Surfactant and noninvasive ventilation.

abstract：BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...

journal_title：Neonatology

authors： Yin X,Zhao J,Jiang H,Li L,Jiang J,Xi H,Peng X,Yin X,Shi X,Zhang L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia...

journal_title：Neonatology

authors： Koch A,Kreutzer K,von Oldershausen G,Poets CF,Bassler D,NEuroSIS Trial Group.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-ischemia (HI) results in increased activation of Ca2+/calmodulin kinase IV (CaM kinase IV) mediated by Src kinase. Therapeutic hypothermia ameliorates neuronal injury in the newborn. HYPOTHESIS:Inhibition of Src kinase concurrently with hypothermia further attenuates the hypoxia-induced increased ac...

journal_title：Neonatology

authors： Kratimenos P,Koutroulis I,Jain A,Malaeb S,Delivoria-Papadopoulos M

更新日期：2018-01-01 00:00:00

abstract：AIM:Melatonin is a potent free radical scavenger and an indirect antioxidant. Knowledge about the behavior of melatonin secretion in the early neonatal period, which may relate to its properties at a vital stage during very high antioxidant demands, is limited. PATIENTS AND METHODS:We studied 35 newborns admitted to t...

journal_title：Neonatology

authors： Muñoz-Hoyos A,Bonillo-Perales A,Avila-Villegas R,González-Ripoll M,Uberos J,Florido-Navío J,Molina-Carballo A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that color Doppler-measured cerebral blood flow velocity (CD-CBFV) as measured in the three feeding arteries of the brain can be used as an estimator of global cerebral blood flow. PATIENTS AND METHODS:CD-CBFV was determined as soon as possible after determination of phase-contrast magnetic ...

journal_title：Neonatology

authors： Benders MJ,Hendrikse J,de Vries L,Groenendaal F,van Bel F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Eye drop treatment routinely used to obtain mydriasis prior to fundoscopy in neonates requires repeated instillations of mydriatic agents that can lead to systemic side effects. OBJECTIVES:The aim of this study was to compare the mydriatic efficacy and tolerance of administration of phenylephrine and tropic...

journal_title：Neonatology

authors： Bremond-Gignac D,Jacqz-Aigrain E,Abdoul H,Daruich A,Beresniak A,Baud O,Alberti C,on behalf of the CLAIR FO Study Group.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Heart rate (HR) detection in premature infants using electrocardiography (ECG) is challenging due to a low signal amplitude and the fragility of the premature skin. Recently, the dynamic light scattering (DLS) technique has been miniaturized, allowing noninvasive HR measurements with a single sensor. OBJECT...

journal_title：Neonatology

authors： Gangaram-Panday NH,van Essen T,Goos TG,de Jonge RCJ,Reiss IKM,van Weteringen W

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown. OBJECTIVES:To elucidate the current utilization rate of inhaled corticosteroids in the prevention and th...

journal_title：Neonatology

authors： Maas C,Poets CF,Bassler D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:International neonatal resuscitation guidelines recommend assessing chest excursion when the heart rate is not improving. However, the accuracy in assessing 'adequate' chest excursion lacks objectivity. AIM:It was the aim of this study to test the accuracy in the assessment of 'adequate' chest excursion by ...

journal_title：Neonatology

authors： Brugada M,Schilleman K,Witlox RS,Walther FJ,Vento M,Te Pas AB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Retinopathy of prematurity (ROP) is a sight-threatening disease affecting extremely preterm infants. The introduction of new ROP screening surveillance systems, with higher sensitivity and specificity than established ROP screening guidelines, has the potential to reduce the number of stressful eye examinati...

journal_title：Neonatology

authors： Lundgren P,Stoltz Sjöström E,Domellöf M,Smith L,Wu C,VanderVeen D,Hellström A,Löfqvist C

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates. METHODS:In this prospective observational study, ...

journal_title：Neonatology

authors： Weisz DE,Jain A,McNamara PJ,EL-Khuffash A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurological morbidity in infants and children. Oxidative stress due to free radical formation and the initiation of abnormal oxidative reactions appears to play a key role. Docosahexanoic acid (DHA), a main component of ...

journal_title：Neonatology

authors： Solberg R,Longini M,Proietti F,Perrone S,Felici C,Porta A,Saugstad OD,Buonocore G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

journal_title：Neonatology

authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Transcutaneous bilirubin (TcB) devices are commonly used for screening of hyperbilirubinemia in term and near-term infants not exposed to phototherapy. However, the accuracy of TcB devices in infants exposed to phototherapy is unclear. OBJECTIVES:To conduct a systematic review of studies comparing TcB devic...

journal_title：Neonatology

authors： Nagar G,Vandermeer B,Campbell S,Kumar M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Intermittent hypoxic episodes are common among preterm infants, although longer term consequences on growth pattern and cardiovascular regulation are unclear. Furthermore, the effects of intermittent hypoxia (IH) may depend on the pattern of hypoxia-reoxygenation. OBJECTIVES:We tested the hypothesis that a ...

journal_title：Neonatology

authors： Pozo ME,Cave A,Köroğlu OA,Litvin DG,Martin RJ,Di Fiore J,Kc P

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Retinopathy of prematurity (ROP) is a gestational age (GA)-related illness that can lead to blindness in premature infants. Timely screening of premature infants could improve visual prognosis. OBJECTIVE:To evaluate the WINROP algorithm as a method of predicting severe ROP in a Chinese population. METHODS:...

