Abstract：
:A Holter BP monitor and a noninvasive, continuous cardiac output (CO) monitor were concurrently attached to 25 middle-aged hospitalized patients with essential hypertension (EH). Blood pressure, heart rate (HR) and CO were measured every 10 minutes over 24 hours. Circadian variation of mean BP was studied. Comparison of values to the 6:00 value revealed a significant increase in mean BP during the active hours of the day. Mean BP during the sleeping hours, on the other hand, was significantly lower than during the awake hours. The circadian variations of CO and HR demonstrated similar fluctuations to those of mean BP. The circadian variation of the CO change ratio based on the 6:00 CO value was similar to that of mean BP. Circadian variation of total peripheral resistance (TPR) change ratio based on the 6:00 value demonstrated an inverse relation to the mean BP. It is suggested that the relation between TPR and CO in the circadian variation might be described as high output-low resistance.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Mori Hsubject
Has Abstractpub_date
1990-08-01 00:00:00pages
384-9issue
4eissn
0950-9240issn
1476-5527journal_volume
4pub_type
杂志文章abstract：:The study objective was to compare blood pressure (BP) measurement by the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer. Comparison of simultaneous 'blind' BP measurements were made using the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer linked by a Y...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-05-01 00:00:00
abstract：:The use of heart rate in clinical practice is limited by its variability under measurement situations. The mean heart rate on ambulatory monitoring provides a more robust statistic for clinical use. We examined the relationship between mean heart rate on initial referral ambulatory blood pressure monitoring (ABPM) to ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000586
更新日期：1998-04-01 00:00:00
abstract：:Hyperglycaemia, a raised fibrinogen, an increased serum triglyceride and a reduced HDL-cholesterol are common metabolic features of non-insulin dependent diabetes mellitus (NIDDM). Hypertension is frequently associated with NIDDM, however the influence of antihypertensive therapy on these combined factors in the diabe...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-10-01 00:00:00
abstract：:Prevalence, awareness, treatment and control of hypertension were assessed in 1032 (90%) of 1147 elderly (> or = 65 years) inhabitants of three Italian villages. Blood pressure (BP) was measured at home on two separate occasions following a standardised protocol. Persons taking antihypertensive drugs or with BP values...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001117
更新日期：2000-12-01 00:00:00
abstract：:Clinical studies have shown that aldosterone and salt are independently related to hypertension, cardiovascular morbidity and mortality. More recently, studies in humans have demonstrated that, similarly to animals, endogenous aldosterone and dietary salt intake have not only separate, but also combined effects to acc...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/jhh.2012.27
更新日期：2013-01-01 00:00:00
abstract：:This paper addresses approaches to evaluating the importance of different childhood behaviours on subsequent risk of high blood pressure and related cardiovascular risk factors and outlines results of a randomised controlled trial of nutrition and exercise interventions in schoolchildren. Clustering of cardiovascular ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-02-01 00:00:00
abstract：:Within routine clinical practice, white coat hypertension (where blood pressure is persistently higher in the presence of the doctor or nurse but normal outside the medical setting) makes the diagnosis and management of hypertension difficult. There are conflicting data regarding the prevalence and significance of whi...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/sj.jhh.1000924
更新日期：1999-12-01 00:00:00
abstract：:This article reviews the current literature regarding the role of home measurement of blood pressure (BP) in the management of hypertension. Subjects with hypertension can use simple automated devices to measure their own BP at home. The results can be accurate and reliable, and because multiple readings allow a mean ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1001423
更新日期：2002-07-01 00:00:00
abstract：:Renin-angiotensin (RAS) genes, a group of promising candidate genes involved in essential hypertension (EH), play a key role in blood pressure regulation. Recently, a series of novel RAS gene polymorphisms were reported, which significantly influence the rate of the gene transcription. This study was designed to explo...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2008.123
更新日期：2009-03-01 00:00:00
abstract：:Hypertension (HTN) related to health-promoting behaviors (HPB) and quality of life (QOL) in older Chinese has not been clearly identified. We sought to compare the HPB and QOL of elderly adults (aged ≥60) living with HTN in China to a community normotensive control group. Using multistage stratified cluster sampling, ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-018-0073-y
更新日期：2018-09-01 00:00:00
abstract：:This is the first report of long-term use (one year) of isradipine, a new dihydropyridine calcium channel blocker, in the treatment of elderly patients with essential hypertension. Patients completing a three month, double-blind, multicentre study comparing isradipine to hydrochlorothiazide (HCTZ) were eligible to enr...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1994-12-01 00:00:00
abstract：:The clinical correlates and risk profile of prediabetes (fasting plasma glucose (FPG) values in the upper normal limits but below the diabetic threshold) in hypertension, an insulin-resistant, prodiabetogenic condition, are scarcely known. For this reason, we evaluated 982 non-diabetic (FPG,<126 mg 100 ml(-1) and no a...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2008.142
更新日期：2009-05-01 00:00:00
abstract：:Both brachial blood pressure (BP) level and its variability (BPV) significantly associate with left ventricular (LV) structure and function. Recent studies indicate that aortic BP is superior to brachial BP in the association with LV abnormalities. However, it remains unknown whether aortic BPV better associate with L...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2017.37
更新日期：2017-10-01 00:00:00
abstract：:Randomized trials have shown significant blood pressure (BP) reductions after increased protein compared with carbohydrate intake, but the effect on BP maintenance after initial weight loss is unclear. We examined the effect of a high-protein diet on the maintenance of reduced BP after weight loss in 420 overweight ad...
