Oculocutaneous albinism in sub-Saharan Africa: adverse sun-associated health effects and photoprotection.

Abstract:

:Oculocutaneous albinism (OCA) is a genetically inherited autosomal recessive condition. Individuals with OCA lack melanin and therefore are susceptible to the harmful effects of solar ultraviolet radiation, including extreme sun sensitivity, photophobia and skin cancer. OCA is a grave public health issue in sub-Saharan Africa with a prevalence as high as 1 in 1000 in some tribes. This article considers the characteristics and prevalence of OCA in sub-Saharan African countries. Sun-induced adverse health effects in the skin and eyes of OCA individuals are reviewed. Sun exposure behavior and the use of photoprotection for the skin and eyes are discussed to highlight the major challenges experienced by these at-risk individuals and how these might be best resolved.

journal_name

Photochem Photobiol

authors

Wright CY,Norval M,Hertle RW

doi

10.1111/php.12359

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

27-32

issue

1

eissn

0031-8655

issn

1751-1097

journal_volume

91

pub_type

杂志文章,评审
  • Circadian gating of photoinduction of commitment to cell-cycle transitions in relation to photoperiodic control of cell reproduction in Euglena.

    abstract::A novel type of circadian and photoperiodic control of the cell division cycle was found in photoautotrophic Euglena gracilis. When algae entrained to 24 h light-dark (LD) cycles (14 h L) were transferred to continuous darkness (DD) at the eighth hour of the final LD photoperiod, cell-cycle transition was arrested in ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2002)076<0105:cgopoc>2.0.co;2

    authors: Hagiwara SY,Bolige A,Zhang Y,Takahashi M,Yamagishi A,Goto K

    更新日期:2002-07-01 00:00:00

  • Detection of modified tyrosines as an inflammation marker in a photo-aged skin model.

    abstract::Reactive nitrogen species, produced during the process of inflammation induced by various factors including UV radiation, modify amino acids in crucial proteins. It is assumed that skin tissue is more likely to be modified, as it is located at the outer layer of a body that is exposed to UV radiation on a daily basis....

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2006-07-24-RA-978

    authors: Ishitsuka Y,Maniwa F,Koide C,Douzaki N,Kato Y,Nakamura Y,Osawa T

    更新日期:2007-05-01 00:00:00

  • Increasing Temperature Counteracts the Negative Effect of UV Radiation on Growth and Photosynthetic Efficiency of Microcystis aeruginosa and Raphidiopsis raciborskii.

    abstract::High temperature can promote cyanobacterial blooms, whereas ultraviolet radiation (UVR) can potentially depress cyanobacterial growth by damaging their photosynthetic apparatus. Although the damaging effect of UVR has been well documented, reports on the interactive effects of UV radiation exposure and warming on cyan...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13377

    authors: Noyma NP,Mesquita MCB,Roland F,Marinho MM,Huszar VLM,Lürling M

    更新日期:2021-01-04 00:00:00

  • Autofluorescence spectroscopy of optically trapped cells.

    abstract::Cellular autofluorescence spectra were monitored in a single-beam gradient force optical trap ("optical tweezers") in order to probe the physiological effects of near infrared and UVA (320-400 nm) microirradiation. Prior to trapping, Chinese hamster ovary cells exhibited weak UVA-excited autofluorescence with maxima a...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1995.tb09143.x

    authors: König K,Liu Y,Sonek GJ,Berns MW,Tromberg BJ

    更新日期:1995-11-01 00:00:00

  • Molecular changes during the photooxidation of alpha-crystallin in the presence of uroporphyrin.

    abstract::Singlet oxygen reacts preferentially with three amino acids in proteins, His, Trp and Met. In order to study the specific molecular events that result from such oxidations, calf alpha-crystallin was photooxidized in the presence of uroporphyrin and the reactions were investigated by high performance liquid chromatogra...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb02330.x

    authors: Dillon J,Chiesa R,Wang RH,McDermott M

    更新日期:1993-03-01 00:00:00

  • Immunotoxic effects of cis-urocanic acid exposure in C57BL/6N and C3H/HeN mice.

