Abstract:
BACKGROUND:With the increasing incidence of births of very preterm very-low-birth-weight infants, there is a demand for echocardiographic reference values of cardiac dimensions. OBJECTIVES:The aim of this study was to provide reference values of cardiac valve annulus diameters in a cohort of extremely preterm very-low-birth-weight neonates and to correlate these with patient characteristics. METHODS:Valve diameters of 376 infants of < 32 weeks' gestation and with a birth weight of ≤2,000 g were measured using 2-dimensional echocardiography. Correlations between valve diameters and patient characteristics (birth length/weight, body surface area, gestational age, and sex) were assessed. Birth weight was used to establish linear regression models. Inter- and intraobserver agreement was assessed through intraclass correlation coefficient (ICC) analysis. RESULTS:Substantial variability was found (aortic valve mean [standard deviation; range]: 5.0 mm [0.6; 3.7-6.5]; pulmonic valve: 5.8 mm [0.8; 3.4-7.9]; mitral valve: 8.0 mm [1.0; 5.5-10.5]; tricuspid valve: 7.6 mm [1.2; 4.9-10.6]). There was a moderate correlation between birth weight and valve diameter (R2 aortic valve: 0.36; pulmonic valve: 0.20; mitral valve: 0.24; tricuspid valve: 0.24). Adequate intraobserver (ICC range 0.74-0.91) and interobserver agreement (ICC range 0.77-0.89) was found. CONCLUSIONS:Our study provides ready-to-use reference values for cardiac valve annulus diameters for extremely preterm infants.
journal_name
Neonatologyjournal_title
Neonatologyauthors
van Ark AE,Molenschot MC,Wesseling MH,de Vries WB,Strengers JLM,Adams A,Breur JMPJdoi
10.1159/000488387subject
Has Abstractpub_date
2018-01-01 00:00:00pages
198-204issue
3eissn
1661-7800issn
1661-7819pii
000488387journal_volume
114pub_type
杂志文章相关文献
Neonatology文献大全abstract:BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000255161
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:To compare the ultrasound examination with pH-metry in order to evaluate the diagnostic accuracy of sonography for diagnosis of gastro-oesophageal reflux (GOR) in preterm infants. METHODS:A prospective study was conducted on 31 premature infants <34 weeks with clinically diagnosed GOR. First, they underwent...
journal_title:Neonatology
pub_type: 临床试验,杂志文章
doi:10.1159/000097447
更新日期:2007-01-01 00:00:00
abstract:UNLABELLED:Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO2) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO2 can be used as an estimate of cerebral oxygen delivery. The SafeBoosC phase II randomised clinical trial hypothesises that the burden of hypo-...
journal_title:Neonatology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000351346
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Long-gap esophageal atresia (LGEA) may have clinical and syndromic presentations different from those of esophageal atresia (EA) that affects shorter segments of the esophagus (non-LGEA). This may suggest unique underlying developmental mechanisms. OBJECTIVES:We sought to characterize clinical differences b...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000449241
更新日期:2017-01-01 00:00:00
abstract::We describe three positive influenza AH1N1 cases in a neonatal unit during the influenza pandemic in Spain. One term baby presented with an upper respiratory tract infection, another preterm infant with an apnea episode following nosocomial infection, and thirdly, a term infant of a mother with influenza AH1N1 had sev...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000324232
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES:The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine tempe...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000464318
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Around 10% of newborn infants require assistance during transition after birth. Heart rate (HR) is the most important clinical indicator to evaluate the clinical status of a newborn. AIM:Our study aimed to review all established and novel methods to detect HR in babies giving special consideration to non-in...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000499675
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Eye drop treatment routinely used to obtain mydriasis prior to fundoscopy in neonates requires repeated instillations of mydriatic agents that can lead to systemic side effects. OBJECTIVES:The aim of this study was to compare the mydriatic efficacy and tolerance of administration of phenylephrine and tropic...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000493723
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:While hypoxic events with bradycardias are a frequent occurrence during the first weeks of life in preterm infants, the impact of preterm birth on maturation of the cardiovascular response to hypoxia in early postnatal life is unknown. OBJECTIVES:In the present study, we tested the hypothesis that preterm b...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000110868
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Corticosteroids have been used widely after birth in preterm infants with respiratory failure; hydrocortisone may be preferable to other corticosteroids for this purpose. OBJECTIVES:To determine if postnatal hydrocortisone is useful to prevent or treat bronchopulmonary dysplasia (BPD) in preterm infants. M...
