Variability in myosteatosis and insulin resistance induced by high-fat diet in mouse skeletal muscles.

abstract：:Secretory leukoprotease inhibitor (SLPI) is an anti-inflammatory protein present in respiratory secretions. Whilst epithelial cell SLPI is extensively studied, neutrophil associated SLPI is poorly characterised. Neutrophil function including chemotaxis and degranulation of proteolytic enzymes involves changes in cytos...

journal_title：BioMed research international

authors： Reeves EP,Banville N,Ryan DM,O'Reilly N,Bergin DA,Pohl K,Molloy K,McElvaney OJ,Alsaleh K,Aljorfi A,Kandalaft O,O'Flynn E,Geraghty P,O'Neill SJ,McElvaney NG

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:This study mainly aimed to explore the association between brain-derived neurotropic factor (BDNF) Val66Met polymorphism and posttraumatic stress disorder (PTSD) among flood survivors in China. METHODS:Individuals who experienced the 1998 Dongting Lake flood in Southeast Huarong, China, were enrolled in this...

journal_title：BioMed research international

authors： Dai W,Kaminga AC,Wu X,Wen SW,Tan H,Yan J,Deng J,Lai Z,Liu A

更新日期：2017-01-01 00:00:00

abstract：:ELABELA (ELA) is considered to be implicated in the pathophysiology of preeclampsia (PE), since ELA-deficient mice exhibited PE-like symptoms and infusion of exogenous ELA normalized the gestational hypertension (GH) and proteinuria. However, no evidence show that circulating ELA is deficient in early placental develo...

journal_title：BioMed research international

authors： Ma S,Guo C,Zhang J,Long S,Tan H,You Y

更新日期：2020-09-28 00:00:00

abstract：:Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...

journal_title：BioMed research international

authors： Farini A,Sitzia C,Erratico S,Meregalli M,Torrente Y

更新日期：2014-01-01 00:00:00

abstract：Objectives:Childhood malnutrition is major health concern in many low- and middle-income countries, including Vietnam. It was a major risk factor for child mortality and adult ill-health. Malnutrition could increase the risk of serious infections; conversely current diseases also had a negative impact on the growth of ...

journal_title：BioMed research international

authors： Huynh G,Huynh QHN,Nguyen NHT,Do QT,Khanh Tran V

更新日期：2019-02-05 00:00:00

abstract：:Background. Aortic valve calcification (AVC) is a common feature of aging and is related to coronary artery disease. Although abdominal visceral adipose tissue (VAT) plays fundamental roles in coronary artery disease, the relationship between abdominal VAT and AVC is not fully understood. Methods. We investigated 259 ...

journal_title：BioMed research international

authors： Oikawa M,Owada T,Yamauchi H,Misaka T,Machii H,Yamaki T,Sugimoto K,Kunii H,Nakazato K,Suzuki H,Saitoh S,Takeishi Y

更新日期：2016-01-01 00:00:00

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：:Introduction. Infection and apoptosis are combined triggers for inflammation in dental tissues. Octamer-binding transcription factor 4-B1 (OCT4B1), a novel spliced variant of OCT4 family, could respond to the cellular stress and possess antiapoptotic property. However, its specific role in dental pulpitis remains unkn...

journal_title：BioMed research international

authors： Liu L,Huang R,Yang R,Wei X

更新日期：2017-01-01 00:00:00

abstract：:Among other diseases characterized by the onset of cachexia, congestive heart failure takes a place of relevance, considering the high prevalence of this pathology in most European countries and in the United States, and is undergoing a rapid increase in developing countries. Actually, only few models of cardiac cache...

journal_title：BioMed research international

authors： Sala V,Gatti S,Gallo S,Medico E,Cantarella D,Cimino J,Ponzetto A,Crepaldi T

更新日期：2016-01-01 00:00:00

abstract：Background:Physical activity has been found to maintain and improve cognitive function and consequently improve health-related quality of life (HRQoL). The relationships between different types of physical activities, cognitive function, and HRQoL have not been studied sufficiently and compared in different age and gen...