    abstract::Exposure to ultraviolet radiation results in increased levels of intradermal cis-urocanic acid (cUCA) and alters cutaneous immunity by interfering with processing and presentation of antigen by Langerhans cells. Reports on effects of systemic immunotoxicity with 30 day cUCA exposure in laboratory rodents include thymi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2003)077<0383:ieocae>2.0.co;2

    authors: Prater MR,Gogal RM Jr,De Fabo EC,Longstreth J,Holladay SD

    更新日期:2003-04-01 00:00:00

  • In vitro photodynamic effects of lysyl chlorin p6: cell survival, localization and ultrastructural changes.

    abstract::The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb04948.x

    authors: Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

    更新日期:1993-11-01 00:00:00

  • Mutants of Ca2+ -regulated Photoprotein Obelin for Site-specific Conjugation.

    abstract::Color variants of Ca2+ -regulated photoprotein obelin were shown to be an important tool for dual-analyte binding assay. To provide site-directed conjugation with biospecific molecules, several obelin color mutants carrying unique cysteine residues were obtained and characterized for their novel properties. A pair of ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/php.12712

    authors: Krasitskaya VV,Burakova LP,Komarova AA,Bashmakova EE,Frank LA

    更新日期:2017-03-01 00:00:00

  • Ex vivo fluorescence imaging of normal and malignant urothelial cells to enhance early diagnosis.

    abstract::Urinary cytology is a noninvasive and unconstraining technique for urothelial cancer diagnosis but lacks sensitivity for detecting low-grade lesions. In this study, the fluorescence properties of classical Papanicolaou-stained urothelial cytological slides from patients or from cell lines were monitored to investigate...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2007.00079.x

    authors: Steenkeste K,Lécart S,Deniset A,Pernot P,Eschwège P,Ferlicot S,Lévêque-Fort S,Briandet R,Fontaine-Aupart MP

    更新日期:2007-09-01 00:00:00

  • From San Luis, A Few Words of Gratitude.

    abstract::The Photochemical Research Group from San Luis (Argentina) highlights the contributions of Dr. Norman Andino García to the development of the group as a way to show him our gratitude for all his support. ...

    journal_title:Photochemistry and photobiology

    pub_type: 社论

    doi:10.1111/php.12988

    authors: Ferrari G,Montaña MP

    更新日期:2018-11-01 00:00:00

  • Photoenolization of o-Methylvalerophenone Ester Derivative.

    abstract::Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12590

    authors: Das A,Lao EA,Gudmundsdottir AD

    更新日期:2016-05-01 00:00:00

  • Fluorescence lifetimes of protochlorophyllide in plants with different proportions of short-wavelength and long-wavelength protochlorophyllide spectral forms.

    abstract::Dark-grown leaves of maize (Zea mays), wheat (Triticum aestivum), wild-type pea (Pisum sativum) and its light-independent photomorphogenesis mutant (lip1) have different proportions of protochlorophyllide (Pchlide) forms as revealed by low-temperature fluorescence emission spectra. Four discrete spectral forms of Pchl...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2003)078<0205:flopip>2.0.co;2

    authors: Myśliwa-Kurdziel B,Amirjani MR,Strzałka K,Sundqvist C

    更新日期:2003-08-01 00:00:00

  • NLOphoric Triphenylamine Derived Donor-π-Acceptor-π-Donor Based Colorants: Synthesis, Spectroscopic, Density Functional Theory and Z-scan Studies.

    abstract::Three Donor-π-Acceptor-π-Donor type styryl dyes (5a-c) with different secondary donors are synthesized and characterized to study their nonlinear and linear optical properties. The structure-property relationships of the dyes are described in the light of systematic photophysical and theoretical investigations. The ph...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13089

    authors: Raikwar MM,Mathew E,Varghese M,Joe IH,Nethi SN

    更新日期:2019-07-01 00:00:00

  • Cyclobutane dimers and (6-4) photoproducts in human cells are mended with the same patch sizes.

    abstract::The size of excision repair patches corresponding to excision of (6-4) pyrimidine-pyrimidone photoproducts and (5-5, 6-6) cyclobutane dimers have been independently determined by using bromodeoxyuridine substitution and density increases in isopycnic gradients of small DNA fragments. The two classes of photoproducts w...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1991.tb02033.x

    authors: Cleaver JE,Jen J,Charles WC,Mitchell DL

    更新日期:1991-09-01 00:00:00

  • Time-Resolved Studies of Light Propagation in Crassula and Phaseolus Leaves.

