Abstract:
AIMS:To define the prevalence of hypertension, a major cause of morbidity and mortality in blacks, and related biosocial factors in an urban African population group. METHODS:The setting was that of a civil service population in Ibadan, a major city in Southwestern Nigeria. Nine hundred and ninety-eight civil servants selected by multistage sampling participated in the survey. Biosocial data including smoking history, alcohol use and level of physical activity; anthropometry, blood pressure and plasma glucose measurements were obtained. Diagnosis of hypertension was based on blood pressure of > or =160/95 mm Hg or known hypertensive on treatment. RESULTS:The overall prevalence rate of hypertension was 10.3% (CI, 8.4%, 12.2%), rates of 13.9% and 5.3% were obtained in men and women respectively in spite of a much higher rate of generalised obesity in the latter. Hypertension was associated with higher salary grade level, but there was no relationship found with regular exercise, smoking and alcohol. Obesity (body mass index (BMI) > or =30 kg/m2) was associated with hypertension only in women. A two-sided t-test demonstrated age, waist circumference, waist to hip ratio (WHR) and plasma glucose level as significant variables. In multivariate ANOVA models of systolic blood pressures, age, male sex and BMI were highly significant factors (P < 0.0001) and plasma glucose was also significant (P < 0.016); the same variables (except plasma glucose) were associated with diastolic blood pressures. In logistic regression models the variables which predicted hypertension were WHR, plasma glucose, age, sex and family history of diabetes. CONCLUSIONS:Prevalence of hypertension in the study was comparable to recently reported rates in urban Nigeria and similar populations in Africa. The biosocial determinants of hypertension in the urban black population were age, male gender, higher socio-economic status, BMI, plasma glucose, generalised and central adiposity. Regional fat distribution was a stronger predictor of hypertension than generalised obesity in the population.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Olatunbosun ST,Kaufman JS,Cooper RS,Bella AFdoi
10.1038/sj.jhh.1000975subject
Has Abstractpub_date
2000-04-01 00:00:00pages
249-57issue
4eissn
0950-9240issn
1476-5527journal_volume
14pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract::For the epidemiologist, the development of any new therapy or strategy must respond to the following three questions: does a need exist? Is there a new way of meeting that need? Can a valid assessment be made of the efficacy of the new therapy? New antihypertensive treatments or strategies are needed, even in 1994: in...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::This article reviews the current literature regarding the role of home measurement of blood pressure (BP) in the management of hypertension. Subjects with hypertension can use simple automated devices to measure their own BP at home. The results can be accurate and reliable, and because multiple readings allow a mean ...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1001423
更新日期:2002-07-01 00:00:00
abstract::A Holter BP monitor and a noninvasive, continuous cardiac output (CO) monitor were concurrently attached to 25 middle-aged hospitalized patients with essential hypertension (EH). Blood pressure, heart rate (HR) and CO were measured every 10 minutes over 24 hours. Circadian variation of mean BP was studied. Comparison ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::Gender-specific determinants of blood pressure (BP) values and control have not been the focus of clinical hypertension research. The purpose of this analysis was to identify gender-specific and multi-level (physician and patient) determinants of BP values and predictors of uncontrolled BP. We completed a subgroup ana...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1038/jhh.2010.71
更新日期:2011-06-01 00:00:00
abstract::A total of 78 Chinese patients with clinically uncomplicated non-insulin-dependent diabetes (NIDDM) who had plasma creatinine concentrations of < 150 mumol/l were studied. Antihypertensive treatment was discontinued for at least six weeks prior to measurements of routine biochemistry, proteinuria, plasma atrial natriu...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::There are complications in diagnosing hypertension in children and adolescents due to variation of blood pressure (BP) values to age, gender and height. This study was aimed at assessing whether the performance of BP-to-height ratio (BPHR) can be an effective tool for screening prehypertension and hypertension in Elli...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2017.25
更新日期:2017-09-01 00:00:00
abstract::A neurogenic component to primary hypertension (hypertension) is now well established. Along with raised vasomotor tone and increased cardiac output, the chronic activation of the sympathetic nervous system in hypertension has a diverse range of pathophysiological consequences independent of any increase in blood pres...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2011.66
更新日期:2012-08-01 00:00:00
abstract::The objective of this study was to examine the relation between hypertension and depression. In a cross-sectional study of the urban region of a State capital with more than 1.5 million inhabitants, 1174 men and women aged 18-80 years, selected at random from the population, were studied. Blood pressure, hypertension ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1002017
更新日期:2006-06-01 00:00:00
abstract::To investigate the involvement of the sympathetic nervous system and cell membrane sodium transport in hypertensive cardiac hypertrophy, we divided 51 middle-aged male patients with essential hypertension into cardiac hypertrophy and noncardiac hypertrophy groups. We then compared the plasma noradrenaline concentratio...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::The prevalence, awareness and control of hypertension are important epidemiological research topics worldwide. The screening of hypertension in a workplace has some special aspects. We have screened the employees in a Hungarian salami factory (Pick Salami Factory, Szeged, Hungary) for hypertensives. In a cross-section...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001723
更新日期:2004-08-01 00:00:00
abstract::Hypertension has been associated with hyperinsulinemia and insulin resistance. The elevations in plasma insulin are the apparent adaptation of the pancreatic beta cell to the resistance to insulin. Maintenance of normal insulin release is therefore of great importance for subjects with hypertension. The potassium chan...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-04-01 00:00:00
abstract::Footshocks increases mean arterial pressure and heart rate. Systemic or intracerebroventricular (IVT) administration of losartan, a specific angiotensin AT1 receptor antagonist, not only inhibited the pressor response to footshocks but resulted in vasodepression. Peripheral or IVT administration of PD 123319, a specif...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000986
