Abstract：
:A major benefit of computational modeling in biomechanics research is its ability to estimate internal muscular demands given limited input information. However, several assumptions regarding model parameters and constraints may influence model outputs. This research evaluated the influence of model parameter variability, specifically muscle attachment locations and glenohumeral stability thresholds, on predicted rotator cuff muscle force during internal and external axial humeral rotation tasks. Additionally, relative sensitivity factors assessed which parameters were more contributory to output variability. Modest model parameter variation resulted in considerable variability in predicted force, with origin-insertion locations being particularly influential. Specifically, the scapula attachment site of the subscapularis muscle was important for modulating predicted force, with sensitivity factors ranging from α=0.2 to 0.7 in a neutral position. The largest variability in predicted forces was present for the subscapularis muscle, with average differences of 33.0±9.6% of normalized muscle force (1-99% CI), and a maximal difference of 51% in neutral exertions. Infraspinatus and supraspinatus muscles elicited maximal differences of 15.0 and 20.6%, respectively, between confidence limits. Overall, origin and insertion locations were most influential and thus incorporating geometric variation in the prediction of rotator cuff muscle forces may provide more representative population estimates.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Chopp-Hurley JN,Langenderfer JE,Dickerson CRdoi
10.1007/s10439-014-1035-3subject
Has Abstractpub_date
2014-09-01 00:00:00pages
1867-79issue
9eissn
0090-6964issn
1573-9686journal_volume
42pub_type
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journal_title：Annals of biomedical engineering
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pub_type： 杂志文章,评审
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pub_type： 临床试验,杂志文章
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更新日期：2014-01-01 00:00:00
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