Growth retardation, testicular stimulation, and increased melatonin synthesis by weak magnetic fields (50 Hz) in Djungarian hamsters, Phodopus sungorus.

Abstract:

:Male Djungarian hamsters (Phodopus sungorus; 45 animals per group) were either sham-exposed or exposed to a sinusoidal magnetic field for 56 days (Experiment 1: 50 Hz, 450 microTesla peak; max. dB/dt = 140 mTesla s(-1); 24 hrs day(-1)). Except for day 7, no effects were observed with respect to body weights during exposure. However, testicular cell numbers were significantly increased by exposure (tetraploid (4C): p=0.022; diploid (2C): p=0.039). Rectangular magnetic fields (Experiment 2: 360 microTesla; max. dB/dt = 2.5 Tesla s(-1)) caused a significant (p<0.001) but transient suppressing effect on body weights. Significant increases were also observed in testicular cell numbers (4C: p=0.034; haploid (1C): p=0.014) and in serum melatonin (p=0.001). It is concluded that weak magnetic fields may affect reproductive and physiological functions in the mammalian species tested and that the degree of these effects depends upon the fields' gradients.

authors

Niehaus M,Brüggemeyer H,Behre HM,Lerchl A

doi

10.1006/bbrc.1997.6561

subject

Has Abstract

pub_date

1997-05-29 00:00:00

pages

707-11

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(97)96561-X

journal_volume

234

pub_type

杂志文章
  • Ser-261 phospho-regulation is involved in pS256 and pS269-mediated aquaporin-2 apical translocation.

    abstract::Vasopressin catalyzes aquaporin-2 phosphorylation at several serine sites in the C-terminal region. Compared with Ser-256 and Ser-269 phosphorylation, the role of Ser-261 phospho-regulation on vasopressin-regulated AQP2 apical translocation is largely unknown. In addition, recent discovery of transcytotic apical deliv...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2017.06.162

    authors: Yui N,Ando F,Sasaki S,Uchida S

    更新日期:2017-08-26 00:00:00

  • Purification and mutagenesis studies of TANC1 ankyrin repeats domain provide clues to understand mis-sense variants from diseases.

    abstract::TANC1 and its close relative TANC2 are two important synaptic scaffold proteins which play critical roles in regulating densities of synaptic spines and excitatory synapse strength. Recent studies indicated TANC1 and TANC2 are candidate genes of several neurodevelopmental disorders (NDD). So far, the biochemical prope...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2019.04.151

    authors: Yang Q,Liu H,Li Z,Wang Y,Liu W

    更新日期:2019-06-25 00:00:00

  • miR-199b-5p modulates BMSC osteogenesis via suppressing GSK-3β/β-catenin signaling pathway.

    abstract::miR-199b-5p is up-regulated significantly during the osteogenesis process in human bone marrow stromal cells (BMSCs). Inhibiting miR-199b-5p notably reduces while over-expressing miR-199b-5p promotes the BMSCs osteoblast differentiation, suggested by the alternations of osteogenic genes expression, ALP activity and th...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2016.06.130

    authors: Zhao R,Li Y,Lin Z,Wan J,Xu C,Zeng Y,Zhu Y

    更新日期:2016-09-02 00:00:00

  • Diverse gating in K+ channels: differential role of the pore-helix glutamate in stabilizing the channel pore.

    abstract::The selectivity filter and adjacent regions in the bacterial KcsA and inwardly rectifying K(+) (Kir) channels reveal significant conformational changes that cause the channel pore to transition from an activated to inactive state (C-type inactivation) once the channel is open. The meshwork of residues stabilizing the ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbrc.2011.08.062

    authors: Raja M

    更新日期:2011-09-16 00:00:00

  • HSP-1/2, a major protein of equine seminal plasma, exhibits chaperone-like activity.

    abstract::The major bovine seminal plasma protein, PDC-109 exhibits chaperone-like activity (CLA) against a variety of target proteins. The present studies show that the homologous protein from equine seminal plasma, HSP-1/2 also exhibits CLA and inhibits the thermal aggregation of target proteins such as lactate dehydrogenase,...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2012.08.120

    authors: Sankhala RS,Kumar CS,Singh BP,Arangasamy A,Swamy MJ

    更新日期:2012-10-12 00:00:00

  • Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation.