    abstract::Abstract- Time-resolved transmittance was used to extract in vivo optical properties of leaves of green plants experimentally. In time-resolved transmittance measurements an ultrashort light pulse is directed onto the surface of the object and the transmitted light is measured with a time resolution in the range of pi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1999.tb03281.x

    authors: Johansson J,Berg R,Pifferi A,Svanberg S,Björn LO

    更新日期:1999-02-01 00:00:00

  • Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

    abstract::Ultraviolet (UV) radiation is among the most prevalent environmental factors that influence human health and disease. Even 1 h of UV irradiation extensively damages the genome. To cope with resulting deleterious DNA lesions, cells activate a multitude of DNA damage response pathways, including DNA repair. Strikingly, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13245

    authors: Lee JW,Ratnakumar K,Hung KF,Rokunohe D,Kawasumi M

    更新日期:2020-05-01 00:00:00

  • Scrambled self-assembly of bacteriochlorophylls c and e in aqueous Triton X-100 micelles.

    abstract::Bacteriochlorophyll (BChl) e was coassembled with BChl c in Triton X-100 micelles in aqueous solutions. The Qy absorption bands of the coaggregates were positioned between those of aggregates consisting solely of BChl c or e. The electronic absorption spectra of the coaggregates could not be reproduced by linear combi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12219

    authors: Saga Y,Saiki T,Takahashi N,Shibata Y,Tamiaki H

    更新日期:2014-05-01 00:00:00

  • Asiatic Acid Glucosamine Salt Alleviates Ultraviolet B-induced Photoaging of Human Dermal Fibroblasts and Nude Mouse Skin.

    abstract::Herbal extracts including asiatic acid (AA) have become popular candidates of anti-photoaging agents due to their anti-inflammatory and antioxidant properties and minimal side effect. Nevertheless, low bioavailability due to poor solubility limits their practical application. In this study, a highly bioavailable form ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13160

    authors: Huang J,Tu T,Wang W,Zhou G,Zhang W,Wu X,Liu W

    更新日期:2020-01-01 00:00:00

  • DNA damage and repair in Gorlin syndrome and normal fibroblasts after aminolevulinic acid photodynamic therapy: a comet assay study.

    abstract::Using normal, untransformed, human fibroblasts, the effectiveness of aminolevulinic (ALA)-mediated photodynamic therapy (PDT) was investigated in terms of both clonogenic survival and DNA damage. The response of normal fibroblasts was then compared with Gorlin syndrome-derived fibroblasts (basal cell nevus syndrome [B...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2003)078<0337:ddarig>2.0.co;2

    authors: Haylett AK,Ward TH,Moore JV

    更新日期:2003-10-01 00:00:00

  • Role of nuclear factor-kappa B in colon cancer cell apoptosis mediated by aminopyropheophorbide photosensitization.

    abstract::Aminopyropheophorbide (APP) is a second generation of photosensitizer for photodynamic therapy (PDT). We demonstrated that APP strongly absorbed red light and, after being taken up by colon cancer cells (HCT-116 cells), was localized in cytoplasmic and internal membranes but not in mitochondria. The APP-mediated photo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Matroule JY,Hellin AC,Morlière P,Fabiano AS,Santus R,Merville MP,Piette J

    更新日期:1999-10-01 00:00:00

  • Preparation of new magnetic nanocatalysts based on TiO2 and ZnO and their application in improved photocatalytic degradation of dye pollutant under visible light.

    abstract::Photocatalytic degradation of methyl orange (MO) as a model of an organic pollution was accomplished with magnetic and porous TiO(2)/ZnO/Fe(3)O(4)/PANI and ZnO/Fe(3)O(4)/PANI nanocomposites under visible light irradiation. The structures of nanocomposites were characterized by various techniques including UV-Vis absor...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2012.01209.x

    authors: Nabid MR,Sedghi R,Gholami S,Oskooie HA,Heravi MM

    更新日期:2013-01-01 00:00:00

  • Effect of solvent-water mixtures on the prototropic equilibria of fluorescein and on the spectral properties of the monoanion

    abstract::A spectral resolution procedure was used to resolve the absorption, excitation and emission spectra of the fluorescein monoanion in a number of solvent-water mixtures. This permitted an analysis of the effect of the solvent environment on the spectral properties of the monoanion and on the lactone/monoanion/dianion tr...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2000)072<0179:eoswmo>2.0.co;2

    authors: Klonis N,Sawyer WH

    更新日期:2000-08-01 00:00:00

  • Entropy changes drive the electron transfer reaction of triplet flavin mononucleotide from aromatic amino acids in cation-organized aqueous media. A laser-induced optoacoustic study.

