To treat or not to treat? Pilot survey for minor and rapidly improving stroke.

abstract：BACKGROUND AND PURPOSE:In addition to low-density lipoprotein (LDL) cholesterol, small, dense LDL particles and oxidative modification of LDL have been linked to the pathogenesis of atherosclerosis. The present study was aimed at investigating the association between carotid artery intima-media thickness (IMT) and LDL ...

journal_title：Stroke

authors： Liu ML,Ylitalo K,Nuotio I,Salonen R,Salonen JT,Taskinen MR

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke on board aircraft has been reported in retrospective case series, mainly focusing on economy class stroke syndrome. Data on the actual incidence, pathogenesis, and prognosis of stroke in commercial flights are lacking. METHODS:A prospective registry was designed to include all consecutive...

journal_title：Stroke

authors： Álvarez-Velasco R,Masjuan J,DeFelipe A,Corral I,Estévez-Fraga C,Crespo L,Alonso-Cánovas A

更新日期：2016-04-01 00:00:00

abstract：:The authors report an autopsy case with repeated transient ischemic attacks and subsequent strokes demonstrating evidence of artery-to-artery embolism from thrombi generated in the stenotic middle cerebral artery to the distal cortical branches. This case substantiates the existence of intracranial artery-to-artery em...

journal_title：Stroke

authors： Masuda J,Ogata J,Yutani C,Miyashita T,Yamaguchi T

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because the diagnosis and treatment of carotid artery disease may reduce the rate of stroke, the aim of this study was to determine whether a diet intervention was associated with incident carotid artery disease. METHODS:Participants were 48 835 postmenopausal women aged 50 to 79 years who were ...

journal_title：Stroke

authors： Allison MA,Aragaki A,Eaton C,Li W,Van Horn L,Daviglus ML,Berger JS

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The success of gait rehabilitation after stroke depends on active walking exercises. However, the disabling after-effects of stroke often make such exercises impossible at the onset of therapy. To facilitate treadmill training of paraparetic patients, a robot-driven gait orthosis (Lokomat) was de...

journal_title：Stroke

authors： Husemann B,Müller F,Krewer C,Heller S,Koenig E

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apolipoprotein E (ApoE) genotypes have been associated with lobar intracerebral hemorrhage (ICH). Although statins have been associated with an increased risk of ICH, meta-analyses have not consistently shown a statin-induced risk of ICH. Here, we test whether hypercholesterolemia (HC) and ApoE p...

journal_title：Stroke

authors： Woo D,Deka R,Falcone GJ,Flaherty ML,Haverbusch M,Martini SR,Greenberg SM,Ayres AM,Sauerbeck L,Kissela BM,Kleindorfer DO,Moomaw CJ,Anderson CD,Broderick JP,Rosand J,Langefeld CD,Woo JG

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Treatment of stroke patients in specialized stroke units has become more frequent, yet the effect of this treatment has not been determined. METHODS:In a community-based, prospective, and consecutive study of 1241 unselected acute stroke patients, we compared outcome of stroke treatment between ...

journal_title：Stroke

authors： Jørgensen HS,Nakayama H,Raaschou HO,Larsen K,Hübbe P,Olsen TS

更新日期：1995-07-01 00:00:00

abstract：:Acute cerebral circulatory changes following experimental cerebral hemorrhage were investigated in eight cats. The cerebral hemorrhage was produced in the right basal ganglia by introducing arterial blood via a thin catheter, using the systemic arterial blood pressure of the cat as a driving force. Local cerebral bloo...

journal_title：Stroke

authors： Kobari M,Gotoh F,Tomita M,Tanahashi N,Shinohara T,Terayama Y,Mihara B

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...

journal_title：Stroke

authors： Montaner J,Alvarez-Sabín J,Molina CA,Anglés A,Abilleira S,Arenillas J,Monasterio J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery of patients within the first 6 months after stroke is well documented, but there has been little research on long-term recovery. The aim of this study was to analyze functional and motor recovery between admission to rehabilitation centres and 5 years after stroke. METHODS:This follow-u...

journal_title：Stroke

authors： Meyer S,Verheyden G,Brinkmann N,Dejaeger E,De Weerdt W,Feys H,Gantenbein AR,Jenni W,Laenen A,Lincoln N,Putman K,Schuback B,Schupp W,Thijs V,De Wit L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...

journal_title：Stroke

authors： Grau AJ,Berger E,Sung KL,Schmid-Schönbein GW

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). METHODS:The primary composite en...

journal_title：Stroke

authors： Gonzales NR,Demaerschalk BM,Voeks JH,Tom M,Howard G,Sheffet AJ,Garcia L,Clair DG,Barr J,Orlow S,Brott TG,CREST Investigators.

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion magnetic resonance imaging (MRI) can quantitatively detect focal ischemic injury within minutes of onset, and perfusion MRI can evaluate the brain's microcirculation. N-Methyl-D-aspartate (NMDA) antagonists and reperfusion can reduce lesion size in stroke models. We used diffusion and p...

journal_title：Stroke

authors： Minematsu K,Fisher M,Li L,Sotak CH

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Findings on transesophageal echocardiography (TEE) after ischemic stroke predict recurrent embolic events and prompt therapy; however, the additive predictive power of TEE findings on long-term mortality is unknown. Our goal was to study the impact of TEE findings on all cause mortality in ischem...

journal_title：Stroke

authors： Ward RP,Don CW,Furlong KT,Lang RM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because best medical treatment is improving, the risk of stroke in asymptomatic carotid artery stenosis (ACAS) may decline. We evaluated the risk of ischemic stroke and stratified it according to stroke subtype in patients with ACAS during long-term follow-up. METHODS:In total, 4319 consecutive ...

journal_title：Stroke

authors： den Hartog AG,Achterberg S,Moll FL,Kappelle LJ,Visseren FL,van der Graaf Y,Algra A,de Borst GJ,SMART Study Group.