    abstract::The human immunodeficiency virus type 1 (HIV-1) Tat is a virally encoded protein that dramatically up-regulates viral replication through interactions with the HIV-1 5' long terminal repeat (LTR) and cellular transcription factors. The HIV-1 LTR is divided into three major regions: modulatory, core and TAR. The modula...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2001.5442

    authors: Li X,Josef J,Marasco WA

    更新日期:2001-08-24 00:00:00

  • Ferric nitrilotriacetate (Fe-NTA) is a potent hepatic tumor promoter and acts through the generation of oxidative stress.

    abstract::Fe-NTA is a known renal carcinogen. However, little is known about its carcinogenic potential in liver. In this study we for the first time show that Fe-NTA is a potent hepatic tumor promoter. Fe-NTA administration induced dose dependently the hepatic ornithine decarboxylase (ODC) activity several folds as compared to...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.2006

    authors: Iqbal M,Giri U,Athar M

    更新日期:1995-07-17 00:00:00

  • Mutation of the carboxy terminal zinc finger of E. coli isoleucyl-tRNA synthetase alters zinc binding and aminoacylation activity.

    abstract::Escherichia coli isoleucyl-tRNA synthetase has been shown to contain two enzyme-bound zinc atoms per polypeptide chain. To investigate the structural and functional significance of the C-terminal enzyme-bound zinc, mutagenesis was used to alter Cys 922 to Ser [IleRS(C922S)] and to replace Cys 922 through Ala 939 with ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.2671

    authors: Zhou L,Rosevear PR

    更新日期:1995-11-13 00:00:00

  • Characterization of the specific interaction between archaeal FHA domain-containing protein and the promoter of a flagellar-like gene-cluster and its regulation by phosphorylation.

    abstract::The mechanism and target genes of regulation by Forkhead (FHA) domain-containing transcription factors have not yet been documented in Archaea. In this study, using a bacterial one-hybrid technique, we successfully screened and identified for the first time a target gene regulated by ST0829, an FHA domain-containing p...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2011.03.011

    authors: Duan X,He ZG

    更新日期:2011-04-01 00:00:00

  • Ligand effects on the limited proteolysis of phenylalanine hydroxylase: evidence for multiple conformational states.

    abstract::The effects of phenylalanine and tetrahydrobiopterin on the limited proteolysis of rat liver phenylalanine hydroxylase by chymotrypsin have been examined. The presence of tetrahydrobiopterin inhibits the proteolytic activation of native phenylalanine hydroxylase. In contrast, phenylalanine causes a stimulation of prot...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(83)91050-1

    authors: Phillips RS,Iwaki M,Kaufman S

    更新日期:1983-02-10 00:00:00

  • β1-Adrenergic receptor downregulates the expression of cyclooxygenase-2.

    abstract::Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in the generation of prostanoids, and is thus one of the key players in the inflammatory process. Contrary to the constitutively expressed isoform COX-1, the expression of COX-2 is rapidly and transiently upregulated following pathological stimuli but little is...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2014.07.123

    authors: Brender S,Barki-Harrington L

    更新日期:2014-08-22 00:00:00

  • Comparison of the disulfide bond arrangements of human recombinant and bovine brain heparin binding neurite-promoting factors.

    abstract::Heparin binding neurite-promoting factor (HBNF) is a highly basic 136 amino acid protein containing 10 cysteine residues. We have determined the redox status and the disulfide arrangement of the cysteine residues in HBNF from bovine brain and refolded human recombinant protein produced in E. coli. Our data indicate th...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1993.1476

    authors: Hulmes JD,Seddon AP,Decker MM,Böhlen P

    更新日期:1993-04-30 00:00:00

  • Characterization of actin and tubulin promoters from two sap-sucking pests, Nilaparvata lugens (Stål) and Nephotettix cincticeps (Uhler).

    abstract::The brown planthopper, Nilaparvata lugens (N. lugens, Hemiptera: Delphacidae), and the green rice leafhopper, Nephotettix cincticeps (N. cincticeps, Hemiptera: Cicadellidae), two sap-sucking feeders, have caused many destructive agricultural disasters in East Asia, as they can bring diseases like 'hopper burn' and tra...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2016.01.124

    authors: Qian N,Zheng P,Wang Y,Pan S,Li Y,Zhang C,Chen J,Teng J

    更新日期:2016-02-19 00:00:00

  • Protein arginine methyltransferase 1 mediates regeneration in Dugesia japonica.

    abstract::As a typical organism of platyhelminth, Dugesia japonica attracts more and more attention for its strong regenerative ability. Protein arginine methyltransferase (PRMT) family is composed of a class of enzymes with methyltransferase activities, which play fundamental roles in vivo in many important physiological proce...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2020.01.087

    authors: Zhang Y,Wu W,Gao L,Chen M,Liu X,Huang M,Li A,Zheng K,Liu D,Deng H,Zhao B,Liu B,Pang Q

