritus, is the major symptom in skin diseases with a variety of etiologies and pathophysiologies. Significant progress has been achieved in understanding the pathophysiology of itch in the last 5 years. Neurophysiological experiments in humans and animals have revealed that itch is carried by spe...

journal_title：American journal of clinical dermatology

authors： Yosipovitch G,Fleischer A

更新日期：2003-01-01 00:00:00