当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Analysis of allogeneic and syngeneic rat heart transplants using 23Na magnetic resonance spectroscopy.

Analysis of allogeneic and syngeneic rat heart transplants using 23Na magnetic resonance spectroscopy.

Abstract：

:This study defines the total sodium-23 magnetic resonance spectroscopy (23Na MRS) signal from in vivo heterotopic rat heart transplants in the early post-transplant period and examines the utility of this noninvasive method for monitoring allograft rejection. Measurements were performed at 4.7 T. Syngeneic (n = 6) and allogeneic (n = 6) donor hearts were transplanted into the neck of recipient rats. There were 27 MRS observations between days 0 and 29 post-transplant. Heart grafts were excised at various intervals post-transplant for histologic examination. Allogeneic heart grafts rejected between days 4 and 5 post-transplant while syngeneic grafts continued to beat. All hearts showed ischemic damage. Allogeneic hearts showed cellular rejection by Day 1. 23Na MRS showed a steady elevation in signal in the 3 days prior to rejection and a sharp rise after rejection. 23Na MRS accurately identified full rejection and was also sensitive to the rejection process.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Waldrop SM,Alexander DZ,Lowry R,Winn KJ,Pearson TC,Constantinidis I

doi

10.1006/bbrc.1996.0902

subject

Has Abstract

pub_date

1996-06-14 00:00:00

pages

379-83

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(96)90902-X

journal_volume

223

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Deoxynucleoside triphosphate pool changes and UV-induced depression of DNA synthesis.

    abstract：:It has been reported that changes in deoxynucleotide pool levels following exposure to UV might lead to an overestimation of the UV-induced depression in DNA synthesis as analyzed by incorporation of 3H-thymidine (1). We attempted to determine the importance of such pool effects in two ways. First, we examined the gra...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(84)90292-4

    authors： Griffiths TD,Ling SY

    更新日期：1984-09-17 00:00:00

  • Expression of rat interleukin-5 and generation of neutralizing antiserum: a comparative study of rat IL-5 produced in Escherichia coli and insect cells.

    abstract：:A cDNA coding for rat IL-5 was obtained by RT-PCR from total spleen RNA. With the exception of a single a.a. replacement at position 85 (L-P), it is identical to the published sequence obtained by retroviral gene transfer. This cDNA was used to express biologically active recombinant IL-5 in E. coli and in insect cell...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9843

    authors： Pierrot C,Cocude C,Cêtre C,Godin C,Lafitte S,Capron M,Khalife J

    更新日期：1998-12-30 00:00:00

  • Ectopic expression of angiopoietin-1 promotes neuronal differentiation in neural progenitor cells through the Akt pathway.

    abstract：:In regions of adult neurogenesis, neural progenitor cells (NPCs) are found in close proximity to blood vessels within a so-called 'vascular niche'. Neurogenesis is linked to angiogenesis via certain growth factors. We propose that angiopoietin-1 (Ang1), which is similar to VEGF, has a unique role in neurogenesis indep...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.11.052

    authors： Bai Y,Cui M,Meng Z,Shen L,He Q,Zhang X,Chen F,Xiao J

    更新日期：2009-01-09 00:00:00

  • In vivo phosphorylation of isocitrate lyase from Escherichia coli D5H3G7.

    abstract：:This report describes the in vivo phosphorylation of isocitrate lyase and examines the possible consequences to the control of the Kreb's cycle and glyoxylate bypass. NADP-specific isocitrate dehydrogenase from E. coli was the first bacterial protein whose enzymic activity was shown to be modulated by reversible phosp...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)81177-x

    authors： Hoyt JC,Reeves HC

    更新日期：1988-06-16 00:00:00

  • Rapid fragmentation of vimentin in human skin fibroblasts exposed to tamoxifen: a possible involvement of caspase-3.

    abstract：:Tamoxifen (TAM), an anti-estrogen compound, is widely used for chemotherapy of breast cancer, although the molecular mechanisms underlying TAM cytotoxicity are obscure. Here, we show that TAM dramatically caused degradation of vimentin (VIM) in human skin fibroblasts, in a time and dose dependent manner. Addition of c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8799

    authors： Hashimoto M,Inoue S,Ogawa S,Conrad C,Muramatsu M,Shackelford D,Masliah E

    更新日期：1998-06-18 00:00:00

  • PRS3 encoding an essential subunit of yeast proteasomes homologous to mammalian proteasome subunit C5.

