Effects of single pill-based combination therapy of amlodipine and atorvastatin on within-visit blood pressure variability and parameters of renal and vascular function in hypertensive patients with chronic kidney disease.

abstract：:Periodontal remodeling and alveolar bone resorption and formation play essential roles during orthodontic tooth movement (OTM). In the process, human periodontal ligament cells (HPDLCs) sense and respond to orthodontic forces, contributing to the alveolar bone formation. However, the underlying mechanism in this proce...

journal_title：BioMed research international

authors： Yang Y,Wang BK,Chang ML,Wan ZQ,Han GL

更新日期：2018-11-05 00:00:00

abstract：:Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hy...

journal_title：BioMed research international

authors： Hünlich M,Lubos E,Beuthner BE,Puls M,Bleckmann A,Beißbarth T,Tichelbäcker T,Rudolph V,Baldus S,Schäfer U,Treede H,Von Bardeleben RS,Blankenberg S,Schillinger W

更新日期：2018-03-14 00:00:00

abstract：:Lung cancer is the leading cause of cancer-related death worldwide, and the most common histologic subtype is lung adenocarcinoma (LUAD). Due to the significant mortality and morbidity rates among patients with LUAD, the identification of novel biomarkers to guide diagnosis, prognosis, and therapy is urgent. Guanosine...

journal_title：BioMed research international

authors： Zhang Z,Wang J,Mao J,Li F,Chen W,Wang W

更新日期：2020-10-19 00:00:00

abstract：Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

journal_title：BioMed research international

authors： Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

更新日期：2020-08-14 00:00:00

abstract：:Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...

journal_title：BioMed research international

authors： Haass NK,Nassif N,McGowan EM

更新日期：2015-01-01 00:00:00

abstract：:Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carrier (NLC) to produce...

journal_title：BioMed research international

authors： Foong JN,Selvarajah GT,Rasedee A,Rahman HS,How CW,Beh CY,Teo GY,Ku CL

更新日期：2018-10-15 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:It is believed that the vasopressinergic system plays an important role in the pathogenesis of chronic kidney disease (CKD). The aim of this study was to evaluate the effect of CKD on changes in vasopressin system expression in the kidney cortex in rats with nephrectomy. The study was performed on 4 groups of Sprague ...

journal_title：BioMed research international

authors： Czarzasta K,Cudnoch-Jedrzejewska A,Niemczyk L,Wrzesien R,Tkaczyk M,Puchalska L,Saracyn M,Zmudzki W,Niemczyk S

更新日期：2018-06-14 00:00:00

abstract：:The characteristics of FDG uptake in the physiologic and malignant nasopharynx were investigated in the paper which was correlated with either pathologic findings or clinical follow-up. Three patients had pathologically established nasopharyngeal malignancy. In the 3 nasopharyngeal malignancies, 2 had diffusely and ex...

journal_title：BioMed research international

authors： Ma C,Zou R,Huo Y,Chen S,Wang S,Wu S,Ye Z,Wu Z,Fang F,Wang H

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Lipoprotein-associated phospholipase A2 (Lp-PLA2), a marker of vascular inflammation, is associated with cardiovascular disease. This prospective study of an inception cohort aimed to investigate whether the level of Lp-PLA2 is associated with subclinical atherosclerosis in patients with rheumatoid arthritis ...

journal_title：BioMed research international

authors： Södergren A,Karp K,Bengtsson C,Möller B,Rantapää-Dahlqvist S,Wållberg-Jonsson S

更新日期：2015-01-01 00:00:00

abstract：:A role of pro- and antioxidants for reducing rectal cancer (RC) incidence in operative, preoperative, and postoperative treatments is still disputable and controversial. The redox state of venous blood and tissues of blood vessels of 60 patients with RC (T2-4N0-2M0G2) and 20 donors is studied by means of the conventio...

journal_title：BioMed research international

authors： Burlaka AP,Vovk AV,Burlaka AA,Gafurov MR,Iskhakova KB,Lukin SN

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...

journal_title：BioMed research international

authors： Deylam Salehi M,Ferdosi-Shahandashti E,Yahyapour Y,Khafri S,Pournajaf A,Rajabnia R

更新日期：2017-01-01 00:00:00

abstract：Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

journal_title：BioMed research international

authors： Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

更新日期：2020-09-23 00:00:00

abstract：:Due to expanding applications of positron emission tomography (PET) there is a demand for developing new techniques to introduce fluorine-18 (t 1/2 = 109.8 min). Considering that most novel PET tracers are sensitive biomolecules and that direct introduction of fluorine-18 often needs harsh conditions, the insertion of...

journal_title：BioMed research international

authors： Kettenbach K,Schieferstein H,Ross TL

更新日期：2014-01-01 00:00:00

abstract：:Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC pr...

journal_title：BioMed research international

authors： Lahner M,Ull C,Hagen M,von Schulze Pellengahr C,Daniilidis K,von Engelhardt LV,Lahner N,Teske W

更新日期：2018-05-08 00:00:00

abstract：Methods:circRNA expression was analysed in six cerebrospinal fluid (CSF) samples from three patients of the infectious and noninfectious phases using an Arraystar Human circRNA Array. Differentially altered circRNAs were validated by quantitative real-time polymerase chain reaction (qRT-PCR) in the 66 CSF samples of 33...

