The neostriatum: two entities, one structure?

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds w...

journal_title：Brain structure & function

authors： Häkkinen S,Rinne T

更新日期：2018-06-01 00:00:00

abstract：:Diffusion-weighted magnetic resonance spectroscopy of brain metabolites offers unique access to compartment-specific microstructural information on neural tissue. Here, we investigated in detail the diffusion characteristics of the neuronal/axonal markers N-acetylaspartate + N-acetyl aspartyl glutamate (tNAA) in a sma...

journal_title：Brain structure & function

authors： Ronen I,Budde M,Ercan E,Annese J,Techawiboonwong A,Webb A

更新日期：2014-09-01 00:00:00

abstract：:Coordinated modulation of sympathetic and parasympathetic nervous activity is required for physiological regulation of tissue function. Anatomically, whilst the peripheral sympathetic and parasympathetic pathways are separate, the distribution of premotor neurons in higher brain regions often overlaps. This co-distrib...

journal_title：Brain structure & function

authors： Hettigoda NS,Fong AY,Badoer E,McKinley MJ,Oldfield BJ,Allen AM

更新日期：2015-07-01 00:00:00

abstract：:The bulk of brain energy expenditure is allocated for maintenance of perpetual intrinsic activity of neurons and neural circuits. Long-term electrophysiological and neuroimaging studies in anesthetized and behaving animals show, however, that the great majority of nerve cells in the intact brain do not fire action pot...

journal_title：Brain structure & function

authors： Ovsepian SV

更新日期：2019-04-01 00:00:00

abstract：:Growing evidence indicates that physical exercise increases hippocampal volume. This has consistently been shown in mice and men using magnetic resonance imaging. On the other hand, histological studies have reported profound alterations on a cellular level including increased adult hippocampal neurogenesis after exer...

journal_title：Brain structure & function

authors： Biedermann SV,Fuss J,Steinle J,Auer MK,Dormann C,Falfán-Melgoza C,Ende G,Gass P,Weber-Fahr W

更新日期：2016-04-01 00:00:00

abstract：:An account of work performed at the UNA laboratories since 1992 on the detection and description of interlaminar glial processes, is presented. The incidental observation (serendipity) of longer than expected glial processes in the superficial layers of the cerebral cortex in hemiparkinsonian Cebus apella monkeys, was...

journal_title：Brain structure & function

authors： Colombo JA

更新日期：2017-04-01 00:00:00

abstract：:Sublineage diversification of specific neural cell classes occurs in complex as well as simply organized regions of the central and peripheral nervous systems; the significance of the phenomenon, however, remains insufficiently understood. The unipolar brush cells (UBCs) are glutamatergic cerebellar interneurons that ...

journal_title：Brain structure & function

authors： Sekerková G,Watanabe M,Martina M,Mugnaini E

更新日期：2014-03-01 00:00:00

abstract：:Rapid behavioral responses to unexpected events in the acoustic environment are critical for survival. Stimulus-specific adaptation (SSA) is the process whereby some auditory neurons respond better to rare stimuli than to repetitive stimuli. Most experiments on SSA have been performed under anesthesia, and it is unkno...

journal_title：Brain structure & function

authors： Duque D,Malmierca MS

更新日期：2015-11-01 00:00:00

abstract：:The basal ganglia of the laboratory rat consist of a few core regions that are specifically interconnected by efferents and afferents of the central nervous system. In nearly 800 reports of tract-tracing investigations the connectivity of the basal ganglia is documented. The readout of connectivity data and the collat...

journal_title：Brain structure & function

authors： Schmitt O,Eipert P,Kettlitz R,Leßmann F,Wree A

更新日期：2016-03-01 00:00:00

abstract：:A rapidly increasing number of studies are quantifying the system-level network architecture of the human brain based on structural-to-structural and functional-to-functional relationships. However, a largely unexplored area is the nature and existence of "cross-modal" structural-functional relationships, in which, fo...