更新日期：2013-04-01 00:00:00

abstract：:Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

journal_title：Stroke

authors： Joseph R,Welch KM,D'Andrea G

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Downregulation of the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), is thought to be a novel neuroprotective strategy in ischemic stroke, but the underlying mechanisms remain unclear. In this study, we aimed to validate the use of PTEN regulation of gamma-amino...

journal_title：Stroke

authors： Liu B,Li L,Zhang Q,Chang N,Wang D,Shan Y,Li L,Wang H,Feng H,Zhang L,Brann DW,Wan Q

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. METHOD:The study cohort comprised 2283 patients who had received treatment for tuberculos...

journal_title：Stroke

authors： Sheu JJ,Chiou HY,Kang JH,Chen YH,Lin HC

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spreading depressions (SDs) occur in experimental focal ischemia and contribute to lesion evolution. N-Methyl-D-aspartate (NMDA) antagonists inhibit SDs and reduce infarct size. The glycine site on the NMDA receptor complex offers a therapeutic target for acute focal ischemia, potentially devoid ...

journal_title：Stroke

authors： Tatlisumak T,Takano K,Meiler MR,Fisher M

更新日期：1998-01-01 00:00:00

abstract：:Two patients with left middle cerebral artery (MCA) distribution infarctions fulfilled the "hot stroke" criteria on sequential 99m Tc pertechnetate flow and static gamma camera studies. The radioisotopic finding of a paradoxical relative increased flow to the affected hemisphere correlated with serial angiography show...

journal_title：Stroke

authors： Yarnell PR,Earnest MP,Sanders B,Burdick D

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...

journal_title：Stroke

authors： Muhonen MG,Sawin PD,Loftus CM,Heistad DD

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same tre...

journal_title：Stroke

authors： Kozak A,Ergul A,El-Remessy AB,Johnson MH,Machado LS,Elewa HF,Abdelsaid M,Wiley DC,Fagan SC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounte...

journal_title：Stroke

authors： Skolarus LE,Meurer WJ,Shanmugasundaram K,Adelman EE,Scott PA,Burke JF

更新日期：2015-07-01 00:00:00

abstract：:The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrova...

journal_title：Stroke

authors： Boysen G,Sørensen PS,Juhler M,Andersen AR,Boas J,Olsen JS,Joensen P

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent Icelandic studies have demonstrated linkage for common forms of stroke to chromosome 5q12 and association between phosphodiesterase4D (PDE4D) and ischemic stroke. Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Swe...

journal_title：Stroke

authors： Nilsson-Ardnor S,Wiklund PG,Lindgren P,Nilsson AK,Janunger T,Escher SA,Hallbeck B,Stegmayr B,Asplund K,Holmberg D

更新日期：2005-08-01 00:00:00

abstract：:The initial Stroke Therapy Academic Industry Roundtable (STAIR) recommendations published in 1999 were intended to improve the quality of preclinical studies of purported acute stroke therapies. Although recognized as reasonable, they have not been closely followed nor rigorously validated. Substantial advances have o...

journal_title：Stroke

authors： Fisher M,Feuerstein G,Howells DW,Hurn PD,Kent TA,Savitz SI,Lo EH,STAIR Group.

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute stroke care, rapid but careful evaluation of patients is mandatory but requires an experienced stroke neurologist. Telemedicine offers the possibility of bringing such expertise quickly to more patients. This study tested for the first time whether remote video examination is feasible an...

journal_title：Stroke

authors： Handschu R,Littmann R,Reulbach U,Gaul C,Heckmann JG,Neundörfer B,Scibor M

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:TIMI angiographic classification measures coronary residual flow and recanalization. We developed a Thrombolysis in Brain Ischemia (TIBI) classification by using transcranial Doppler (TCD) to noninvasively monitor intracranial vessel residual flow signals. We examined whether the emergent TCD TIB...

journal_title：Stroke

authors： Demchuk AM,Burgin WS,Christou I,Felberg RA,Barber PA,Hill MD,Alexandrov AV

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Do children have an increased risk for brain arteriovenous malformation (AVM) recurrence compared with adults and does this risk vary depending on initial presentation with AVM rupture? METHODS:We retrospectively studied 115 patients initially presenting with brain AVM under age 25 years who und...

journal_title：Stroke

authors： Copelan A,Drocton G,Caton MT,Smith ER,Cooke DL,Nelson J,Abla AA,Fox C,Amans MR,Dowd CF,Halbach VV,Higashida RT,Lawton MT,Kim H,Fullerton HJ,Gupta N,Hetts SW,UCSF Center For Cerebrovascular Research and UCSF Pediatric Br

更新日期：2020-10-01 00:00:00

abstract：:We studied ultrastructurally cerebral perforating arteries in 60 stroke-prone spontaneously hypertensive rats (SHRSP), which were sequentially killed at 4-52 weeks of age before showing symptoms of stroke. Another 24 SHRSP were killed soon after they showed symptoms of cerebral infarction. The initial vascular lesions...

journal_title：Stroke

authors： Tagami M,Nara Y,Kubota A,Sunaga T,Maezawa H,Fujino H,Yamori Y

更新日期：1987-07-01 00:00:00