    abstract：:We found by computer analysis that a putative yeast proteasome subunit gene named PRS3 that encodes a protein very similar to subunit C5 of rat and human proteasomes is located immediately 3' to the ERD2 gene of Saccharomyces cerevisiae. The similarity of the primary structures of the two suggests that this subunit ma...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91753-d

    authors： Lee DH,Tanaka K,Tamura T,Chung CH,Ichihara A

    更新日期：1992-01-31 00:00:00

  • Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes.

    abstract：:Multi electrode arrays (MEAs) are increasingly used to detect external field potentials in electrically active cells. Recently, in combination with cardiomyocytes derived from human (induced) pluripotent stem cells they have started to become a preferred tool to examine newly developed drugs for potential cardiac toxi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.01.151

    authors： Tertoolen LGJ,Braam SR,van Meer BJ,Passier R,Mummery CL

    更新日期：2018-03-18 00:00:00

  • Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes.

    abstract：:Pathogenesis of Alzheimer's disease (AD) is characterized by accumulation of extracellular deposits of amyloid β-protein (Aβ) in the brain. The steady state level of Aβ in the brain is determined by the balance between its production and removal; the latter occurring through egress across blood and CSF barriers as wel...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.01.168

    authors： Yamamoto N,Tanida M,Ono Y,Kasahara R,Fujii Y,Ohora K,Suzuki K,Sobue K

    更新日期：2014-02-28 00:00:00

  • Identification of gene expression modifications in myostatin-stimulated myoblasts.

    abstract：:Myostatin belongs to the transforming growth factor beta superfamily and has been shown to function as an inhibitor of skeletal muscle proliferation and differentiation. To gain insight into the molecular mechanisms of myostatin function during myogenesis, differential display reverse transcription PCR was employed to...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.11.096

    authors： Yang W,Zhang Y,Ma G,Zhao X,Chen Y,Zhu D

    更新日期：2005-01-21 00:00:00

  • Cloning and characterization of the 5'-flanking region of the Ehox gene.

    abstract：:The paired-like homeobox-containing gene Ehox plays a role in embryonic stem cell differentiation and is highly expressed in the developing placenta and thymus. To understand the mechanisms of regulation of Ehox gene expression, the 5'-flanking region of the Ehox gene was isolated from a mouse BAC library. 5'-RACE ana...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.12.176

    authors： Lee WK,Kim YM,Malik N,Ma C,Westphal H

    更新日期：2006-03-03 00:00:00

  • UT-B1 urea transporter plays a noble role as active water transporter in C6 glial cells.

    abstract：:Since our experimental results suggest that UT-B1 functions as active water transporter against osmotic gradient in C6 glial cells, we report here for the first time the evidence for the active water transport. Exposure of C6 cells to a hyperosmotic solution containing glycerol or sucrose produced cell shrinkage due t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.10.097

    authors： Ogami A,Miyazaki H,Niisato N,Sugimoto T,Marunaka Y

    更新日期：2006-12-22 00:00:00

  • Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: possible effect on mitochondrial membranes.

    abstract：:The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, s...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(89)80210-4

    authors： Marcote MJ,González-Bosch C,Miralles VJ,Hernández-Yago J,Grisolía S

    更新日期：1989-01-16 00:00:00

  • The carbohydrate specificity of conglutinin and its homology to proteins in the hepatic lectin family.

    abstract：:Inhibition experiments with D-mannose oligosaccharides establish that conglutinin recognises terminal alpha 1----2 mannobiosyl units present in the glycopeptide of the alpha-chain of the complement component C3b. On the basis of its three domain structure and the homology of its N-terminal amino-acid sequence to that ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91402-1

    authors： Young NM,Leon MA

    更新日期：1987-03-13 00:00:00

  • 5-Fluorouracil enhances the chemosensitivity of gastric cancer to TRAIL via inhibition of the MAPK pathway.

    abstract：:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has the ability to selectively trigger cancer cell apoptosis and can be used as a target for tumor therapy. However, gastric cancer cells are usually insensitive to TRAIL so reducing this drug resistance may improve the treatment of gastric cancer. In thi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2021.01.006

    authors： Li H,Lv J,Guo J,Wang S,Liu S,Ma Y,Liang Z,Wang Y,Qi W,Qiu W

    更新日期：2021-01-18 00:00:00

  • Structural requirements of C-type natriuretic peptide for elevation of cyclic GMP in cultured vascular smooth muscle cells.

