The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in vitro.

abstract：BACKGROUND:With the increasing incidence of births of very preterm very-low-birth-weight infants, there is a demand for echocardiographic reference values of cardiac dimensions. OBJECTIVES:The aim of this study was to provide reference values of cardiac valve annulus diameters in a cohort of extremely preterm very-low...

journal_title：Neonatology

authors： van Ark AE,Molenschot MC,Wesseling MH,de Vries WB,Strengers JLM,Adams A,Breur JMPJ

更新日期：2018-01-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is one of the few diseases in neonatal medicine that has continued to evolve since its first description about 50 years ago. Over these years, advancements in neonatal medicine such as antenatal steroids and exogenous surfactant therapy have significantly reduced neonatal mortality and...

journal_title：Neonatology

authors： Bancalari E,Jain D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Neonatal reference values of gallbladder size have been assessed in healthy newborns with enteral feeding regimen. Their applicability to critically ill patients under total parenteral nutrition (TPN) remains to be questioned. OBJECTIVE:Our aim was to evaluate the impact of short-term TPN versus enteral nut...

journal_title：Neonatology

authors： Schmidt B,Roth B,Stützer H,Benz-Bohm G

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Closed endotracheal suction interferes with mechanical ventilation received by infants, but the change to ventilation may be different when ventilator modes that target expired tidal volume (VT(e)) are used. OBJECTIVE:To measure airway pressure and tidal volume distal to the endotracheal tube (ETT) during a...

journal_title：Neonatology

authors： Kiraly NJ,Tingay DG,Mills JF,Dargaville PA,Copnell B

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:High-dose dexamethasone (DXM) treatment of preterms at risk of bronchopulmonary dysplasia leads to a deterioration in quality of their general movements (GMs). It is unknown whether low-dose DXM affects GM quality similarly. OBJECTIVES:To assess the effect of low-dose DXM treatment on the quality of GMs and...

journal_title：Neonatology

authors： Hitzert MM,Roescher AM,Bos AF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown. OBJECTIVES:To elucidate the current utilization rate of inhaled corticosteroids in the prevention and th...

journal_title：Neonatology

authors： Maas C,Poets CF,Bassler D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Preterm birth contributes significantly to infant mortality and morbidity, including blindness from retinopathy of prematurity (ROP). Access to intensive neonatal care is expanding in many countries, but care is not always optimal, one factor being that nursing is often by inadequately trained nurse assistan...

journal_title：Neonatology

authors： Gilbert C,Darlow B,Zin A,Sivasubramaniam S,Shah S,Gianini N,Beecroft G,Lopes Moreira ME

更新日期：2014-01-01 00:00:00

abstract：:Despite recent advances in the perinatal management of neonatal respiratory distress syndrome (RDS), controversies still exist. We report the updated recommendations of a European panel of expert neonatologists who had developed consensus guidelines after critical examination of the most up-to-date evidence in 2007. T...

journal_title：Neonatology

authors： Sweet DG,Carnielli V,Greisen G,Hallman M,Ozek E,Plavka R,Saugstad OD,Simeoni U,Speer CP,Halliday HL,European Association of Perinatal Medicine.

更新日期：2010-06-01 00:00:00

abstract：:Rites of passage mark important changes during human life and, for the neonate, its transition from intrauterine life into society. Their original intent was to purify the body from blood and meconium. But the cleansing rites had a spiritual dimension from the very start. When the rites of Mesopotamian, Egyptian, Jewi...

journal_title：Neonatology

authors： Obladen M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Alveolar development and lung parenchymal simplification are not well characterized in vivo in neonatal patients with respiratory morbidities, such as bronchopulmonary dysplasia (BPD). Hyperpolarized (HP) gas diffusion magnetic resonance imaging (MRI) is a sensitive, safe, nonionizing, and noninvasive biomar...

journal_title：Neonatology

authors： Higano NS,Thomen RP,Quirk JD,Huyck HL,Hahn AD,Fain SB,Pryhuber GS,Woods JC

更新日期：2020-11-11 00:00:00

abstract：OBJECTIVE:Therapeutic hypothermia (HT) is the standard treatment for newborns after perinatal asphyxia. Preclinical studies report that HT is more effective when started early. METHODS:Eighty cooled newborns were analyzed and grouped according to when cooling was started after birth: early (≤180 min) or late (>181 min...

journal_title：Neonatology

authors： Thoresen M,Tooley J,Liu X,Jary S,Fleming P,Luyt K,Jain A,Cairns P,Harding D,Sabir H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Despite increasing survival in the smallest preterm infants, the incidence of chronic lung disease has not decreased. Research into ventilatory strategies has concentrated on minimising barotrauma, volutrauma and atelectotrauma, but little attention has been paid to the role of bias gas flow rates and the po...

journal_title：Neonatology

authors： Bach KP,Kuschel CA,Oliver MH,Bloomfield FH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Substantial health care resources are expended on standardised formal neonatal resuscitation training (SFNRT) programmes, but their effectiveness has not been proven. OBJECTIVES:To determine whether SFNRT programmes reduce neonatal mortality and morbidity, improve acquisition and retention of knowledge and ...

journal_title：Neonatology

authors： Pammi M,Dempsey EM,Ryan CA,Barrington KJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE:To investigate the strength of associations and identify key risk factors shared by B...

journal_title：Neonatology

authors： Wang LW,Lin YC,Wang ST,Huang CC,on behalf of the Taiwan Premature Infant Developmental Collaborative Study Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...

journal_title：Neonatology

authors： EL-Khuffash A,McNamara PJ,Lapointe A,Jain A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...