journal_title：Brain structure & function

authors： Harms MP,Wang L,Csernansky JG,Barch DM

更新日期：2013-01-01 00:00:00

abstract：:Diffusion tensor histology holds great promise for quantitative characterization of structural connectivity in mouse models of neurological and psychiatric conditions. There has been extensive study in both the clinical and preclinical domains on the complex tradeoffs between the spatial resolution, the number of samp...

journal_title：Brain structure & function

authors： Wang N,Anderson RJ,Badea A,Cofer G,Dibb R,Qi Y,Johnson GA

更新日期：2018-12-01 00:00:00

abstract：:Stress-related psychiatric diseases are nearly twice as prevalent in women compared to men. We recently showed in male rats that the resident-intruder model of social stress differentially engages stress-related circuitry that regulates norepinephrine-containing neurons of the locus coeruleus (LC) depending on coping ...

journal_title：Brain structure & function

authors： Reyes BAS,Zhang XY,Dufourt EC,Bhatnagar S,Valentino RJ,Van Bockstaele EJ

更新日期：2019-05-01 00:00:00

abstract：:Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

journal_title：Brain structure & function

authors： Ramos-Moreno T,Clascá F

更新日期：2014-09-01 00:00:00

abstract：:Diverse stress stimuli induce long-lasting cognitive deficits, but the underlying molecular mechanisms are still incompletely understood. Here, we report three different stress models demonstrating that stress-inducible increases in microRNA-132 (miR-132) and consequent decreases in its acetylcholinesterase (AChE) tar...

journal_title：Brain structure & function

authors： Shaltiel G,Hanan M,Wolf Y,Barbash S,Kovalev E,Shoham S,Soreq H

更新日期：2013-01-01 00:00:00

abstract：:A loss-of-function polymorphism in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene has been linked to both drug abuse and schizophrenia. The α5 nAChR subunit is strategically positioned in the prefrontal cortex (PFC), where a loss-of-function in this subunit may contribute to cognitive disruptions in both...

journal_title：Brain structure & function

authors： Howe WM,Brooks JL,Tierney PL,Pang J,Rossi A,Young D,Dlugolenski K,Guillmette E,Roy M,Hales K,Kozak R

更新日期：2018-03-01 00:00:00

abstract：:We analyzed the developmental history of the subplate and related cellular compartments of the prenatal and early postnatal human cerebrum by combining postmortem histological analysis with in vivo MRI. Histological analysis was performed on 21 postmortem brains (age range: 26 postconceptional weeks to 6.5 years) usin...

journal_title：Brain structure & function

authors： Kostović I,Jovanov-Milošević N,Radoš M,Sedmak G,Benjak V,Kostović-Srzentić M,Vasung L,Čuljat M,Radoš M,Hüppi P,Judaš M

更新日期：2014-01-01 00:00:00

abstract：:Glucose metabolism produces, by oxidative phosphorylation, more than 15 times the amount of energy generated by aerobic glycolysis. Nonetheless, aerobic glycolysis remains a prevalent metabolic pathway in the brain. Here we review evidence suggesting that this pathway contributes essential molecules to the biomass of ...

journal_title：Brain structure & function

authors： Bauernfeind AL,Barks SK,Duka T,Grossman LI,Hof PR,Sherwood CC

更新日期：2014-07-01 00:00:00

abstract：:Manual volumetric measurement of the brain's frontal lobe and its subregions from magnetic resonance images (MRIs) is an established method for researching neural correlates of clinical disorders or cognitive functions. However, there is no consensus between methods used to identify relevant boundaries of a given regi...

journal_title：Brain structure & function

authors： Cox SR,Ferguson KJ,Royle NA,Shenkin SD,MacPherson SE,MacLullich AM,Deary IJ,Wardlaw JM

更新日期：2014-01-01 00:00:00

abstract：:The telencephalic subpallium is the source of various GABAergic interneuron cohorts that invade the pallium via tangential migration. Based on genoarchitectonic studies, the subpallium has been subdivided into four major domains: striatum, pallidum, diagonal area and preoptic area (Puelles et al. 2013; Allen Developin...

journal_title：Brain structure & function

authors： Puelles L,Morales-Delgado N,Merchán P,Castro-Robles B,Martínez-de-la-Torre M,Díaz C,Ferran JL

