Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas.

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：:The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...

journal_title：BioMed research international

authors： Zhang H,Shen Y,Zhang Y,Li L,Wang X

更新日期：2018-01-29 00:00:00

abstract：:One of the female causes of infertility is anovulation which is treatable with gonadotropin hormones. These hormones affect the molecular organization of the uterus such as glycoconjugates that are the first site of contact between the blastocyst and the uterus. The objective of this project was to study the alteratio...

journal_title：BioMed research international

authors： Aliabadi E,Makoolati Z,Talaei-Khozani T,Ardekani FM,Aliabadi A

更新日期：2020-12-04 00:00:00

abstract：OBJECTIVE:There is a paucity of a biological large animal model of myocardial infarction (MI). We hypothesized that, using autologous-aggregated platelets, we could create an ovine model that was reproducible and more closely mimicked the pathophysiology of MI. METHODS:Mepacrine stained autologous platelets from male ...

journal_title：BioMed research international

authors： Spata T,Bobek D,Whitson BA,Parthasarathy S,Mohler PJ,Higgins RS,Kilic A

更新日期：2013-01-01 00:00:00

abstract：Background and Aim:ROHHADNET (rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, neuroendocrine tumor) syndrome is a rare disease with grave outcome. Although early recognition is essential, prompt diagnosis may be challenging due to its extreme rarity. This study aimed to systematically r...

journal_title：BioMed research international

authors： Lee JM,Shin J,Kim S,Gee HY,Lee JS,Cha DH,Rim JH,Park SJ,Kim JH,Uçar A,Kronbichler A,Lee KH,Shin JI

更新日期：2018-11-21 00:00:00

abstract：:Tomatoes and tomato based-foods contain beneficial microorganisms and various organic acids that have important nutritional values for human. The objective of this study was to access the physiochemical properties of fermented tomatoes juices and to evaluate the competitiveness of lactic acid bacteria (LAB) against Li...

journal_title：BioMed research international

authors： Bah A,Albano H,Barbosa JB,Fhoula I,Gharbi Y,Najjari A,Boudabous A,Teixeira P,Ouzari HI

更新日期：2019-02-26 00:00:00

abstract：:To explore the mechanisms by which andrographolide inhibits gastric cancer cell proliferation and metastasis, we employed the gastric cell line SGC7901 to investigate the anticancer effects of andrographolide. The cell survival ratio, cell migration and invasion, cell cycle, apoptosis, and matrix metalloproteinase act...

journal_title：BioMed research international

authors： Dai L,Wang G,Pan W

更新日期：2017-01-01 00:00:00

abstract：:Extra-intestinal E. coli are emerging as a global threat due to their diffusion as opportunistic pathogens and, above all, to their wide set of antibiotic resistance determinants. There are still many gaps in our knowledge of their origin and spread pathways, although food animals have been adjudicated vehicles for pa...

journal_title：BioMed research international

authors： Caruso G,Giammanco A,Cardamone C,Oliveri G,Mascarella C,Capra G,Fasciana T

更新日期：2018-11-18 00:00:00

abstract：:Interactions between proteins and drugs, which can lead to formation of stable drug-protein complexes, have important implications on several processes related to human health. These interactions can affect, for instance, free concentration, biological activity, and metabolism of the drugs in the blood stream. Here, w...

journal_title：BioMed research international

authors： Gorza FD,Pedro GC,Trescher TF,da Silva RJ,Silva JR,de Souza NC

更新日期：2014-01-01 00:00:00

abstract：:VEGF-NO axis uncoupling is an important pathogenesis for DN. Reduced β2GPI could play a part in VEGF signaling pathway and has a protective effect on diabetic vascular disease. This study investigates the effect of reduced β2GPI on glomerular mesangial cells VEGF-NO axis uncoupling induced by high glucose. Compared to...