journal_title：Journal of human hypertension
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/jhh.2014.30
更新日期：2015-01-01 00:00:00
abstract：:Established essential hypertension is characterised haemodynamically by a normal cardiac output and elevated total peripheral resistance. As hypertensive cardiovascular disease progresses, and the patient grows older, cardiac output falls and total peripheral resistance is further elevated. The activity of the renin-a...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:Elevated 2-h plasma glucose concentration (2hPG) from an oral glucose tolerance (OGTT) test more strongly predicts risk of subsequent cardiovascular disease than fasting plasma glucose (FPG), but the association between these glucose measurements and hypertension risk is less clear. We examined the association between...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1002316
更新日期：2008-03-01 00:00:00
abstract：:We lack non-invasive tools for evaluating the coronary and renal microcirculations. Since cutaneous Doppler laser exploration has evidenced impaired cutaneous microvascular responses in coronary artery disease and in impaired renal function, we wanted to find out if there was a link between the impairments in the cuta...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2010.117
更新日期：2012-01-01 00:00:00
abstract：:This study reports a correlation of alkaline phosphatase (AP) with diastolic blood pressure (DBP), and a reduction of alkaline phosphatase after chlorthalidone therapy that reached a nadir at three years of therapy, then gradually returned toward, but not reaching, baseline values. The data is from the baseline examin...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:The African population is considered a high-risk group for the development of hypertension, and identifying risk factors are therefore essential in preventive actions against cardiovascular disease (CVD). Elevated levels of uric acid (UA) are often associated with CVD. Our first aim was to establish possible ethnic di...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2010.1
更新日期：2010-10-01 00:00:00
abstract：:Inconsistent results have been reported regarding the association of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and hypertension. Recent studies of population-based samples of three different areas in Japan presented conflicting results regarding this association. We, thus, investiga...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001601
更新日期：2003-10-01 00:00:00
abstract：:Footshocks increases mean arterial pressure and heart rate. Systemic or intracerebroventricular (IVT) administration of losartan, a specific angiotensin AT1 receptor antagonist, not only inhibited the pressor response to footshocks but resulted in vasodepression. Peripheral or IVT administration of PD 123319, a specif...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000986
更新日期：2000-04-01 00:00:00
abstract：:This study investigated the period of time that blood pressure (BP) should be measured at home in older patients in order to obtain steady BP values. Thirty-six men and 38 women (> or =60 years) were recruited at one family practice. At one office visit the family physician measured supine, sitting and standing BPs th...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000517
更新日期：1997-10-01 00:00:00
abstract：:The phenomenon that blood pressure rises sharply in the morning is called 'Morning Blood Pressure Surge' (MBPS). Serum gamma-glutamyltransferase (GGT) is a proinflammatory marker involved in the pathogenesis of cardiovascular diseases. Although both are novel cardiovascular risk factors associated with inflammation an...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2014.74
更新日期：2015-05-01 00:00:00
abstract：:The accuracy of the TM-2420 ambulatory blood pressure monitor (A&D Co, Japan) has been assessed by the indirect method according to the recommendations of the Association for the Advancement of Medical Instrumentation (AAMI). Ninety subjects (43 men and 47 women), aged 19-89 with a range of systolic blood pressures (S...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:The aim of this study was to investigate the influence of ambient temperature on blood pressure (BP). BP measurements were taken in 20 normotensive volunteers who stayed in Greenland for a 6-week period. Measurements of systolic (SBP), diastolic (DBP) and heart rate (HR) were taken before (3 sessions), during (7-8 ses...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001134
更新日期：2001-02-01 00:00:00
abstract：:Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an important circulating serine protease in low-density lipoprotein cholesterol (LDL-C) metabolism. Increased plasma PCSK9 levels lead to increased plasma levels of LDL-C and an increased risk of cardiovascular disease (CVD). LDL-C is positively correlated with ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2017.56
更新日期：2017-11-01 00:00:00
abstract：:Previous studies have shown a relationship between coronary or carotid atherosclerosis and C-reactive protein (CRP) concentrations. In the present investigation, we evaluated the relationship between high-sensitivity CRP (hsCRP) concentrations and the presence of atherosclerotic lesions in the renal arteries and/or ab...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001878
更新日期：2005-07-01 00:00:00
abstract：:Maternal hypertension and preeclampsia are associated with greater risk of hypertension in childhood, and cardiovascular events in adulthood. However, whether preeclampsia affects blood pressure (BP) in the newborn period is unclear. Previous neonatal studies were based on small sample sizes, very low birth weight or ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2014.50
更新日期：2015-02-01 00:00:00
abstract：:The National Blood Pressure Programme in Germany (NBP) was established in 1985. The NBP is committed to a process of programme development and implementation that incorporates public health relevance, recent research results, and attempts of scientific module evaluation. Among selected examples of successful modules, ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Our study was aimed to assess the clinical correlates of different degrees of renal dysfunction in a wide group of non-diabetic hypertensive patients, free from cardiovascular (CV) complications and known renal diseases, participating to the REDHY (REnal Dysfunction in HYpertension) study. A total of 1856 hypertensive...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2009.41
更新日期：2010-01-01 00:00:00
