Digital processing of the current noise evoked by kainate in cerebellar granule cells.

abstract：:A method of investigating head acceleration and intracranial dynamics from stick impacts in girls' and women's lacrosse was developed using headform impact experiments and a finite element head model. Assessing the likelihood of head injury due to stick-head impacts is of interest in girls' and women's lacrosse due to...

journal_title：Annals of biomedical engineering

authors： Morse JD,Franck JA,Wilcox BJ,Crisco JJ,Franck C

更新日期：2014-12-01 00:00:00

abstract：:Crowding can substantially affect the transition of a protein between its native (N) and unfolded (U) states via volume exclusion effects. Also, it influences considerably the aggregation (A) of unfolded proteins. To examine the details, we developed an approach for computing the kinetic rates of the process N <--> U ...

journal_title：Annals of biomedical engineering

authors： Despa F,Orgill DP,Lee RC

更新日期：2005-08-01 00:00:00

abstract：:The contractile power of the latissimus dorsi muscle (LDM) is used in skeletal muscle cardiac assist (SMCA) to augment the blood pumping ability of a failing heart. The LDM has three anatomically distinct, independently innervate segments-the transverse, oblique, and lateral. There are potential advantages to selectiv...

journal_title：Annals of biomedical engineering

authors： Thompson DR,Michele JJ,Cheever EA,George DT

更新日期：1999-01-01 00:00:00

abstract：:Magnetic (eddy-current) stimulation of the inspiratory motor nerves in the neck of the anesthetized dog was achieved. Using a 10-turn coil wound around the base of the neck and a train of pulses (25/s), inspiration was produced by tetanic contraction of the inspiratory muscles. The volume of air inspired increased wit...

journal_title：Annals of biomedical engineering

authors： Geddes LA,Mouchawar G,Bourland JD,ElAbbady T,Nyenhuis J

更新日期：1993-05-01 00:00:00

abstract：:Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue engineering by directing chondrocytes to synthesize/degrade the extracellular matrix or promote inflammatory responses. The aim of this paper was to investigate a...

journal_title：Annals of biomedical engineering

authors： Neidlin M,Korcari A,Macheras G,Alexopoulos LG

更新日期：2018-02-01 00:00:00

abstract：:A cohesive zone model (CZM) approach is applied to simulate atherosclerotic plaque delamination experiments in mouse abdominal aorta specimens. A three-dimensional finite element model is developed for the experiments. The aortic wall is treated as a fiber-reinforced, highly deformable, incompressible material, and th...

journal_title：Annals of biomedical engineering

authors： Leng X,Chen X,Deng X,Sutton MA,Lessner SM

更新日期：2015-12-01 00:00:00

abstract：:Peripheral nerve injuries present challenges to regeneration. Currently, the gold standard for nerve repair is an autograft that results in another region of the body suffering nerve damage. Previously, bioactive borate glass (BBG) has been studied in clinical trials to treat patients with non-healing wounds, and we h...

journal_title：Annals of biomedical engineering

authors： Gupta B,Papke JB,Mohammadkhah A,Day DE,Harkins AB

更新日期：2016-12-01 00:00:00

abstract：:A limitation of current tissue engineering vascular graft technology is the provision of an expandable, autologous cell source. By harnessing the multipotency of mesenchymal stem cells (MSC), it is hoped that functional vascular cells can be produced. To date, a range of 2D and 3D environments have been investigated f...

journal_title：Annals of biomedical engineering

authors： O'Cearbhaill ED,Murphy M,Barry F,McHugh PE,Barron V

更新日期：2010-03-01 00:00:00

abstract：:There is a significant clinical need for engineered bone graft substitutes that can quickly, effectively, and safely repair large segmental bone defects. One emerging field of interest involves the growth of engineered bone tissue in vitro within bioreactors, the most promising of which are perfusion bioreactors. Usin...

journal_title：Annals of biomedical engineering

authors： Ball O,Nguyen BB,Placone JK,Fisher JP

更新日期：2016-12-01 00:00:00

abstract：:The continuing lack of longitudinal histopathological and biomechanical data for human arteries in health and disease highlights the importance of studying the many genetic, pharmacological, and surgical models that are available in mice. As a result, there has been a significant increase in the number of reports on t...