journal_title：BioMed research international

authors： Saijun Z,Xin L,Jie W,Shumin X,Shuaihui L,Pei Y

更新日期：2018-07-18 00:00:00

abstract：:Freshly ejaculated spermatozoa are incapable or poorly capable of fertilizing an oocyte. The fertilization aptness of spermatozoa depends on the appropriate and time-dependent acquisition of hyperactivation, chemotaxis, capacitation, and the acrosome reaction, where calcium (Ca(2+)) is extensively involved in almost e...

journal_title：BioMed research international

authors： Rahman MS,Kwon WS,Pang MG

更新日期：2014-01-01 00:00:00

abstract：:This study is to investigate multiple chemotherapeutic agent- and radiation-related genetic biomarkers in locally advanced rectal cancer (LARC) patients following fluoropyrimidine-based concurrent chemoradiotherapy (CCRT) for response prediction. We initially selected 6 fluoropyrimidine metabolism-related genes (DPYD,...

journal_title：BioMed research international

authors： Huang MY,Wu CH,Huang CM,Chung FY,Huang CW,Tsai HL,Chen CF,Lin SR,Wang JY

更新日期：2013-01-01 00:00:00

abstract：:Black stain is characterized as a dark line or an incomplete coalescence of dark dots localized on the cervical third of the tooth. Over the last century, the etiology of black stain has been the subject of much debate. Most of the studies concerning this issue were conducted in pediatric population. According to the ...

journal_title：BioMed research international

authors： Żyła T,Kawala B,Antoszewska-Smith J,Kawala M

更新日期：2015-01-01 00:00:00

abstract：:Family planning coverage has improved in Ethiopia in the last decade, though fertility is still about 5.8 in the rural setup. In this paper, the major structural determinants of family planning service were analyzed using a multilevel model from 8906 individual women observation in the 2011 EDHS data. The results show...

journal_title：BioMed research international

authors： Gizachew Balew J,Cho Y,Tammy Kim C,Ko W

更新日期：2015-01-01 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：:Tumors and wounds share many similarities including loss of tissue architecture, cell polarity and cell differentiation, aberrant extracellular matrix (ECM) remodeling (Ballard et al., 2006) increased inflammation, angiogenesis, and elevated cell migration and proliferation. Whereas these changes are transient in repa...

journal_title：BioMed research international

authors： Tolg C,McCarthy JB,Yazdani A,Turley EA

更新日期：2014-01-01 00:00:00

abstract：:Tongue diagnosis is a noninvasive diagnosis and is traditionally one of the most important tools for physicians who practice Kampo (traditional Japanese) medicine. However, it is a subjective process, and its results can depend on the experience of the physician performing it. Previous studies have reported how to mea...

journal_title：BioMed research international

authors： Nakaguchi T,Takeda K,Ishikawa Y,Oji T,Yamamoto S,Tsumura N,Ueda K,Nagamine K,Namiki T,Miyake Y

更新日期：2015-01-01 00:00:00

abstract：:The Janus Kinases (JAKs) are a family of intracellular tyrosine kinases that provide transmission signals from cytokine, interferons, and many hormones receptors to the nucleus resulting in synthesis of many biologically active compounds and changing cell metabolism and function. That was theoretical background to syn...

journal_title：BioMed research international

authors： Kotyla PJ

更新日期：2018-05-10 00:00:00

abstract：:A diffusion theory-based, all-physical ab initio protein folding simulation is described and applied. The model is based upon the drift and diffusion of protein substructures relative to one another in the multiple energy fields present. Without templates or statistical inputs, the simulations were run at physiologic ...

journal_title：BioMed research international

authors： Kang Y,Fortmann CM

更新日期：2013-01-01 00:00:00

abstract：Introduction:The incidence of acute kidney injury (AKI) considerably increases the mortality rate in polytrauma victims. Undoubtedly, early identification of patients at risk is crucial for timely implementation of preventive strategies in order to improve their prognosis. Therefore, we aimed to investigate if serum ne...

