SnRNP core protein enrichment in the nuclear matrix.

abstract：:Peptide array consisting of hundreds of peptides spatially addressed and synthesized on a cellulose membrane support was used to screen ligand-inhibitory peptides. As a model, angiotensin II (Ang II), a significant peptide related to the treatment of cardiovascular diseases, was chosen as the target ligand. Peptide ar...

journal_title：Biochemical and biophysical research communications

authors： Kato R,Kunimatsu M,Fujimoto S,Kobayashi T,Honda H

更新日期：2004-02-27 00:00:00

abstract：:Previous studies reported increased expression and activity of neutrophil elastase (NE) in NASH. However, the role of NE in nonalcoholic steatohepatitis (NASH) remained unclear. Wild type (WT) and NE knockout (NE KO) mice were fed with western diet (WD) for 24 weeks to establish NASH model. The severity of liver injur...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Liang B,Bian D,Luo Y,Yang J,Li Z,Zhuang Z,Zang S,Shi J

更新日期：2019-10-22 00:00:00

abstract：:The poly(rC)-binding protein PCBP2 has multiple functions in post-transcriptional control of host and viral gene expression. Since it interacts with picornaviral RNA structures, it was proposed that PCBP2 regulates viral genome translation and replication. The hepatitis A virus (HAV), an atypical picornavirus, contain...

journal_title：Biochemical and biophysical research communications

authors： Zhang B,Seitz S,Kusov Y,Zell R,Gauss-Müller V

更新日期：2007-12-28 00:00:00

abstract：:Glucose transporter-1 (GLUT1) is important in placental glucose transport. However, the mechanism of regulation of placental GLUT1 expression remains to be elucidated. We show here that the level of GLUT1 protein in rat choriocarcinoma cells (Rcho-1) decreased during differentiation. To analyze the regulatory mechanis...

journal_title：Biochemical and biophysical research communications

authors： Okamoto Y,Sakata M,Yamamoto T,Nishio Y,Adachi K,Ogura K,Yamaguchi M,Takeda T,Tasaka K,Murata Y

更新日期：2001-11-09 00:00:00

abstract：:A variant of annexin 3 (AX3) of apparent mass 36 kD has been detected in human monocytes using a specific immune serum directed against the original 33-kD form of AX3 purified from human placenta. This protein is not a phosphorylated or a glycosylated form of the 33-kD AX3 and its expression increased along monocytic ...

journal_title：Biochemical and biophysical research communications

authors： Le Cabec V,Russo-Marie F,Maridonneau-Parini I

更新日期：1992-12-30 00:00:00

abstract：:Acinetobacter lwoffii K24 known as an aniline degrading bacterium has also been found to utilize p-hydroxybenzoate as a sole carbon source. In this study, 2-DE using Q-Sepharose column separation was attempted for fast screening of protocatechuate 3,4-dioxygenase for catabolism of p-hydroxybenzoate in A. lwoffii K24. ...

journal_title：Biochemical and biophysical research communications

authors： Kahng HY,Cho K,Song SY,Kim SJ,Leem SH,Kim SI

更新日期：2002-07-26 00:00:00

abstract：:Previous studies have shown that DNA strand breaks are an early consequence of nitric oxide toxicity in pancreatic islet cells. We show here that exposure of islet cells to chemical NO donors causes the formation of ADP-ribose polymers in cell nuclei, with concomitant depletion of intracellular NAD+. Islet cell lysis ...

journal_title：Biochemical and biophysical research communications

authors： Radons J,Heller B,Bürkle A,Hartmann B,Rodriguez ML,Kröncke KD,Burkart V,Kolb H

更新日期：1994-03-30 00:00:00

abstract：:Specific polyclonal antibodies raised against purified human platelet Ca2+-ATPase were used with protein A-gold immunocytochemistry to localize this protein in human platelets. Immunolabeling specifically detected Ca2+-ATPase over the surface connected membrane system (SCS) in sections of paraformaldehyde-fixed, Lowic...

journal_title：Biochemical and biophysical research communications

authors： Herbener GH,Dean WL

更新日期：1988-06-16 00:00:00

abstract：:We designed an experimental approach to differentiate the kinetics of protein binding to a lipid membrane from the kinetics of the associated conformational change in the protein. We measured the fluorescence intensity of the single Trp6 in chicken liver bile acid-binding protein (L-BABP) as a function of time after m...

journal_title：Biochemical and biophysical research communications

authors： Galassi V,Nolan V,Villarreal MA,Perduca M,Monaco HL,Montich GG

更新日期：2009-05-15 00:00:00

abstract：:Low voltage-activated, rapidly inactivating T-type Ca(2+) channels are found in a variety of cells where they regulate electrical activity and Ca(2+) entry. In whole-cell patch clamp recordings from bovine adrenal zona fasciculata cells, cis-polyunsaturated omega-3 fatty acids including docosahexaenoic acid (DHA), eic...