journal_title：BioMed research international

authors： Alsubaie SF,Alkathiry AA,Abdelbasset WK,Nambi G

更新日期：2020-12-18 00:00:00

abstract：:This study aimed to develop a new biodegradable stent for peripheral artery disease (PAD) that could provide sufficient radial force to maintain long-term patency and flexibility. All self-expandable hybrid biodegradable stents were designed by using a knitting structure composed of poly-L-lactic acid (PLLA) and nitin...

journal_title：BioMed research international

authors： Lee JH,Kim SJ,Park SI,Ko YG,Choi D,Hong MK,Jang Y

更新日期：2016-01-01 00:00:00

abstract：:Previously, a novel technique was proposed to quantify the relationship between the muscle stiffness and its nonfatigue contraction intensity. The method extended the measured range of isometric contraction to 100% maximum voluntary contraction (MVC) using an ultrasonic shear wave measurement setup. Yet, it has not be...

journal_title：BioMed research international

authors： Wang CZ,Guo JY,Li TJ,Zhou Y,Shi W,Zheng YP

更新日期：2017-01-01 00:00:00

abstract：Objective:This study is aimed at evaluating the effects of platelet-rich plasma (PRP) on proliferation, viability, and odontogenic differentiation of neural crest stem-like cells (NCSCs) derived from human dental apical papilla. Materials and Methods:Cells from apical papillae were obtained and then induced to form ne...

journal_title：BioMed research international

authors： Li J,Xiang L,Guan C,Yang X,Hu X,Zhang X,Zhang W

更新日期：2020-05-09 00:00:00

abstract：:Diabetes mellitus is a disease which has affected 415 million patients in 2015. In an effort to replace the significant demands on transplantation and morbidity associated with transplantation, the production of β-like cells differentiated from induced pluripotent stem cells (iPSCs) was evaluated. This approach is ass...

journal_title：BioMed research international

authors： Wan J,Huang Y,Zhou P,Guo Y,Wu C,Zhu S,Wang Y,Wang L,Lu Y,Wang Z

更新日期：2017-01-01 00:00:00

abstract：Background:Spinal cord injury (SCI) is often associated with long-term impairments related to functional limitations in the sensorimotor system. The use of virtual reality (VR) technology may lead to increased motivation and engagement, besides allowing a wide range of possible tasks/exercises to be implemented in reha...

journal_title：BioMed research international

authors： de Araújo AVL,Neiva JFO,Monteiro CBM,Magalhães FH

更新日期：2019-11-13 00:00:00

abstract：:Glioblastoma (GBM) is a primary neuroepithelial tumor of the central nervous system, characterized by an extremely aggressive clinical phenotype. Patients with GBM have a poor prognosis and only 3-5% of them survive for more than 5 years. The current GBM treatment standards include maximal resection followed by radiot...

journal_title：BioMed research international

authors： Szopa W,Burley TA,Kramer-Marek G,Kaspera W

更新日期：2017-01-01 00:00:00

abstract：:In continuance of our search for anticancer agents, we report herein the synthesis and anticancer activity of some novel oxadiazole analogues. The compounds were screened for anticancer activity as per National Cancer Institute (NCI US) protocol on leukemia, melanoma, lung, colon, CNS, ovarian, renal, prostate, and br...

journal_title：BioMed research international

authors： Ahsan MJ,Sharma J,Singh M,Jadav SS,Yasmin S

更新日期：2014-01-01 00:00:00

abstract：:In vitro studies reveal that androgens, oestrogens, and their metabolites play a crucial role in prostate homeostasis. Most of the studies evaluated intraprostatic hormone metabolism using cell lines or preprocessed specimens. Using an ex vivo model of intact tissue cultures with preserved architecture, we characteriz...

journal_title：BioMed research international

authors： Gianfrilli D,Pierotti S,Pofi R,Leonardo C,Ciccariello M,Barbagallo F

更新日期：2014-01-01 00:00:00

abstract：:Biolasol is a newly developed solution for storing the liver, pancreas, kidneys, and heart by simple hypothermia. It exhibits high efficacy in maintaining structural and functional integrity of the graft prior to its transplantation. The solution was modified by the addition of ascorbic acid (0.088g/l) and ascorbic ac...