journal_title：Neonatology

authors： Sun H,Kang W,Cheng X,Chen C,Xiong H,Guo J,Zhou C,Zhang Y,Hellström A,Löfqvist C,Zhu C

更新日期：2013-01-01 00:00:00

abstract：:Despite recent advances in the perinatal management of neonatal respiratory distress syndrome (RDS), controversies still exist. We report the updated recommendations of a European panel of expert neonatologists who had developed consensus guidelines after critical examination of the most up-to-date evidence in 2007. T...

journal_title：Neonatology

authors： Sweet DG,Carnielli V,Greisen G,Hallman M,Ozek E,Plavka R,Saugstad OD,Simeoni U,Speer CP,Halliday HL,European Association of Perinatal Medicine.

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:In high-risk newborns indirect hyperbilirubinemia can lead to acute bilirubin encephalopathy and kernicterus. Despite the current therapeutic modalities, preventing or reversing the neurotoxicity cannot be achieved in all infants. OBJECTIVE:To investigate the neuroprotective effects of hypothermia on biliru...

journal_title：Neonatology

authors： Kuter N,Aysit-Altuncu N,Ozturk G,Ozek E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Inflammation due to perinatal infection (PI) and perinatal asphyxia (PA) may cause damage to various tissues and very often to the immature brain of the fetus and the newborn. Previously, we have shown that the neonatal immune system has the ability to produce increased chemokine protein levels in the serum ...

journal_title：Neonatology

authors： Petrakou E,Mouchtouri A,Levi E,Lipsou N,Xanthou M,Fotopoulos S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Carriers of Staphylococcus aureus strains can be the source of epidemic infection for patients. OBJECTIVES:A molecular epidemiological analysis of an impetigo bullosa outbreak in a neonatal ward was performed in order to determine a potential source of the infection and possible routes of subsequent spreadi...

journal_title：Neonatology

authors： Jursa-Kulesza J,Kordek A,Kopron K,Wojciuk B,Giedrys-Kalemba S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES:The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine tempe...

journal_title：Neonatology

authors： Ng PL,Carlisle T,Ly M,Morris SA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Umbilical arterial catheters (UACs) are frequently used in critically ill neonates. UAC are convenient, reliable, and allow for caregiver convenience in performing painless arterial blood sampling. We hypothesized that UAC removal in extremely low birth weight (ELBW) neonates will result in significantly les...

journal_title：Neonatology

authors： Carroll PD,Zimmerman MB,Nalbant D,Gingerich EL,An G,Cress GA,Veng-Pedersen P,Widness JA

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Nosocomial infections endanger preterm infants. OBJECTIVE:The aim of the present controlled randomized trial was to investigate whether Bifidobacterium lactis reduces the incidence of nosocomial infections in infants with very low birth weight (VLBW; <1,500 g) <30 weeks of gestation. PATIENTS AND METHODS:I...

journal_title：Neonatology

authors： Mihatsch WA,Vossbeck S,Eikmanns B,Hoegel J,Pohlandt F

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...

journal_title：Neonatology

authors： Awada H,Al-Tannir M,Ziade MF,Alameh J,El Rajab M

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Oxidative stress in the newborn period may cause cell injury and inflammation if the antioxidant capacity is insufficient. To monitor antioxidant and inflammatory activity we examined by in vivo imaging various strains of luciferase reporter mice whose light-emitting properties were regulated by response e...

journal_title：Neonatology

authors： Dohlen G,Odland HH,Carlsen H,Blomhoff R,Thaulow E,Saugstad OD

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Pharmacological closure of patent ductus arteriosus (PDA) is commonly achieved by intravenous (IV) administration of ibuprofen or indomethacin. Occasionally, oral ibuprofen is used for PDA treatment although its efficacy and safety are unclear. OBJECTIVES:To systematically review randomized and quasi-random...

journal_title：Neonatology

authors： Neumann R,Schulzke SM,Bührer C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Ventilatory pressures should target the range between the upper and lower inflection point of the pressure volume curve in order to avoid atelecto- and volutrauma. During high-frequency oscillatory ventilation (HFOV), this range is difficult to determine. Quadrant impedance measurement (QIM) has recently bee...

journal_title：Neonatology

authors： Burkhardt W,Kurth F,Pitterle M,Blassnig N,Wemhöner A,Rüdiger M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Corticosteroids have been used widely after birth in preterm infants with respiratory failure; hydrocortisone may be preferable to other corticosteroids for this purpose. OBJECTIVES:To determine if postnatal hydrocortisone is useful to prevent or treat bronchopulmonary dysplasia (BPD) in preterm infants. M...

journal_title：Neonatology

authors： Doyle LW,Ehrenkranz RA,Halliday HL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The incidence of adverse tracheal intubation-associated events (TIAEs) and associated patient, practice, and intubator characteristics in the neonatal intensive care unit (NICU) setting are unknown. OBJECTIVES:To determine the incidence of adverse TIAEs and to identify factors associated with TIAEs in the N...

journal_title：Neonatology

authors： Foglia EE,Ades A,Napolitano N,Leffelman J,Nadkarni V,Nishisaki A

更新日期：2015-01-01 00:00:00