Abstract：
:Epidemiological studies demonstrated that Helicobacter pylori (H. pylori) infection was associated with cardiovascular disease and its risk factors. However, the association between H. pylori infection and hypertension remained unclear. The aim of this study was to investigate the association between H. pylori infection and prevalence of hypertension among Chinese adults. We performed a cross-sectional study of 5246 adult participants who were recruited from a health manage center. All participants underwent a 13C-urea breath test and a routine health check-up. Logistic and liner regression models were used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to H. pylori infection. Of the 5168 study participants aged 18-70 years, 2034 (39.4%) were females and 955 (18.5%) had hypertension. After adjustment for potential confounders, H. pylori infection was associated with an increased prevalence of hypertension (OR, 1.23; 95% CI, 1.04, 1.46). In addition, compared with participants not infected with H. pylori, those with H. pylori infection had an increase of 0.735 mmHg (95% CI, 0.101, 1.369) for diastolic blood pressure and 0.723 mmHg (95% CI, 0.034, 1.413) for mean arterial pressure. There was no significant interaction between H. pylori infection and age, sex, and body mass index on the prevalence of hypertension (all P values for interaction >0.05). Findings from this study demonstrate that H. pylori infection was positively associated with prevalence of hypertension among Chinese adults. More well-designed studies are warranted to confirm our findings.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Wan Z,Hu L,Hu M,Lei X,Huang Y,Lv Ydoi
10.1038/s41371-017-0028-8subject
Has Abstractpub_date
2018-02-01 00:00:00pages
158-164issue
2eissn
0950-9240issn
1476-5527pii
10.1038/s41371-017-0028-8journal_volume
32pub_type
杂志文章abstract：:To investigate blood pressure (BP) as well as other risk factors before the onset of myocardial infarction in hypertensive patients, we analysed the BP and metabolic variables in 94 hypertensive patients who had been followed up in our out-patient clinic before the first onset (M1 group; n = 42, 69 +/- 1 years, mean +...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000697
更新日期：1998-10-01 00:00:00
abstract：:Hypertension is a serious public health threat worldwide. This study sought to explore gaps in urban Chinese adults' awareness and control of hypertension. A cross-sectional study was carried out in eight Chinese cities in 2016. Participants were organized into four groups on the basis of blood pressure (BP) and self-...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-018-0059-9
更新日期：2018-06-01 00:00:00
abstract：:Sudden death has been shown to be due in the majority of cases to ventricular arrhythmia. Left ventricular hypertrophy (LVH) may be implicated in the aetiology of some arrhythmia and sudden death. Recent evidence suggests that the relationship between LVH and arrhythmia may be complex and that there may be an interact...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1990-10-01 00:00:00
abstract：:The insertion/deletion polymorphism (I/D) of the angiotensin-converting enzyme (ACE) gene has been associated in some studies with a higher prevalence of left ventricular hypertrophy (LVH), but few of them were performed on pharmacologically treated hypertensive patients. The present study was undertaken to determine ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001005
更新日期：2000-05-01 00:00:00
abstract：:The assessment of sodium sensitivity requires to measure the difference in mean arterial pressure (MAP) at the end of sodium-loading (SLoad) and sodium-depletion (SDepl) maneuvers with an arm-cuff manometer. Aim of this study is to evaluate whether MAP measuring devices based on the volume-clamp method at the finger c...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2014.110
更新日期：2015-07-01 00:00:00
abstract：:Hypertension is strongly influenced by genetic factors. Although hypertension prevalence in some Hispanic sub-populations is greater than in non-Hispanic whites, genetic studies on hypertension have focused primarily on samples of European descent. A recent meta-analysis of 200 000 individuals of European descent iden...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析,多中心研究
doi：10.1038/jhh.2016.29
更新日期：2016-12-01 00:00:00
abstract：:A blood pressure recording is strictly speaking only relevant for the circumstances under which it is measured. There is increasing evidence that ambulatory recordings have more predictive power than casual BP recordings and are a better discriminator between high and low risk groups of patients, particularly within t...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-10-01 00:00:00
abstract：:The aim of this study was to assess the effect of alcohol on blood pressure and arterial compliance over 24 h in a group of volunteers, comparing the same group of subjects on two consecutive but separate days, one with alcohol intake (alcohol day) and one free of alcohol (control day). We studied 18 healthy subjects ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,随机对照试验
doi：10.1038/jhh.2015.19
更新日期：2016-01-01 00:00:00
abstract：:Hypertension has profound effects on various parts of the eye. Classically, elevated blood pressure results in a series of retinal microvascular changes called hypertensive retinopathy, comprising of generalized and focal retinal arteriolar narrowing, arteriovenous nicking, retinal hemorrhages, microaneurysms and, in ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/jhh.2011.37