    abstract::The thermodynamic parameters for the formation of the free radicals upon electron transfer quenching of the flavin triplet state (3FMN) by tryptophan and tyrosine, Delta(FR)H and Delta(FR)V, were obtained in aqueous solution by the application of laser-induced optoacoustic spectroscopy at various temperatures. The Del...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2005-03-22-RA-468

    authors: Crovetto L,Martínez-Junza V,Braslavsky SE

    更新日期:2006-01-01 00:00:00

  • Ab initio quantum chemical investigation of the first steps of the photocycle of phototropin: a model study.

    abstract::Phototropin is a blue light-activated photoreceptor that plays a dominant role in the phototropism of plants. The protein contains two subunits that bind flavin mononucleotide (FMN), which are responsible for the initial steps of the light-induced reaction. It has been proposed that the photoexcited flavin molecule ad...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2003)077<0101:aiqcio>2.0.co;2

    authors: Neiss C,Saalfrank P

    更新日期:2003-01-01 00:00:00

  • Cooperative phenomena in two-pulse, two-color laser photocoagulation of cutaneous blood vessels.

    abstract::A novel laser system has been developed to study the effects of multiple laser pulses of differing wavelengths on cutaneous blood vessels in vivo, using the hamster dorsal skin flap preparation and in vitro, using cuvettes of whole or diluted blood. The system permits sequenced irradiation with well-defined intrapulse...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)073<0642:cpitpt>2.0.co;2

    authors: Barton JK,Frangineas G,Pummer H,Black JF

    更新日期:2001-06-01 00:00:00

  • Enhancement of palladium-porphyrin room temperature phosphorescence by alkaline earth metal in deoxycholate aggregates solution.

    abstract::Room temperature phosphorescence (RTP) of three palladium (Pd)-phorphyrins in air-saturated solution of sodium deoxycholate (NaDC) aggregates was measured. RTP of Pd-meso-tetrakis (4-carboxyphenyl) porphyrin (Pd-TCPP) was obviously enhanced in NaDC-aggregates mediated by alkaline earth metal (AEM). Under the same expe...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2011.00927.x

    authors: Wang YT,Wang XW,Zhang Y

    更新日期:2011-07-01 00:00:00

  • Infrared radiation influence on molt and regeneration of Neohelice granulata Dana, 1851 (Grapsidae, Sesarminae).

    abstract::This paper analyzes the influence of infrared radiation (IR) on regeneration, after autotomy of limb buds of Neohelice granulata and consequently the time molt. Eyestalks were ablated to synchronize the start of molt. Afterward, animals were autotomized of five pereopods and divided into control and irradiated groups....

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2009.00570.x

    authors: Gonzalez VC,Lena AB,Espindola WA,de Souza Votto AP,Jorge MB,de Moraes Vaz Batista Filgueira D,Bianchini A,Sérgio Varela Júnior A,Nery LE,Trindade GS

    更新日期:2009-09-01 00:00:00

  • Hypothesis--ultraviolet-B irradiance and vitamin D reduce the risk of viral infections and thus their sequelae, including autoimmune diseases and some cancers.

    abstract::Many viral infections reach clinical significance in winter, when it is cold, relative humidity is lowest and vitamin D production from solar ultraviolet-B irradiation is at its nadir. Several autoimmune diseases, such as multiple sclerosis, type 1 diabetes mellitus and asthma, are linked to viral infections. Vitamin ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-1097.2007.00266.x

    authors: Grant WB

    更新日期:2008-03-01 00:00:00

  • Chitosan nanoparticles for antimicrobial photodynamic inactivation: characterization and in vitro investigation.

    abstract::The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate its ability to pote...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2012.01101.x

    authors: Chen CP,Chen CT,Tsai T

    更新日期:2012-05-01 00:00:00

  • Generation of free radicals by emodic acid and its [D-Lys6]GnRH-conjugate.

    abstract::In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Emodin is a naturally occurring anthraquinone which is ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0226:gofrbe>2.0.co;2

    authors: Rahimipour S,Bilkis I,Péron V,Gescheidt G,Barbosa F,Mazur Y,Koch Y,Weiner L,Fridkin M

    更新日期:2001-08-01 00:00:00