journal_title：Biochemical and biophysical research communications

authors： Danthi SJ,Enyeart JA,Enyeart JJ

更新日期：2005-02-11 00:00:00

abstract：:Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that is known to reduce hepatic low-density lipoprotein receptor (LDLR) levels and increase plasma LDL cholesterol. It is not clear, however, whether secreted PCSK9 degrades extrahepatic LDLRs. We present evidence that recombinant PCSK9, either...

journal_title：Biochemical and biophysical research communications

authors： Schmidt RJ,Beyer TP,Bensch WR,Qian YW,Lin A,Kowala M,Alborn WE,Konrad RJ,Cao G

更新日期：2008-06-13 00:00:00

abstract：:The yellow locus in Drosophila is involved in both cuticle development and behaviour. However, the function of the encoded protein is unknown. Here we have characterised the sequence and expression pattern of a new Drosophila gene, designated yellow-B, encoding a 453-amino-acid protein that is 57% identical to Yellow....

journal_title：Biochemical and biophysical research communications

authors： Maleszka R,Kucharski R

更新日期：2000-04-21 00:00:00

abstract：:Treatment of the cells of the 311 cell line, a pluripotent mouse teratocarcinoma cell line, with 12-O-tetradecanoylphorbol-13-acetate (TPA) modulates c-mos expression. Transient suppression of 6.1 and 4.6 kilobases (kb) transcripts and activation of 1.8 transcript indicate that TPA mediates concurrently positive and n...

journal_title：Biochemical and biophysical research communications

authors： Ogiso Y,Kitagawa K,Nishino H,Iwashima A

更新日期：1988-07-15 00:00:00

abstract：:The NC1 domains from the different α(IV) collagen chains were found to exert anti-tumorigenic and/or anti-angiogenic activities. A limitation to the therapeutic use of these matrikines is the large amount of purified recombinant proteins, in the milligram range in mice that should be administered daily throughout the ...

journal_title：Biochemical and biophysical research communications

authors： Thevenard J,Ramont L,Mir LM,Dupont-Deshorgue A,Maquart FX,Monboisse JC,Brassart-Pasco S

更新日期：2013-03-22 00:00:00

abstract：:The effects of cAMP on the expression of ETA (ET-1 selective type) receptor mRNA and on the response to endothelin-1 (ET-1) were investigated in rat aortic smooth muscle cells in primary culture, using reverse transcription polymerase chain reaction (RT-PCR) and fura-2 microfluorometry of cytosolic Ca2+ concentrations...

journal_title：Biochemical and biophysical research communications

authors： Nishimura J,Chen X,Jahan H,Shikasho T,Kobayashi S,Kanaide H

更新日期：1992-10-30 00:00:00

abstract：:Cancer stem cells (CSCs) play essential role in the progression of many tumors. Wnt/β-catenin pathway is crucial in maintaining the stemness of CSCs. (-)-Epigallocatechin-3-gallate (EGCG), the major bioactive component in green tea, has been shown to possess anti-cancer activity. To date, the interventional effect of ...

journal_title：Biochemical and biophysical research communications

authors： Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C

更新日期：2017-01-01 00:00:00

abstract：:A soluble factor, extracted from neutrophils and P388D1 cells, stimulated a transient rise in cytosolic free Ca2+ and a small increase in the permeability to Mn2+ in fura2-loaded neutrophils. These effects were not prevented by blockade of formylated peptide receptors by t-boc-met-leu-phe. The rise in cytosolic free C...

journal_title：Biochemical and biophysical research communications

authors： Davies EV,Hallett MB

更新日期：1995-01-05 00:00:00

abstract：:This study defines the total sodium-23 magnetic resonance spectroscopy (23Na MRS) signal from in vivo heterotopic rat heart transplants in the early post-transplant period and examines the utility of this noninvasive method for monitoring allograft rejection. Measurements were performed at 4.7 T. Syngeneic (n = 6) and...

journal_title：Biochemical and biophysical research communications

authors： Waldrop SM,Alexander DZ,Lowry R,Winn KJ,Pearson TC,Constantinidis I

更新日期：1996-06-14 00:00:00

abstract：:Taxol (paclitaxel), a microtubule stabilizer with antitumor activity, mimics the actions of lipopolysaccharide (LPS) on murine macrophages (M phi). In the present study, a variety of synthetic analogs of paclitaxel were examined for their potencies to induce nitric oxide (NO) and tumor necrosis factor (TNF) production...

journal_title：Biochemical and biophysical research communications

authors： Kirikae T,Ojima I,Kirikae F,Ma Z,Kuduk SD,Slater JC,Takeuchi CS,Bounaud PY,Nakano M

更新日期：1996-10-03 00:00:00

abstract：:In order to isolate new subtypes of P2Y purinoceptors, a human placenta cDNA library was screened at middle stringency with a P2Y4 probe. The purification and the sequencing of several clones led us to identify a 984 base pair open reading frame encoding a new human P2Y receptor. It appeared later that this sequence c...

