Abstract:
:Gender-specific determinants of blood pressure (BP) values and control have not been the focus of clinical hypertension research. The purpose of this analysis was to identify gender-specific and multi-level (physician and patient) determinants of BP values and predictors of uncontrolled BP. We completed a subgroup analysis comparing men and women who participated in the Belgian PREVIEW study of second-line treatment effectiveness of valsartan, applying two-level hierarchical modelling of 90-day BP values and guideline-defined BP control. In total, 1665 women and 1525 men were treated by 504 general practitioners. Fewer women than men reached systolic BP (SBP) (P=0.015) and combined BP targets at 90 days (P=0.007). More than 26% of the variance in 90-day SBP (intra-class correlation coefficient (ICC)=0.270) and diastolic BP (DBP) (ICC=0.262) was attributable to physician-level factors for men; the physician-level ICCs for SBP and DBP were 0.259 and 0.268, respectively, for women. Determinants of 90-day BP values and predictors of uncontrolled BP varied considerably by gender. Many of the multi-level determinants of BP by gender are amenable to intervention, and the remainder can serve as warning signs to clinicians that patients may remain vulnerable to poor outcomes associated with sub-optimal BP control.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
MacDonald K,Lee CS,Chen HC,Ko ML,Fidel GE,Brié H,Hermans C,Vancayzeele S,Reel S,Van der Niepen P,Abraham Idoi
10.1038/jhh.2010.71subject
Has Abstractpub_date
2011-06-01 00:00:00pages
372-82issue
6eissn
0950-9240issn
1476-5527pii
jhh201071journal_volume
25pub_type
临床试验,杂志文章,多中心研究abstract::Sudden death has been shown to be due in the majority of cases to ventricular arrhythmia. Left ventricular hypertrophy (LVH) may be implicated in the aetiology of some arrhythmia and sudden death. Recent evidence suggests that the relationship between LVH and arrhythmia may be complex and that there may be an interact...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::To investigate blood pressure (BP) as well as other risk factors before the onset of myocardial infarction in hypertensive patients, we analysed the BP and metabolic variables in 94 hypertensive patients who had been followed up in our out-patient clinic before the first onset (M1 group; n = 42, 69 +/- 1 years, mean +...
journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000586
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1991-06-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析
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journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
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更新日期:2006-06-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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更新日期:1992-04-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
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journal_title:Journal of human hypertension
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