journal_title：Neonatology

authors： Li ES,Görens I,Cheung PY,Lee TF,Lu M,O'Reilly M,Schmölzer GM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Retinopathy of prematurity (ROP) is a gestational age (GA)-related illness that can lead to blindness in premature infants. Timely screening of premature infants could improve visual prognosis. OBJECTIVE:To evaluate the WINROP algorithm as a method of predicting severe ROP in a Chinese population. METHODS:...

journal_title：Neonatology

authors： Sun H,Kang W,Cheng X,Chen C,Xiong H,Guo J,Zhou C,Zhang Y,Hellström A,Löfqvist C,Zhu C

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Strategies for oxygen therapy for preterm infants, such as the Vermont-Oxford's 'Breathsavers' guidelines, seek to strike a balance between the potential risks of the extremes of hyperoxia and hypoxia in preterm infants. Using an algorithm based on those guidelines, we aimed to compare the proportion of time...

journal_title：Neonatology

authors： Clarke A,Yeomans E,Elsayed K,Medhurst A,Berger P,Skuza E,Tan K

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Lipid peroxidation products are present following oxidation of polyunsaturated fatty acids in the eye, brain, and various cell membranes. Elevated levels of lipid peroxidation products and increased intermittent hypoxemia (IH) events have been associated with adverse outcomes in extremely preterm infants. ...

journal_title：Neonatology

authors： Shah VP,Raffay TM,Martin RJ,Vento M,Sánchez-Illana Á,Piñeiro-Ramos JD,Kuligowski J,Di Fiore JM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...

journal_title：Neonatology

authors： Awada H,Al-Tannir M,Ziade MF,Alameh J,El Rajab M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate whether a new MRI scoring system for preterm non-haemorrhagic white matter injury (WMI), derived from the analysis of the natural evolution of WMI throughout the neonatal period until term-equivalent age, can be used for outcome prediction. METHODS:Eighty-two infants <36...

journal_title：Neonatology

authors： Martinez-Biarge M,Groenendaal F,Kersbergen KJ,Benders MJNL,Foti F,van Haastert IC,Cowan FM,de Vries LS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:While hypoxic events with bradycardias are a frequent occurrence during the first weeks of life in preterm infants, the impact of preterm birth on maturation of the cardiovascular response to hypoxia in early postnatal life is unknown. OBJECTIVES:In the present study, we tested the hypothesis that preterm b...

journal_title：Neonatology

authors： Pladys P,Arsenault J,Reix P,Rouillard Lafond J,Moreau-Bussière F,Praud JP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Periventricular white matter (PWM) is particularly vulnerable in very preterm infants. Non-cystic white matter injury, known as non-cystic periventricular leukomalacia (ncPVL), is the commonest 'lesion' affecting the preterm brain. There is no consensus about whether ncPVL can be reliably identified from cer...

journal_title：Neonatology

authors： Graça AM,Cardoso K,Costa J,Cowan F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlu...

journal_title：Neonatology

authors： Van Ginderdeuren E,Allegaert K,Decaluwe H,Deprest J,Debeer A,Proesmans M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The lack of normative newborn serum ferritin concentration data between 23 and 41 weeks has led to difficulty in establishing the incidence and degree of abn...

journal_title：Neonatology

authors： Siddappa AM,Rao R,Long JD,Widness JA,Georgieff MK

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Newborns are prone to infections, which are independent predictors of neonatal mortality and morbidity. Neutrophil extracellular traps (NETs) are structures composed of chromatin and antimicrobial molecules that capture and kill pathogens. NETs may play an important role in the innate immune system and, thus...

journal_title：Neonatology

authors： Lipp P,Ruhnau J,Lange A,Vogelgesang A,Dressel A,Heckmann M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Newborns are susceptible to inflammatory diseases due to defects in clearing activated immune cells from tissues. Therefore, mechanisms have likely evolved to protect neonates from leukocyte-mediated cytotoxicity. Bilirubin has antioxidant activity, and it is possible that it also exerts effects on cellular ...

journal_title：Neonatology

authors： Weinberger B,Archer FE,Kathiravan S,Hirsch DS,Kleinfeld AM,Vetrano AM,Hegyi T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Small for gestational age (SGA) neonates are at increased risk of mortality and morbidity, including necrotizing enterocolitis (NEC), but detailed information on the incidence and risk factors of NEC in SGA neonates is lacking. OBJECTIVE:This study aims to estimate the incidence of NEC in a large cohort of ...

journal_title：Neonatology

authors： Ree IM,Smits-Wintjens VE,Rijntjes-Jacobs EG,Pelsma IC,Steggerda SJ,Walther FJ,Lopriore E

更新日期：2014-01-01 00:00:00

abstract：:This paper describes a neonate with type II Gaucher disease. The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure. Electron microscopy of the skin revealed lamellar body contents in the stratum corneum interstices, appearances consider...

journal_title：Neonatology

authors： Haverkaemper S,Marquardt T,Hausser I,Timme K,Kuehn T,Hertzberg C,Rossi R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:For quick detection or exclusion of neonatal early-onset bacterial infection (EOBI) or late-onset bacterial infection (LOBI), interleukin (IL)-6 is used. Its clinical use is sometimes limited due to prolonged recall times. Therefore, an IL-6 bedside test was established. OBJECTIVE:To compare the diagnostic ...

journal_title：Neonatology

authors： Batfalsky A,Lohr A,Heussen N,Neunhoeffer F,Orlikowsky TW

更新日期：2012-01-01 00:00:00