journal_title：Biochemical and biophysical research communications

authors： Communi D,Parmentier M,Boeynaems JM

更新日期：1996-05-15 00:00:00

abstract：:Complementation studies, using fused cell lines from patients with peroxisomal disorders, have shown correction of defective plasmalogen synthesis and phytanic acid oxidation as well as an increase in the number of peroxisomes. At least six complementation groups have been reported. We demonstrate here that complement...

journal_title：Biochemical and biophysical research communications

authors： McGuinness MC,Moser AB,Moser HW,Watkins PA

更新日期：1990-10-15 00:00:00

abstract：:Male Djungarian hamsters (Phodopus sungorus; 45 animals per group) were either sham-exposed or exposed to a sinusoidal magnetic field for 56 days (Experiment 1: 50 Hz, 450 microTesla peak; max. dB/dt = 140 mTesla s(-1); 24 hrs day(-1)). Except for day 7, no effects were observed with respect to body weights during exp...

journal_title：Biochemical and biophysical research communications

authors： Niehaus M,Brüggemeyer H,Behre HM,Lerchl A

更新日期：1997-05-29 00:00:00

abstract：:A cDNA for a type II antifreeze protein was isolated from liver of smelt (Osmerus mordax). The predicted protein sequence is homologous to that from sea raven (Hemitripterus americanus) and both show homology to a family of calcium-dependent lectins. Smelt and sea raven belong to taxonomic orders believed to have dive...

journal_title：Biochemical and biophysical research communications

authors： Ewart KV,Rubinsky B,Fletcher GL

更新日期：1992-05-29 00:00:00

abstract：:The new bacterial vector pETM60 enables the expression of His-tagged recombinant proteins fused to the C-terminus of NusA through a TEV protease recognition sequence. Three sequences coding for two protein domains (Xklp3A and Tep3Ag) and one membrane-bound viral protein (E8R) could not be expressed in a soluble form i...

journal_title：Biochemical and biophysical research communications

authors： De Marco V,Stier G,Blandin S,de Marco A

更新日期：2004-09-24 00:00:00

abstract：:Histone deacetylases (HDACs) are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. Deacetylation of epsilon-acetyl-lysine residues within the N-terminal tail of core histones mediates changes in both histone-DNA and histone-non-histone protein interactions. However, surprisin...

journal_title：Biochemical and biophysical research communications

authors： Riester D,Wegener D,Hildmann C,Schwienhorst A

更新日期：2004-11-19 00:00:00

abstract：:The pattern of micrococcal nuclease digestion of chromatin from different organs of Allium cepa has been studied. The DNA from small oligonucleosomes appears to be highly degraded and heterogeneous. In solutions of intermediate ionic strength (0.15 M NaCl) histones H2A and H2B form dimers, however at high salt concent...

journal_title：Biochemical and biophysical research communications

authors： Moreno ML,Puigdomenech P,Palau J

更新日期：1985-06-28 00:00:00

abstract：:Cerebral ischemia is accompanied by fulminant cellular and humoral inflammatory changes in the brain which contribute to lesion development after stroke. A tight interplay between the brain and the peripheral immune system leads to a biphasic immune response to stroke consisting of an early activation of peripheral im...

journal_title：Biochemical and biophysical research communications

authors： Czech B,Pfeilschifter W,Mazaheri-Omrani N,Strobel MA,Kahles T,Neumann-Haefelin T,Rami A,Huwiler A,Pfeilschifter J

更新日期：2009-11-13 00:00:00

abstract：:The incorporation of 32Pi into the 47 and 20 kDa polypeptides in platelets activated by wheat germ agglutinin (WGA) was studied. The pattern of enhanced phosphorylation produced by the lectin was comparable to that by thrombin. The 47 kDa polypeptide was phosphorylated at both serine and threonine while the 20 kDa pro...

journal_title：Biochemical and biophysical research communications

authors： Ganguly CL,Chelladurai M,Ganguly P

更新日期：1985-10-15 00:00:00

abstract：:Hand-foot skin reaction (HFSR) is a common side effect of multiple tyrosine kinase inhibitors (mTKIs). HFSR can necessitate dose reductions or interruption of therapy owing to its negative effect on the quality of life. Therefore, effective use of mTKIs requires measures to prevent HFSR. We evaluated the effect of pro...

journal_title：Biochemical and biophysical research communications

authors： Shichiri H,Yamamoto K,Tokura M,Ishida T,Uda A,Bito T,Nishigori C,Nakagawa T,Hirano T,Yano I,Hirai M

更新日期：2017-04-01 00:00:00

abstract：:The phenothiazine antipsychotic drug chlorpromazine, a potent calmodulin antagonist, inhibited human natural killer cell-mediated cytotoxicity in a dose-dependent manner. This inhibition of natural killer cell activity was not due to interference with conjugate formation, nor was it due to toxicity to the natural kill...

journal_title：Biochemical and biophysical research communications

authors： Steele TA,Brahmi Z

更新日期：1988-09-15 00:00:00