journal_title:Neonatology
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000279992
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Small for gestational age (SGA) neonates are at increased risk of mortality and morbidity, including necrotizing enterocolitis (NEC), but detailed information on the incidence and risk factors of NEC in SGA neonates is lacking. OBJECTIVE:This study aims to estimate the incidence of NEC in a large cohort of ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000356033
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Oxidative stress in the newborn period may cause cell injury and inflammation if the antioxidant capacity is insufficient. To monitor antioxidant and inflammatory activity we examined by in vivo imaging various strains of luciferase reporter mice whose light-emitting properties were regulated by response e...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000107777
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Clinical illness caused by resistant bacteria usually represents a wider problem of asymptomatic colonization. Active surveillance with appropriate institution of isolation precautions represents a potential mechanism to control colonization and reduce infection. The neonatal intensive care unit (NICU) is an...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000343150
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Ventilatory pressures should target the range between the upper and lower inflection point of the pressure volume curve in order to avoid atelecto- and volutrauma. During high-frequency oscillatory ventilation (HFOV), this range is difficult to determine. Quadrant impedance measurement (QIM) has recently bee...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000345612
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Endogenous carbon monoxide (CO) production is primarily due to heme degradation, which also results in the equimolar production of bilirubin. Thus, estimates of total body CO production can serve as indices of total body bilirubin formation. The elimination rate of CO from a person's body (CO washout rate) a...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000503635
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:High-dose recombinant erythropoietin (rEpo) is neuroprotective in neonatal animal models of brain injury, but the long-term consequences of neonatal exposure have not been studied. OBJECTIVES:We hypothesized that multiple injections of high-dose rEpo during the neonatal period would be safe, and would impro...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000096969
更新日期:2007-01-01 00:00:00
abstract::Ductus arteriosus and foramen ovale were described by Galen without understanding their functions. His beliefs in soul localization and spiritization within the left ventricle established religious pneumatology which became a theological need in the Middle Ages. Pulmonary transit was recognized by Servetus and Colombo...
journal_title:Neonatology
pub_type: 历史文章,杂志文章
doi:10.1159/000308367
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Retinopathy of prematurity (ROP) is a sight-threatening disease affecting extremely preterm infants. The introduction of new ROP screening surveillance systems, with higher sensitivity and specificity than established ROP screening guidelines, has the potential to reduce the number of stressful eye examinati...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000435770
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...
journal_title:Neonatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000098376
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:In the absence of universal screening for congenital cytomegalovirus (cCMV) infection, the aim of this study was to assess the outcomes of a targeted screening protocol based on maternal and neonatal risk indicators. METHODS:The medical records of 2,623 neonates born in our maternal hospital between June 20...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000512525
更新日期:2020-12-22 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Restrictive use of invasive mechanical ventilation (IMV) in preterm infants reduces the risk of bronchopulmonary dysplasia (BPD). Our objective was to determine its effect on neurodevelopmental impairment (NDI) at 24 months' corrected age (CA). METHODS:This retrospective single-center cohort s...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000471841
更新日期:2017-01-01 00:00:00
abstract::Despite recent advances in the perinatal management of neonatal respiratory distress syndrome (RDS), controversies still exist. We report the updated recommendations of a European panel of expert neonatologists who had developed consensus guidelines after critical examination of the most up-to-date evidence in 2007. T...
journal_title:Neonatology
pub_type: 杂志文章,实务指引
doi:10.1159/000297773
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION:Lipid peroxidation products are present following oxidation of polyunsaturated fatty acids in the eye, brain, and various cell membranes. Elevated levels of lipid peroxidation products and increased intermittent hypoxemia (IH) events have been associated with adverse outcomes in extremely preterm infants. ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000509038
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Hyperglycaemia is a common complication of prematurity and is associated with neonatal mortality and morbidity, yet the aetiology is incompletely understood. C-peptide has been used in adults to estimate endogenous insulin secretion due to its simple clearance kinetics. OBJECTIVE:To determine insulin secret...
journal_title:Neonatology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000381206
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Newborns are susceptible to inflammatory diseases due to defects in clearing activated immune cells from tissues. Therefore, mechanisms have likely evolved to protect neonates from leukocyte-mediated cytotoxicity. Bilirubin has antioxidant activity, and it is possible that it also exerts effects on cellular ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000343097
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Phenobarbitone induces suppression of cerebral electrical activity on amplitude-integrated electroencephalography (aEEG) in neonates with hypoxic-ischemic encephalopathy (HIE); however, its effect during therapeutic hypothermia (TH) has not been well characterized. OBJECTIVE:To evaluate the effect of phenob...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000511540
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Transcutaneous bilirubin (TcB) devices are commonly used for screening of hyperbilirubinemia in term and near-term infants not exposed to phototherapy. However, the accuracy of TcB devices in infants exposed to phototherapy is unclear. OBJECTIVES:To conduct a systematic review of studies comparing TcB devic...
journal_title:Neonatology
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000442195
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Meconium displaces surfactant from the alveolar surface and inhibits its function. The development of active synthetic surfactants is complicated, especially to synthesize the hydrophobic surfactant proteins SP-B and SP-C. A synthetic surfactant, CHF5633 containing SP-B and SP-C analogs, has been designed to...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000356065
更新日期:2014-01-01 00:00:00
abstract::Volume resuscitation (VR) for the treatment of newborn shock is a rare but potentially lifesaving intervention. Conducting clinical studies to assess the effectiveness of VR in the delivery room during newborn stabilization is challenging. We review the available literature and current management guidelines to determi...
journal_title:Neonatology
pub_type: 杂志文章,评审
doi:10.1159/000475456
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000487220
更新日期:2018-01-01 00:00:00