Abstract:
BACKGROUND:Blood-borne infections remain a risk of blood transfusions. While routine screening of donated blood products has greatly reduced the risk of human immunodeficiency virus, hepatitis B, and hepatitis C transmission, arboviruses such as dengue, chikungunya, and the West Nile virus remain significant risks especially during outbreaks. CASE REPORT:We report a rare case of dengue documented to be acquired through a blood transfusion, which resulted in severe thrombocytopenia prolonging admission in hospital in a neurosurgical patient. RESULTS:The donor of one of the units of red blood cells presented with dengue fever 2 days after donating. Sanger sequencing confirmed DENV-2 (dengue virus, Serotype 2) in both the donor and the patient samples and showed 100% nucleotide sequence identity between the two viruses, confirming transfusion-transmitted dengue infection. CONCLUSION:This case highlights the importance of arboviral screening of donor blood, especially for populations in endemic areas during outbreaks.
journal_name
Transfusionjournal_title
Transfusionauthors
Oh HB,Muthu V,Daruwalla ZJ,Lee SY,Koay ES,Tambyah PAdoi
10.1111/trf.13054subject
Has Abstractpub_date
2015-07-01 00:00:00pages
1655-61issue
7eissn
0041-1132issn
1537-2995journal_volume
55pub_type
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