journal_title：Annals of biomedical engineering

authors： Bersi MR,Ferruzzi J,Eberth JF,Gleason RL Jr,Humphrey JD

更新日期：2014-06-01 00:00:00

abstract：:Dendritic cell (DC) migration is required for efficient presentation of antigen to T cells and the initiation of an adaptive immune response. In spite of its importance, many aspects of DC migration have not been characterized. DCs encounter a variety of environments with different stiffness and geometry, but the effe...

journal_title：Annals of biomedical engineering

authors： Bendell AC,Anderson N,Blumenthal D,Williamson EK,Chen CS,Burkhardt JK,Hammer DA

更新日期：2018-09-01 00:00:00

abstract：:For the esophageal contractile activity recorded during swallowing, a feature extraction scheme has been developed. It recognizes the time, duration, and amplitudes of local peaks for each peristaltic wave. The method is based on the Tauberian approximation for modeling waveforms as a sum of identically shaped pulses ...

journal_title：Annals of biomedical engineering

authors： Abou-Chadi FE,Ezzat FA,Gad-Elhak N,Sif el-Din AA

更新日期：1993-03-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:Dynamic occlusal loading during mastication is clinically relevant in the design and functional assessment of dental restorations and removable dentures, and in evaluating temporomandibular joint dysfunction. The aim of this study was to develop a modelling framework to evaluate subject-specific dynamic occlusal loadi...

journal_title：Annals of biomedical engineering

authors： Woodford SC,Robinson DL,Edelmann C,Mehl A,Röhrle O,Vee Sin Lee P,Ackland DC

更新日期：2021-01-06 00:00:00

abstract：:Abdominal aortic aneurysms occur in as much as 2-3% of the population, and their rupture produces a mortality rate of 78-94% (1), causing 15,000 deaths per year in the U.S. alone. As an investigation into the mechanical factors that lead to aneurysm rupture, flow field measurements are presented for steady flow throug...

journal_title：Annals of biomedical engineering

authors： Asbury CL,Ruberti JW,Bluth EI,Peattie RA

更新日期：1995-01-01 00:00:00

abstract：:The field of tissue engineering promises to deliver biological substitutes to repair or replace tissues in the body that have been injured or diseased. The clinical demand for musculoskeletal tissues is particularly high, especially for cartilage and bone defects. Although they are generally considered biologically si...

journal_title：Annals of biomedical engineering

authors： Sharma B,Elisseeff JH

更新日期：2004-01-01 00:00:00

abstract：:Microstructural characterization of cardiac tissue and its remodeling in disease is a crucial step in many basic research projects. We present a comprehensive approach for three-dimensional characterization of cardiac tissue at the submicrometer scale. We developed a compression-free mounting method as well as labelin...

journal_title：Annals of biomedical engineering

authors： Seidel T,Edelmann JC,Sachse FB

更新日期：2016-05-01 00:00:00

abstract：:Abnormal scapular movement is widely believed to be an important factor in clinical pathology of the shoulder joint complex. Validated non-invasive techniques for measuring scapular movement have been developed, but the effect of marker placement on accuracy is unknown. The objective of this study was to determine the...

journal_title：Annals of biomedical engineering

authors： Bourne DA,Choo AM,Regan WD,MacIntyre DL,Oxland TR

更新日期：2011-02-01 00:00:00

abstract：:Microfluidic devices aim at miniaturizing, automating, and lowering the cost of chemical and biological sample manipulation and detection, hence creating new opportunities for lab-on-a-chip platforms. Recently, optofluidic devices have also emerged where optics is used to enhance the functionality and the performance ...

journal_title：Annals of biomedical engineering

authors： Bishara W,Isikman SO,Ozcan A

更新日期：2012-02-01 00:00:00

abstract：:Rapid screening of biomarkers, with high specificity and accuracy, is critical for many point-of-care diagnostics. Microfluidics, the use of microscale channels to manipulate small liquid samples and carry reactions in parallel, offers tremendous opportunities to address fundamental questions in biology and provide a ...