journal_title：BioMed research international

authors： Ostróżka-Cieślik A,Dolińska B,Ryszka F

更新日期：2018-11-12 00:00:00

abstract：Objective:To explore the ability of asiatic acid to interfere with the invasion and proliferation of breast cancer cells by inhibiting WAVE3 expression and activation through the PI3K/AKT signaling pathway. Methods:The MDA-MB-231 cells with strong invasiveness were screened by transwell assay, and plasmids with high e...

journal_title：BioMed research international

authors： Gou XJ,Bai HH,Liu LW,Chen HY,Shi Q,Chang LS,Ding MM,Shi Q,Zhou MX,Chen WL,Zhang LM

更新日期：2020-02-10 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00

abstract：:Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The auth...

journal_title：BioMed research international

authors： Zhao D,Liu B,Wang B,Yang L,Xie H,Huang S,Zhang Y,Wei X

更新日期：2015-01-01 00:00:00

abstract：:Severe stages of acute, colonic diverticulitis can progress into intestinal perforations with peritonitis. In such cases, urgent treatment is needed, and Hartmann's procedure is the standard treatment for cases with fecal peritonitis. Peritoneal lavage may be an alternative to resection for acute diverticulitis with p...

journal_title：BioMed research international

authors： Hupfeld L,Burcharth J,Pommergaard HC,Rosenberg J

更新日期：2014-01-01 00:00:00

abstract：:Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or r...

journal_title：BioMed research international

authors： Lee W,Kim Y,Choi H,Kim H,Lee S,Lee H,Chee H,Kim J,Hwang J,Lee S,Kim Y,Cho S,Ryu S,Park S

更新日期：2017-01-01 00:00:00

abstract：:A novel methylamine-selective amperometric bienzyme biosensor based on recombinant primary amine oxidase isolated from the recombinant yeast strain Saccharomyces cerevisiae and commercial horseradish peroxidase is described. Two amine oxidase preparations were used: free enzyme (AMO) and covalently immobilized on the ...

journal_title：BioMed research international

authors： Stasyuk NY,Smutok OV,Zakalskiy AE,Zakalska OM,Gonchar MV

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To investigate the correlation of outer retinal layers (ORL) thickness and visual acuity (VA) in patients with diabetic macular edema (DME). METHODS:Consecutive DME patients seen at the Retina Clinic of The University of Hong Kong were recruited for OCT assessment. The ORL thickness was defined as the distance...

journal_title：BioMed research international

authors： Wong RL,Lee JW,Yau GS,Wong IY

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Fever in systemic lupus erythematosus (SLE) can be caused by infection or flare-up of the disease. This study aimed to determine whether the ratio of the level of erythrocyte-bound C4d to that of complement receptor 1 (C4d/CR1) can serve as a useful biomarker in the differentiation between infection and flare...

journal_title：BioMed research international

authors： Chen CH,Tai SB,Chen HC,Yang DH,Peng MY,Lin YF

更新日期：2015-01-01 00:00:00

abstract：:Objectives. Osteopontin (OPN) is overexpressed in breast cancers, while its clinical and prognostic significance remained unclear. This study aimed to assess the prognostic value of OPN, especially its splice variants, in breast cancers. Methods. Data were extracted from eligible studies concerning the OPN and OPN-c e...

journal_title：BioMed research international

authors： Hao C,Wang Z,Gu Y,Jiang WG,Cheng S

更新日期：2016-01-01 00:00:00

abstract：:Aim. To refine the decellularization protocol of whole porcine liver, which holds great promise for liver tissue engineering. Methods. Three decellularization methods for porcine livers (1% sodium dodecyl sulfate (SDS), 1% Triton X-100 + 1% sodium dodecyl sulfate, and 1% sodium deoxycholate + 1% sodium dodecyl sulfate...

journal_title：BioMed research international

authors： Wu Q,Bao J,Zhou YJ,Wang YJ,Du ZG,Shi YJ,Li L,Bu H

更新日期：2015-01-01 00:00:00

abstract：Background:Ischemic heart disease (IHD) is the major cause of death in patients with cardiovascular disease. Cardiac remodeling is a common pathological change following myocardial infarction (MI), and cardiomyocyte apoptosis plays a key role in this change. Transcription factor recombination signal-binding protein-J (...

journal_title：BioMed research international

authors： He Y,Pang S,Huang J,Zhu K,Tong J,Tang Y,Ma G,Chen L

更新日期：2018-07-03 00:00:00