    更新日期:2020-04-02 00:00:00

  • Retinoic acid switches differential expression of FGF8 isoforms in LNCaP cells.

    abstract::Retinoic acid (RA) is described as an inhibitor of prostate cancer cell growth. We utilized reverse transcription-polymerase chain reaction (RT-PCR) to analyze expression of different isoforms of fibroblast growth factor 8 (FGF8) in response to RA. Results in the prostate cancer cell line LNCaP show that whereas overa...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2000.2740

    authors: Brondani V,Hamy F

    更新日期:2000-05-27 00:00:00

  • Differential roles of TIMP-4 and TIMP-2 in pro-MMP-2 activation by MT1-MMP.

    abstract::The tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of MMP enzymatic activity. However, TIMP-2 can promote the activation of pro-MMP-2 by MT1-MMP. This process is mediated by the formation of a complex between MT1-MMP, TIMP-2, and pro-MMP-2. Binding of TIMP-2 to active MT1-MMP also inhibits the...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2001.4323

    authors: Hernandez-Barrantes S,Shimura Y,Soloway PD,Sang QA,Fridman R

    更新日期:2001-02-16 00:00:00

  • Reduced secretion and expression of gelatinase profile in Toxoplasma gondii-infected human monocytic cells.

    abstract::The apicomplexan Toxoplasma gondii, an obligate intracellular parasite, can infect humans and a wide range of vertebrates. Following oral infection, the parasite invades tissues by crossing non-permissive biological barriers such as the placenta or the blood-brain barrier. But the molecular mechanisms underlying migra...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2007.05.089

    authors: Buache E,Garnotel R,Aubert D,Gillery P,Villena I

    更新日期:2007-07-27 00:00:00

  • Differences in stability of recombinant apoaequorin within subcellular compartments.

    abstract::Recombinant acquorin is widely used as an intracellular Ca2+ indicator within live cells. Our data shows that recombinant apoacquorin was unstable within the cytosol, with a half life of approximately 20 minutes. Targeting of the protein to subcellular organelles resulted in an increase in stability which may be due t...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.2862

    authors: Badminton MN,Sala-Newby GB,Kendall JM,Campbell AK

    更新日期:1995-12-26 00:00:00

  • A bispecific antibody (ScBsAbAgn-2/TSPO) target for Ang-2 and TSPO resulted in therapeutic effects against glioblastomas.

    abstract::Antibody-based targeted therapy of cancers requires the antibody targeting of specific molecules inducing tumor cells apoptosis or death. Angiopoietin-2 (Agn-2) and translocator protein (TSPO) are identified as potential target molecules for glioblastoma therapy. The single chain anti-Agn-2 antibody (Anag-2) and anti-...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2016.02.035

    authors: Li J,Zhang Z,Lv L,Qiao H,Chen X,Zou C

    更新日期:2016-04-01 00:00:00

  • Expression of PrP mRNA is regulated by a fragment of MRP8 in human fibroblasts.

    abstract::Prion protein (PrPc) is expressed in many tissues, both in human and animals. The scrapie isoform of PrPc has been shown to cause neurodegeneration. In other studies it has been demonstrated that overexpression of the PrP gene can result in nonneuronal tissue degradation. Little is known, however, about the normal fun...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1997.6575

    authors: Kniazeva M,Orman R,Terranova VP

    更新日期:1997-05-08 00:00:00

  • Hexose transport in plasma membrane vesicles prepared from L6 rat myoblasts.

    abstract::Hexose transport in plasma membrane vesicles prepared from L6 rat myoblasts was shown to be stereospecific, activated by glucose starvation and occurred by both high and low affinity systems. Transport by the high affinity system was shown to occur by an active transport process. Furthermore, the high affinity system ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/s0006-291x(86)80343-6

    authors: Mesmer O,Cheung MO,D'Amore T,Lo TC

    更新日期:1986-11-26 00:00:00

  • Alternative splicing model for the synthesis and secretion of the 20 kilodalton form of rat growth hormone.

    abstract::The characterization of a 20 kilodalton (20 kD) variant of rat growth hormone is reported. The 20 kD variant from rat pituitary gland extracts was identified on Western immunoblots of polyacrylamide gels. It was also shown that pituitary tissue maintained in culture secretes the 20 kD form. A rat growth hormone cDNA f...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(87)90980-6

    authors: Howland DS,Farrington MA,Taylor WD,Hymer WC

    更新日期:1987-09-15 00:00:00

  • The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling.