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:This study compares the antihypertensive efficacy and tolerability of valsartan, a novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs valsartan or HCTZ alone. DESIGN:871 adult out-patients with essential hypertension participated in this double-blind study. Patients were ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1038/sj.jhh.1000718
更新日期:1998-12-01 00:00:00
abstract::The 2017 American Academy of Pediatrics (AAP) guideline for assessing "elevated blood pressure (BP) (90th BP percentile)" and "high BP (95th BP percentile)" includes a large number of BP cut-offs based on sex, age and height, which makes it cumbersome to use in clinical practice. We developed and evaluated the perform...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-018-0128-0
更新日期:2019-03-01 00:00:00
abstract::This study aimed to test the role of family social support, depression, anxiety and self-efficacy on specific self-care behaviours. In a local community health center, 318 patients with hypertension completed a questionnaire assessing self-care, family social support, depression, anxiety and self-efficacy in 2012. Eac...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2014.58
更新日期:2015-03-01 00:00:00
abstract::The study objective was to compare blood pressure (BP) measurement by the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer. Comparison of simultaneous 'blind' BP measurements were made using the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer linked by a Y...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-05-01 00:00:00
abstract::We compared the effects on blood pressure (BP) of three isocaloric diets with reduced total fat and saturated fatty acid (SAFA) contents but with different proportions of monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA). Diet LF (low fat) provided 20 en% fat (7.9% SAFA, 7.8% MUFA, 3.0% PUFA); diet HP (hig...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.jhh.1000610
更新日期:1998-06-01 00:00:00
abstract::Previous studies have suggested that the Trp460 allele of the Gly460Trp polymorphism in the alpha-adducin gene is associated with salt sensitivity and primary hypertension. The present study was undertaken to evaluate if the Trp460 allele of this polymorphism is associated with primary hypertension in Scandinavians. T...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000942
更新日期:2000-01-01 00:00:00
abstract::Aortic pulse wave velocity has emerged as an important predictor of cardiovascular events, but data on ethnic differences in pulse wave velocity remain scarce. We explored differences in pulse wave velocity between people of Asian and African ancestry. Data were used from the cross-sectional Healthy Life in Suriname (...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-018-0144-0
更新日期:2020-02-01 00:00:00
abstract::Recent studies have shown that variability in home blood pressure has an important role in the progression of organ damage. The objective of this study was to investigate the factors that affect variability in home blood pressure in patients with type 2 diabetes. We assessed the relationship between home blood pressur...
journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
doi:10.1038/jhh.2014.2
更新日期:2014-10-01 00:00:00
abstract::The purpose of our study was to evaluate the behaviour of blood pressure (BP) by ambulatory monitoring of blood pressure (AMBP) in 53 patients with primary hyperparathyroidism (PHPT) compared to 100 essential hypertensive (EH) and 31 healthy subjects (HS). The correlations between calcium-phosphorus metabolism and hae...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001907
更新日期:2005-11-01 00:00:00
abstract::This report analysed data from the Health Survey for England 1994 to evaluate blood pressure (BP) management in relation to cigarette smoking. Data were analysed for 12 013 adults aged > or = 16 years living in England in 1994. Among 2280 subjects with BP > or = 160/95 mm Hg or treated with BP-lowering medication, rat...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001275
更新日期:2001-11-01 00:00:00
abstract::To evaluate ethnic differences in cerebral circulation, an index of carotid vascular resistance (RI) was determined by continuous wave Doppler ultrasound. Validation of the index resulted from a significant correlation between RI and carotid vascular resistance obtained from direct measurement of blood pressure and ca...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::For nearly two decades, the National High Blood Pressure Education Programme has administered a programme of public, patient, and professional education in an effort to reduce uncontrolled hypertension, an important public health problem in the USA. A broad network has been established and many partners have joined fo...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1992-12-01 00:00:00
abstract::Studies of populations or communities with no rise in blood pressure (BP) with advancing age and low prevalence of hypertension, may provide aetiological clues on the cause of hypertension. Within westernised societies, low blood pressures have been reported amongst chronic psychiatric in-patients and closed order sec...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000853
更新日期:1999-07-01 00:00:00
abstract::Blood pressure (BP) is known to vary by time of day and day of year. Studies differ substantially on the magnitude of the effect and there is doubt whether variation is clinically meaningful. We used more than 2 million BP measurements obtained between 1996 and 2004 from Geisinger Clinic primary care patients. General...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2008.44
更新日期:2008-11-01 00:00:00
abstract::We compared haemodynamic and humoral responses to nifedipine and nilvadipine in 25 elderly hypertensives. The study had a single-blind crossover design. Doppler flowmetry and laboratory examinations were performed before and after nifedipine and nilvadipine. Both nifedipine and nilvadipine significantly reduced mean a...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Altitude affects blood pressure (BP) depending on duration and absolute altitude of exposure. Until now changes in BP during exposure to altitude were studied only in Caucasians. It is not known whether BP is affected differently in black and white people in response to altitude. During a 6-day climb on Kilimanjaro, B...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000468
更新日期:1997-07-01 00:00:00
abstract::An appropriate cuff according to the individual's arm circumference is recommended with all blood pressure (BP) monitors. An electronic device for home monitoring has been developed (Visomat Comfort 20/40) that estimates the individual's arm circumference by measuring the cuff filing volume and makes an adjustment of ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2008.70
更新日期:2008-11-01 00:00:00
abstract::The National Blood Pressure Programme in Germany (NBP) was established in 1985. The NBP is committed to a process of programme development and implementation that incorporates public health relevance, recent research results, and attempts of scientific module evaluation. Among selected examples of successful modules, ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00