Nutritional copper deficiency in severely handicapped patients on a low copper enteral diet for a prolonged period: estimation of the required dose of dietary copper.

Abstract:

:Six cases of nutritional copper deficiency were identified in a nursery institute for severely handicapped patients. All had been on prolonged enteral feeding of a copper-deficient diet and all had abnormalities related to the copper deficiency. Two of them had leukopenia, with or without macrocytic and normochromic anemia. After the oral administration of copper, the clinical and laboratory observations including neutrophil counts and serum copper and ceruloplasmin levels showed a complete recovery. The dietary copper requirement was estimated to be approximately 20 micrograms/kg/day for these patients, based on the correlation between the dietary copper intake and the levels of copper in the serum.

authors

Higuchi S,Higashi A,Nakamura T,Matsuda I

doi

10.1097/00005176-198807000-00018

subject

Has Abstract

pub_date

1988-07-01 00:00:00

pages

583-7

issue

4

eissn

0277-2116

issn

1536-4801

journal_volume

7

pub_type

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