    abstract::Myocyte enhancer factor 2C (MEF2C) plays an important role in cardiovascular development and is a key transcription factor for cardiac hypertrophy. Here, we describe MEF2C regulation by insulin-like growth factor-1 (IGF-1) and its role in IGF-1-induced cardiac hypertrophy. We found that IGF-1 addition to cultured rat ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2009.07.147

    authors: Muñoz JP,Collao A,Chiong M,Maldonado C,Adasme T,Carrasco L,Ocaranza P,Bravo R,Gonzalez L,Díaz-Araya G,Hidalgo C,Lavandero S

    更新日期:2009-10-09 00:00:00

  • Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells.

    abstract::The aim of this study was to investigate the response to and the physiological consequences of copper-mediated cross-linking of S100A2 and S100A4, two members of the S100 family of EF-hand calcium-binding proteins. As demonstrated by electrophoresis and mass spectrometry techniques S100A2 and S100A4 show formation of ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2011.08.132

    authors: Haase-Kohn C,Wolf S,Lenk J,Pietzsch J

    更新日期:2011-09-30 00:00:00

  • Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonica.

    abstract::Sensitization to Cupressaceae pollen has become one of the most important causes of pollinosis in Western countries during winter and early spring. However, the characterization of the extracts, the allergens involved and the cross-reactivity with other pollen sources still remain poorly studied; in the case of Cupres...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2010.09.079

    authors: Pico de Coaña Y,Parody N,Fuertes MÁ,Carnés J,Roncarolo D,Ariano R,Sastre J,Mistrello G,Alonso C

    更新日期:2010-10-22 00:00:00

  • Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling.

    abstract::Toll-like receptor 4 (TLR4) activates two distinct signaling pathways inducing production of proinflammatory cytokines or type I interferons (IFNs), respectively. MyD88 and TIRAP/Mal are essential adaptor molecules for the former but not for the latter pathway. In contrast, TRIF/TICAM-1 and TRAM/TICAM-2 are essential ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2008.01.061

    authors: Tanimura N,Saitoh S,Matsumoto F,Akashi-Takamura S,Miyake K

    更新日期:2008-03-28 00:00:00

  • A CUGGU/UUGGU-specific MazF homologue from Methanohalobium evestigatum.

    abstract::MazF is a sequence-specific endoribonuclease or mRNA interferase, which cleaves RNA at a specific sequence. Since the expression of a specific gene or a group of specific genes can be regulated by MazF, expanding the repertoire of recognition sequences by MazF mRNA interferases is highly desirable for biotechnological...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2019.08.076

    authors: Ishida Y,Inouye K,Ming O,Inouye M

    更新日期:2019-10-20 00:00:00

  • Biological selectivity and functional aspects of protein tyrosine nitration.

    abstract::The formation of nitric oxide in biological systems has led to the discovery of a number of post-translational protein modifications that could regulate protein function or potentially be utilized as transducers of nitric oxide signaling. Principal among the nitric oxide-mediated protein modifications are: the nitric ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章,评审

    doi:10.1016/s0006-291x(03)00814-3

    authors: Ischiropoulos H

    更新日期:2003-06-06 00:00:00

  • Transfection of "naked" siRNA results in endosomal uptake and metabolic impairment in cultured neurons.

    abstract::RNA interference is rapidly becoming a powerful tool for gene silencing in mammalian cells. Introduction of siRNA into primary cells, however, remains one of the major difficulties of this novel technique. Using cationic lipid-based transfection reagents satisfactory transfection results are observed in cell lines, bu...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2004.01.170

    authors: Lingor P,Michel U,Schöll U,Bähr M,Kügler S

    更新日期:2004-03-19 00:00:00

  • Quantitative proteomics reveals key proteins regulated by eicosapentaenoic acid in endothelial activation.

    abstract::Eicosapentaenoic acid (EPA), an n-3 polyunsaturated fatty acid (PUFA), has been shown to decrease the risk of atherosclerosis by attenuating endothelial activation. In this study, we used mass spectrometry-based label-free quantitative proteomics to study the protective mechanisms of EPA and to identify key proteins t...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2017.04.091

    authors: Zhang L,Xiao K,Zhao X,Sun X,Zhang J,Wang X,Zhu Y,Zhang X

    更新日期:2017-05-27 00:00:00