    abstract：:C-type natriuretic peptide (CNP), which was recently found to be a selective ligand for one of the two known natriuretic peptide receptor guanylyl cyclases (NPR-B), potently stimulates cGMP production in cultured rat vascular smooth muscle cells (VSMC) and exerts potent antiproliferative effects on the cells. To inves...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80284-0

    authors： Furuya M,Tawaragi Y,Minamitake Y,Kitajima Y,Fuchimura K,Tanaka S,Minamino N,Kangawa K,Matsuo H

    更新日期：1992-03-31 00:00:00

  • Cytochrome P-450-catalyzed formation of 20-hydroxy-ecdysone in larval housefly mitochondria.

    abstract：:Six forms of cytochrome P-450 in the mitochondria of larvae from Musca domestica were isolated by solubilization with CHAPS followed by ammonium sulfate fractionation and HPLC on an anion-exchange column. Forms 1, 2, 3, 5, and 6 catalyzed the formation of 20-hydroxy-ecdysone from ecdysone in the presence of NADPH and ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)91018-n

    authors： Srivatsan J,Weirich M,Agosin M

    更新日期：1990-02-14 00:00:00

  • Temperature dependence of the flexural rigidity of single microtubules.

    abstract：:Although the flexural rigidity of a microtubule has previously been estimated by various methods, its temperature dependence has never been systematically examined. Here, we measured the flexural rigidity of a single taxol-stabilized microtubule from thermal fluctuation of the free end of a microtubule, the other end ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.11.162

    authors： Kawaguchi K,Ishiwata S,Yamashita T

    更新日期：2008-02-15 00:00:00

  • Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament.

    abstract：:Wound healing in ligaments is a complex process which leads to functionally impaired scar tissue, even after extended time postinjury. To investigate the potential role of proteinases and inhibitors, as well as potential regulators of their expression, mRNA levels for collagenase, stromelysin, urokinase, PAI-1, and TI...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9734

    authors： Reno C,Boykiw R,Martinez ML,Hart DA

    更新日期：1998-11-27 00:00:00

  • Characterization of the platelet-derived growth factor beta-receptor kinase activity by use of synthetic peptides.

    abstract：:Synthetic peptides derived from the sequence surrounding tyrosine-857 in the human platelet-derived growth factor (PDGF) beta-receptor were used to elucidate the requirement for length and presence of negative and positively charged amino acids in substrates of the PDGF beta-receptor protein tyrosine kinase. The measu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90669-e

    authors： Rönnstrand L,Sorokin A,Engström U,Heldin CH

    更新日期：1990-03-30 00:00:00

  • Interleukin-2 binds to ganglioside GD(1b).

    abstract：:We have developed a solid matrix immunoassay to determine the binding of interleukin-2 (IL-2) to specific gangliosides. The assay establishes that recombinant human IL-2 binds to ganglioside GD(1b) but not to any other gangliosides (GM(1), GM(2), GM(3), GD(1a), GD(2), GD(3), and GT(1b)). The binding varies with the ra...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.4797

    authors： Ravindranath MH,Gonzales A,Soh D,Nishimoto K,Tam WY,Bilchik A,Morton DL,O'Day S

    更新日期：2001-05-04 00:00:00

  • Insertional mutagenesis in the tailspike protein of bacteriophage P22.

    abstract：:The tailspike protein (TSP) of bacteriophage P22 is a homotrimeric multifunctional protein responsible for recognition and hydrolysis of Salmonella typhimurium host receptors. Once properly folded, TSP shows an unusual stability to temperature and detergent denaturation, prompting the analysis of TSP as a framework fo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8285

    authors： Carbonell X,Villaverde A

    更新日期：1998-03-17 00:00:00

  • ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue.

    abstract：:ATP-binding cassette transporter D2 (D2) is an ABC half transporter that is thought to promote the transport of very long-chain fatty acyl-CoAs into peroxisomes. Both D2 and peroxisomes increase during adipogenesis. Although peroxisomes are essential to both catabolic and anabolic lipid metabolism, their function, and...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.11.046

    authors： Liu X,Liu J,Lester JD,Pijut SS,Graf GA

    更新日期：2015-01-02 00:00:00

  • HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury.