更新日期：2016-07-01 00:00:00

abstract：:Dopaminergic neuromodulation is critically important for brain and cognitive integrity. The DRD2/ANKK1 Taq1A polymorphism is associated with striatal dopamine (DA) D2 receptor availability. Some previous studies have found that the A allele of the Taq1A polymorphism influences brain structure, but the results are inco...

journal_title：Brain structure & function

authors： Li X,Papenberg G,Kalpouzos G,Bäckman L,Persson J

更新日期：2018-07-01 00:00:00

abstract：:The fornix is the primary efferent pathway of the hippocampus and plays a central role in memory circuitry. Diffusion tensor imaging has shown changes in the fornix with typical development and aging. Here, the fornix was investigated in 903 healthy young adult participants aged 22-36 years old from the high-spatial r...

journal_title：Brain structure & function

authors： Cahn AJ,Little G,Beaulieu C,Tétreault P

更新日期：2021-01-02 00:00:00

abstract：:Diffusion tensor imaging (DTI) has become a valuable tool to investigate white matter integrity in the brain. DTI also gives contrast in gray matter, which has been relatively little explored in studies assessing post-injury structural abnormalities. The present study was designed to compare white and gray matter reor...

journal_title：Brain structure & function

authors： Sierra A,Laitinen T,Gröhn O,Pitkänen A

更新日期：2015-03-01 00:00:00

abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:The architecture of the neocortex classically consists of six layers, based on cytological criteria and on the layout of intra/interlaminar connections. Yet, the comparison of cortical cytoarchitectonic features across different species proves overwhelmingly difficult, due to the lack of a reliable model to analyze th...

journal_title：Brain structure & function

authors： Cozzi B,De Giorgio A,Peruffo A,Montelli S,Panin M,Bombardi C,Grandis A,Pirone A,Zambenedetti P,Corain L,Granato A

更新日期：2017-08-01 00:00:00

abstract：:The tegmental pedunculopontine nucleus (PPN) is a basal ganglia-related structure that has recently gained renewed interest as a potential surgical target for the treatment of several aspects of Parkinson's disease. However, the underlying anatomical substrates sustaining the choice of the PPN nucleus as a surgical ca...

journal_title：Brain structure & function

authors： Barroso-Chinea P,Rico AJ,Conte-Perales L,Gómez-Bautista V,Luquin N,Sierra S,Roda E,Lanciego JL

更新日期：2011-11-01 00:00:00

abstract：:The midline and intralaminar thalamic nuclei (MITN), locus coeruleus (LC) and cingulate cortex contain nociceptive neurons. The MITN that project to cingulate cortex have a prominent innervation by norepinephrinergic axons primarily originating from the LC. The hypothesis explored in this study is that MITN neurons th...

journal_title：Brain structure & function

authors： Vogt BA,Hof PR,Friedman DP,Sikes RW,Vogt LJ

更新日期：2008-08-01 00:00:00

abstract：:Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

journal_title：Brain structure & function

authors： Güntürkün O,Verhoye M,De Groof G,Van der Linden A

更新日期：2013-01-01 00:00:00

abstract：:The auditory midbrain (inferior colliculus, IC) plays an important role in sound processing, acting as hub for acoustic information extraction and for the implementation of fast audio-motor behaviors. IC neurons are topographically organized according to their sound frequency preference: dorsal IC regions encode low f...

journal_title：Brain structure & function

authors： González-Palomares E,López-Jury L,García-Rosales F,Hechavarria JC

更新日期：2021-01-01 00:00:00

abstract：:Olfaction is one of the major sensory modalities that regulates food consumption and is in turn regulated by the feeding state. Given that the olfactory bulb has been shown to be a metabolic sensor, we explored whether the anterior piriform cortex (aPCtx)-a higher olfactory cortical processing area-had the same capaci...

journal_title：Brain structure & function

authors： Al Koborssy D,Palouzier-Paulignan B,Canova V,Thevenet M,Fadool DA,Julliard AK

更新日期：2019-01-01 00:00:00