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Disturbance in calcium metabolism has been suggested in the pathogenesis of hypertension, however, membrane calcium content in humans has not been studied in detail yet in primary hypertension. We compared plasma, intracellular and membrane calcium concentrations in erythrocytes of patients with essential hy...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001121
更新日期：2001-01-01 00:00:00
abstract：:Professional historians generally treat the phrase 'what if' with pardonable scorn. It is a speculation which necessarily will never be tested in the real world. Nevertheless, there is a reasonable likelihood that, if typhoid fever had not carried off Frederick Akbar Mahomed at the age of 35, clinical research in Brit...
journal_title：Journal of human hypertension
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:The current study comprehensively examined the association between common variants in the Na(+)-coupled bicarbonate transporter (NCBT) genes and blood pressure (BP) responses to dietary sodium intervention. A 7-day low-sodium followed by a 7-day high-sodium dietary intervention was conducted among 1906 Han participant...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/jhh.2015.113
更新日期：2016-09-01 00:00:00
abstract：:A deletion/insertion polymorphism in the ACE gene has been reported previously as a potent factor for myocardial infarction. We have tested the frequency of the deletion (D) allele of the ACE gene in 308 consecutive patients admitted to coronary care with chest pain. The gene frequencies were compared with those of 34...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:This multicentre, double-blind, trial in subjects with severe hypertension compared the efficacy and tolerability of two parallel drug regimens: A/B (amlodipine/benazepril: 5/20 or 10/40 mg daily, if necessary) with A (amlodipine: 5 or 10 mg daily, if necessary). The principal dependent variable was the proportion of ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/jhh.2009.80
更新日期：2010-06-01 00:00:00
abstract：:Studies on the possible association between blood pressure and blood lead have reached divergent conclusions. In a previous meta-analysis, a doubling of the blood lead concentration was associated with a 1.0/0.6 mm Hg increase in systolic and diastolic blood pressure (BP). This meta-analysis updates the analysis origi...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析
doi：10.1038/sj.jhh.1001300
更新日期：2002-02-01 00:00:00
abstract：:A clear relationship exists between elevated blood pressure (BP) and various manifestations of cardiovascular disease. Despite the availability of numerous treatment guidelines, hypertension remains inadequately controlled, with only a small proportion of patients achieving target BP levels. Many factors, both patient...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1002079
更新日期：2006-11-01 00:00:00
abstract：:We investigated whether inappropriately high left ventricular (LV) mass, defined as observed LV mass exceeding the level of individual LV mass predicted from gender, height, and stroke work, may be associated with an imbalance between growth-promoting and growth-inhibitory factors and/or structural vascular changes. I...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001720
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:Hypertension is an important public health problem, with some variability of its epidemiological properties in different populations. OBJECTIVES:The purpose of this study was to estimate the prevalence of hypertension and to determine the hypertension awareness, treatment and control rates in Aydin, a Turki...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000824
更新日期：1999-06-01 00:00:00
abstract：:The objective of this study was to examine the associations of red meat, poultry, and egg consumption with the risk of hypertension (HTN). The electronic databases of PubMed, Web of Science, and Embase were searched up to August 2017, for prospective cohort studies on the associations between red meat, poultry, or egg...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析
doi：10.1038/s41371-018-0068-8
更新日期：2018-07-01 00:00:00
abstract：:The World Hypertension League (WHL) International Art Competition started in 1991. The idea was to raise public awareness regarding hypertension prevention and treatment through unconventional means: Art. The purpose of this paper is to summarise the experience the WHL gained during preparation and follow-up activitie...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Prevalence, awareness, treatment and control of hypertension were assessed in 1032 (90%) of 1147 elderly (> or = 65 years) inhabitants of three Italian villages. Blood pressure (BP) was measured at home on two separate occasions following a standardised protocol. Persons taking antihypertensive drugs or with BP values...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001117
更新日期：2000-12-01 00:00:00
abstract：:We examined the association between serum lipoprotein subclasses and the three measures of arterial stiffness, that is, (i) carotid-femoral pulse wave velocity (cfPWV), which is a gold standard measure of central arterial stiffness, (ii) brachial-ankle PWV (baPWV), which is emerging as a combined measure of central an...