    abstract：:Diabetes mellitus (DM) is a risk factor for abnormal heart development, but the molecular mechanism remains obscure. Histone deacetylase 11 (HDAC11), the most recently identified histone deacetylase, is the sole member of class IV HDACs. However, its role in diabetic cardiac injury is still poorly understood. In the p...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.04.090

    authors： Fan XD,Wan LL,Duan M,Lu S

    更新日期：2018-09-05 00:00:00

  • An explanation for the disparate effects of synthetic peptides corresponding to human follicle-stimulating hormone beta-subunit receptor binding regions (33-53) and (81-95) and their serine analogs on steroidogenesis in cultured rat Sertoli cells.

    abstract：:We have recently reported that synthetic peptide amides corresponding to regions of human FSH beta-subunit, hFSH-beta-(33-53) and hFSH-beta-(81-95), bind to receptor and stimulate estradiol biosynthesis by cultured rat Sertoli cells. Because of experimental difficulties caused by the presence of free sulfhydryl groups...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1010

    authors： Grasso P,Crabb JW,Reichert LE Jr

    更新日期：1993-01-15 00:00:00

  • Modulation of nucleotide pyrophosphatase in plasmacytoma cells.

    abstract：:The effect of glucocorticoid hormones on the protein responsible for both nucleotide pyrophosphatase (EC 3.6.1.9) and alkaline phosphodiesterase I (EC 3.1.4.1) activities was examined in murine MOPC 315 plasmacytoma cells. Incubation of these cells with dexamethasone resulted in parallel increases in pyrophosphatase a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91613-h

    authors： Rebbe NF,Hickman S

    更新日期：1991-03-15 00:00:00

  • Irisin ameliorates depressive-like behaviors in rats by regulating energy metabolism.

    abstract：:Depression is a common psychiatric disorder that affects millions of people around the world, however, little is known about the pathophysiology of depression and the therapeutic strategy for anti-depression. In this study, we investigated the role of irisin, a regulator of energy metabolism, in the modulation of depr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.04.047

    authors： Wang S,Pan J

    更新日期：2016-05-20 00:00:00

  • Interaction of activated Rab5 with actin-bundling proteins, L- and T-plastin and its relevance to endocytic functions in mammalian cells.

    abstract：:Rab5 is a GTP-binding protein that is crucial for endocytic machinery functions. We previously identified L-plastin as a binding protein for Rab5, using an affinity column with constitutively active Rab5. L- and T-plastin are isoforms of a plastin protein family belonging to actin-bundling proteins that are implicated...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.03.082

    authors： Hagiwara M,Shinomiya H,Kashihara M,Kobayashi K,Tadokoro T,Yamamoto Y

    更新日期：2011-04-15 00:00:00

  • Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner.

    abstract：:Protein kinase C (PKC) has recently emerged as mediator of corticotropin-releasing hormone (CRH) effects. Aim of the present study was to study the effects of CRH on each PKC isoenzyme. As a model we have used the PC12 rat pheochromocytoma cell line, expressing the CRH type 1 receptor (CRHR1). Our data were as follows...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.12.078

    authors： Dermitzaki E,Tsatsanis C,Charalampopoulos I,Androulidaki A,Alexaki VI,Castanas E,Gravanis A,Margioris AN

    更新日期：2005-02-18 00:00:00

  • Activation of prokaryotic translation by antisense oligonucleotides binding to coding region of mRNA.

    abstract：:A few examples of translational activation by antisense small noncoding RNAs (sRNAs) have already been discovered in prokaryotic cells, and all of them are through a sense-antisense interaction at the 5'-untranslated region (5'-UTR) of target mRNAs. Here, we report a novel phenomenon of translational activation of pro...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.10.072

    authors： Hayashi G,Hong C,Hagihara M,Nakatani K

    更新日期：2012-12-07 00:00:00

  • Changes of free fatty acids and acyl-CoAs in rat brain hippocampal slice with tetraethylammonium-induced long-term potentiation.

    abstract：:We investigated the role of acyl-CoAs during induction and maintenance of long-term potentiation in rat brain hippocampus. Changes of acyl-CoA and free fatty acids (FFA) in hippocampus were measured during tetraethylammonium (TEA)-induced LTP. Results indicated that concentrations of acyl-CoAs and FFAs in slices were ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.1867

    authors： Zhang Q,Yoshida S,Sakai K,Liu J,Fukunaga K

    更新日期：2000-01-07 00:00:00