journal_title：Annals of biomedical engineering

authors： Ng E,Chen K,Hang A,Syed A,Zhang JX

更新日期：2016-04-01 00:00:00

abstract：:Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical pr...

journal_title：Annals of biomedical engineering

authors： Adams F,Qiu T,Mark A,Fritz B,Kramer L,Schlager D,Wetterauer U,Miernik A,Fischer P

更新日期：2017-04-01 00:00:00

abstract：:The field of percutaneous coronary intervention has witnessed many progressions over the last few decades, more recently with the advancement of fully degradable bioabsorbable stents. Bioabsorbable materials, such as metallic alloys and aliphatic polyesters, have the potential to yield stents which provide temporary s...

journal_title：Annals of biomedical engineering

authors： Boland EL,Shine R,Kelly N,Sweeney CA,McHugh PE

更新日期：2016-02-01 00:00:00

abstract：:This study proposes magnetic resonance (MR)-measurement-integrated (MR-MI) simulation, in which the difference between the computed velocity field and the phase-contrast MRI measurement data is fed back to the numerical simulation. The computational accuracy and the fundamental characteristics, such as steady characte...

journal_title：Annals of biomedical engineering

authors： Funamoto K,Suzuki Y,Hayase T,Kosugi T,Isoda H

更新日期：2009-06-01 00:00:00

abstract：:To study the effects of compressive straining on muscle cell deformation and damage an in vitro model system was developed. Myoblasts were seeded in agarose constructs and cultured in growth medium for 4 days. Subsequently, the cells were allowed to fuse into multinucleated myotubes for 8 days in differentiation mediu...

journal_title：Annals of biomedical engineering

authors： Bouten CV,Knight MM,Lee DA,Bade DL

更新日期：2001-02-01 00:00:00

abstract：:The nose is the front line defender of the respiratory system. Unsteady simulations in three-dimensional models have been developed to study transport patterns in the human nose and its overall air-conditioning capacity. The results suggested that the healthy nose can efficiently provide about 90% of the heat and the ...

journal_title：Annals of biomedical engineering

authors： Naftali S,Rosenfeld M,Wolf M,Elad D

更新日期：2005-04-01 00:00:00

abstract：:This article presents an overview of time-resolved (lifetime) fluorescence techniques used in biomedical diagnostics. In particular, we review the development of time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) instrumentation and associated methodologies which allow in vivo char...

journal_title：Annals of biomedical engineering

authors： Marcu L

更新日期：2012-02-01 00:00:00

abstract：:This paper describes a finite volume method for modeling electrical activation in a sample of cardiac tissue using the bidomain equations. Microstructural features to the level of cleavage planes between sheets of myocardial fibers in the tissue are explicitly represented. The key features of this implementation compa...

journal_title：Annals of biomedical engineering

authors： Trew M,Le Grice I,Smaill B,Pullan A

更新日期：2005-05-01 00:00:00

abstract：:The efforts to develop structural materials for biodegradable metal implants have lately shifted their focus from Magnesium and Iron base alloys towards Zinc. This was mainly due to the accelerated corrosion rate of Mg that is accompanied by hydrogen gas evolution, formation of voluminous iron oxide products with redu...

journal_title：Annals of biomedical engineering

authors： Kafri A,Ovadia S,Yosafovich-Doitch G,Aghion E

更新日期：2019-06-01 00:00:00

abstract：:The identification of the input to, or kernels of, a system using nonparametric representations and least-squares estimation is becoming increasingly popular. Nonparametric representations avoid making a priori assumptions about the input or having detailed knowledge about the system, and only need to guarantee known ...

journal_title：Annals of biomedical engineering

authors： Verotta D

更新日期：1998-09-01 00:00:00

abstract：:Polymeric heart valves have the potential to reduce thrombogenic complications associated with current mechanical valves and overcome fatigue-related problems experienced by bioprosthetic valves. In this paper we characterize the in vitro velocity and Reynolds Shear Stress (RSS) fields inside and downstream of three d...

journal_title：Annals of biomedical engineering

authors： Leo HL,Dasi LP,Carberry J,Simon HA,Yoganathan AP

更新日期：2006-06-01 00:00:00