journal_title：BioMed research international

authors： Negrin LL,Hahn R,Heinz T,Hajdu S

更新日期：2018-11-06 00:00:00

abstract：:There has been no previous study using three-dimensional (3D) measurement on femoral tunnel characteristics according to the combined influence of various flexion angles of knee and transverse drill angles in single-bundle ACL reconstruction with transportal technique. The purpose of this study was to determine optima...

journal_title：BioMed research international

authors： Kim SH,Kim SJ,Choi CH,Kim D,Jung M

更新日期：2018-07-17 00:00:00

abstract：:Craniofacial development consists of a highly complex sequence of the orchestrated growth and fusion of facial processes. It is also known that craniofacial abnormalities can be detected in 1/3 of all patients with congenital diseases. Within the various craniofacial abnormalities, orofacial clefting is one of the mos...

journal_title：BioMed research international

authors： Kurosaka H

更新日期：2015-01-01 00:00:00

abstract：:Purpose. This meta-analysis is to assess the effectiveness of teriparatide in fracture healing and clinical function improvement of the osteoporotic patients. Methods. We searched PubMed, Embase, Web of Science, and the Cochrane databases for randomized and quasi-randomized controlled trials comparing teriparatide to ...

journal_title：BioMed research international

authors： Lou S,Lv H,Wang G,Zhang L,Li M,Li Z,Zhang L,Tang P

更新日期：2016-01-01 00:00:00

abstract：:There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...

journal_title：BioMed research international

authors： Paldino E,Tesori V,Casalbore P,Gasbarrini A,Puglisi MA

更新日期：2014-01-01 00:00:00

abstract：:The proper methylation status of histones is essential for appropriate cell lineage and organogenesis. EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. The pig is an increasing important animal model for molecular study and pharmaceutical research. Ho...

journal_title：BioMed research international

authors： Tan B,Hong L,Qiao J,Zhou J,Xing P,Yan G,Zheng E,Cai G,Huang S,Wu Z,Gu T

更新日期：2020-10-05 00:00:00

abstract：:Several studies have compared molecular components between red and white skeletal muscles in mammals. However, mammalian skeletal muscles are composed of mixed types of muscle fibers. In the current study, we analyzed and compared the distributions of titin, lipid, phosphate ions, and fatty acid levels in red and whit...

journal_title：BioMed research international

authors： Wu MP,Chang NC,Chung CL,Chiu WC,Hsu CC,Chen HM,Sheu JR,Jayakumar T,Chou DS,Fong TH

更新日期：2018-11-18 00:00:00

abstract：INTRODUCTION:Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported in SAH, their origin remains unclear. The aim of this study was to report the detection of ES during routine TCD monitoring in patients with aneurysmal SAH. METHODS:...

journal_title：BioMed research international

authors： Paschoal FM Jr,de Almeida Lins Ronconi K,de Lima Oliveira M,Nogueira Rde C,Paschoal EH,Teixeira MJ,Figueiredo EG,Bor-Seng-Shu E

更新日期：2015-01-01 00:00:00

abstract：:Effect of Zataria multiflora on bacterial vaginosis and Trichomonas vaginalis is shown in vivo and in vitro. We compare the effectiveness of Zataria multiflora cream and oral metronidazole pill on results of treatment for vaginal infections including Trichomonas and bacterial vaginosis; these infections occur simultan...

journal_title：BioMed research international

authors： Abdali K,Jahed L,Amooee S,Zarshenas M,Tabatabaee H,Bekhradi R

更新日期：2015-01-01 00:00:00

abstract：:Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected. Objectives. The purpose of this study was to determine the magnitude of Leishmania sp. infection and potenti...

journal_title：BioMed research international

authors： Hoyos CL,Cajal SP,Juarez M,Marco JD,Alberti D'Amato AM,Cayo M,Torrejón I,Cimino RO,Diosque P,Krolewiecki AJ,Nasser JR,Gil JF

更新日期：2016-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00