journal_title：Journal of human hypertension
pub_type： 杂志文章,多中心研究
doi：10.1038/jhh.2013.60
更新日期：2014-02-01 00:00:00
abstract：:Altitude affects blood pressure (BP) depending on duration and absolute altitude of exposure. Until now changes in BP during exposure to altitude were studied only in Caucasians. It is not known whether BP is affected differently in black and white people in response to altitude. During a 6-day climb on Kilimanjaro, B...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000468
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND:Hypertension is associated with increased urinary calcium excretion (UCa). A high sodium intake increases both UCa and blood pressure (BP). However, it is not clear whether these effects are modified by gender or ethnic origin. OBJECTIVES:To examine the relationships between BP, urinary sodium (UNa), gender...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001171
更新日期：2001-04-01 00:00:00
abstract：:In a 12 week randomised, double-blind study, a total of 31 patients with a sitting DBP of between 95 and 115 mmHg were enrolled for comparison of the antihypertensive, metabolic and antiplatelet effects of the drugs cilazapril and nifedipine retard. A two week placebo treatment was given before either cilazapril (2.5 ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-02-01 00:00:00
abstract：:Preeclampsia is a major complication of pregnancy. Risk factors for preeclampsia include population and regional ethnicity. Chinese women living outside the Chinese mainland have a lower prevalence of preeclampsia than resident Caucasians. We performed a retrospective study to identify potential factors that may be as...
journal_title：Journal of human hypertension
pub_type： 杂志文章,多中心研究
doi：10.1038/jhh.2013.148
更新日期：2014-11-01 00:00:00
abstract：:Platelet shape change (PSC) is an early phase of platelet activation that precedes platelet aggregation. This phase of platelet activation is essentially aspirin resistant. PSC was monitored, by measuring the median platelet volume (MPV) using a high resolution channelyser. Angiotensin (Ang) II, added in vitro, caused...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001102
更新日期：2000-09-01 00:00:00
abstract：:We sought to assess the haemodynamic effects of clonidine on left ventricular (LV) pressure-volume relation in patients with diastolic heart dysfunction due to essential hypertension. Towards this end, simultaneous recordings of LV volume (acoustic quantification) and LV pressure (micromanometer) were obtained in 10 s...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/sj.jhh.1001243
更新日期：2001-09-01 00:00:00
abstract：:Syst. China Trial aimed to determine whether titrated antihypertensive treatment could reduce the risk of stroke incidence and other cardiovascular complications among 2,298 older Chinese patients (> or = 60) with isolated systolic hypertension. The data from 3 years follow-up showed that the blood pressure reduction ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,评审
doi：
更新日期：1996-02-01 00:00:00
abstract：:To investigate the involvement of the sympathetic nervous system and cell membrane sodium transport in hypertensive cardiac hypertrophy, we divided 51 middle-aged male patients with essential hypertension into cardiac hypertrophy and noncardiac hypertrophy groups. We then compared the plasma noradrenaline concentratio...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
