Abstract:
:The commonly used methods of estimating the 24-h urinary sodium (UNa) and urinary potassium (UK) from spot urine (SU) are the Kawasaki method (K-method), INTERSALT method (I-method), and Tanaka method (T-method), but the method that is suitable for use in the general Chinese population is still uncertain. We aimed to assess and validate these methods in estimating the 24-h UNa and UK using SU samples in Chinese adults. We studied 1428 individuals aged 18-69 years using SU and 24-h urine samples. For the K-method, I-method, and T-method, the Pearson correlation coefficients of the 24-h UNa were 0.35, 0.35, and 0.33 (all p < 0.01), and the intraclass correlation coefficients (ICC) were 0.34, 0.26, and 0.26 (all p < 0.01), respectively. The estimated 24-h UK using the K-method and T-method had correlation coefficients of 0.36 and 0.39 (all p < 0.01) and ICCs of 0.31 and 0.27 (all p < 0.01). The mean bias for the K-method in estimating the 24-h UNa and UK were the least biased among these methods. The bias between the 24-h urine Na/K ratio and the spot urinary Na/K ratio by the Bland-Altman method was -0.22. These methods for estimating the 24-h UNa and UK from SU were inadequate at the population level in Zhejiang Province, although the K-method showed the least bias among these methods. The spot urine Na/K ratio may be a useful and alternative method for 24-h urine collection for the estimation of the urinary Na/K ratio in the Chinese population.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Xu J,Du X,Bai Y,Fang L,Liu M,Ji N,Zhong J,Yu M,Wu Jdoi
10.1038/s41371-019-0274-zsubject
Has Abstractpub_date
2020-02-01 00:00:00pages
184-192issue
2eissn
0950-9240issn
1476-5527pii
10.1038/s41371-019-0274-zjournal_volume
34pub_type
杂志文章abstract::The current study comprehensively examined the association between common variants in the Na(+)-coupled bicarbonate transporter (NCBT) genes and blood pressure (BP) responses to dietary sodium intervention. A 7-day low-sodium followed by a 7-day high-sodium dietary intervention was conducted among 1906 Han participant...
journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::Despite the availability of multiple nonpharmacological and pharmacological antihypertensive regimens large scale control of BP on a population basis is still unsatisfactory. To achieve a better quality in hypertension care we have developed and evaluated a structured outpatient hypertension treatment and teaching pro...
journal_title:Journal of human hypertension
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doi:
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
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pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章
doi:10.1038/sj.jhh.1002020
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,多中心研究
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journal_title:Journal of human hypertension
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of human hypertension
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doi:
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