Abstract:
:Thin spun-coat films (~4 nm thick) of graphene oxide (GO) constitute a versatile surface chemistry compatible with a broad range of technologically important sensor materials. Countless publications are dedicated to the nuances of surface chemistries that have been developed for sensors, with almost every material having unique characteristics. There would be enormous value in a surface chemistry that could be applied generally with functionalization and passivation already optimized regardless of the sensor material it covered. Such a film would need to be thin, conformal, and allow for multiple routes toward covalent linkages. It is also vital that the film permit the underlying sensor to transduce. Here we show that GO films can be applied over a diverse set of sensor surfaces, can link biomolecules through multiple reaction pathways, and can support cell growth. Application of a graphene veil atop a magnetic sensor array is demonstrated with an immunoassay. We also present biosensing and material characterization data for these graphene veils.
journal_name
Biotechniquesjournal_title
BioTechniquesauthors
Mulvaney SP,Stine R,Long NC,Tamanaha CR,Sheehan PEdoi
10.2144/000114188subject
Has Abstractpub_date
2014-07-01 00:00:00pages
21-30issue
1eissn
0736-6205issn
1940-9818pii
000114188journal_volume
57pub_type
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