journal_title：BioMed research international

authors： Niu J,Xu H,Yang B

更新日期：2020-05-02 00:00:00

abstract：:Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

journal_title：BioMed research international

authors： He P,Hagiwara K,Chong H,Yu HH,Ito Y

更新日期：2015-01-01 00:00:00

abstract：Objective:Primary headache and obesity are highly prevalent disorders in the general population. Although many studies have reported an association between the two, there is still no overall comprehension about this relationship. To gain a more accurate understanding in this regard, we analyzed data from a 2011 cross-s...

journal_title：BioMed research international

authors： Huang Q,Yu H,Zhang N,Guo B,Feng C,Wang S,Liang X

更新日期：2019-04-15 00:00:00

abstract：:Exposure to dioxins, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is reported to affect the autoimmune system and increase the risk of autoimmune disease. Generally, dioxin exerts its toxicity via aryl hydrocarbon receptor (AhR). Primary biliary cholangitis (PBC) is a chronic autoimmune disease, and its pathoge...

journal_title：BioMed research international

authors： She C,Wang J,Tang N,Liu Z,Xu L,Liu B

更新日期：2020-08-24 00:00:00

abstract：Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smo...

journal_title：BioMed research international

authors： Miao JL,Cai JJ,Qin XF,Liu RJ

更新日期：2018-02-14 00:00:00

abstract：:CD13 is a membrane glycoprotein with aminopeptidase activity, expressed on several cell types, including myeloid cells (dendritic cells, monocytes, macrophages, neutrophils, etc.). CD13 participates in several functions such as proteolytic regulation of bioactive peptides, viral receptor, angiogenesis, and tumor metas...

journal_title：BioMed research international

authors： Garay-Canales CA,Licona-Limón I,Ortega E

更新日期：2018-03-29 00:00:00

abstract：:Recent studies suggest that nucleotide-binding domain leucine-rich repeat protein 1 (NLRP1) is a pivotal factor in the inflammatory process. However, the role of NLRP1 in breast cancer pathogenesis remains unclear. The aim of this study was to examine the expression and function of NLRP1 in breast cancer. We found tha...

journal_title：BioMed research international

authors： Wei Y,Huang H,Qiu Z,Li H,Tan J,Ren G,Wang X

更新日期：2017-01-01 00:00:00

abstract：:Hilar cholangiocarcinoma (HCC) remains one of the most difficult tumors to stage and treat. The aim of the study was to assess the diagnostic efficiency of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computer tomography (PET/CT) in evaluating the resectability of HCC. A...

journal_title：BioMed research international

authors： Zhang H,Zhu J,Ke F,Weng M,Wu X,Li M,Quan Z,Liu Y,Zhang Y,Gong W

更新日期：2015-01-01 00:00:00

abstract：:After decades of intensive searching for antimicrobial compounds derived from actinobacteria, the frequency of isolation of new molecules has decreased. To cope with this concern, studies have focused on the exploitation of actinobacteria from unexplored environments and actinobacteria symbionts of plants and animals....

journal_title：BioMed research international

authors： Mendes TD,Borges WS,Rodrigues A,Solomon SE,Vieira PC,Duarte MC,Pagnocca FC

更新日期：2013-01-01 00:00:00

abstract：:Freshly ejaculated spermatozoa are incapable or poorly capable of fertilizing an oocyte. The fertilization aptness of spermatozoa depends on the appropriate and time-dependent acquisition of hyperactivation, chemotaxis, capacitation, and the acrosome reaction, where calcium (Ca(2+)) is extensively involved in almost e...

journal_title：BioMed research international

authors： Rahman MS,Kwon WS,Pang MG

更新日期：2014-01-01 00:00:00

abstract：:Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic meth...

journal_title：BioMed research international

authors： Wu W,Wu S,Zhou Z,Zhang R,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:Introduction. The aim of the present study was to determine the closeness of agreement between a self-reported and an objective measure of physical activity in low back pain patients and healthy controls. Beyond, influencing factors on overestimation were identified. Methods. 27 low back pain patients and 53 healthy c...

journal_title：BioMed research international

authors： Schaller A,Rudolf K,Dejonghe L,Grieben C,Froboese I

更新日期：2016-01-01 00:00:00

abstract：:Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

journal_title：BioMed research international

authors： Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

更新日期：2020-08-26 00:00:00

abstract：:Endometrial carcinoma is the most common gynecological tumor worldwide. It can be the presenting malignancy, acting as the harbinger, of an undiagnosed hereditary syndrome. Up to 50% of females with Lynch syndrome present in this manner. Differentiation between Lynch, Muir-Torre, and Cowden syndromes can at times be c...

journal_title：BioMed research international

authors： Wong A,Ngeow J

更新日期：2015-01-01 00:00:00

abstract：:The spectrum of kidney disease-associated monoclonal immunoglobulin and plasma cell malignancies is remarkably broad and encompasses nearly all nephropathologic entities. Multiple myeloma with kidney impairment at presentation is a medical emergency since the recovery of kidney function is associated with survival ben...

journal_title：BioMed research international

authors： Mussap M,Merlini G

更新日期：2014-01-01 00:00:00